J:Basic Res Cardiol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT317566 Car2 Positive_regulation of Camk2a 2 1 0.19 0.58 0.32
2 INT352945 Fig4 Regulation of Negative_regulation of Pik3cb 1 2 0.03 0.38 0.19
3 INT352943 Pik3cb Positive_regulation of Pdk1 1 1 0.09 0.21 0.06
4 INT352942 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 1 0.33 0.21 0.06
5 INT352941 Pik3cb Positive_regulation of Positive_regulation of Pdpk1 1 1 0.01 0.21 0.06
6 INT352944 Sh2d6 Negative_regulation of Phosphorylation of Akt1 1 1 0.06 0.08 0.04
7 INT317395 Gopc Regulation of Gene_expression of Car2 2 1 0.10 0 0.03
8 INT325600 Nppa Positive_regulation of Pde2a 1 1 0.11 0.16 0.03
9 INT325586 Nppa Positive_regulation of Prkg1 1 1 0.28 0.16 0.03
10 INT325591 Olfml3 Positive_regulation of Camk2a 1 1 0.01 0.26 0
11 INT325607 Positive_regulation of Gopc Regulation of Ang 1 1 0.15 0.26 0
12 INT325602 Binding of Ang and Pde2a 1 1 0.07 0.15 0
13 INT325589 Nppa Regulation of Cacna1c 1 1 0.05 0 0
14 INT325596 Ly6 Positive_regulation of C6 1 1 0.04 0 0
15 INT325590 Gopc Regulation of Ang 1 1 0.13 0.25 0
16 INT325599 Pls1 Regulation of Rgs2 1 1 0.00 0 0
17 INT325595 Nppa Negative_regulation of Ang 1 1 0.25 0.46 0
18 INT325587 Binding of Ang and Nppa 1 2 0.21 0.24 0
19 INT325603 Pde2a Regulation of Rgs2 1 1 0.03 0 0
20 INT325594 Binding of Ang and Olfml3 1 1 0.01 0.1 0
21 INT325613 Pls1 Regulation of Pde2a 1 1 0.00 0 0
22 INT325606 Negative_regulation of Nppa Negative_regulation of Ang 1 1 0.25 0.46 0
23 INT325597 Nppa Regulation of Gopc 1 1 0.15 0 0
24 INT325605 Pls1 Regulation of Nppa 1 1 0.00 0 0
25 INT325593 Pde2a Positive_regulation of Negative_regulation of Nppa 1 1 0.11 0 0
26 INT325612 Rgs2 Regulation of Pde2a 1 1 0.10 0 0
27 INT325598 Ang Positive_regulation of Camk2a 1 1 0.21 0.29 0
28 INT325588 Nppa Regulation of Localization of Rgs2 1 1 0.32 0 0
29 INT325585 Ly6 Positive_regulation of Trpc3 1 1 0.06 0 0
30 INT325609 Pde2a Positive_regulation of Gene_expression of Rgs2 1 1 0.12 0 0
31 INT325604 Nppa Regulation of Car2 1 3 0.23 0 0
32 INT325584 Binding of Olfml3 and Nppa 1 1 0.01 0.1 0
33 INT325601 Ang Positive_regulation of Phosphorylation of Camk2a 1 1 0.21 0.29 0
34 INT325608 Rgs2 Regulation of Pls1 1 1 0.00 0 0
35 INT325672 Wnt2 Positive_regulation of Gopc 1 1 0.01 0.58 0
36 INT325611 Nppa Regulation of Gene_expression of Car2 1 1 0.20 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9131 Positive_regulation of Prkcg 1 431 0.70 130.8 302.41
2 INT63932 Positive_regulation of Ephb1 7 537 0.70 259.67 296.14
3 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
4 INT4740 Gene_expression of Th 3 298 0.78 61.27 154.03
5 INT120811 Gene_expression of Gopc 4 1174 0.59 428.49 150.55
6 INT1033 Positive_regulation of Ca2 3 507 0.68 131.76 147.64
7 INT218 Positive_regulation of Th 5 245 0.70 40.5 120.1
8 INT170025 Gene_expression of Fig4 1 588 0.67 183.27 113.32
9 INT52651 Positive_regulation of Prkaca 1 136 0.67 40.82 99.16
10 INT52651 Positive_regulation of Prkaca 2 136 0.67 40.82 99.16
11 INT3537 Positive_regulation of Car2 10 413 0.56 103.51 94.35
12 INT12763 Phosphorylation of Prkcg 1 167 0.82 38.91 89.63
13 INT2520 Negative_regulation of Ca2 1 271 0.57 72.13 83.71
14 INT16654 Gene_expression of Insrr 1 138 0.46 58.96 75.68
15 INT49111 Negative_regulation of Prkaca 1 102 0.59 27.44 71.77
16 INT171145 Positive_regulation of Fig4 1 274 0.59 93.55 69.81
17 INT55344 Gene_expression of Ros1 1 396 0.54 217.64 59.98
18 INT169926 Positive_regulation of Gopc 3 416 0.46 157.8 58.67
19 INT31186 Negative_regulation of Insrr 1 81 0.37 24.91 55.94
20 INT119528 Positive_regulation of Camk2a 4 135 0.70 26.13 54.7
21 INT117713 Phosphorylation of Akt1 1 275 0.82 95.82 54.34
22 INT117713 Phosphorylation of Akt1 22 275 0.82 95.82 54.34
23 INT1032 Regulation of Ca2 4 202 0.52 54.91 53.03
24 INT48920 Negative_regulation of Ephb1 1 107 0.57 43.6 51.02
25 INT1232 Positive_regulation of Pdpk1 1 78 0.42 24.33 50.17
26 INT40777 Positive_regulation of Akt1 5 163 0.69 59.41 49.43
27 INT30170 Gene_expression of Car2 4 330 0.66 77.26 46.76
28 INT49552 Negative_regulation of Positive_regulation of Casp3 1 76 0.55 36.04 44.78
29 INT17561 Localization of Car2 1 303 0.79 60.95 44.52
30 INT170054 Negative_regulation of Gopc 1 280 0.38 117.89 42.4
31 INT48929 Regulation of Ephb1 2 71 0.62 24.42 42.11
32 INT65245 Gene_expression of Nos3 1 121 0.78 98.14 41.56
33 INT18992 Negative_regulation of Pdpk1 1 53 0.42 19.02 40.95
34 INT173693 Localization of Gopc 1 249 0.65 70.49 38.81
35 INT115649 Gene_expression of Camk2a 4 95 0.78 33.22 38
36 INT114729 Phosphorylation of Camk2a 7 110 0.82 15.49 33.19
37 INT89055 Phosphorylation of Prkaca 12 60 0.61 13.41 32.49
38 INT6558 Positive_regulation of Gene_expression of Th 3 56 0.70 9.64 30.89
39 INT72375 Phosphorylation of Mapk3 1 87 0.80 43.66 30.27
40 INT112707 Negative_regulation of Akt1 4 89 0.59 28.85 27.76
41 INT68758 Positive_regulation of Ros1 3 125 0.46 82.72 25.27
42 INT172458 Regulation of Gopc 1 155 0.53 62.57 24.86
43 INT96904 Regulation of Prkaca 2 33 0.44 10.86 24.51
44 INT96904 Regulation of Prkaca 1 33 0.44 10.86 24.51
45 INT40776 Gene_expression of Akt1 4 99 0.77 34.91 24.39
46 INT117718 Positive_regulation of Phosphorylation of Akt1 8 112 0.69 39.26 24.09
47 INT26719 Negative_regulation of Gene_expression of Th 1 38 0.58 11.87 22.78
48 INT17962 Regulation of Car2 1 124 0.41 33.98 22.71
49 INT23564 Negative_regulation of Car2 2 103 0.50 27.28 21.86
50 INT13643 Phosphorylation of Th 7 20 0.82 1.9 20.97
51 INT72060 Positive_regulation of Gene_expression of Ros1 1 127 0.41 76.76 20.91
52 INT89805 Gene_expression of Prkaca 1 45 0.77 11.03 20.77
53 INT170051 Positive_regulation of Gene_expression of Gopc 1 150 0.43 56.75 16.93
54 INT120966 Positive_regulation of Pik3cb 1 34 0.68 15.15 16.59
55 INT115650 Positive_regulation of Gene_expression of Camk2a 1 37 0.70 17.68 15.73
56 INT94573 Negative_regulation of Pik3cb 4 42 0.50 15.83 15.4
57 INT85964 Gene_expression of Pecam1 20 109 0.78 69.73 15.21
58 INT36263 Positive_regulation of CEL 1 53 0.69 34.88 12.87
59 INT121242 Positive_regulation of Gene_expression of Nos3 1 37 0.69 31.96 12.71
60 INT31368 Positive_regulation of Positive_regulation of Th 1 19 0.51 2.2 12.68
61 INT107875 Phosphorylation of Stat3 2 49 0.80 13.18 12.66
62 INT96924 Positive_regulation of Hspg2 1 40 0.49 14.5 12.32
63 INT26534 Regulation of Akt1 1 34 0.61 14.47 11.86
64 INT398 Localization of AGT 1 45 0.78 16.97 11.54
65 INT173272 Phosphorylation of Fig4 4 45 0.48 13.85 11.42
66 INT9550 Gene_expression of TNNI3 2 113 0.78 86.79 10.56
67 INT104441 Binding of NOVA2 1 72 0.42 16.41 10.51
68 INT29967 Positive_regulation of Positive_regulation of Car2 1 40 0.40 8.03 10.13
69 INT178306 Negative_regulation of Gene_expression of Gopc 1 71 0.37 26.43 9.74
70 INT120967 Negative_regulation of Phosphorylation of Akt1 1 47 0.57 23.67 8.98
71 INT119529 Positive_regulation of Phosphorylation of Camk2a 3 16 0.60 1.49 8.94
72 INT55342 Negative_regulation of Gene_expression of Ros1 1 49 0.37 31.62 8.93
73 INT6019 Positive_regulation of NEUROD1 1 37 0.67 17.3 8.89
74 INT170504 Positive_regulation of Gene_expression of Car2 1 60 0.41 19.1 8.45
75 INT102351 Regulation of Pecam1 1 7 0.61 22.45 7.58
76 INT85968 Positive_regulation of Pecam1 8 19 0.69 29.04 7.5
77 INT89052 Positive_regulation of Phosphorylation of Prkaca 3 13 0.37 2.92 7.05
78 INT76120 Gene_expression of Ptprc 6 102 0.59 30.42 7.02
79 INT76197 Positive_regulation of ADORA1 2 7 0.59 5.06 7
80 INT71824 Phosphorylation of Pdpk1 1 14 0.38 4.9 6.86
81 INT90645 Positive_regulation of Camk2g 1 16 0.70 2.03 6.66
82 INT92916 Gene_expression of Acta2 1 50 0.74 17.52 6.11
83 INT16923 Positive_regulation of Tnni3 1 32 0.50 25.01 5.44
84 INT188852 Gene_expression of Pde2a 14 13 0.19 6.44 5.35
85 INT186063 Phosphorylation of SOAT1 1 29 0.28 11.77 5.34
86 INT74051 Negative_regulation of Localization of Car2 1 27 0.38 9.58 5.1
87 INT124375 Gene_expression of Wnt2 9 67 0.56 38.03 4.67
88 INT74447 Gene_expression of Vwf 1 39 0.76 21.96 4.66
89 INT132224 Negative_regulation of Sh2d6 1 6 0.12 2.65 4.35
90 INT73434 Negative_regulation of Nppa 3 8 0.35 3.86 4.31
91 INT30165 Positive_regulation of Phosphorylation of Th 2 8 0.56 0.75 4.22
92 INT116643 Phosphorylation of Pik3cb 1 12 0.80 4.73 3.87
93 INT174277 Positive_regulation of Positive_regulation of Gopc 1 23 0.33 8.08 3.73
94 INT130351 Positive_regulation of Vwf 2 18 0.59 5.99 3.48
95 INT122997 Phosphorylation of Rps6kb1 1 46 0.72 9.92 3.43
96 INT116645 Regulation of Pik3cb 1 11 0.41 3.78 3.43
97 INT144522 Gene_expression of Trpc3 1 27 0.76 3.31 3.37
98 INT30166 Regulation of Phosphorylation of Th 2 4 0.50 0.52 3.33
99 INT188047 Positive_regulation of Wnt2 12 51 0.58 31.41 2.94
100 INT37734 Positive_regulation of Ang 1 18 0.46 9.17 2.87
101 INT2042 Phosphorylation of Ca2 7 21 0.55 1.54 2.81
102 INT99104 Gene_expression of Npr1 1 5 0.78 3.31 2.8
103 INT117715 Regulation of Phosphorylation of Akt1 1 15 0.51 3.23 2.78
104 INT13644 Negative_regulation of Phosphorylation of Th 1 2 0.43 0.06 2.51
105 INT81247 Gene_expression of Tnnt2 1 9 0.31 2.06 2.37
106 INT231557 Positive_regulation of Phosphorylation of SOAT1 1 7 0.22 5.22 2.33
107 INT42140 Gene_expression of Myo1f 1 7 0.19 2.45 2.27
108 INT70789 Negative_regulation of Agtrap 1 26 0.48 16.39 2.18
109 INT103179 Regulation of Phosphorylation of Prkaca 1 6 0.45 0.79 2.15
110 INT37733 Negative_regulation of Ang 3 11 0.41 3.23 2.09
111 INT156093 Negative_regulation of Positive_regulation of Ros1 1 8 0.23 5.17 2.03
112 INT32558 Negative_regulation of ADORA1 1 5 0.12 2.77 1.86
113 INT42065 Phosphorylation of Myo1f 1 13 0.38 2.05 1.71
114 INT196873 Positive_regulation of Ly6 1 5 0.07 1.74 1.66
115 INT67708 Binding of Pecam1 1 9 0.32 3.12 1.58
116 INT77383 Gene_expression of Tnni3 1 8 0.65 4.14 1.55
117 INT188855 Positive_regulation of Gene_expression of Pde2a 4 5 0.12 1.97 1.53
118 INT44164 Localization of Ren1 2 18 0.49 10.53 1.49
119 INT65452 Negative_regulation of Cacna1c 2 8 0.09 0.8 1.44
120 INT181809 Gene_expression of Atxn1 9 81 0.77 28.66 1.42
121 INT262545 Positive_regulation of Positive_regulation of Hspg2 1 4 0.49 1.39 1.41
122 INT73432 Gene_expression of Nppa 3 32 0.59 21.04 1.39
123 INT85967 Positive_regulation of Gene_expression of Pecam1 1 6 0.50 6.22 1.39
124 INT75183 Negative_regulation of TNNI3 1 19 0.53 9.34 1.32
125 INT65324 Gene_expression of Tnni3 3 12 0.66 7.97 1.25
126 INT126813 Positive_regulation of Trpc3 1 4 0.67 0 1.23
127 INT151513 Negative_regulation of Gene_expression of Pecam1 1 8 0.37 4.73 1.22
128 INT47644 Positive_regulation of Localization of AGT 1 4 0.45 1.24 1.2
129 INT49536 Regulation of Regulation of Ca2 1 6 0.38 3.89 1.13
130 INT96861 Binding of Ang 2 11 0.32 4.46 1.1
131 INT128412 Positive_regulation of Cand1 1 5 0.67 3.58 1.1
132 INT66452 Positive_regulation of Cacna1c 3 6 0.19 2.56 1.08
133 INT87637 Localization of Ang 3 11 0.63 4.42 1.03
134 INT89853 Gene_expression of Srgn 2 12 0.44 1.13 1
135 INT124374 Binding of Wnt2 1 21 0.31 10.16 0.99
136 INT240463 Negative_regulation of Phosphorylation of Prkaca 1 2 0.23 0.59 0.99
137 INT51270 Positive_regulation of Camk2d 1 3 0.19 1.49 0.92
138 INT38172 Regulation of Ang 5 8 0.31 4.13 0.9
139 INT84571 Gene_expression of Rgs2 6 6 0.67 3.18 0.89
140 INT242152 Transcription of Wnt2 1 8 0.57 5.22 0.88
141 INT287841 Positive_regulation of Phosphorylation of Ca2 1 2 0.18 0.58 0.75
142 INT68650 Negative_regulation of Tnni3 1 8 0.37 1.01 0.73
143 INT320992 Positive_regulation of Positive_regulation of Pecam1 2 5 0.50 4.23 0.73
144 INT16132 Positive_regulation of C6 1 4 0.23 0.34 0.73
145 INT84570 Positive_regulation of Gene_expression of Rgs2 3 3 0.50 0.67 0.67
146 INT166132 Positive_regulation of Dhrs4 1 2 0.54 1.95 0.65
147 INT161821 Phosphorylation of Myl2 27 3 0.34 1.15 0.62
148 INT109081 Localization of Nppa 3 9 0.59 2.72 0.61
149 INT124373 Positive_regulation of Gene_expression of Wnt2 3 14 0.42 8.28 0.6
150 INT213503 Regulation of Wnt2 2 9 0.37 3.54 0.56
151 INT287853 Phosphorylation of Tnni3 31 1 0.63 0.87 0.56
152 INT321314 Positive_regulation of Pdk1 1 3 0.22 0.74 0.55
153 INT120961 Positive_regulation of Phosphorylation of Pik3cb 1 3 0.26 1.02 0.53
154 INT183375 Binding of Nppa 2 14 0.38 8.95 0.51
155 INT58938 Gene_expression of C6 1 10 0.33 0.97 0.5
156 INT19315 Phosphorylation of Nppb 1 2 0.55 0.23 0.47
157 INT201524 Localization of Wnt2 3 14 0.62 9.24 0.46
158 INT187466 Localization of Pecam1 1 6 0.47 1.65 0.46
159 INT65323 Positive_regulation of Positive_regulation of Tnni3 1 5 0.36 1.93 0.46
160 INT35501 Positive_regulation of Myo1f 2 5 0.69 1.73 0.39
161 INT140194 Negative_regulation of Ppp1ca 1 3 0.16 0.42 0.38
162 INT287838 Phosphorylation of Cand1 18 1 0.80 0.64 0.29
163 INT270233 Phosphorylation of Camk2d 2 2 0.33 0.54 0.28
164 INT287858 Phosphorylation of Mlc1 7 1 0.20 0 0.26
165 INT187465 Localization of Ptprc 1 8 0.62 3.71 0.25
166 INT214664 Gene_expression of Serpina5 1 6 0.26 2.91 0.22
167 INT325579 Phosphorylation of Rgs2 1 2 0.55 0.06 0.2
168 INT240712 Negative_regulation of Negative_regulation of Ca2 1 4 0.36 0.38 0.19
169 INT161173 Negative_regulation of Localization of Ang 2 3 0.39 2.19 0.18
170 INT183377 Positive_regulation of Nppa 3 7 0.38 1.46 0.16
171 INT181807 Positive_regulation of Atxn1 2 12 0.34 3.96 0.15
172 INT181813 Negative_regulation of Gene_expression of Atxn1 1 9 0.42 3.47 0.15
173 INT186164 Phosphorylation of NOVA2 1 3 0.07 0.87 0.15
174 INT153077 Positive_regulation of Gene_expression of Nppa 2 9 0.40 5.07 0.13
175 INT210032 Binding of Serpina5 1 4 0.18 1.87 0.12
176 INT172815 Gene_expression of Cand1 2 4 0.65 1.86 0.12
177 INT287862 Phosphorylation of Tnnt2 9 1 0.42 0.07 0.12
178 INT287860 Regulation of Phosphorylation of Tnni3 3 1 0.21 0.16 0.12
179 INT287852 Positive_regulation of Phosphorylation of Myl2 9 1 0.29 0.16 0.12
180 INT287850 Positive_regulation of Phosphorylation of Tnni3 6 1 0.54 0.09 0.11
181 INT149211 Regulation of Gene_expression of Trpc3 1 2 0.60 0 0.1
182 INT161819 Positive_regulation of Myl2 1 2 0.29 0.34 0.1
183 INT232589 Positive_regulation of Serpina5 1 4 0.19 0.8 0.09
184 INT168853 Binding of Tnnt2 1 2 0.19 0.4 0.08
185 INT287839 Positive_regulation of Phosphorylation of Camk2d 3 1 0.07 0.08 0.08
186 INT287836 Phosphorylation of Mylk2 1 1 0.22 0 0.08
187 INT352938 Phosphorylation of Sh2d6 1 1 0.10 0.17 0.08
188 INT287859 Positive_regulation of Phosphorylation of Mlc1 2 1 0.17 0 0.08
189 INT287849 Positive_regulation of Phosphorylation of Cand1 2 1 0.49 0.07 0.08
190 INT287840 Regulation of Phosphorylation of Mlc1 1 1 0.11 0 0.08
191 INT325569 Binding of Rgs2 1 2 0.30 0.19 0.07
192 INT287845 Phosphorylation of Ttn 2 1 0.18 0.19 0.07
193 INT325665 Positive_regulation of Axin2 2 1 0.36 0.59 0.06
194 INT242136 Gene_expression of Sfrp1 1 3 0.46 2.75 0.05
195 INT325560 Positive_regulation of Negative_regulation of Car2 1 2 0.25 0 0.05
196 INT290420 Negative_regulation of Positive_regulation of Nppa 1 2 0.32 0.37 0.05
197 INT242146 Positive_regulation of Gene_expression of Sfrp1 1 2 0.30 1.68 0.05
198 INT308505 Negative_regulation of Sacs 1 1 0.05 0.09 0.05
199 INT325564 Positive_regulation of Positive_regulation of Nppa 2 1 0.38 0.08 0.05
200 INT287843 Regulation of Phosphorylation of Myl2 2 1 0.16 0.09 0.05
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