J:BMC Womens Health

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT189299 Atp6v1e1 Positive_regulation of Htr2a 1 1 0.01 1.01 1.41
2 INT181492 NGF Regulation of TRPV1 1 1 0.21 0.93 1.31
3 INT181494 TRPV3 Regulation of Gene_expression of NGF 1 1 0.24 0.7 1.07
4 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 1 0.24 0.7 1.07
5 INT206857 Binding of Calca and Calcrl 4 2 0.37 1.9 0.95
6 INT189303 Atp6v1e1 Positive_regulation of Gene_expression of TPH1 1 1 0.01 0.16 0.73
7 INT177359 Serpinc1 Positive_regulation of CSRP1 1 1 0.00 0.97 0.72
8 INT177358 Ptger1 Positive_regulation of Localization of AMY2A 1 1 0.00 0.56 0.54
9 INT177357 Ptger1 Positive_regulation of Gene_expression of AMY2A 1 1 0.00 0.56 0.54
10 INT189300 Atp6v1e1 Regulation of Gene_expression of Prl 1 1 0.03 0.29 0.39
11 INT189301 Atp6v1e1 Positive_regulation of Positive_regulation of Htr2a 1 1 0.01 1.13 0.11
12 INT189298 Atp6v1e1 Positive_regulation of Positive_regulation of Htr1a 1 1 0.00 1.15 0.11
13 INT206856 Binding of Adm and Calcrl 1 2 0.04 1.76 0.1
14 INT206855 Binding of ESR1 and PPARA 1 1 0.03 1.21 0.07
15 INT206846 ESR1 Regulation of Gene_expression of PLP1 1 1 0.06 1.02 0.05
16 INT206897 Binding of HTR1A and Adm 1 1 0.02 0.87 0.05
17 INT206900 Binding of HTR1A and Calca 1 1 0.01 0.88 0.05
18 INT206848 PLP1 Regulation of Gene_expression of ESR1 1 1 0.07 0.9 0.04
19 INT206853 ESR1 Positive_regulation of Gene_expression of PCP4 1 2 0.08 1.39 0.04
20 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 1 0.07 0.9 0.04
21 INT206851 NR4A1 Regulation of Gene_expression of ESR1 1 1 0.08 0.9 0.04
22 INT206896 ESR1 Positive_regulation of Gene_expression of Nr1i3 1 1 0.00 0.36 0.04
23 INT206847 ESR1 Negative_regulation of Gene_expression of PTGER3 1 2 0.08 1.52 0.04
24 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 2 0.11 2.26 0.04
25 INT206852 ESR1 Regulation of Gene_expression of CRABP2 1 1 0.08 1.52 0.04
26 INT206898 Binding of PPARA and Rxrg 1 1 0.00 1.36 0.03
27 INT206895 Binding of ESR1 and Aldh1a1 1 1 0.03 0 0
28 INT206854 ESR1 Regulation of IGF1 1 1 0.01 0.33 0
29 INT197677 Binding of ESR1 and Arg1 1 1 0.04 0 0
30 INT206850 Binding of CRABP2 and ESR1 1 2 0.06 0 0
31 INT206844 ESR1 Positive_regulation of Gene_expression of ANXA1 1 1 0.08 0.1 0
32 INT197676 ESR1 Regulation of Gene_expression of Pgr 1 2 0.06 0.1 0
33 INT190902 Binding of HBN1 and Arsb 1 1 0.00 1.88 0
34 INT197675 Regulation of Binding of ESR1 and Arg1 1 1 0.05 0 0
35 INT206899 ESR1 Negative_regulation of Gene_expression of Calcrl 1 1 0.07 0.15 0
36 INT206843 Binding of ALDH1A1 and ESR1 1 1 0.07 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT18357 Gene_expression of TRPV1 3 825 0.78 307.11 382.81
3 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
4 INT9381 Positive_regulation of TRPV1 6 523 0.70 187.4 276.05
5 INT95787 Positive_regulation of Mapk1 1 568 0.70 226.51 220.94
6 INT6482 Positive_regulation of Gene_expression of TNF 1 659 0.70 569.88 210
7 INT15516 Gene_expression of Crp 1 711 0.77 615.33 173.09
8 INT15515 Positive_regulation of Crp 1 700 0.70 604.24 150.15
9 INT64161 Positive_regulation of Prkca 1 213 0.70 85.06 129.91
10 INT1281 Negative_regulation of Maoa 3 203 0.59 22.47 91.66
11 INT86024 Gene_expression of PPARA 6 736 0.78 497.93 91.14
12 INT62374 Gene_expression of NGF 7 158 0.78 77.87 76.45
13 INT822 Gene_expression of ESR1 13 529 0.78 302.16 63.64
14 INT67614 Positive_regulation of PPARA 2 438 0.68 293.28 63.61
15 INT2056 Negative_regulation of Gnrh1 1 175 0.59 33.43 63.32
16 INT31116 Gene_expression of Casp3 1 192 0.78 78.21 57.43
17 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
18 INT33567 Gene_expression of CALM1 7 139 0.67 48.85 56.14
19 INT64159 Gene_expression of Prkca 1 90 0.78 34.65 55.97
20 INT20375 Gene_expression of Hand1 1 213 0.60 148.51 54.53
21 INT3758 Gene_expression of ALB 1 326 0.78 184.65 38.75
22 INT9082 Positive_regulation of ESR1 6 238 0.69 148.51 36.69
23 INT103094 Binding of PPARA 1 308 0.47 177.26 34.75
24 INT23435 Positive_regulation of NGF 3 54 0.70 32.41 30.11
25 INT65597 Negative_regulation of Casp3 1 69 0.59 39.19 29.32
26 INT91775 Gene_expression of Slc6a4 1 102 0.78 26.45 28.23
27 INT20462 Binding of ESR1 9 210 0.44 102.7 26.34
28 INT95788 Positive_regulation of Positive_regulation of Mapk1 1 83 0.69 24.75 25.84
29 INT2614 Gene_expression of CGA 5 187 0.78 105.89 24.77
30 INT4809 Gene_expression of PTGDS 2 103 0.76 52.94 24.01
31 INT823 Negative_regulation of ESR1 2 144 0.58 63.72 22.52
32 INT2386 Gene_expression of Pgr 2 112 0.78 45.46 22.19
33 INT101517 Negative_regulation of PPARA 1 168 0.57 112.24 21.41
34 INT5916 Positive_regulation of HTR1A 1 51 0.67 18.27 21.38
35 INT1792 Positive_regulation of CGA 1 123 0.70 64.73 20.79
36 INT3952 Negative_regulation of ALB 1 116 0.59 72.18 18.35
37 INT94467 Positive_regulation of Hand1 1 71 0.58 59 16.96
38 INT7339 Localization of CALM1 1 46 0.75 16.15 16.47
39 INT84924 Positive_regulation of Gene_expression of NGF 1 29 0.68 17.91 16.46
40 INT3466 Gene_expression of Ptger1 1 39 0.75 18.34 15.75
41 INT2630 Positive_regulation of Shbg 1 134 0.70 65.26 15.19
42 INT100139 Positive_regulation of Gene_expression of PPARA 2 160 0.63 97.78 14.53
43 INT103547 Gene_expression of TRPV3 2 47 0.78 17.06 13.34
44 INT144646 Positive_regulation of Rela 1 53 0.67 27.78 13.2
45 INT27242 Gene_expression of PGR 2 153 0.75 98.77 12.79
46 INT3104 Negative_regulation of CGA 4 76 0.54 29.81 12.23
47 INT79545 Positive_regulation of Gene_expression of ESR1 4 82 0.64 39.42 12.18
48 INT85048 Regulation of NGF 4 19 0.62 11.61 10.5
49 INT115296 Gene_expression of TPH1 1 18 0.77 7.46 10.18
50 INT35835 Positive_regulation of Htr2a 11 17 0.67 10.68 9.81
51 INT122584 Negative_regulation of Gene_expression of PPARA 1 56 0.58 37.61 9.76
52 INT18121 Binding of Maoa 1 20 0.48 2.4 9.3
53 INT119098 Positive_regulation of TRPV3 4 20 0.68 10.12 9.01
54 INT34106 Negative_regulation of Htr1a 4 14 0.57 4.72 8.73
55 INT6133 Negative_regulation of Serpinc1 1 56 0.58 42.8 8.35
56 INT15687 Regulation of ESR1 7 91 0.60 40.42 7.95
57 INT6957 Positive_regulation of OXTR 1 38 0.70 6.55 7.81
58 INT4022 Negative_regulation of PLA2G1B 2 30 0.59 10.41 7.58
59 INT8793 Gene_expression of H2 3 58 0.75 26.36 7.07
60 INT110987 Transcription of ESR1 1 45 0.71 24.16 6.72
61 INT10785 Gene_expression of Prl 1 35 0.78 20.64 6.7
62 INT211363 Positive_regulation of RENBP 4 13 0.22 13.26 6.48
63 INT57256 Gene_expression of HLA-DQA2 1 52 0.55 23.87 6.27
64 INT35452 Gene_expression of Htr2a 5 11 0.65 5.11 6.1
65 INT29556 Negative_regulation of CALM1 1 26 0.57 9.08 6.04
66 INT149385 Positive_regulation of TRPV4 3 11 0.69 7.22 6.02
67 INT118440 Gene_expression of TRPV4 1 20 0.71 7.33 6.01
68 INT50050 Gene_expression of CSRP1 1 23 0.76 16.84 5.86
69 INT10147 Gene_expression of Serpinc1 1 28 0.76 17.73 5.77
70 INT59969 Positive_regulation of Htr1a 5 12 0.67 5.07 5.73
71 INT107619 Gene_expression of PTGER3 5 42 0.75 15 5.61
72 INT59718 Regulation of Htr1a 1 10 0.44 3.9 5.44
73 INT23010 Positive_regulation of CYP19A1 1 28 0.58 24.18 5.37
74 INT109246 Gene_expression of Calcrl 4 16 0.75 4.71 5.19
75 INT30738 Negative_regulation of Gene_expression of ALB 1 32 0.59 19.01 5.04
76 INT32256 Gene_expression of PLXNA3 1 11 0.75 7.8 4.92
77 INT21650 Regulation of OXTR 1 29 0.61 5.99 4.91
78 INT117204 Gene_expression of Tcm 2 39 0.58 10.58 4.88
79 INT48246 Gene_expression of PLP1 2 18 0.64 10.33 4.73
80 INT122675 Negative_regulation of Gene_expression of Slc6a4 1 14 0.59 6.4 4.69
81 INT109248 Gene_expression of Ramp1 1 8 0.72 2.45 4.69
82 INT91463 Positive_regulation of NFKB2 1 19 0.40 17.7 4.6
83 INT99020 Gene_expression of Nlrp3 1 23 0.75 18.86 4.4
84 INT28030 Binding of Otc 2 5 0.37 2.72 4.3
85 INT98057 Regulation of Htr2a 4 9 0.44 5.06 4.28
86 INT173926 Positive_regulation of Atp6v1e1 8 21 0.27 11.39 4.24
87 INT181495 Regulation of TRPV3 2 3 0.25 6.57 4.22
88 INT36133 Binding of pid 2 22 0.42 31.34 4.1
89 INT2924 Positive_regulation of sch 3 11 0.50 4.09 3.82
90 INT181922 Binding of RENBP 2 16 0.36 13.92 3.71
91 INT20461 Binding of Esr1 1 34 0.48 9.58 3.66
92 INT53516 Binding of CACNA1A 1 9 0.47 6.86 3.36
93 INT45324 Positive_regulation of Otc 2 8 0.59 3.94 3.36
94 INT10353 Positive_regulation of PGR 2 34 0.70 21.84 3.28
95 INT160153 Gene_expression of Htr1a 2 7 0.65 2.95 3.23
96 INT181496 Regulation of TRPV4 2 3 0.23 3.32 3.23
97 INT55002 Gene_expression of ASAP1 2 46 0.64 22.8 3.2
98 INT34604 Binding of Ada 1 11 0.31 4.15 3.1
99 INT134798 Gene_expression of ANXA1 4 15 0.75 13.94 2.99
100 INT33568 Phosphorylation of CALM1 1 10 0.55 2.31 2.91
101 INT2464 Gene_expression of AMY2A 1 21 0.75 13.76 2.78
102 INT95105 Gene_expression of TGFBR2 1 15 0.64 16.36 2.74
103 INT120515 Gene_expression of Otc 1 13 0.66 4.33 2.6
104 INT136850 Positive_regulation of Arg1 2 10 0.50 6.96 2.47
105 INT142741 Gene_expression of Atp6v1e1 4 28 0.31 9.41 2.34
106 INT86083 Positive_regulation of Htr1b 1 5 0.45 2.01 2.05
107 INT122924 Binding of ipv 5 27 0.42 31.81 1.99
108 INT46559 Gene_expression of pid 2 11 0.58 13.1 1.93
109 INT126906 Positive_regulation of Gene_expression of H2 1 12 0.21 9.2 1.91
110 INT2116 Negative_regulation of VSX1 1 29 0.36 10.67 1.89
111 INT93886 Positive_regulation of Gene_expression of PGR 2 19 0.52 15.78 1.89
112 INT195817 Gene_expression of ipv 2 28 0.58 31.04 1.86
113 INT26850 Negative_regulation of H2 2 13 0.32 9.4 1.82
114 INT36132 Negative_regulation of pid 1 12 0.43 15.15 1.73
115 INT15969 Negative_regulation of Ar 1 11 0.43 2.77 1.59
116 INT94614 Binding of PTGER3 1 7 0.35 2.54 1.58
117 INT11831 Positive_regulation of pid 3 13 0.40 23.37 1.54
118 INT127767 Negative_regulation of Atp6v1e1 4 9 0.23 5.66 1.52
119 INT189286 Regulation of Gene_expression of Htr2a 1 1 0.01 1.12 1.49
120 INT189302 Positive_regulation of Gene_expression of HLA-DQA2 2 6 0.06 4.44 1.48
121 INT128936 Positive_regulation of Gene_expression of PTGER3 3 12 0.67 3.08 1.45
122 INT62296 Gene_expression of PDXP 1 8 0.67 6.48 1.44
123 INT173928 Regulation of Atp6v1e1 3 11 0.16 3.77 1.43
124 INT238653 Regulation of MTX1 1 2 0.30 1.71 1.42
125 INT189290 Positive_regulation of Positive_regulation of Htr2a 3 1 0.02 2.51 1.41
126 INT119062 Negative_regulation of BRCA1 1 12 0.49 13.7 1.36
127 INT38964 Negative_regulation of Lsd 1 3 0.37 0.52 1.32
128 INT1957 Localization of AMY2A 1 6 0.68 2.85 1.31
129 INT81400 Binding of RARA 1 25 0.36 12.93 1.27
130 INT44917 Negative_regulation of Gene_expression of PTGDS 1 6 0.50 2.98 1.27
131 INT89765 Positive_regulation of NR4A1 1 12 0.69 8.13 1.23
132 INT180588 Gene_expression of HEYL 2 13 0.52 8.37 1.19
133 INT25710 Regulation of Igf2 1 6 0.62 3.1 1.17
134 INT180580 Binding of HEYL 2 7 0.17 4.49 1.15
135 INT203646 Gene_expression of STIP1 3 26 0.63 23.57 1.14
136 INT189287 Binding of Atp6v1e1 2 7 0.19 6.9 1.14
137 INT216858 Negative_regulation of PID1 1 4 0.35 6.3 1.11
138 INT181497 Regulation of Regulation of TRPV4 1 1 0.23 0.69 1.08
139 INT27938 Negative_regulation of Pgr 1 12 0.38 1.98 1.05
140 INT35451 Negative_regulation of Gene_expression of Htr2a 1 2 0.35 0.34 1.04
141 INT160280 Positive_regulation of ipv 1 14 0.44 15.73 1.02
142 INT89774 Gene_expression of NR4A1 2 13 0.77 9.47 1.02
143 INT107618 Positive_regulation of PTGER3 3 10 0.41 1.82 1.01
144 INT128937 Negative_regulation of PTGER3 1 8 0.23 4.49 1.01
145 INT71906 Regulation of Gene_expression of ESR1 4 22 0.41 11.01 0.98
146 INT128609 Gene_expression of C1S 1 18 0.75 17.36 0.98
147 INT156727 Gene_expression of Arg1 3 4 0.44 2.1 0.97
148 INT47039 Regulation of SFRP1 1 14 0.62 7.44 0.92
149 INT24410 Negative_regulation of Gene_expression of Serpinc1 1 4 0.28 1.98 0.91
150 INT34779 Regulation of IGF2 1 7 0.38 4.34 0.9
151 INT119324 Positive_regulation of Gene_expression of Ramp1 1 3 0.53 0.94 0.89
152 INT163889 Regulation of Gene_expression of Calcrl 1 3 0.21 1 0.84
153 INT174728 Positive_regulation of Transcription of ESR1 1 10 0.47 3.3 0.83
154 INT107063 Gene_expression of Nr1i3 1 5 0.67 0.72 0.76
155 INT173930 Positive_regulation of Gene_expression of Atp6v1e1 1 4 0.17 0.46 0.71
156 INT91398 Regulation of RARA 1 7 0.59 5.84 0.67
157 INT216867 Localization of PDXP 2 4 0.28 6.31 0.62
158 INT17493 Binding of Ar 1 14 0.48 3.62 0.6
159 INT143398 Regulation of ELL 3 2 0.44 2.17 0.59
160 INT189289 Negative_regulation of Gene_expression of H2 1 4 0.18 1.27 0.56
161 INT165456 Positive_regulation of NAF1 1 3 0.42 0.77 0.56
162 INT3831 Negative_regulation of TGFBR2 2 4 0.28 4.99 0.55
163 INT185916 Gene_expression of NAF1 15 16 0.65 4.27 0.53
164 INT192094 Binding of Rxrg 2 5 0.05 4.38 0.52
165 INT206876 Positive_regulation of Gene_expression of ANXA1 2 3 0.39 1.68 0.51
166 INT110165 Negative_regulation of Arg1 3 8 0.38 3.21 0.48
167 INT206880 Gene_expression of ALDH1A1 4 5 0.45 5.02 0.45
168 INT206864 Transcription of PTGDS 2 3 0.45 1.04 0.45
169 INT206858 Regulation of ANXA1 1 3 0.56 2.4 0.45
170 INT197674 Positive_regulation of Gene_expression of Arg1 1 2 0.33 0.63 0.44
171 INT189283 Gene_expression of MHC II protein 2 1 0.23 1.63 0.39
172 INT136851 Regulation of Arg1 3 7 0.38 3.05 0.37
173 INT190900 Binding of Arsb 3 5 0.35 17.18 0.35
174 INT176586 Positive_regulation of Binding of ESR1 2 11 0.41 4.64 0.33
175 INT109245 Positive_regulation of Gene_expression of Calcrl 1 3 0.67 0.89 0.3
176 INT189284 Positive_regulation of Negative_regulation of Atp6v1e1 1 2 0.20 1.82 0.28
177 INT173223 Negative_regulation of BRCA2 1 7 0.54 6.79 0.25
178 INT89769 Positive_regulation of Gene_expression of NR4A1 1 4 0.69 2.83 0.23
179 INT189297 Transcription of Atp6v1e1 1 2 0.24 1.54 0.23
180 INT189293 Positive_regulation of Gene_expression of MHC class II protein 1 1 0.14 1.05 0.23
181 INT189288 Negative_regulation of Negative_regulation of H2 1 1 0.06 0.47 0.23
182 INT96972 Positive_regulation of Binding of Esr1 1 4 0.22 1.35 0.21
183 INT198393 Transcription of pid 1 2 0.51 2.01 0.2
184 INT189291 Negative_regulation of Negative_regulation of Htr1a 1 1 0.01 1.56 0.2
185 INT185915 Binding of NAF1 1 1 0.31 0.36 0.19
186 INT185913 Positive_regulation of Binding of NAF1 1 1 0.42 0.36 0.19
187 INT89764 Binding of NR4A1 1 2 0.42 2.22 0.17
188 INT206869 Gene_expression of ALDH1A2 1 3 0.38 2.51 0.16
189 INT189295 Negative_regulation of Gene_expression of MHC II protein 1 1 0.13 0.58 0.16
190 INT206888 Negative_regulation of Gene_expression of Calcrl 1 2 0.26 0.83 0.13
191 INT178053 Positive_regulation of STIP1 3 7 0.44 5.09 0.11
192 INT178054 Regulation of STIP1 1 2 0.31 2.38 0.1
193 INT206872 Regulation of NR4A1 2 3 0.17 1.11 0.07
194 INT206860 Binding of CRABP2 1 1 0.19 0.52 0.07
195 INT316393 Binding of SULT2A1 2 1 0.35 0.07 0.07
196 INT189292 Negative_regulation of Regulation of Htr2a 1 1 0.02 1.01 0.07
197 INT206877 Positive_regulation of PCP4 2 1 0.21 1.68 0.06
198 INT184935 Protein_catabolism of Ace2 1 1 0.08 0.21 0.06
199 INT206866 Positive_regulation of SFRP1 1 7 0.51 3.97 0.05
200 INT206890 Negative_regulation of Gene_expression of Ramp1 1 1 0.18 0.83 0.05
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