J:Biochemistry

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT167484 Binding of CHRNE and GGNBP2 1 2 0.02 0 0.5
2 INT167488 Binding of NEUROD1 and GGNBP2 1 1 0.08 0 0.27
3 INT167486 Positive_regulation of Binding of CD63 and ACOT1 1 1 0.01 0 0.21
4 INT167485 Binding of CD63 and ACOT1 1 1 0.00 0 0.21
5 INT154339 Binding of IGLL1 and MAN1A1 1 1 0.00 0 0.03
6 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 1 0.01 0.63 0
7 INT315541 ACO1 Negative_regulation of Gene_expression of ALAS2 1 1 0.17 0.18 0
8 INT315534 Binding of ACO1 and ERN1 1 1 0.01 0.18 0
9 INT347265 Gbp1 Negative_regulation of Maoa 1 1 0.00 0 0
10 INT315535 Binding of ABCB7 and FECH 1 1 0.28 0.7 0
11 INT315533 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of ALAS2 1 1 0.38 1.06 0
12 INT315532 Binding of NFS1 and ISCU 1 1 0.19 0.37 0
13 INT315538 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of SLC40A1 1 1 0.25 1.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT1396 Binding of Penk 5 355 0.48 22.79 269.65
2 INT5930 Positive_regulation of Oprm1 2 221 0.70 31.19 172.93
3 INT5116 Gene_expression of IL2 1 670 0.78 291.13 146.69
4 INT695 Binding of POMC 3 304 0.48 56.66 126.85
5 INT10304 Binding of OPRK1 3 89 0.48 9.28 49.42
6 INT115 Negative_regulation of Maoa 1 65 0.59 16.27 38.66
7 INT5117 Negative_regulation of Gene_expression of IL2 1 118 0.59 52.33 29.96
8 INT105387 Gene_expression of HIF1A 1 116 0.77 98.62 14.66
9 INT3623 Negative_regulation of CTSB 1 49 0.55 27.39 13.52
10 INT65009 Gene_expression of HTR3A 1 29 0.75 8.51 10.59
11 INT85144 Binding of Cnr2 1 14 0.47 6.41 9.49
12 INT58841 Gene_expression of HTR2A 1 33 0.75 9.01 9.07
13 INT15805 Gene_expression of TFRC 1 35 0.75 17.44 8.52
14 INT190298 Binding of MRGPRX1 3 61 0.46 2.66 5.75
15 INT41892 Gene_expression of HBM 3 48 0.64 28.32 5.64
16 INT10980 Gene_expression of GYPA 1 40 0.78 15.32 5.51
17 INT50105 Localization of CTSB 1 29 0.78 10.98 5.21
18 INT80486 Gene_expression of FECH 4 13 0.54 10.42 4.8
19 INT272273 Gene_expression of NARFL 1 89 0.54 121.19 4.47
20 INT7083 Positive_regulation of HBM 1 35 0.66 20.96 4.3
21 INT94132 Binding of ACOT1 3 7 0.13 2.62 4.04
22 INT168677 Negative_regulation of ACOT1 1 14 0.27 6.29 3.52
23 INT15801 Positive_regulation of TFRC 1 11 0.33 6.35 3.3
24 INT32852 Negative_regulation of FECH 1 18 0.57 10.59 3.08
25 INT112365 Regulation of HIF1A 1 27 0.60 21.24 3.05
26 INT45179 Gene_expression of sea 2 8 0.58 3.4 2.99
27 INT110980 Gene_expression of CTSB 2 17 0.45 8.02 2.69
28 INT243496 Positive_regulation of Gene_expression of FECH 1 4 0.40 4.02 2.34
29 INT110961 Binding of GYPA 1 14 0.36 6.66 2.03
30 INT50895 Regulation of GYPA 1 10 0.60 4.05 1.95
31 INT53567 Positive_regulation of FECH 3 14 0.45 11.03 1.82
32 INT64378 Gene_expression of DMRT1 1 9 0.54 1.72 1.71
33 INT36698 Binding of CHRM3 1 5 0.48 1.97 1.49
34 INT15798 Positive_regulation of Gene_expression of TFRC 1 9 0.46 4.99 1.42
35 INT162467 Gene_expression of ERN1 1 10 0.56 5.11 1.26
36 INT302084 Negative_regulation of WNT2 1 2 0.09 0.83 1.26
37 INT168675 Binding of P4HB 1 3 0.20 1.98 1.11
38 INT115264 Binding of FECH 1 9 0.41 7.93 1.1
39 INT76890 Gene_expression of FGFR2 6 42 0.65 13.91 1.08
40 INT162471 Positive_regulation of ERN1 2 7 0.34 3.02 1.08
41 INT15310 Gene_expression of DLEU1 3 8 0.67 20.57 0.96
42 INT4436 Gene_expression of ABCB7 7 7 0.65 9.26 0.93
43 INT41536 Localization of ANTXR1 1 7 0.60 2.24 0.79
44 INT140782 Binding of GRHL1 2 1 0.01 0 0.79
45 INT108308 Gene_expression of ENOX1 3 10 0.77 1.65 0.74
46 INT158136 Binding of FGFR2 1 9 0.26 4.5 0.63
47 INT94423 Binding of ALAS2 2 4 0.32 2.1 0.61
48 INT83641 Binding of CD63 1 4 0.19 1 0.45
49 INT167492 Binding of GGNBP2 2 1 0.07 0 0.43
50 INT31383 Negative_regulation of Gbp1 1 4 0.41 1.49 0.41
51 INT302086 Gene_expression of WNT2 1 3 0.14 0.97 0.38
52 INT124964 Binding of PRB4 1 3 0.07 0.07 0.37
53 INT154734 Negative_regulation of Muted 1 1 0.03 0 0.36
54 INT157614 Regulation of Muted 1 2 0.18 0.2 0.33
55 INT157613 Regulation of Dmrtc1a 1 1 0.01 0 0.33
56 INT157615 Regulation of C9 1 1 0.00 0 0.33
57 INT3321 Positive_regulation of ALAS2 2 10 0.51 3.08 0.32
58 INT167491 Positive_regulation of Gene_expression of GGNBP2 1 1 0.11 0 0.28
59 INT166958 Gene_expression of LYRM4 1 4 0.18 2.9 0.27
60 INT167490 Gene_expression of GGNBP2 1 1 0.14 0 0.27
61 INT156468 Gene_expression of SORBS3 1 1 0.01 0 0.26
62 INT221496 Localization of ISCA1 1 4 0.73 2.12 0.23
63 INT243267 Positive_regulation of SLC40A1 2 4 0.41 2.72 0.22
64 INT241863 Binding of SLC40A1 1 4 0.28 3.86 0.22
65 INT134174 Gene_expression of APLP1 1 3 0.77 1.76 0.22
66 INT3323 Gene_expression of ALAS2 8 10 0.58 7.51 0.21
67 INT236980 Gene_expression of ISCA1 1 9 0.53 2.43 0.19
68 INT170629 Negative_regulation of Gene_expression of ABCB7 1 2 0.37 1.32 0.17
69 INT154340 Binding of IGLL1 1 3 0.02 0.82 0.14
70 INT347266 Negative_regulation of FNTB 1 1 0.01 0.29 0.14
71 INT243268 Gene_expression of SLC40A1 4 6 0.60 4.18 0.13
72 INT131139 Binding of ACO1 1 3 0.27 1.81 0.1
73 INT95756 Gene_expression of ACO1 2 3 0.27 2.49 0.1
74 INT315643 Negative_regulation of Gene_expression of FECH 1 1 0.29 0.71 0.1
75 INT156483 Regulation of Gene_expression of GYPA 1 1 0.00 0.09 0.1
76 INT174848 Gene_expression of ISCU 5 2 0.59 2.79 0.08
77 INT315626 Localization of DLEU1 1 2 0.35 4.17 0.07
78 INT168674 Positive_regulation of Binding of ING1 1 1 0.10 0.35 0.07
79 INT315554 Localization of NFS1 1 1 0.43 0.28 0.07
80 INT163551 Protein_catabolism of Aplp1 1 1 0.25 0.15 0.07
81 INT168673 Binding of ING1 1 1 0.07 0.35 0.07
82 INT315622 Protein_catabolism of FECH 2 1 0.77 0.49 0.07
83 INT163550 Negative_regulation of Protein_catabolism of Aplp1 1 1 0.11 0.15 0.07
84 INT168672 Positive_regulation of Binding of P4HB 1 1 0.20 0.35 0.07
85 INT315598 Localization of FXN 2 1 0.43 1.04 0.07
86 INT315630 Gene_expression of FXN 7 8 0.64 20.05 0.05
87 INT315624 Positive_regulation of Gene_expression of ISCU 1 1 0.38 0.23 0.03
88 INT315563 Positive_regulation of Gene_expression of FXN 4 4 0.41 5.05 0
89 INT3322 Positive_regulation of Gene_expression of ALAS2 3 4 0.43 3.25 0
90 INT315635 Positive_regulation of FXN 1 2 0.41 5.76 0
91 INT252722 Binding of IREB2 1 2 0.16 1.31 0
92 INT174850 Binding of ISCU 4 2 0.33 0.51 0
93 INT296387 Localization of SLC40A1 1 2 0.44 0.94 0
94 INT315628 Negative_regulation of Gene_expression of FXN 1 2 0.36 2.37 0
95 INT315561 Regulation of ISCU 1 2 0.35 1.1 0
96 INT315583 Positive_regulation of Binding of NFS1 1 1 0.25 0 0
97 INT315551 Negative_regulation of Gene_expression of ALAS2 1 1 0.37 1.11 0
98 INT315585 Localization of SLC25A37 1 1 0.13 0.47 0
99 INT315581 Positive_regulation of Phosphorylation of ISCU 1 1 0.44 0.33 0
100 INT315617 Positive_regulation of Gene_expression of SLC25A37 1 1 0.10 0.39 0
101 INT315565 Negative_regulation of Gene_expression of SLC40A1 2 1 0.25 1.73 0
102 INT315631 Protein_catabolism of IREB2 1 1 0.44 0.4 0
103 INT315614 Negative_regulation of Transcription of FXN 1 1 0.25 0.82 0
104 INT315602 Binding of ISCA1 2 1 0.30 0 0
105 INT315562 Gene_expression of GLRX5 9 1 0.69 4.92 0
106 INT315587 Positive_regulation of Gene_expression of CIAO1 2 1 0.22 1.6 0
107 INT315591 Negative_regulation of Positive_regulation of SLC40A1 1 1 0.25 0.46 0
108 INT315620 Regulation of Gene_expression of GLRX5 1 1 0.40 0.5 0
109 INT315550 Transcription of GLRX5 1 1 0.53 0.66 0
110 INT315575 Transcription of SLC40A1 1 1 0.40 0.85 0
111 INT315637 Transcription of FXN 2 1 0.40 1.44 0
112 INT315634 Negative_regulation of Binding of ISCU 1 1 0.33 0.28 0
113 INT315597 Negative_regulation of ISCU 1 1 0.51 0.22 0
114 INT315600 Regulation of CIAO1 1 1 0.20 0.39 0
115 INT315571 Binding of NFS1 1 1 0.19 0 0
116 INT315613 Positive_regulation of WNT2 1 1 0.09 0.41 0
117 INT315627 Binding of GLRX5 1 1 0.33 0 0
118 INT315606 Regulation of Gene_expression of WNT2 1 1 0.08 0.84 0
119 INT315644 Negative_regulation of Transcription of DLEU1 2 1 0.21 0.64 0
120 INT315555 Binding of FXN 3 1 0.28 1.29 0
121 INT315605 Binding of ABCB7 3 1 0.33 1.84 0
122 INT315592 Positive_regulation of Gene_expression of SLC40A1 3 1 0.41 3.52 0
123 INT315640 Gene_expression of NUBP1 5 1 0.41 0.32 0
124 INT315567 Positive_regulation of Negative_regulation of CIAO1 1 1 0.22 1.29 0
125 INT315556 Positive_regulation of Binding of ALAS2 1 1 0.43 1.05 0
126 INT315623 Positive_regulation of Localization of ACO1 1 1 0.20 0.79 0
127 INT315608 Localization of NFU1 1 1 0.14 0 0
128 INT315596 Localization of ISCA2 1 1 0.11 0 0
129 INT315601 Positive_regulation of NFU1 1 1 0.22 0.13 0
130 INT315642 Negative_regulation of Gene_expression of NFU1 1 1 0.16 0.37 0
131 INT315636 Negative_regulation of ABCB7 1 1 0.38 0.17 0
132 INT315588 Regulation of ACO1 2 1 0.18 0.57 0
133 INT315570 Negative_regulation of Positive_regulation of TFRC 1 1 0.19 0.08 0
134 INT315573 Negative_regulation of Gene_expression of NFS1 2 1 0.24 0.74 0
135 INT315568 Regulation of Gene_expression of CIAO1 1 1 0.20 0.15 0
136 INT315638 Gene_expression of GLRX3 1 1 0.25 0 0
137 INT315564 Binding of NFU1 2 1 0.16 0 0
138 INT315619 Regulation of Gene_expression of NFS1 2 1 0.26 0.74 0
139 INT315607 Positive_regulation of Gene_expression of GLRX5 5 1 0.61 2.28 0
140 INT315593 Regulation of Transcription of SLC40A1 2 1 0.26 1.7 0
141 INT315549 Negative_regulation of Binding of WNT2 1 1 0.08 0.65 0
142 INT315580 Negative_regulation of Localization of SLC40A1 1 1 0.25 0.64 0
143 INT315641 Gene_expression of ISCA2 1 1 0.22 0 0
144 INT315590 Negative_regulation of Transcription of CIAO1 1 1 0.19 0.33 0
145 INT315612 Gene_expression of NFS1 5 1 0.39 1.68 0
146 INT315610 Transcription of DLEU1 2 1 0.25 0.64 0
147 INT315576 Positive_regulation of Binding of CIAO1 1 1 0.22 0.67 0
148 INT315615 Positive_regulation of ISCU 1 1 0.44 0.11 0
149 INT315589 Binding of CIAO1 1 1 0.16 0.67 0
150 INT315599 Binding of ISCA2 2 1 0.12 0 0
151 INT315639 Localization of ISCU 1 1 0.66 0 0
152 INT315560 Gene_expression of SLC19A2 3 1 0.55 1.32 0
153 INT315629 Phosphorylation of ISCU 1 1 0.71 0.33 0
154 INT315586 Gene_expression of SLC25A38 1 1 0.52 0.51 0
155 INT315604 Negative_regulation of Positive_regulation of WNT2 1 1 0.08 0.41 0
156 INT315552 Negative_regulation of GLRX5 2 1 0.38 2.17 0
157 INT315559 Negative_regulation of CIAO1 3 1 0.19 2.53 0
158 INT315618 Gene_expression of SLC25A37 1 1 0.14 0.38 0
159 INT315574 Localization of ACO1 1 1 0.30 0.79 0
160 INT315616 Positive_regulation of Gene_expression of ACO1 1 1 0.20 0.79 0
161 INT315569 Transcription of CIAO1 1 1 0.30 0.33 0
162 INT315572 Positive_regulation of ACO1 2 1 0.20 0.94 0
163 INT315566 Negative_regulation of Binding of ABCB7 1 1 0.37 0.62 0
164 INT315548 Gene_expression of NFU1 3 1 0.29 0.67 0
165 INT315579 Binding of WNT2 1 1 0.07 0.65 0
166 INT315621 Gene_expression of CIAO1 11 1 0.34 4.11 0
167 INT315553 Positive_regulation of GLRX5 1 1 0.44 0.68 0
168 INT315632 Positive_regulation of Protein_catabolism of IREB2 1 1 0.22 0.4 0
169 INT315603 Positive_regulation of Gene_expression of SLC19A2 1 1 0.41 0.48 0
170 INT315611 Binding of LYRM4 1 1 0.14 0 0
171 INT315577 Regulation of Gene_expression of NFU1 1 1 0.17 0.37 0
172 INT315558 Negative_regulation of SLC40A1 1 1 0.25 0.63 0
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