J:Behav. Brain Res.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT135035 Binding of Hk1 and Tac1 1 2 0.35 0.18 2.14
2 INT90929 Binding of Ap1m1 and Insrr 1 1 0.01 0.19 1.6
3 INT93435 Binding of Casp3 and Cckbr 1 1 0.06 0.15 1.18
4 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 1 0.22 0.26 1.12
5 INT142413 Oprm1 Positive_regulation of Gdnf 1 1 0.19 0.29 1.09
6 INT93234 Negative_regulation of Pde4b Negative_regulation of Gene_expression of Fos 1 1 0.41 0.1 0.96
7 INT139594 Binding of Nts and Rbm39 1 1 0.02 0.19 0.87
8 INT139592 Ntsr1 Positive_regulation of Nts 1 1 0.09 0.17 0.79
9 INT139593 Ntsr1 Positive_regulation of Rbm39 1 1 0.01 0.17 0.79
10 INT138938 Agrp Regulation of Pmch 1 1 0.35 0.1 0.38
11 INT137308 sps Negative_regulation of Cstb 1 1 0.03 1.59 0.31

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 10 3083 0.78 894.43 1639.02
2 INT796 Gene_expression of Penk 1 1902 0.78 275.47 1057.59
3 INT3439 Localization of Abat 6 1017 0.78 112.39 727.06
4 INT5202 Positive_regulation of Gene_expression of Fos 7 1163 0.70 319.28 684
5 INT292 Localization of Penk 1 876 0.81 88.44 669.14
6 INT728 Positive_regulation of Penk 2 1068 0.70 186.9 636.87
7 INT797 Regulation of Penk 5 812 0.62 111.13 542.24
8 INT5228 Positive_regulation of Fos 3 934 0.70 209.8 503.87
9 INT5895 Gene_expression of Oprm1 3 525 0.78 120.67 407.29
10 INT1395 Negative_regulation of Penk 3 537 0.59 87.33 389.81
11 INT6056 Negative_regulation of Gene_expression of Fos 2 601 0.59 193.05 386.84
12 INT6580 Negative_regulation of Ptgs1 1 929 0.59 381.53 376.26
13 INT5660 Binding of Oprd1 1 477 0.48 71.86 342.06
14 INT5979 Gene_expression of Oprd1 1 428 0.78 75.64 320.32
15 INT5540 Positive_regulation of Oprm1 3 344 0.70 76.77 319.71
16 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
17 INT738 Regulation of POMC 2 459 0.62 111.19 243.74
18 INT9987 Gene_expression of Abat 1 296 0.78 95.46 226.34
19 INT1212 Binding of Oprl1 1 312 0.48 28.6 225.15
20 INT95787 Positive_regulation of Mapk1 1 568 0.70 226.51 220.94
21 INT48955 Gene_expression of Nos2 2 753 0.78 403.87 208.08
22 INT2211 Negative_regulation of Abat 1 267 0.59 66.51 200.98
23 INT4803 Transcription of Penk 1 435 0.72 59.09 182.4
24 INT7506 Negative_regulation of Ltp 2 267 0.46 91.01 176.8
25 INT26472 Regulation of Oprm1 2 191 0.62 35.84 173.1
26 INT4937 Negative_regulation of Oprd1 1 224 0.59 44.51 171.11
27 INT48953 Positive_regulation of Nos2 3 486 0.70 239.85 131.87
28 INT5380 Positive_regulation of Gene_expression of Fos 7 243 0.70 105.65 131.05
29 INT65600 Positive_regulation of Casp3 4 376 0.70 198.44 128.03
30 INT5931 Regulation of Oprm1 2 149 0.62 18.15 125.93
31 INT6323 Positive_regulation of Gabrg1 1 213 0.70 45.08 124.34
32 INT7533 Gene_expression of Tlr4 1 720 0.78 343.22 121.57
33 INT5283 Positive_regulation of Npy 1 191 0.70 66.77 109.2
34 INT7944 Positive_regulation of Fos 12 193 0.70 60.69 98.31
35 INT3537 Positive_regulation of Car2 1 413 0.56 103.51 94.35
36 INT9516 Negative_regulation of Gabrg1 1 149 0.53 27.83 91.02
37 INT1160 Positive_regulation of Rbm39 2 122 0.57 28.19 90.28
38 INT6214 Negative_regulation of Adarb1 1 123 0.50 26.39 89.57
39 INT3441 Regulation of Localization of Abat 1 117 0.38 8.67 87.59
40 INT5610 Positive_regulation of Insr 4 140 0.69 37.26 86.24
41 INT4798 Gene_expression of Nts 1 169 0.77 29.56 86.04
42 INT82448 Gene_expression of S100a8 1 246 0.77 236.72 84.02
43 INT92434 Phosphorylation of Mapk1 2 287 0.82 91.65 83.46
44 INT64636 Positive_regulation of Gene_expression of Nos2 4 242 0.70 147.52 79.53
45 INT9382 Regulation of TRPV1 1 149 0.62 53.99 77.46
46 INT15769 Gene_expression of Il1b 2 146 0.78 114.51 75.35
47 INT7028 Localization of Pdyn 1 90 0.81 8.89 73.54
48 INT31774 Positive_regulation of Vta1 2 67 0.44 14.52 71.79
49 INT5852 Gene_expression of Penk 3 167 0.78 44.44 71.13
50 INT13276 Regulation of Ltp 2 107 0.53 30.78 69.13
51 INT6489 Positive_regulation of Gene_expression of Tnf 1 140 0.70 92.31 67.85
52 INT6176 Positive_regulation of Htr1a 1 117 0.67 28.23 66.17
53 INT1425 Gene_expression of Rbm39 1 143 0.58 51.32 65.44
54 INT1951 Positive_regulation of Tlr4 4 345 0.70 176.99 62.42
55 INT1169 Negative_regulation of Bche 3 322 0.59 149.22 61.27
56 INT11318 Gene_expression of Gtf3a 2 274 0.52 183.82 60.89
57 INT7032 Positive_regulation of Pdyn 1 94 0.66 26.51 58.83
58 INT8732 Positive_regulation of Gene_expression of Oprm1 2 76 0.70 22.59 58.83
59 INT31116 Gene_expression of Casp3 2 192 0.78 78.21 57.43
60 INT5770 Binding of Rbm39 1 88 0.41 13.23 55.5
61 INT1486 Negative_regulation of Cpe 2 85 0.59 28.78 54.08
62 INT49747 Transcription of Oprm1 1 68 0.72 9.01 53.78
63 INT48642 Positive_regulation of TCEA1 1 92 0.70 24.59 53.64
64 INT48952 Negative_regulation of Nos2 1 204 0.59 101.73 53.15
65 INT5957 Positive_regulation of Cpe 1 65 0.69 21.07 51.22
66 INT5136 Negative_regulation of PDYN 2 71 0.59 11.22 51.14
67 INT789 Positive_regulation of YY1 1 69 0.67 14.07 47.06
68 INT27493 Negative_regulation of Casp3 2 114 0.56 56.89 44.63
69 INT7828 Positive_regulation of Oprd1 1 55 0.69 14.11 42.86
70 INT4850 Binding of Tac1 1 57 0.47 14.25 42.17
71 INT48075 Positive_regulation of Il1b 1 71 0.67 48.63 40.48
72 INT92437 Positive_regulation of Phosphorylation of Mapk1 2 113 0.70 32.19 40.29
73 INT18893 Positive_regulation of CPP 2 81 0.69 38.03 34.33
74 INT34465 Regulation of Oprd1 1 34 0.45 7.14 34.29
75 INT81289 Positive_regulation of Gene_expression of Tlr4 1 192 0.69 104.5 33.89
76 INT7286 Regulation of Transcription of Penk 1 81 0.62 9.25 33.45
77 INT3117 Regulation of Oxt 1 103 0.61 17.93 32.28
78 INT45365 Negative_regulation of Cfp 2 68 0.57 25.44 32.11
79 INT48890 Gene_expression of Gdnf 2 91 0.77 28.62 31.49
80 INT11087 Positive_regulation of Drd2 1 54 0.69 12.4 31.43
81 INT11279 Positive_regulation of Penk 1 65 0.70 18.72 30.29
82 INT6660 Positive_regulation of Jun 1 148 0.69 67.58 29.73
83 INT12319 Positive_regulation of Cort 1 52 0.61 22.55 29.35
84 INT65597 Negative_regulation of Casp3 4 69 0.59 39.19 29.32
85 INT5300 Regulation of Insr 2 54 0.60 11.33 29.26
86 INT65598 Negative_regulation of Positive_regulation of Casp3 4 45 0.59 18.36 28.59
87 INT57692 Positive_regulation of Gene_expression of Il1b 1 50 0.67 43.54 28.29
88 INT7717 Positive_regulation of Adra2a 1 62 0.70 17.68 27.32
89 INT17331 Positive_regulation of JUN 1 132 0.69 60.4 27.03
90 INT12681 Regulation of Trib3 1 76 0.53 23.92 26.58
91 INT5378 Regulation of Gene_expression of Fos 4 47 0.60 14.47 26.41
92 INT17925 Transcription of Npy 1 53 0.72 15.75 25.56
93 INT5851 Positive_regulation of Gene_expression of Penk 2 52 0.70 14.57 25.05
94 INT57192 Binding of Ltp 1 43 0.41 17.48 24.96
95 INT22549 Positive_regulation of Positive_regulation of Casp3 3 48 0.56 29.5 23.7
96 INT51029 Negative_regulation of Il1b 1 34 0.57 29.34 23.62
97 INT18894 Gene_expression of CPP 1 44 0.77 23.05 23.05
98 INT6270 Binding of HTR1D 2 55 0.47 9.54 22.86
99 INT29704 Regulation of Casp3 3 51 0.56 22.13 22.79
100 INT8048 Gene_expression of Nts 2 45 0.74 8.9 21.84
101 INT5586 Binding of Fos 1 47 0.48 12.7 21.33
102 INT7039 Regulation of Nkx1-1 1 22 0.44 10.51 20.89
103 INT12031 Negative_regulation of Car1 1 44 0.59 20.46 19.36
104 INT11524 Negative_regulation of Gabrd 1 39 0.58 6.25 18.8
105 INT12269 Gene_expression of Chrna9 1 39 0.73 6.98 18.44
106 INT11275 Regulation of Fos 1 37 0.60 5.79 18.18
107 INT12360 Regulation of Tac1 1 31 0.61 5.9 18
108 INT8526 Negative_regulation of Positive_regulation of Fos 3 26 0.59 5.99 17.52
109 INT9358 Positive_regulation of HTR1B 1 26 0.67 11 17.51
110 INT75585 Negative_regulation of Negative_regulation of Ltp 1 18 0.37 9.81 16.63
111 INT2480 Negative_regulation of Got1 1 43 0.51 14.47 16.09
112 INT4616 Regulation of Maoa 3 40 0.62 6.09 15.94
113 INT47742 Binding of Flvcr2 1 26 0.42 3.28 15.87
114 INT111462 Negative_regulation of Phosphorylation of Mapk1 2 45 0.57 19.49 15.59
115 INT8391 Positive_regulation of Gene_expression of Nts 1 23 0.67 5.05 14.59
116 INT11762 Regulation of Dbi 2 40 0.62 7.83 14.48
117 INT20071 Positive_regulation of HTR2A 1 33 0.67 10.89 14
118 INT35120 Gene_expression of Sdcbp 1 68 0.67 21.33 13.96
119 INT22272 Negative_regulation of HTR2A 2 28 0.57 7.62 13.87
120 INT102897 Positive_regulation of Gene_expression of Gdnf 1 34 0.69 11.13 13.28
121 INT7465 Negative_regulation of Mbp 1 53 0.58 19.12 13.27
122 INT58852 Positive_regulation of Enc1 1 20 0.49 7.51 13.25
123 INT123593 Gene_expression of Snca 5 58 0.78 35.76 12.87
124 INT119396 Regulation of Positive_regulation of Mapk1 1 22 0.61 7.88 12.25
125 INT110988 Gene_expression of Insr 2 58 0.42 42.12 12.18
126 INT15756 Positive_regulation of Gene_expression of Jun 1 29 0.69 16.58 12.06
127 INT7389 Positive_regulation of Localization of Pdyn 1 15 0.48 1.68 11.88
128 INT89181 Gene_expression of Mc3r 2 33 0.77 22.48 11.85
129 INT119400 Phosphorylation of Car2 1 19 0.52 8.47 11.63
130 INT105754 Regulation of St13 2 8 0.28 0.75 11.41
131 INT82950 Positive_regulation of Gdnf 1 36 0.51 11.72 10.5
132 INT5791 Positive_regulation of Positive_regulation of Rbm39 1 13 0.25 1.61 9.88
133 INT29802 Localization of Rbm39 1 18 0.64 4.04 9.84
134 INT113734 Gene_expression of Agrp 4 31 0.77 11.04 9.02
135 INT15768 Gene_expression of Il1a 2 20 0.71 9.31 8.78
136 INT64815 Binding of Jun 3 49 0.48 21.47 8.59
137 INT23104 Positive_regulation of Cga 1 20 0.70 10.35 8.03
138 INT59333 Positive_regulation of Chrna9 2 14 0.64 3.23 7.64
139 INT18393 Negative_regulation of Ryr1 1 15 0.43 3.63 7.57
140 INT10145 Gene_expression of Plg 2 28 0.62 12.68 7.46
141 INT22794 Regulation of Gt(pU21)50Imeg 1 4 0.02 0.14 7.45
142 INT89309 Negative_regulation of Pde4b 2 21 0.53 12.81 7.32
143 INT36405 Positive_regulation of Insr 2 26 0.66 24.5 7.24
144 INT53491 Negative_regulation of Jun 2 28 0.57 14.2 6.9
145 INT71116 Gene_expression of Plau 6 29 0.77 4.94 6.45
146 INT40962 Localization of Avp 1 40 0.80 20.5 6.38
147 INT4863 Positive_regulation of ap 1 22 0.37 9.13 6.11
148 INT17779 Negative_regulation of Got1 1 12 0.40 3.5 6.08
149 INT52311 Positive_regulation of JUNB 7 12 0.40 4.48 6.02
150 INT9567 Binding of Nts 1 10 0.44 2.14 5.89
151 INT37834 Negative_regulation of Positive_regulation of CPP 1 14 0.58 6.22 5.69
152 INT88784 Negative_regulation of stm 7 11 0.56 0.51 5.33
153 INT19641 Negative_regulation of Gene_expression of Penk 2 11 0.58 1.12 4.91
154 INT20676 Gene_expression of Ctse 1 16 0.77 10.59 4.68
155 INT59331 Positive_regulation of Gene_expression of Chrna9 1 6 0.62 1.91 4.63
156 INT23035 Regulation of Il1a 1 6 0.60 5.69 4.25
157 INT15462 Negative_regulation of Il1a 3 4 0.59 4.68 4.17
158 INT110348 Negative_regulation of Dpp4 2 28 0.46 22.39 4.12
159 INT64163 Negative_regulation of Gene_expression of Jun 1 13 0.58 3.86 4.03
160 INT60789 Negative_regulation of Chrna9 1 9 0.34 0.91 3.95
161 INT59674 Gene_expression of Chrna6 1 8 0.47 2.12 3.94
162 INT6661 Positive_regulation of Positive_regulation of Jun 1 31 0.50 7.12 3.89
163 INT113924 Binding of Mapk1 1 27 0.38 8.64 3.84
164 INT123988 Regulation of Agrp 2 11 0.60 5.92 3.82
165 INT64817 Positive_regulation of Binding of Jun 1 16 0.69 6.78 3.81
166 INT86769 Positive_regulation of Gene_expression of Rbm39 1 11 0.25 5.6 3.8
167 INT124736 Positive_regulation of Gene_expression of Insr 2 6 0.31 7.55 3.12
168 INT71117 Positive_regulation of Gene_expression of Plau 5 9 0.69 0.22 2.92
169 INT48688 Positive_regulation of HTR4 1 12 0.67 1.94 2.81
170 INT70377 Regulation of Transcription of Oprm1 1 3 0.47 0.93 2.78
171 INT119399 Phosphorylation of Camk2n2 1 3 0.25 0.53 2.73
172 INT143684 Negative_regulation of Fosb 1 4 0.43 2.37 2.72
173 INT16025 Gene_expression of Lth1 2 6 0.40 1.89 2.5
174 INT32920 Gene_expression of Msx1 2 19 0.71 4.24 2.42
175 INT12456 Negative_regulation of Positive_regulation of Adra2a 1 4 0.37 1.35 2.42
176 INT141359 Negative_regulation of Mrgprc 2 1 0.34 0 2.4
177 INT23788 Negative_regulation of Kcne1 1 7 0.39 0.73 2.38
178 INT81063 Regulation of Inadl2 1 4 0.18 0.74 2.37
179 INT133681 Positive_regulation of Gene_expression of Mc3r 4 5 0.67 5.38 2.19
180 INT59673 Negative_regulation of Chrna6 2 8 0.30 2.31 2.16
181 INT48858 Gene_expression of Gmps 3 8 0.52 0.36 2.13
182 INT2138 Negative_regulation of Cga 1 5 0.43 3.37 2.1
183 INT65226 Regulation of NARG2 1 3 0.36 1.6 1.99
184 INT85827 Regulation of vs 2 16 0.36 4.58 1.98
185 INT88783 Positive_regulation of stm 1 4 0.39 0 1.98
186 INT86607 Negative_regulation of Ntsr1 1 3 0.43 1.75 1.98
187 INT59283 Positive_regulation of Gene_expression of Plg 1 6 0.25 2.36 1.97
188 INT18758 Positive_regulation of Gmps 1 4 0.41 0.36 1.86
189 INT115088 Negative_regulation of Enc1 1 4 0.36 2.33 1.85
190 INT35121 Negative_regulation of Gene_expression of Sdcbp 1 6 0.43 2.4 1.83
191 INT112576 Gene_expression of Casp14 1 5 0.75 3.1 1.83
192 INT3827 Gene_expression of Tfpi 1 5 0.53 0.36 1.81
193 INT73844 Positive_regulation of IGHM 1 3 0.24 0.28 1.76
194 INT30741 Regulation of Npepo 1 5 0.29 1.42 1.75
195 INT104093 Positive_regulation of Olah 1 4 0.39 1.45 1.71
196 INT48813 Negative_regulation of Plau 2 12 0.44 3.46 1.66
197 INT119401 Negative_regulation of Phosphorylation of Camk2n2 1 1 0.17 0.24 1.59
198 INT119402 Positive_regulation of Phosphorylation of Camk2n2 1 1 0.18 0.23 1.58
199 INT52312 Negative_regulation of Positive_regulation of JUNB 2 1 0.12 0.13 1.58
200 INT19342 Regulation of Insr 1 12 0.24 6.11 1.54
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