J:Biochemistry

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT167484	Binding of CHRNE and GGNBP2	1	2	0.02	0	0.5
2	INT167488	Binding of NEUROD1 and GGNBP2	1	1	0.08	0	0.27
3	INT167486	Positive_regulation of Binding of CD63 and ACOT1	1	1	0.01	0	0.21
4	INT167485	Binding of CD63 and ACOT1	1	1	0.00	0	0.21
5	INT154339	Binding of IGLL1 and MAN1A1	1	1	0.00	0	0.03
6	INT315543	NARFL Regulation of Gene_expression of HIF1A	1	1	0.01	0.63	0
7	INT315541	ACO1 Negative_regulation of Gene_expression of ALAS2	1	1	0.17	0.18	0
8	INT315534	Binding of ACO1 and ERN1	1	1	0.01	0.18	0
9	INT347265	Gbp1 Negative_regulation of Maoa	1	1	0.00	0	0
10	INT315535	Binding of ABCB7 and FECH	1	1	0.28	0.7	0
11	INT315533	Negative_regulation of GLRX5 Negative_regulation of Gene_expression of ALAS2	1	1	0.38	1.06	0
12	INT315532	Binding of NFS1 and ISCU	1	1	0.19	0.37	0
13	INT315538	Negative_regulation of GLRX5 Negative_regulation of Gene_expression of SLC40A1	1	1	0.25	1.14	0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT1396	Binding of Penk	5	355	0.48	22.79	269.65
2	INT5930	Positive_regulation of Oprm1	2	221	0.70	31.19	172.93
3	INT5116	Gene_expression of IL2	1	670	0.78	291.13	146.69
4	INT695	Binding of POMC	3	304	0.48	56.66	126.85
5	INT10304	Binding of OPRK1	3	89	0.48	9.28	49.42
6	INT115	Negative_regulation of Maoa	1	65	0.59	16.27	38.66
7	INT5117	Negative_regulation of Gene_expression of IL2	1	118	0.59	52.33	29.96
8	INT105387	Gene_expression of HIF1A	1	116	0.77	98.62	14.66
9	INT3623	Negative_regulation of CTSB	1	49	0.55	27.39	13.52
10	INT65009	Gene_expression of HTR3A	1	29	0.75	8.51	10.59
11	INT85144	Binding of Cnr2	1	14	0.47	6.41	9.49
12	INT58841	Gene_expression of HTR2A	1	33	0.75	9.01	9.07
13	INT15805	Gene_expression of TFRC	1	35	0.75	17.44	8.52
14	INT190298	Binding of MRGPRX1	3	61	0.46	2.66	5.75
15	INT41892	Gene_expression of HBM	3	48	0.64	28.32	5.64
16	INT10980	Gene_expression of GYPA	1	40	0.78	15.32	5.51
17	INT50105	Localization of CTSB	1	29	0.78	10.98	5.21
18	INT80486	Gene_expression of FECH	4	13	0.54	10.42	4.8
19	INT272273	Gene_expression of NARFL	1	89	0.54	121.19	4.47
20	INT7083	Positive_regulation of HBM	1	35	0.66	20.96	4.3
21	INT94132	Binding of ACOT1	3	7	0.13	2.62	4.04
22	INT168677	Negative_regulation of ACOT1	1	14	0.27	6.29	3.52
23	INT15801	Positive_regulation of TFRC	1	11	0.33	6.35	3.3
24	INT32852	Negative_regulation of FECH	1	18	0.57	10.59	3.08
25	INT112365	Regulation of HIF1A	1	27	0.60	21.24	3.05
26	INT45179	Gene_expression of sea	2	8	0.58	3.4	2.99
27	INT110980	Gene_expression of CTSB	2	17	0.45	8.02	2.69
28	INT243496	Positive_regulation of Gene_expression of FECH	1	4	0.40	4.02	2.34
29	INT110961	Binding of GYPA	1	14	0.36	6.66	2.03
30	INT50895	Regulation of GYPA	1	10	0.60	4.05	1.95
31	INT53567	Positive_regulation of FECH	3	14	0.45	11.03	1.82
32	INT64378	Gene_expression of DMRT1	1	9	0.54	1.72	1.71
33	INT36698	Binding of CHRM3	1	5	0.48	1.97	1.49
34	INT15798	Positive_regulation of Gene_expression of TFRC	1	9	0.46	4.99	1.42
35	INT162467	Gene_expression of ERN1	1	10	0.56	5.11	1.26
36	INT302084	Negative_regulation of WNT2	1	2	0.09	0.83	1.26
37	INT168675	Binding of P4HB	1	3	0.20	1.98	1.11
38	INT115264	Binding of FECH	1	9	0.41	7.93	1.1
39	INT76890	Gene_expression of FGFR2	6	42	0.65	13.91	1.08
40	INT162471	Positive_regulation of ERN1	2	7	0.34	3.02	1.08
41	INT15310	Gene_expression of DLEU1	3	8	0.67	20.57	0.96
42	INT4436	Gene_expression of ABCB7	7	7	0.65	9.26	0.93
43	INT41536	Localization of ANTXR1	1	7	0.60	2.24	0.79
44	INT140782	Binding of GRHL1	2	1	0.01	0	0.79
45	INT108308	Gene_expression of ENOX1	3	10	0.77	1.65	0.74
46	INT158136	Binding of FGFR2	1	9	0.26	4.5	0.63
47	INT94423	Binding of ALAS2	2	4	0.32	2.1	0.61
48	INT83641	Binding of CD63	1	4	0.19	1	0.45
49	INT167492	Binding of GGNBP2	2	1	0.07	0	0.43
50	INT31383	Negative_regulation of Gbp1	1	4	0.41	1.49	0.41
51	INT302086	Gene_expression of WNT2	1	3	0.14	0.97	0.38
52	INT124964	Binding of PRB4	1	3	0.07	0.07	0.37
53	INT154734	Negative_regulation of Muted	1	1	0.03	0	0.36
54	INT157614	Regulation of Muted	1	2	0.18	0.2	0.33
55	INT157613	Regulation of Dmrtc1a	1	1	0.01	0	0.33
56	INT157615	Regulation of C9	1	1	0.00	0	0.33
57	INT3321	Positive_regulation of ALAS2	2	10	0.51	3.08	0.32
58	INT167491	Positive_regulation of Gene_expression of GGNBP2	1	1	0.11	0	0.28
59	INT166958	Gene_expression of LYRM4	1	4	0.18	2.9	0.27
60	INT167490	Gene_expression of GGNBP2	1	1	0.14	0	0.27
61	INT156468	Gene_expression of SORBS3	1	1	0.01	0	0.26
62	INT221496	Localization of ISCA1	1	4	0.73	2.12	0.23
63	INT243267	Positive_regulation of SLC40A1	2	4	0.41	2.72	0.22
64	INT241863	Binding of SLC40A1	1	4	0.28	3.86	0.22
65	INT134174	Gene_expression of APLP1	1	3	0.77	1.76	0.22
66	INT3323	Gene_expression of ALAS2	8	10	0.58	7.51	0.21
67	INT236980	Gene_expression of ISCA1	1	9	0.53	2.43	0.19
68	INT170629	Negative_regulation of Gene_expression of ABCB7	1	2	0.37	1.32	0.17
69	INT154340	Binding of IGLL1	1	3	0.02	0.82	0.14
70	INT347266	Negative_regulation of FNTB	1	1	0.01	0.29	0.14
71	INT243268	Gene_expression of SLC40A1	4	6	0.60	4.18	0.13
72	INT131139	Binding of ACO1	1	3	0.27	1.81	0.1
73	INT95756	Gene_expression of ACO1	2	3	0.27	2.49	0.1
74	INT315643	Negative_regulation of Gene_expression of FECH	1	1	0.29	0.71	0.1
75	INT156483	Regulation of Gene_expression of GYPA	1	1	0.00	0.09	0.1
76	INT174848	Gene_expression of ISCU	5	2	0.59	2.79	0.08
77	INT315626	Localization of DLEU1	1	2	0.35	4.17	0.07
78	INT168674	Positive_regulation of Binding of ING1	1	1	0.10	0.35	0.07
79	INT315554	Localization of NFS1	1	1	0.43	0.28	0.07
80	INT163551	Protein_catabolism of Aplp1	1	1	0.25	0.15	0.07
81	INT168673	Binding of ING1	1	1	0.07	0.35	0.07
82	INT315622	Protein_catabolism of FECH	2	1	0.77	0.49	0.07
83	INT163550	Negative_regulation of Protein_catabolism of Aplp1	1	1	0.11	0.15	0.07
84	INT168672	Positive_regulation of Binding of P4HB	1	1	0.20	0.35	0.07
85	INT315598	Localization of FXN	2	1	0.43	1.04	0.07
86	INT315630	Gene_expression of FXN	7	8	0.64	20.05	0.05
87	INT315624	Positive_regulation of Gene_expression of ISCU	1	1	0.38	0.23	0.03
88	INT315563	Positive_regulation of Gene_expression of FXN	4	4	0.41	5.05	0
89	INT3322	Positive_regulation of Gene_expression of ALAS2	3	4	0.43	3.25	0
90	INT315635	Positive_regulation of FXN	1	2	0.41	5.76	0
91	INT252722	Binding of IREB2	1	2	0.16	1.31	0
92	INT174850	Binding of ISCU	4	2	0.33	0.51	0
93	INT296387	Localization of SLC40A1	1	2	0.44	0.94	0
94	INT315628	Negative_regulation of Gene_expression of FXN	1	2	0.36	2.37	0
95	INT315561	Regulation of ISCU	1	2	0.35	1.1	0
96	INT315583	Positive_regulation of Binding of NFS1	1	1	0.25	0	0
97	INT315551	Negative_regulation of Gene_expression of ALAS2	1	1	0.37	1.11	0
98	INT315585	Localization of SLC25A37	1	1	0.13	0.47	0
99	INT315581	Positive_regulation of Phosphorylation of ISCU	1	1	0.44	0.33	0
100	INT315617	Positive_regulation of Gene_expression of SLC25A37	1	1	0.10	0.39	0
101	INT315565	Negative_regulation of Gene_expression of SLC40A1	2	1	0.25	1.73	0
102	INT315631	Protein_catabolism of IREB2	1	1	0.44	0.4	0
103	INT315614	Negative_regulation of Transcription of FXN	1	1	0.25	0.82	0
104	INT315602	Binding of ISCA1	2	1	0.30	0	0
105	INT315562	Gene_expression of GLRX5	9	1	0.69	4.92	0
106	INT315587	Positive_regulation of Gene_expression of CIAO1	2	1	0.22	1.6	0
107	INT315591	Negative_regulation of Positive_regulation of SLC40A1	1	1	0.25	0.46	0
108	INT315620	Regulation of Gene_expression of GLRX5	1	1	0.40	0.5	0
109	INT315550	Transcription of GLRX5	1	1	0.53	0.66	0
110	INT315575	Transcription of SLC40A1	1	1	0.40	0.85	0
111	INT315637	Transcription of FXN	2	1	0.40	1.44	0
112	INT315634	Negative_regulation of Binding of ISCU	1	1	0.33	0.28	0
113	INT315597	Negative_regulation of ISCU	1	1	0.51	0.22	0
114	INT315600	Regulation of CIAO1	1	1	0.20	0.39	0
115	INT315571	Binding of NFS1	1	1	0.19	0	0
116	INT315613	Positive_regulation of WNT2	1	1	0.09	0.41	0
117	INT315627	Binding of GLRX5	1	1	0.33	0	0
118	INT315606	Regulation of Gene_expression of WNT2	1	1	0.08	0.84	0
119	INT315644	Negative_regulation of Transcription of DLEU1	2	1	0.21	0.64	0
120	INT315555	Binding of FXN	3	1	0.28	1.29	0
121	INT315605	Binding of ABCB7	3	1	0.33	1.84	0
122	INT315592	Positive_regulation of Gene_expression of SLC40A1	3	1	0.41	3.52	0
123	INT315640	Gene_expression of NUBP1	5	1	0.41	0.32	0
124	INT315567	Positive_regulation of Negative_regulation of CIAO1	1	1	0.22	1.29	0
125	INT315556	Positive_regulation of Binding of ALAS2	1	1	0.43	1.05	0
126	INT315623	Positive_regulation of Localization of ACO1	1	1	0.20	0.79	0
127	INT315608	Localization of NFU1	1	1	0.14	0	0
128	INT315596	Localization of ISCA2	1	1	0.11	0	0
129	INT315601	Positive_regulation of NFU1	1	1	0.22	0.13	0
130	INT315642	Negative_regulation of Gene_expression of NFU1	1	1	0.16	0.37	0
131	INT315636	Negative_regulation of ABCB7	1	1	0.38	0.17	0
132	INT315588	Regulation of ACO1	2	1	0.18	0.57	0
133	INT315570	Negative_regulation of Positive_regulation of TFRC	1	1	0.19	0.08	0
134	INT315573	Negative_regulation of Gene_expression of NFS1	2	1	0.24	0.74	0
135	INT315568	Regulation of Gene_expression of CIAO1	1	1	0.20	0.15	0
136	INT315638	Gene_expression of GLRX3	1	1	0.25	0	0
137	INT315564	Binding of NFU1	2	1	0.16	0	0
138	INT315619	Regulation of Gene_expression of NFS1	2	1	0.26	0.74	0
139	INT315607	Positive_regulation of Gene_expression of GLRX5	5	1	0.61	2.28	0
140	INT315593	Regulation of Transcription of SLC40A1	2	1	0.26	1.7	0
141	INT315549	Negative_regulation of Binding of WNT2	1	1	0.08	0.65	0
142	INT315580	Negative_regulation of Localization of SLC40A1	1	1	0.25	0.64	0
143	INT315641	Gene_expression of ISCA2	1	1	0.22	0	0
144	INT315590	Negative_regulation of Transcription of CIAO1	1	1	0.19	0.33	0
145	INT315612	Gene_expression of NFS1	5	1	0.39	1.68	0
146	INT315610	Transcription of DLEU1	2	1	0.25	0.64	0
147	INT315576	Positive_regulation of Binding of CIAO1	1	1	0.22	0.67	0
148	INT315615	Positive_regulation of ISCU	1	1	0.44	0.11	0
149	INT315589	Binding of CIAO1	1	1	0.16	0.67	0
150	INT315599	Binding of ISCA2	2	1	0.12	0	0
151	INT315639	Localization of ISCU	1	1	0.66	0	0
152	INT315560	Gene_expression of SLC19A2	3	1	0.55	1.32	0
153	INT315629	Phosphorylation of ISCU	1	1	0.71	0.33	0
154	INT315586	Gene_expression of SLC25A38	1	1	0.52	0.51	0
155	INT315604	Negative_regulation of Positive_regulation of WNT2	1	1	0.08	0.41	0
156	INT315552	Negative_regulation of GLRX5	2	1	0.38	2.17	0
157	INT315559	Negative_regulation of CIAO1	3	1	0.19	2.53	0
158	INT315618	Gene_expression of SLC25A37	1	1	0.14	0.38	0
159	INT315574	Localization of ACO1	1	1	0.30	0.79	0
160	INT315616	Positive_regulation of Gene_expression of ACO1	1	1	0.20	0.79	0
161	INT315569	Transcription of CIAO1	1	1	0.30	0.33	0
162	INT315572	Positive_regulation of ACO1	2	1	0.20	0.94	0
163	INT315566	Negative_regulation of Binding of ABCB7	1	1	0.37	0.62	0
164	INT315548	Gene_expression of NFU1	3	1	0.29	0.67	0
165	INT315579	Binding of WNT2	1	1	0.07	0.65	0
166	INT315621	Gene_expression of CIAO1	11	1	0.34	4.11	0
167	INT315553	Positive_regulation of GLRX5	1	1	0.44	0.68	0
168	INT315632	Positive_regulation of Protein_catabolism of IREB2	1	1	0.22	0.4	0
169	INT315603	Positive_regulation of Gene_expression of SLC19A2	1	1	0.41	0.48	0
170	INT315611	Binding of LYRM4	1	1	0.14	0	0
171	INT315577	Regulation of Gene_expression of NFU1	1	1	0.17	0.37	0
172	INT315558	Negative_regulation of SLC40A1	1	1	0.25	0.63	0