J:Biochemistry
This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.
Molecular Interactions
The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.
Int No | Page link | Interaction String | Reported in Journal | Documents | TM Confidence | Disease Relevance | Pain Relevance |
---|---|---|---|---|---|---|---|
1 | INT167484 | Binding of CHRNE and GGNBP2 | 1 | 2 | 0.02 | 0 | 0.5 |
2 | INT167488 | Binding of NEUROD1 and GGNBP2 | 1 | 1 | 0.08 | 0 | 0.27 |
3 | INT167486 | Positive_regulation of Binding of CD63 and ACOT1 | 1 | 1 | 0.01 | 0 | 0.21 |
4 | INT167485 | Binding of CD63 and ACOT1 | 1 | 1 | 0.00 | 0 | 0.21 |
5 | INT154339 | Binding of IGLL1 and MAN1A1 | 1 | 1 | 0.00 | 0 | 0.03 |
6 | INT315543 | NARFL Regulation of Gene_expression of HIF1A | 1 | 1 | 0.01 | 0.63 | 0 |
7 | INT315541 | ACO1 Negative_regulation of Gene_expression of ALAS2 | 1 | 1 | 0.17 | 0.18 | 0 |
8 | INT315534 | Binding of ACO1 and ERN1 | 1 | 1 | 0.01 | 0.18 | 0 |
9 | INT347265 | Gbp1 Negative_regulation of Maoa | 1 | 1 | 0.00 | 0 | 0 |
10 | INT315535 | Binding of ABCB7 and FECH | 1 | 1 | 0.28 | 0.7 | 0 |
11 | INT315533 | Negative_regulation of GLRX5 Negative_regulation of Gene_expression of ALAS2 | 1 | 1 | 0.38 | 1.06 | 0 |
12 | INT315532 | Binding of NFS1 and ISCU | 1 | 1 | 0.19 | 0.37 | 0 |
13 | INT315538 | Negative_regulation of GLRX5 Negative_regulation of Gene_expression of SLC40A1 | 1 | 1 | 0.25 | 1.14 | 0 |
Single Events
The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.
Int No | Page link | Event String | Reported in Journal | Documents | TM Confidence | Disease Relevance | Pain Relevance |
---|---|---|---|---|---|---|---|
1 | INT1396 | Binding of Penk | 5 | 355 | 0.48 | 22.79 | 269.65 |
2 | INT5930 | Positive_regulation of Oprm1 | 2 | 221 | 0.70 | 31.19 | 172.93 |
3 | INT5116 | Gene_expression of IL2 | 1 | 670 | 0.78 | 291.13 | 146.69 |
4 | INT695 | Binding of POMC | 3 | 304 | 0.48 | 56.66 | 126.85 |
5 | INT10304 | Binding of OPRK1 | 3 | 89 | 0.48 | 9.28 | 49.42 |
6 | INT115 | Negative_regulation of Maoa | 1 | 65 | 0.59 | 16.27 | 38.66 |
7 | INT5117 | Negative_regulation of Gene_expression of IL2 | 1 | 118 | 0.59 | 52.33 | 29.96 |
8 | INT105387 | Gene_expression of HIF1A | 1 | 116 | 0.77 | 98.62 | 14.66 |
9 | INT3623 | Negative_regulation of CTSB | 1 | 49 | 0.55 | 27.39 | 13.52 |
10 | INT65009 | Gene_expression of HTR3A | 1 | 29 | 0.75 | 8.51 | 10.59 |
11 | INT85144 | Binding of Cnr2 | 1 | 14 | 0.47 | 6.41 | 9.49 |
12 | INT58841 | Gene_expression of HTR2A | 1 | 33 | 0.75 | 9.01 | 9.07 |
13 | INT15805 | Gene_expression of TFRC | 1 | 35 | 0.75 | 17.44 | 8.52 |
14 | INT190298 | Binding of MRGPRX1 | 3 | 61 | 0.46 | 2.66 | 5.75 |
15 | INT41892 | Gene_expression of HBM | 3 | 48 | 0.64 | 28.32 | 5.64 |
16 | INT10980 | Gene_expression of GYPA | 1 | 40 | 0.78 | 15.32 | 5.51 |
17 | INT50105 | Localization of CTSB | 1 | 29 | 0.78 | 10.98 | 5.21 |
18 | INT80486 | Gene_expression of FECH | 4 | 13 | 0.54 | 10.42 | 4.8 |
19 | INT272273 | Gene_expression of NARFL | 1 | 89 | 0.54 | 121.19 | 4.47 |
20 | INT7083 | Positive_regulation of HBM | 1 | 35 | 0.66 | 20.96 | 4.3 |
21 | INT94132 | Binding of ACOT1 | 3 | 7 | 0.13 | 2.62 | 4.04 |
22 | INT168677 | Negative_regulation of ACOT1 | 1 | 14 | 0.27 | 6.29 | 3.52 |
23 | INT15801 | Positive_regulation of TFRC | 1 | 11 | 0.33 | 6.35 | 3.3 |
24 | INT32852 | Negative_regulation of FECH | 1 | 18 | 0.57 | 10.59 | 3.08 |
25 | INT112365 | Regulation of HIF1A | 1 | 27 | 0.60 | 21.24 | 3.05 |
26 | INT45179 | Gene_expression of sea | 2 | 8 | 0.58 | 3.4 | 2.99 |
27 | INT110980 | Gene_expression of CTSB | 2 | 17 | 0.45 | 8.02 | 2.69 |
28 | INT243496 | Positive_regulation of Gene_expression of FECH | 1 | 4 | 0.40 | 4.02 | 2.34 |
29 | INT110961 | Binding of GYPA | 1 | 14 | 0.36 | 6.66 | 2.03 |
30 | INT50895 | Regulation of GYPA | 1 | 10 | 0.60 | 4.05 | 1.95 |
31 | INT53567 | Positive_regulation of FECH | 3 | 14 | 0.45 | 11.03 | 1.82 |
32 | INT64378 | Gene_expression of DMRT1 | 1 | 9 | 0.54 | 1.72 | 1.71 |
33 | INT36698 | Binding of CHRM3 | 1 | 5 | 0.48 | 1.97 | 1.49 |
34 | INT15798 | Positive_regulation of Gene_expression of TFRC | 1 | 9 | 0.46 | 4.99 | 1.42 |
35 | INT162467 | Gene_expression of ERN1 | 1 | 10 | 0.56 | 5.11 | 1.26 |
36 | INT302084 | Negative_regulation of WNT2 | 1 | 2 | 0.09 | 0.83 | 1.26 |
37 | INT168675 | Binding of P4HB | 1 | 3 | 0.20 | 1.98 | 1.11 |
38 | INT115264 | Binding of FECH | 1 | 9 | 0.41 | 7.93 | 1.1 |
39 | INT76890 | Gene_expression of FGFR2 | 6 | 42 | 0.65 | 13.91 | 1.08 |
40 | INT162471 | Positive_regulation of ERN1 | 2 | 7 | 0.34 | 3.02 | 1.08 |
41 | INT15310 | Gene_expression of DLEU1 | 3 | 8 | 0.67 | 20.57 | 0.96 |
42 | INT4436 | Gene_expression of ABCB7 | 7 | 7 | 0.65 | 9.26 | 0.93 |
43 | INT41536 | Localization of ANTXR1 | 1 | 7 | 0.60 | 2.24 | 0.79 |
44 | INT140782 | Binding of GRHL1 | 2 | 1 | 0.01 | 0 | 0.79 |
45 | INT108308 | Gene_expression of ENOX1 | 3 | 10 | 0.77 | 1.65 | 0.74 |
46 | INT158136 | Binding of FGFR2 | 1 | 9 | 0.26 | 4.5 | 0.63 |
47 | INT94423 | Binding of ALAS2 | 2 | 4 | 0.32 | 2.1 | 0.61 |
48 | INT83641 | Binding of CD63 | 1 | 4 | 0.19 | 1 | 0.45 |
49 | INT167492 | Binding of GGNBP2 | 2 | 1 | 0.07 | 0 | 0.43 |
50 | INT31383 | Negative_regulation of Gbp1 | 1 | 4 | 0.41 | 1.49 | 0.41 |
51 | INT302086 | Gene_expression of WNT2 | 1 | 3 | 0.14 | 0.97 | 0.38 |
52 | INT124964 | Binding of PRB4 | 1 | 3 | 0.07 | 0.07 | 0.37 |
53 | INT154734 | Negative_regulation of Muted | 1 | 1 | 0.03 | 0 | 0.36 |
54 | INT157614 | Regulation of Muted | 1 | 2 | 0.18 | 0.2 | 0.33 |
55 | INT157613 | Regulation of Dmrtc1a | 1 | 1 | 0.01 | 0 | 0.33 |
56 | INT157615 | Regulation of C9 | 1 | 1 | 0.00 | 0 | 0.33 |
57 | INT3321 | Positive_regulation of ALAS2 | 2 | 10 | 0.51 | 3.08 | 0.32 |
58 | INT167491 | Positive_regulation of Gene_expression of GGNBP2 | 1 | 1 | 0.11 | 0 | 0.28 |
59 | INT166958 | Gene_expression of LYRM4 | 1 | 4 | 0.18 | 2.9 | 0.27 |
60 | INT167490 | Gene_expression of GGNBP2 | 1 | 1 | 0.14 | 0 | 0.27 |
61 | INT156468 | Gene_expression of SORBS3 | 1 | 1 | 0.01 | 0 | 0.26 |
62 | INT221496 | Localization of ISCA1 | 1 | 4 | 0.73 | 2.12 | 0.23 |
63 | INT243267 | Positive_regulation of SLC40A1 | 2 | 4 | 0.41 | 2.72 | 0.22 |
64 | INT241863 | Binding of SLC40A1 | 1 | 4 | 0.28 | 3.86 | 0.22 |
65 | INT134174 | Gene_expression of APLP1 | 1 | 3 | 0.77 | 1.76 | 0.22 |
66 | INT3323 | Gene_expression of ALAS2 | 8 | 10 | 0.58 | 7.51 | 0.21 |
67 | INT236980 | Gene_expression of ISCA1 | 1 | 9 | 0.53 | 2.43 | 0.19 |
68 | INT170629 | Negative_regulation of Gene_expression of ABCB7 | 1 | 2 | 0.37 | 1.32 | 0.17 |
69 | INT154340 | Binding of IGLL1 | 1 | 3 | 0.02 | 0.82 | 0.14 |
70 | INT347266 | Negative_regulation of FNTB | 1 | 1 | 0.01 | 0.29 | 0.14 |
71 | INT243268 | Gene_expression of SLC40A1 | 4 | 6 | 0.60 | 4.18 | 0.13 |
72 | INT131139 | Binding of ACO1 | 1 | 3 | 0.27 | 1.81 | 0.1 |
73 | INT95756 | Gene_expression of ACO1 | 2 | 3 | 0.27 | 2.49 | 0.1 |
74 | INT315643 | Negative_regulation of Gene_expression of FECH | 1 | 1 | 0.29 | 0.71 | 0.1 |
75 | INT156483 | Regulation of Gene_expression of GYPA | 1 | 1 | 0.00 | 0.09 | 0.1 |
76 | INT174848 | Gene_expression of ISCU | 5 | 2 | 0.59 | 2.79 | 0.08 |
77 | INT315626 | Localization of DLEU1 | 1 | 2 | 0.35 | 4.17 | 0.07 |
78 | INT168674 | Positive_regulation of Binding of ING1 | 1 | 1 | 0.10 | 0.35 | 0.07 |
79 | INT315554 | Localization of NFS1 | 1 | 1 | 0.43 | 0.28 | 0.07 |
80 | INT163551 | Protein_catabolism of Aplp1 | 1 | 1 | 0.25 | 0.15 | 0.07 |
81 | INT168673 | Binding of ING1 | 1 | 1 | 0.07 | 0.35 | 0.07 |
82 | INT315622 | Protein_catabolism of FECH | 2 | 1 | 0.77 | 0.49 | 0.07 |
83 | INT163550 | Negative_regulation of Protein_catabolism of Aplp1 | 1 | 1 | 0.11 | 0.15 | 0.07 |
84 | INT168672 | Positive_regulation of Binding of P4HB | 1 | 1 | 0.20 | 0.35 | 0.07 |
85 | INT315598 | Localization of FXN | 2 | 1 | 0.43 | 1.04 | 0.07 |
86 | INT315630 | Gene_expression of FXN | 7 | 8 | 0.64 | 20.05 | 0.05 |
87 | INT315624 | Positive_regulation of Gene_expression of ISCU | 1 | 1 | 0.38 | 0.23 | 0.03 |
88 | INT315563 | Positive_regulation of Gene_expression of FXN | 4 | 4 | 0.41 | 5.05 | 0 |
89 | INT3322 | Positive_regulation of Gene_expression of ALAS2 | 3 | 4 | 0.43 | 3.25 | 0 |
90 | INT315635 | Positive_regulation of FXN | 1 | 2 | 0.41 | 5.76 | 0 |
91 | INT252722 | Binding of IREB2 | 1 | 2 | 0.16 | 1.31 | 0 |
92 | INT174850 | Binding of ISCU | 4 | 2 | 0.33 | 0.51 | 0 |
93 | INT296387 | Localization of SLC40A1 | 1 | 2 | 0.44 | 0.94 | 0 |
94 | INT315628 | Negative_regulation of Gene_expression of FXN | 1 | 2 | 0.36 | 2.37 | 0 |
95 | INT315561 | Regulation of ISCU | 1 | 2 | 0.35 | 1.1 | 0 |
96 | INT315583 | Positive_regulation of Binding of NFS1 | 1 | 1 | 0.25 | 0 | 0 |
97 | INT315551 | Negative_regulation of Gene_expression of ALAS2 | 1 | 1 | 0.37 | 1.11 | 0 |
98 | INT315585 | Localization of SLC25A37 | 1 | 1 | 0.13 | 0.47 | 0 |
99 | INT315581 | Positive_regulation of Phosphorylation of ISCU | 1 | 1 | 0.44 | 0.33 | 0 |
100 | INT315617 | Positive_regulation of Gene_expression of SLC25A37 | 1 | 1 | 0.10 | 0.39 | 0 |
101 | INT315565 | Negative_regulation of Gene_expression of SLC40A1 | 2 | 1 | 0.25 | 1.73 | 0 |
102 | INT315631 | Protein_catabolism of IREB2 | 1 | 1 | 0.44 | 0.4 | 0 |
103 | INT315614 | Negative_regulation of Transcription of FXN | 1 | 1 | 0.25 | 0.82 | 0 |
104 | INT315602 | Binding of ISCA1 | 2 | 1 | 0.30 | 0 | 0 |
105 | INT315562 | Gene_expression of GLRX5 | 9 | 1 | 0.69 | 4.92 | 0 |
106 | INT315587 | Positive_regulation of Gene_expression of CIAO1 | 2 | 1 | 0.22 | 1.6 | 0 |
107 | INT315591 | Negative_regulation of Positive_regulation of SLC40A1 | 1 | 1 | 0.25 | 0.46 | 0 |
108 | INT315620 | Regulation of Gene_expression of GLRX5 | 1 | 1 | 0.40 | 0.5 | 0 |
109 | INT315550 | Transcription of GLRX5 | 1 | 1 | 0.53 | 0.66 | 0 |
110 | INT315575 | Transcription of SLC40A1 | 1 | 1 | 0.40 | 0.85 | 0 |
111 | INT315637 | Transcription of FXN | 2 | 1 | 0.40 | 1.44 | 0 |
112 | INT315634 | Negative_regulation of Binding of ISCU | 1 | 1 | 0.33 | 0.28 | 0 |
113 | INT315597 | Negative_regulation of ISCU | 1 | 1 | 0.51 | 0.22 | 0 |
114 | INT315600 | Regulation of CIAO1 | 1 | 1 | 0.20 | 0.39 | 0 |
115 | INT315571 | Binding of NFS1 | 1 | 1 | 0.19 | 0 | 0 |
116 | INT315613 | Positive_regulation of WNT2 | 1 | 1 | 0.09 | 0.41 | 0 |
117 | INT315627 | Binding of GLRX5 | 1 | 1 | 0.33 | 0 | 0 |
118 | INT315606 | Regulation of Gene_expression of WNT2 | 1 | 1 | 0.08 | 0.84 | 0 |
119 | INT315644 | Negative_regulation of Transcription of DLEU1 | 2 | 1 | 0.21 | 0.64 | 0 |
120 | INT315555 | Binding of FXN | 3 | 1 | 0.28 | 1.29 | 0 |
121 | INT315605 | Binding of ABCB7 | 3 | 1 | 0.33 | 1.84 | 0 |
122 | INT315592 | Positive_regulation of Gene_expression of SLC40A1 | 3 | 1 | 0.41 | 3.52 | 0 |
123 | INT315640 | Gene_expression of NUBP1 | 5 | 1 | 0.41 | 0.32 | 0 |
124 | INT315567 | Positive_regulation of Negative_regulation of CIAO1 | 1 | 1 | 0.22 | 1.29 | 0 |
125 | INT315556 | Positive_regulation of Binding of ALAS2 | 1 | 1 | 0.43 | 1.05 | 0 |
126 | INT315623 | Positive_regulation of Localization of ACO1 | 1 | 1 | 0.20 | 0.79 | 0 |
127 | INT315608 | Localization of NFU1 | 1 | 1 | 0.14 | 0 | 0 |
128 | INT315596 | Localization of ISCA2 | 1 | 1 | 0.11 | 0 | 0 |
129 | INT315601 | Positive_regulation of NFU1 | 1 | 1 | 0.22 | 0.13 | 0 |
130 | INT315642 | Negative_regulation of Gene_expression of NFU1 | 1 | 1 | 0.16 | 0.37 | 0 |
131 | INT315636 | Negative_regulation of ABCB7 | 1 | 1 | 0.38 | 0.17 | 0 |
132 | INT315588 | Regulation of ACO1 | 2 | 1 | 0.18 | 0.57 | 0 |
133 | INT315570 | Negative_regulation of Positive_regulation of TFRC | 1 | 1 | 0.19 | 0.08 | 0 |
134 | INT315573 | Negative_regulation of Gene_expression of NFS1 | 2 | 1 | 0.24 | 0.74 | 0 |
135 | INT315568 | Regulation of Gene_expression of CIAO1 | 1 | 1 | 0.20 | 0.15 | 0 |
136 | INT315638 | Gene_expression of GLRX3 | 1 | 1 | 0.25 | 0 | 0 |
137 | INT315564 | Binding of NFU1 | 2 | 1 | 0.16 | 0 | 0 |
138 | INT315619 | Regulation of Gene_expression of NFS1 | 2 | 1 | 0.26 | 0.74 | 0 |
139 | INT315607 | Positive_regulation of Gene_expression of GLRX5 | 5 | 1 | 0.61 | 2.28 | 0 |
140 | INT315593 | Regulation of Transcription of SLC40A1 | 2 | 1 | 0.26 | 1.7 | 0 |
141 | INT315549 | Negative_regulation of Binding of WNT2 | 1 | 1 | 0.08 | 0.65 | 0 |
142 | INT315580 | Negative_regulation of Localization of SLC40A1 | 1 | 1 | 0.25 | 0.64 | 0 |
143 | INT315641 | Gene_expression of ISCA2 | 1 | 1 | 0.22 | 0 | 0 |
144 | INT315590 | Negative_regulation of Transcription of CIAO1 | 1 | 1 | 0.19 | 0.33 | 0 |
145 | INT315612 | Gene_expression of NFS1 | 5 | 1 | 0.39 | 1.68 | 0 |
146 | INT315610 | Transcription of DLEU1 | 2 | 1 | 0.25 | 0.64 | 0 |
147 | INT315576 | Positive_regulation of Binding of CIAO1 | 1 | 1 | 0.22 | 0.67 | 0 |
148 | INT315615 | Positive_regulation of ISCU | 1 | 1 | 0.44 | 0.11 | 0 |
149 | INT315589 | Binding of CIAO1 | 1 | 1 | 0.16 | 0.67 | 0 |
150 | INT315599 | Binding of ISCA2 | 2 | 1 | 0.12 | 0 | 0 |
151 | INT315639 | Localization of ISCU | 1 | 1 | 0.66 | 0 | 0 |
152 | INT315560 | Gene_expression of SLC19A2 | 3 | 1 | 0.55 | 1.32 | 0 |
153 | INT315629 | Phosphorylation of ISCU | 1 | 1 | 0.71 | 0.33 | 0 |
154 | INT315586 | Gene_expression of SLC25A38 | 1 | 1 | 0.52 | 0.51 | 0 |
155 | INT315604 | Negative_regulation of Positive_regulation of WNT2 | 1 | 1 | 0.08 | 0.41 | 0 |
156 | INT315552 | Negative_regulation of GLRX5 | 2 | 1 | 0.38 | 2.17 | 0 |
157 | INT315559 | Negative_regulation of CIAO1 | 3 | 1 | 0.19 | 2.53 | 0 |
158 | INT315618 | Gene_expression of SLC25A37 | 1 | 1 | 0.14 | 0.38 | 0 |
159 | INT315574 | Localization of ACO1 | 1 | 1 | 0.30 | 0.79 | 0 |
160 | INT315616 | Positive_regulation of Gene_expression of ACO1 | 1 | 1 | 0.20 | 0.79 | 0 |
161 | INT315569 | Transcription of CIAO1 | 1 | 1 | 0.30 | 0.33 | 0 |
162 | INT315572 | Positive_regulation of ACO1 | 2 | 1 | 0.20 | 0.94 | 0 |
163 | INT315566 | Negative_regulation of Binding of ABCB7 | 1 | 1 | 0.37 | 0.62 | 0 |
164 | INT315548 | Gene_expression of NFU1 | 3 | 1 | 0.29 | 0.67 | 0 |
165 | INT315579 | Binding of WNT2 | 1 | 1 | 0.07 | 0.65 | 0 |
166 | INT315621 | Gene_expression of CIAO1 | 11 | 1 | 0.34 | 4.11 | 0 |
167 | INT315553 | Positive_regulation of GLRX5 | 1 | 1 | 0.44 | 0.68 | 0 |
168 | INT315632 | Positive_regulation of Protein_catabolism of IREB2 | 1 | 1 | 0.22 | 0.4 | 0 |
169 | INT315603 | Positive_regulation of Gene_expression of SLC19A2 | 1 | 1 | 0.41 | 0.48 | 0 |
170 | INT315611 | Binding of LYRM4 | 1 | 1 | 0.14 | 0 | 0 |
171 | INT315577 | Regulation of Gene_expression of NFU1 | 1 | 1 | 0.17 | 0.37 | 0 |
172 | INT315558 | Negative_regulation of SLC40A1 | 1 | 1 | 0.25 | 0.63 | 0 |