J:Basic Clin. Pharmacol. Toxicol.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT167169 Nfkb1 Regulation of Gene_expression of Crp 1 4 0.09 1.76 1.38
2 INT150514 Decr1 Positive_regulation of Gsr 1 1 0.13 0.24 0.24
3 INT154914 UGT1A9 Regulation of IGHD6-6 1 1 0.05 0 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT64202 Positive_regulation of Trpv1 1 643 0.70 249.66 397.42
2 INT34869 Negative_regulation of PTGS2 2 778 0.59 366.76 319.85
3 INT5379 Gene_expression of Fos 2 656 0.78 255.5 292.54
4 INT87687 Positive_regulation of Trpv1 1 409 0.70 210.24 257.59
5 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
6 INT9987 Gene_expression of Abat 1 296 0.78 95.46 226.34
7 INT6488 Gene_expression of Tnf 1 484 0.78 339.61 191.58
8 INT15516 Gene_expression of Crp 5 711 0.77 615.33 173.09
9 INT4740 Gene_expression of Th 2 298 0.78 61.27 154.03
10 INT5380 Positive_regulation of Gene_expression of Fos 1 243 0.70 105.65 131.05
11 INT218 Positive_regulation of Th 1 245 0.70 40.5 120.1
12 INT50674 Gene_expression of PTGS2 1 459 0.78 253.33 118.51
13 INT7327 Regulation of Th 4 164 0.62 29.67 110.14
14 INT54571 Positive_regulation of NFKB1 6 263 0.70 138.99 87.32
15 INT15769 Gene_expression of Il1b 1 146 0.78 114.51 75.35
16 INT6656 Gene_expression of YY1 1 135 0.75 24.73 72.16
17 INT15913 Negative_regulation of CYP2D6 1 174 0.59 22.45 70.91
18 INT217 Negative_regulation of Th 1 134 0.59 26.83 62.63
19 INT8528 Negative_regulation of Gene_expression of Fos 1 100 0.59 41.15 55.6
20 INT12345 Gene_expression of Il2 1 142 0.78 59.17 51.21
21 INT109430 Positive_regulation of Trpa1 1 119 0.70 44 49.14
22 INT52531 Gene_expression of Nfkb1 2 153 0.75 82.84 42.9
23 INT50957 Negative_regulation of Il6 1 134 0.59 79.08 42.67
24 INT11560 Positive_regulation of CASP3 1 236 0.70 184.33 39.38
25 INT96624 Positive_regulation of Positive_regulation of Trpv1 1 62 0.70 20.5 34.28
26 INT6558 Positive_regulation of Gene_expression of Th 1 56 0.70 9.64 30.89
27 INT72375 Phosphorylation of Mapk3 1 87 0.80 43.66 30.27
28 INT56072 Negative_regulation of NFKB1 2 94 0.59 53.16 28.19
29 INT12681 Regulation of Trib3 1 76 0.53 23.92 26.58
30 INT5378 Regulation of Gene_expression of Fos 1 47 0.60 14.47 26.41
31 INT26719 Negative_regulation of Gene_expression of Th 1 38 0.58 11.87 22.78
32 INT66208 Positive_regulation of Positive_regulation of NFKB1 1 45 0.68 20.17 22.62
33 INT15326 Phosphorylation of Trib3 2 83 0.55 30.96 22.27
34 INT104707 Gene_expression of Em 1 16 0.65 3.95 22.19
35 INT60779 Negative_regulation of CYP3A 2 63 0.59 8.38 21.27
36 INT50404 Negative_regulation of CYP1A2 5 49 0.59 8.61 17.35
37 INT65856 Positive_regulation of TP53 1 138 0.67 112.65 16.71
38 INT101119 Negative_regulation of Comt 1 19 0.58 8.77 13.09
39 INT48927 Regulation of Mapk3 1 25 0.60 14.06 12.82
40 INT14334 Negative_regulation of Il2 1 31 0.58 18.63 11.08
41 INT33127 Positive_regulation of Phosphorylation of Trib3 1 26 0.17 14.04 10
42 INT46054 Gene_expression of Decr1 1 39 0.65 12.82 9.48
43 INT92822 Negative_regulation of Gene_expression of Crp 4 36 0.49 29.5 8.83
44 INT44537 Positive_regulation of Comt 1 7 0.69 2.62 7.78
45 INT65489 Regulation of Gene_expression of Crp 1 28 0.59 29.17 7.56
46 INT101121 Regulation of Comt 1 19 0.53 10.66 7.22
47 INT102749 Positive_regulation of Positive_regulation of CASP3 1 32 0.67 26.07 6.93
48 INT143234 Gene_expression of Nfkbia 1 10 0.62 5.2 5.02
49 INT95538 Localization of CYP2D6 2 21 0.81 5.69 4.73
50 INT61366 Positive_regulation of NFASC 2 16 0.26 13.75 4.11
51 INT73557 Positive_regulation of RELA 1 57 0.46 8.7 3.43
52 INT104708 Gene_expression of Msh3 1 6 0.72 0.07 3.17
53 INT139801 Phosphorylation of NFKB1 2 9 0.66 5.2 3.13
54 INT14911 Gene_expression of Ddx20 1 6 0.05 0.26 3.06
55 INT82966 Transcription of Crp 2 14 0.70 9.91 2.61
56 INT24997 Protein_catabolism of Anpep 1 6 0.96 0 2.34
57 INT97134 Negative_regulation of CD80 1 8 0.57 5.09 2.11
58 INT123530 Phosphorylation of RELA 1 9 0.80 3.46 1.99
59 INT81328 Gene_expression of sar 1 7 0.66 2.86 1.85
60 INT165446 Positive_regulation of Phosphorylation of NFKB1 1 3 0.56 1.88 1.66
61 INT42959 Negative_regulation of Vom2r2 1 3 0.06 0.56 1.43
62 INT99639 Regulation of Phosphorylation of Trib3 1 6 0.14 0.44 1.36
63 INT135483 Protein_catabolism of Em 1 3 0.56 0.14 1.21
64 INT143714 Phosphorylation of Nfkbia 1 4 0.64 2.94 0.87
65 INT143720 Negative_regulation of Phosphorylation of Nfkbia 1 3 0.33 2.68 0.83
66 INT113893 Protein_catabolism of Dpp4 1 3 0.57 0.69 0.7
67 INT143719 Negative_regulation of Gene_expression of Nfkbia 1 2 0.43 1.31 0.68
68 INT106382 Gene_expression of NME1 2 13 0.66 5.18 0.56
69 INT150511 Negative_regulation of Me1 2 1 0.59 0.47 0.48
70 INT82967 Negative_regulation of Transcription of Crp 1 3 0.49 0.88 0.47
71 INT167167 Phosphorylation of Crp 1 1 0.52 0.39 0.36
72 INT150512 Regulation of Me1 1 1 0.45 0.26 0.26
73 INT150510 Positive_regulation of Gene_expression of Me1 1 1 0.50 0.2 0.21
74 INT150513 Gene_expression of Me1 1 1 0.78 0.2 0.21
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