J:Biochem. Biophys. Res. Commun.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 2 0.76 8.19 6.66
2 INT20456 Binding of Pomc and Penk 9 2 0.41 0.26 3.93
3 INT61359 TNF Positive_regulation of NFKB1 11 1 0.63 6.66 3.89
4 INT132862 Ngf Positive_regulation of Bdnf 4 1 0.46 4.05 3.65
5 INT69665 Binding of Oprd1 and Pnoc 5 1 0.35 0.4 2.5
6 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 1 0.39 0.87 2.05
7 INT88883 IRF6 Positive_regulation of Nfkb1 1 2 0.11 0.53 2.01
8 INT69666 Binding of OPRL1 and Pnoc 2 1 0.45 0.06 1.66
9 INT134742 Binding of OPRM1 and SV2A 1 2 0.33 0.18 1.64
10 INT74937 IL1B Positive_regulation of CPOX 5 2 0.18 1.13 1.55
11 INT69788 Binding of Gpr1 and Pnoc 2 1 0.09 0 1.49
12 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 4 0.03 0.76 1.25
13 INT121362 Trpv1 Regulation of Localization of Ins1 1 2 0.51 0.17 1.12
14 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 3 0.58 0.72 1.09
15 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 1 0.02 0.27 1.03
16 INT88881 Negative_regulation of IRF6 Positive_regulation of Nfkb1 1 1 0.09 0.27 1.03
17 INT74934 Regulation of IRF6 Positive_regulation of Nfkb1 1 1 0.01 0.52 1.02
18 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 1 0.21 0.27 1.02
19 INT88874 Ifng Regulation of Nos2 1 1 0.01 0.26 1.01
20 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 1 0.10 0 1.01
21 INT74933 IRF6 Positive_regulation of Nfkb1 1 1 0.02 0.52 1.01
22 INT88879 Ifng Positive_regulation of Nfkb1 1 1 0.01 0.26 1.01
23 INT88884 IRF6 Regulation of Nos2 1 1 0.12 0.26 1
24 INT88886 IRF6 Positive_regulation of Nos2 1 1 0.22 0.26 1
25 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 1 0.20 0.26 1
26 INT143323 Binding of HLA-B and HP 1 1 0.04 0.95 0.93
27 INT78062 Il1a Positive_regulation of Localization of Il6 3 2 0.24 0.48 0.9
28 INT56274 RYBP Negative_regulation of Cyp2e1 1 1 0.01 0.17 0.9
29 INT56273 RYBP Negative_regulation of Cyp1a2 1 1 0.01 0.17 0.9
30 INT65011 IL1B Positive_regulation of PTGER2 4 1 0.08 0.92 0.82
31 INT56275 RYBP Positive_regulation of Negative_regulation of Cyp1a2 1 1 0.01 0.17 0.81
32 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 1 0.21 0.1 0.81
33 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 1 0.06 0.1 0.81
34 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 2 0.06 1.32 0.78
35 INT56272 Cyp2e1 Positive_regulation of Cyp1a2 1 1 0.52 0.17 0.77
36 INT4831 Binding of Trpv1 and Trpv1 1 1 0.03 0.08 0.72
37 INT4832 Negative_regulation of Binding of Trpv1 and Trpv1 1 1 0.04 0.08 0.72
38 INT74941 IL1B Positive_regulation of Gene_expression of PTGER2 1 2 0.08 0.48 0.72
39 INT82759 Binding of IGHG3 and OPRM1 2 1 0.06 0 0.7
40 INT61798 Binding of NDP and POMC 2 2 0.22 0 0.66
41 INT113962 OPRM1 Regulation of CREB1 1 1 0.39 0.31 0.6
42 INT145617 Ngf Positive_regulation of Gene_expression of Fez1 1 2 0.43 0.57 0.57
43 INT138928 Ifng Positive_regulation of Transcription of Cxcl9 1 2 0.31 0.65 0.51
44 INT102214 ENG Negative_regulation of HP 1 1 0.01 0 0.49
45 INT145435 Binding of CPOX and HMOX1 1 1 0.01 0.42 0.49
46 INT145433 Binding of CPOX and HMOX2 1 1 0.01 0.42 0.49
47 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 2 0.29 0.7 0.49
48 INT88889 Binding of HSPG2 and CALCRL 1 2 0.00 0 0.48
49 INT145434 Binding of HMOX1 and PTGS2 1 1 0.02 0.41 0.47
50 INT130137 TNF Positive_regulation of Positive_regulation of S100A10 1 1 0.07 0.62 0.47
51 INT145436 Binding of HMOX2 and PTGS2 1 1 0.02 0.41 0.47
52 INT102213 Binding of ENG and HP 1 1 0.01 0 0.47
53 INT81991 Bmpr2 Positive_regulation of Gene_expression of ODF1 1 3 0.03 1.59 0.41
54 INT61799 Negative_regulation of Binding of NDP and POMC 1 1 0.20 0 0.41
55 INT22524 Binding of CPB1 and CPA6 1 1 0.05 0 0.39
56 INT58535 Penk Negative_regulation of Protein_catabolism of Cck 1 1 0.30 0 0.38
57 INT34865 Ghrh Positive_regulation of Gene_expression of Gnrhr 1 1 0.07 0 0.37
58 INT58536 Nts Negative_regulation of Protein_catabolism of Cck 1 1 0.46 0 0.37
59 INT74938 Negative_regulation of IL1B Positive_regulation of PTGER2 1 1 0.07 0.23 0.36
60 INT32818 Binding of Pomc and Gtf3a 1 2 0.02 0 0.36
61 INT93202 Binding of IGHG3 and Oprm1 1 1 0.02 0 0.35
62 INT93201 Positive_regulation of Binding of IGHG3 and OPRM1 1 1 0.02 0 0.35
63 INT90544 Efw Negative_regulation of Regulation of Pnoc 1 1 0.00 0 0.34
64 INT90543 Npff Negative_regulation of Regulation of Pnoc 1 1 0.26 0 0.34
65 INT128076 POMC Positive_regulation of Gene_expression of TNF 1 1 0.33 0.31 0.33
66 INT78063 Il1a Positive_regulation of Il1b 1 1 0.02 0.07 0.32
67 INT78064 Cyp3a23/3a1 Regulation of Localization of Il6 1 1 0.08 0.07 0.32
68 INT93464 Hcrt Negative_regulation of Pomc 1 1 0.18 0 0.31
69 INT88904 Binding of SCT and Hcrt 1 1 0.07 0 0.31
70 INT88903 Regulation of Binding of SCT and Hcrt 1 1 0.06 0 0.31
71 INT93465 Hcrt Negative_regulation of Localization of Gnrh1 1 1 0.36 0 0.31
72 INT74940 HGF Positive_regulation of CPOX 1 1 0.13 0.25 0.3
73 INT74942 HGF Positive_regulation of PTGS1 1 1 0.11 0.25 0.29
74 INT62550 Il1f5 Regulation of Gene_expression of Icam1 1 1 0.05 0.44 0.28
75 INT126878 Binding of TRPV1 and RAB11FIP3 1 1 0.15 0.08 0.28
76 INT78065 Cyp3a23/3a1 Negative_regulation of Gene_expression of Il6 1 1 0.12 0.07 0.27
77 INT141315 Gs Regulation of Kcnk10 1 1 0.16 0.64 0.27
78 INT145616 Binding of Fez1 and Kif5a 1 1 0.05 0.25 0.27
79 INT78061 Cyp3a23/3a1 Negative_regulation of Localization of Il6 1 1 0.12 0.07 0.27
80 INT25946 Regulation of Binding of Penk and App 1 1 0.18 0.19 0.27
81 INT145618 Binding of Fez1 and Kif27 1 1 0.13 0.25 0.27
82 INT141314 Gs Regulation of Kcnk4 1 1 0.19 0.64 0.27
83 INT25944 Binding of Penk and App 1 1 0.15 0.19 0.27
84 INT78067 Tlr4 Positive_regulation of Localization of Ptger2 1 1 0.01 0.07 0.26
85 INT71309 Il1a Positive_regulation of Nos2 1 2 0.21 0.26 0.26
86 INT145619 Binding of Fez1 and LOC691920 1 1 0.03 0.27 0.26
87 INT62549 Il1b Regulation of Icam1 1 1 0.13 0.39 0.25
88 INT138925 Ifng Positive_regulation of Gene_expression of Cxcl9 1 1 0.25 0.32 0.25
89 INT62548 Il1b Regulation of Gene_expression of Icam1 1 1 0.22 0.39 0.25
90 INT80282 IL4 Positive_regulation of Gene_expression of CCL13 1 1 0.35 0.39 0.24
91 INT80288 IL1A Positive_regulation of CCL13 1 1 0.17 0.39 0.24
92 INT80281 TNF Positive_regulation of CCL7 1 1 0.09 0.39 0.24
93 INT80280 IL1A Positive_regulation of CCL7 1 1 0.19 0.39 0.24
94 INT80284 IL1A Positive_regulation of Gene_expression of CCL13 1 1 0.58 0.39 0.24
95 INT80293 TNF Positive_regulation of CCL13 1 1 0.09 0.39 0.24
96 INT80290 IL4 Positive_regulation of CCL7 1 1 0.11 0.39 0.24
97 INT80278 IFNG Positive_regulation of CCL13 1 1 0.12 0.39 0.24
98 INT80285 CCL7 Positive_regulation of Gene_expression of CCL13 1 1 0.15 0.39 0.24
99 INT138930 Ifng Positive_regulation of Cxcl9 1 1 0.43 0.29 0.24
100 INT80289 IFNG Positive_regulation of Gene_expression of CCL13 1 1 0.40 0.39 0.24
101 INT80291 IL4 Positive_regulation of CCL13 1 1 0.10 0.39 0.24
102 INT138924 Negative_regulation of Ifng Positive_regulation of Cxcl9 1 1 0.37 0.29 0.24
103 INT80283 TNF Positive_regulation of Gene_expression of CCL13 1 1 0.29 0.39 0.24
104 INT80277 IFNG Positive_regulation of CCL7 1 1 0.13 0.39 0.24
105 INT80292 IL4 Positive_regulation of Gene_expression of CCL11 1 1 0.05 0.37 0.23
106 INT138932 Ifng Positive_regulation of Ifng Positive_regulation of Stat1 1 1 0.18 0.28 0.23
107 INT80279 IFNG Positive_regulation of Gene_expression of CCL11 1 1 0.06 0.37 0.23
108 INT138929 Ifng Positive_regulation of Stat1 1 1 0.29 0.28 0.23
109 INT80286 IFNG Positive_regulation of Gene_expression of CCL5 1 1 0.24 0.37 0.23
110 INT138926 Regulation of Ifng Positive_regulation of Stat1 1 1 0.17 0.28 0.23
111 INT80287 IL4 Positive_regulation of Gene_expression of CCL5 1 1 0.21 0.37 0.23
112 INT35014 IFNA1 Positive_regulation of ADI1 1 1 0.03 0.17 0.23
113 INT138931 Ifng Positive_regulation of Positive_regulation of Stat1 1 1 0.31 0.28 0.23
114 INT26185 Positive_regulation of Binding of GREM1 and Cyth2 1 1 0.00 0 0.22
115 INT26186 Binding of GREM1 and Cyth2 1 1 0.00 0 0.22
116 INT35013 IFNG Positive_regulation of ADI1 1 1 0.22 0.16 0.21
117 INT26158 Binding of DBI and POMC 1 1 0.35 0.16 0.19
118 INT52306 Nr3c1 Negative_regulation of Transcription of Penk 1 1 0.26 0 0.18
119 INT32819 Binding of Penk and Gtf3a 1 1 0.04 0 0.18
120 INT98775 Abhd5 Regulation of Localization of Gcg 1 1 0.24 0 0.17
121 INT25945 Plat Regulation of App 1 1 0.15 0.25 0.17
122 INT25947 Plat Regulation of Transcription of App 1 1 0.15 0.25 0.17
123 INT61360 Regulation of TNF Positive_regulation of NFKB1 2 1 0.21 1.34 0.14
124 INT124618 IDO1 Positive_regulation of Gene_expression of GDF15 1 1 0.03 0.32 0.14
125 INT82802 Binding of ABL2 and POMC 1 1 0.00 0 0.14
126 INT84050 IL6 Positive_regulation of ITIH4 1 1 0.49 0.18 0.13
127 INT81992 IL1A Positive_regulation of Positive_regulation of Tnfsf11 1 1 0.05 0.27 0.13
128 INT136880 Pebp1 Positive_regulation of Localization of Ncoa6 1 1 0.33 0.06 0.13
129 INT81983 IL1A Positive_regulation of Positive_regulation of PTGS2 1 1 0.01 0.27 0.13
130 INT136883 Pebp1 Regulation of Localization of Casr 1 2 0.51 0 0.12
131 INT126882 Negative_regulation of TIMP1 Regulation of NA 1 1 0.28 0 0.12
132 INT136876 Ncoa6 Regulation of Localization of Casr 1 2 0.62 0 0.12
133 INT126883 TIMP1 Regulation of NA 1 1 0.17 0 0.12
134 INT128551 Binding of Cebpb and Nr3c1 1 1 0.06 0.15 0.11
135 INT71310 Il1a Positive_regulation of NOS1 1 1 0.07 0.09 0.11
136 INT71311 Il1a Positive_regulation of Positive_regulation of NOS1 1 1 0.07 0.09 0.11
137 INT116788 Bsg Negative_regulation of Gene_expression of Ptges 1 1 0.00 0.17 0.09
138 INT103323 Negative_regulation of Binding of TRPV1 and Trpv1 1 1 0.01 0 0.09
139 INT103322 Binding of TRPV1 and Trpv1 1 1 0.01 0 0.09
140 INT116792 Bsg Positive_regulation of Protein_catabolism of NOS2 1 1 0.23 0.18 0.09
141 INT116789 Bsg Positive_regulation of Gene_expression of Tgfb1 1 1 0.00 0.18 0.09
142 INT131598 Keap1 Negative_regulation of Nfe2l2 2 1 0.65 1.27 0.08
143 INT136875 Pebp1 Regulation of Localization of Ncoa6 1 1 0.37 0 0.06
144 INT136881 Ncoa6 Regulation of Pebp1 1 1 0.22 0 0.06
145 INT136879 Ncoa6 Regulation of Localization of Pebp1 1 1 0.37 0 0.06

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 9 2008 0.81 518.3 1408.65
3 INT796 Gene_expression of Penk 21 1902 0.78 275.47 1057.59
4 INT158 Localization of Prl 2 2431 0.81 378.96 952.2
5 INT6483 Gene_expression of TNF 4 3152 0.78 2515.62 929.82
6 INT3439 Localization of Abat 9 1017 0.78 112.39 727.06
7 INT5202 Positive_regulation of Gene_expression of Fos 2 1163 0.70 319.28 684
8 INT292 Localization of Penk 2 876 0.81 88.44 669.14
9 INT728 Positive_regulation of Penk 11 1068 0.70 186.9 636.87
10 INT2543 Positive_regulation of Calca 1 787 0.70 331.13 592.08
11 INT797 Regulation of Penk 3 812 0.62 111.13 542.24
12 INT5228 Positive_regulation of Fos 8 934 0.70 209.8 503.87
13 INT155 Positive_regulation of Prl 2 1233 0.70 317.93 457.82
14 INT1045 Localization of LH 2 1211 0.81 87.04 456.25
15 INT443 Localization of POMC 1 1020 0.81 284.52 443.17
16 INT50058 Negative_regulation of Cpox 1 907 0.58 426.28 428.29
17 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
18 INT1395 Negative_regulation of Penk 5 537 0.59 87.33 389.81
19 INT6056 Negative_regulation of Gene_expression of Fos 1 601 0.59 193.05 386.84
20 INT157 Positive_regulation of Localization of Prl 1 790 0.70 104.54 374.78
21 INT439 Localization of Gnrh1 2 976 0.81 100.96 363.25
22 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
23 INT5660 Binding of Oprd1 2 477 0.48 71.86 342.06
24 INT5979 Gene_expression of Oprd1 7 428 0.78 75.64 320.32
25 INT34869 Negative_regulation of PTGS2 6 778 0.59 366.76 319.85
26 INT4941 Positive_regulation of Oprd1 2 345 0.70 74.26 304.41
27 INT161 Regulation of Localization of Prl 1 615 0.62 65.37 298.66
28 INT886 Gene_expression of Pomc 1 676 0.78 129.87 295.98
29 INT11624 Gene_expression of OPRM1 5 445 0.78 72.36 294.36
30 INT5379 Gene_expression of Fos 3 656 0.78 255.5 292.54
31 INT49750 Negative_regulation of CPOX 6 735 0.58 360.06 274.19
32 INT1396 Binding of Penk 2 355 0.48 22.79 269.65
33 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
34 INT87687 Positive_regulation of Trpv1 3 409 0.70 210.24 257.59
35 INT16868 Gene_expression of Il6 3 807 0.78 499.48 256.57
36 INT2909 Positive_regulation of Abat 1 334 0.70 62.1 256.43
37 INT5597 Gene_expression of Pdyn 2 433 0.78 62.97 235.47
38 INT4759 Negative_regulation of Localization of Calca 1 294 0.59 82.62 226.45
39 INT9987 Gene_expression of Abat 5 296 0.78 95.46 226.34
40 INT1212 Binding of Oprl1 1 312 0.48 28.6 225.15
41 INT6293 Gene_expression of Oprm1 2 312 0.78 48.73 215.61
42 INT4893 Gene_expression of Tacr1 1 366 0.78 129.67 213.92
43 INT6482 Positive_regulation of Gene_expression of TNF 3 659 0.70 569.88 210
44 INT48955 Gene_expression of Nos2 12 753 0.78 403.87 208.08
45 INT798 Positive_regulation of Gene_expression of Penk 3 394 0.70 78.53 203.07
46 INT11313 Positive_regulation of Il6 3 526 0.70 331.27 201.59
47 INT50670 Gene_expression of CPOX 11 763 0.76 442.13 195.02
48 INT528 Gene_expression of Prl 2 693 0.78 217.18 192.2
49 INT6488 Gene_expression of Tnf 1 484 0.78 339.61 191.58
50 INT4803 Transcription of Penk 10 435 0.72 59.09 182.4
51 INT3440 Negative_regulation of Localization of Abat 3 221 0.57 33.94 180.36
52 INT49441 Negative_regulation of Cpox 1 494 0.59 303.22 177.46
53 INT1429 Gene_expression of PDYN 1 308 0.78 61.33 175.65
54 INT5930 Positive_regulation of Oprm1 2 221 0.70 31.19 172.93
55 INT4937 Negative_regulation of Oprd1 3 224 0.59 44.51 171.11
56 INT438 Gene_expression of Crh 1 376 0.78 159.11 169.17
57 INT739 Negative_regulation of POMC 2 358 0.59 102.28 166.77
58 INT1114 Localization of Ins1 9 748 0.80 192.95 165.48
59 INT4768 Positive_regulation of OPRM1 4 212 0.70 31.09 164.28
60 INT5513 Negative_regulation of Pomc 1 295 0.59 60.9 158.63
61 INT21185 Binding of Ptprg 3 213 0.47 13.49 157.75
62 INT6042 Binding of Oprm1 3 248 0.48 31.77 154.34
63 INT1044 Negative_regulation of Localization of LH 2 358 0.59 25.95 151.31
64 INT4829 Positive_regulation of Localization of Abat 2 199 0.55 20.91 150.48
65 INT5050 Regulation of Localization of Calca 2 149 0.62 41.25 148.57
66 INT13353 Positive_regulation of Tnf 1 332 0.70 248.75 148.1
67 INT1033 Positive_regulation of Ca2 1 507 0.68 131.76 147.64
68 INT5116 Gene_expression of IL2 1 670 0.78 291.13 146.69
69 INT2780 Regulation of Gene_expression of Penk 5 265 0.62 32.45 143.88
70 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
71 INT5061 Negative_regulation of Mme 3 306 0.59 51.97 136.9
72 INT4658 Binding of OPRM1 2 188 0.48 25.96 136.24
73 INT60126 Regulation of Trpv1 3 186 0.62 85.53 133.4
74 INT11012 Positive_regulation of Creb1 1 258 0.70 84.4 132
75 INT48953 Positive_regulation of Nos2 4 486 0.70 239.85 131.87
76 INT5380 Positive_regulation of Gene_expression of Fos 3 243 0.70 105.65 131.05
77 INT49439 Gene_expression of Cpox 1 508 0.73 326.97 130.17
78 INT5595 Positive_regulation of Pdyn 5 223 0.70 48.37 130.14
79 INT695 Binding of POMC 6 304 0.48 56.66 126.85
80 INT6822 Gene_expression of Pdyn 3 215 0.78 35.99 125.76
81 INT4824 Positive_regulation of Tacr1 1 169 0.70 66.1 123.46
82 INT2555 Positive_regulation of Localization of Penk 1 116 0.70 24.35 119.73
83 INT9235 Negative_regulation of Gene_expression of TNF 2 346 0.59 252.98 118.61
84 INT50674 Gene_expression of PTGS2 4 459 0.78 253.33 118.51
85 INT48593 Positive_regulation of NOS1 1 420 0.68 226.15 114.71
86 INT16253 Positive_regulation of Gene_expression of Bdnf 2 196 0.70 92.67 113.01
87 INT49171 Gene_expression of Nos1 2 241 0.78 140.7 104.76
88 INT69440 Gene_expression of ROS1 1 752 0.78 477.64 103.83
89 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
90 INT5587 Regulation of Fos 1 191 0.62 40.81 99.7
91 INT293 Protein_catabolism of Penk 3 161 1.00 11.71 98.45
92 INT65500 Gene_expression of App 1 605 0.78 429.94 98.31
93 INT4822 Localization of Ca2 1 417 0.80 99.57 96.45
94 INT1760 Gene_expression of PTGER2 2 524 0.57 226.94 96.4
95 INT3537 Positive_regulation of Car2 1 413 0.56 103.51 94.35
96 INT29971 Gene_expression of Oprk1 4 126 0.78 35.32 93.97
97 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
98 INT2122 Negative_regulation of Localization of Gnrh1 2 226 0.59 26.92 92.04
99 INT38731 Localization of Trpv1 4 138 0.81 52.73 90.49
100 INT6437 Binding of YY1 6 154 0.47 26.3 90.46
101 INT7180 Negative_regulation of Trib3 1 180 0.51 68.48 88.01
102 INT3441 Regulation of Localization of Abat 1 117 0.38 8.67 87.59
103 INT54571 Positive_regulation of NFKB1 4 263 0.70 138.99 87.32
104 INT5594 Regulation of Pdyn 1 137 0.62 27.04 86.63
105 INT1472 Positive_regulation of Ins1 2 349 0.69 146.2 86.36
106 INT73340 Negative_regulation of Faah 2 134 0.59 38.67 85.03
107 INT4830 Binding of Trpv1 2 158 0.48 45.11 84.2
108 INT5617 Localization of Nppa 7 266 0.81 83.51 83.89
109 INT2520 Negative_regulation of Ca2 2 271 0.57 72.13 83.71
110 INT6107 Localization of Npy 1 180 0.81 26.76 81.67
111 INT7528 Regulation of OPRM1 1 100 0.62 20.63 80.57
112 INT64636 Positive_regulation of Gene_expression of Nos2 2 242 0.70 147.52 79.53
113 INT2289 Gene_expression of PENK 2 203 0.78 55.62 79.49
114 INT12476 Negative_regulation of TRPV1 2 124 0.59 47.95 77.98
115 INT9382 Regulation of TRPV1 4 149 0.62 53.99 77.46
116 INT24958 Gene_expression of Nkx1-1 1 106 0.74 51.29 76.88
117 INT3657 Gene_expression of Ins1 4 514 0.78 321.69 75.76
118 INT25363 Negative_regulation of Trpv1 1 144 0.59 64.78 75.7
119 INT5593 Positive_regulation of Gene_expression of Pdyn 1 114 0.70 29.1 74.46
120 INT3034 Localization of Ngf 1 126 0.81 50.81 72.84
121 INT442 Localization of PDYN 1 99 0.81 11.87 72.75
122 INT6656 Gene_expression of YY1 1 135 0.75 24.73 72.16
123 INT10359 Gene_expression of Ifng 1 159 0.78 79.6 72.14
124 INT57380 Phosphorylation of Creb1 5 213 0.82 66.8 71.26
125 INT66416 Regulation of Pnoc 1 66 0.61 17.32 68.91
126 INT7534 Gene_expression of Ifng 2 193 0.78 111.02 68.6
127 INT1988 Positive_regulation of Localization of Ins1 1 254 0.69 59.25 68.37
128 INT6489 Positive_regulation of Gene_expression of Tnf 1 140 0.70 92.31 67.85
129 INT19511 Localization of Il6 10 212 0.81 118.17 67.67
130 INT11937 Localization of Il6 1 228 0.81 139.83 64.39
131 INT1951 Positive_regulation of Tlr4 1 345 0.70 176.99 62.42
132 INT5095 Localization of Ghrh 4 185 0.81 28.09 62.08
133 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
134 INT5058 Positive_regulation of IFNA1 1 356 0.70 245.75 60.52
135 INT9196 Gene_expression of PTGS1 4 215 0.77 96.99 60.5
136 INT66779 Binding of Pnoc 4 79 0.48 6.43 60.46
137 INT50672 Positive_regulation of CPOX 3 205 0.44 125.93 60.06
138 INT1536 Negative_regulation of NA 3 244 0.55 52.67 59.79
139 INT6623 Gene_expression of NA 3 231 0.78 45.78 59.36
140 INT1759 Gene_expression of TIMP1 1 267 0.77 133.87 59.29
141 INT49170 Negative_regulation of Nos1 1 116 0.59 60.66 58.87
142 INT7032 Positive_regulation of Pdyn 4 94 0.66 26.51 58.83
143 INT82055 Positive_regulation of Creb1 1 176 0.70 60.2 58.39
144 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
145 INT5819 Regulation of Localization of Penk 1 64 0.62 6.69 57.68
146 INT1510 Binding of PDYN 4 94 0.48 4.68 56.44
147 INT83602 Positive_regulation of Gene_expression of TRPV1 3 114 0.70 51.19 56.35
148 INT1463 Binding of Pomc 2 129 0.48 15.89 56.27
149 INT1200 Negative_regulation of Ins1 1 274 0.58 155.17 56.14
150 INT647 Gene_expression of SGCG 1 211 0.75 78.46 55.82
151 INT69876 Negative_regulation of Nfkb1 2 147 0.58 89.81 55.5
152 INT5598 Negative_regulation of Pdyn 2 95 0.59 14.4 55.43
153 INT2421 Positive_regulation of Positive_regulation of Penk 5 97 0.69 13.38 55.32
154 INT96533 Gene_expression of Slc1a3 2 72 0.78 26.85 55.31
155 INT78899 Gene_expression of CCL5 1 155 0.77 84.02 55.09
156 INT49436 Binding of TRPV1 5 145 0.48 38.35 55.08
157 INT6826 Transcription of Pdyn 1 130 0.71 22.19 54.88
158 INT49747 Transcription of Oprm1 1 68 0.72 9.01 53.78
159 INT47680 Regulation of Gene_expression of Bdnf 1 92 0.62 41.61 53.24
160 INT48952 Negative_regulation of Nos2 2 204 0.59 101.73 53.15
161 INT1487 Regulation of Cpe 1 68 0.62 10.24 52.91
162 INT929 Positive_regulation of Oprl1 2 64 0.70 14.67 52.84
163 INT62543 Gene_expression of Icam1 4 231 0.78 187.58 52.71
164 INT49017 Negative_regulation of Gene_expression of Nos2 8 169 0.59 80.64 52.67
165 INT5623 Positive_regulation of Nppa 5 174 0.70 69.96 52.33
166 INT5704 Binding of Slc3a1 1 78 0.43 8.52 51.78
167 INT64110 Positive_regulation of Gene_expression of Nos1 2 68 0.70 58.11 51.64
168 INT50405 Negative_regulation of CYP3A4 1 238 0.59 53.65 51.51
169 INT5338 Regulation of Npy 1 92 0.62 25.54 51.24
170 INT5136 Negative_regulation of PDYN 1 71 0.59 11.22 51.14
171 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
172 INT32718 Gene_expression of OPRD1 1 82 0.76 9.43 48.38
173 INT1977 Negative_regulation of Positive_regulation of Prl 1 98 0.59 17.06 47.88
174 INT789 Positive_regulation of YY1 1 69 0.67 14.07 47.06
175 INT873 Gene_expression of Gh1 3 130 0.76 26.15 46.75
176 INT5337 Negative_regulation of Npy 1 87 0.59 19.6 46.75
177 INT847 Regulation of Lhb 1 131 0.61 22.08 46.54
178 INT9383 Localization of TRPV1 1 98 0.81 33.23 46.24
179 INT6979 Positive_regulation of CA2 1 206 0.67 50.79 44.97
180 INT2275 Negative_regulation of Localization of Ins1 5 183 0.59 51.02 44.94
181 INT1564 Localization of OPRM1 1 41 0.80 8.03 44.67
182 INT127013 Negative_regulation of Slc1a3 1 37 0.54 14.16 43.97
183 INT1474 Regulation of Localization of Ins1 1 132 0.61 25.96 43.07
184 INT52531 Gene_expression of Nfkb1 2 153 0.75 82.84 42.9
185 INT7828 Positive_regulation of Oprd1 1 55 0.69 14.11 42.86
186 INT50957 Negative_regulation of Il6 1 134 0.59 79.08 42.67
187 INT11180 Binding of RYBP 2 52 0.46 13.86 42.53
188 INT81251 Gene_expression of Trpv2 1 78 0.78 28.27 41.76
189 INT11939 Negative_regulation of Il6 2 138 0.59 87.46 41.24
190 INT69437 Positive_regulation of ROS1 1 328 0.58 222.83 40.56
191 INT4862 Localization of PENK 2 62 0.81 11.57 40.28
192 INT5973 Regulation of IL1B 1 109 0.62 66.6 39.88
193 INT88322 Gene_expression of CCR5 2 111 0.78 77.36 39.84
194 INT55135 Positive_regulation of Gene_expression of PTGS2 2 137 0.70 80.32 38.46
195 INT2416 Negative_regulation of MAOA 1 92 0.59 42.24 36.5
196 INT5620 Positive_regulation of Localization of Nppa 2 105 0.70 30.23 36.45
197 INT84260 Positive_regulation of Mapk8 1 124 0.69 72.84 35.98
198 INT11292 Gene_expression of Mme 1 77 0.78 20.98 35.85
199 INT2296 Positive_regulation of Gene_expression of Prl 1 137 0.70 36.96 35.39
200 INT65055 Negative_regulation of Nfkb1 2 83 0.58 44.85 34.94
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