J:Biochemistry Research International

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT345303 MMP15 Positive_regulation of MMP13 1 1 0.00 1.18 0.58
2 INT345302 MMP15 Positive_regulation of MMP2 1 1 0.06 1.17 0.57
3 INT345308 Binding of ABCA1 and TIMP2 1 1 0.00 0.21 0.52
4 INT345306 Binding of MMP14 and TIMP2 1 1 0.04 0.21 0.48
5 INT345301 Binding of MMP14 and TIMP2 Positive_regulation of MMP2 1 1 0.02 0.21 0.48
6 INT345305 MMP14 Positive_regulation of MMP13 1 1 0.00 0.33 0.45
7 INT345304 MMP14 Positive_regulation of MMP2 1 1 0.08 0.2 0.45
8 INT345307 CXCL12 Positive_regulation of Gene_expression of MMP15 1 1 0.00 2.5 0.05
9 INT345245 Adam9 Regulation of Adam10 1 1 0.09 0.18 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
2 INT68684 Gene_expression of VEGFA 2 2371 0.78 1742.52 259.2
3 INT6665 Gene_expression of FOS 2 520 0.77 165.31 217.66
4 INT50674 Gene_expression of PTGS2 2 459 0.78 253.33 118.51
5 INT65500 Gene_expression of App 4 605 0.78 429.94 98.31
6 INT1724 Negative_regulation of ACE 2 437 0.59 315.64 74.48
7 INT1759 Gene_expression of TIMP1 2 267 0.77 133.87 59.29
8 INT73048 Gene_expression of MMP9 6 268 0.77 159.75 57.81
9 INT48232 Gene_expression of MMP1 6 245 0.78 96.31 57.72
10 INT17458 Negative_regulation of Gene_expression of FOS 2 98 0.57 36.77 55.69
11 INT26500 Gene_expression of MMP2 7 201 0.78 110.57 46.9
12 INT20492 Gene_expression of MMP12 1 89 0.76 81.36 46.12
13 INT55135 Positive_regulation of Gene_expression of PTGS2 1 137 0.70 80.32 38.46
14 INT12892 Negative_regulation of TIMP1 3 136 0.58 83.13 36.54
15 INT79060 Gene_expression of NOS2 2 116 0.78 69.25 34.84
16 INT56072 Negative_regulation of NFKB1 1 94 0.59 53.16 28.19
17 INT55737 Positive_regulation of MMP2 2 101 0.68 59.11 27.71
18 INT73047 Positive_regulation of MMP9 1 133 0.68 73.22 26.42
19 INT89662 Positive_regulation of Gene_expression of App 1 169 0.70 133.36 25.62
20 INT48235 Negative_regulation of NPEPPS 3 72 0.46 44.54 25.03
21 INT79061 Positive_regulation of NOS2 1 92 0.65 58.89 23.96
22 INT34488 Negative_regulation of MMP2 6 85 0.59 41.98 21.72
23 INT50814 Positive_regulation of Mmp2 1 72 0.68 51.37 20.42
24 INT27670 Negative_regulation of Ace 3 122 0.57 79.21 18.08
25 INT26972 Negative_regulation of Tenc1 1 57 0.57 56.71 16.87
26 INT1752 Negative_regulation of Ache 1 109 0.59 42.05 15.73
27 INT170335 Gene_expression of INCENP 1 176 0.54 91.62 15.31
28 INT5333 Gene_expression of NPEPPS 3 45 0.65 26.34 15.25
29 INT103210 Localization of MMP1 1 43 0.78 12.15 15.13
30 INT92823 Positive_regulation of Gene_expression of MMP1 1 65 0.68 25.69 14.31
31 INT72127 Protein_catabolism of MMRN1 3 68 0.52 56 14.13
32 INT1758 Positive_regulation of Gene_expression of TIMP1 1 62 0.69 31.72 13.98
33 INT190204 Positive_regulation of Gene_expression of MMP12 1 22 0.67 31.31 13.69
34 INT158124 Gene_expression of COL5A2 1 136 0.69 72.3 12.44
35 INT59080 Negative_regulation of Gene_expression of PTGS2 1 55 0.58 22.92 12.39
36 INT107916 Protein_catabolism of App 8 114 1.00 66.71 12.38
37 INT541 Positive_regulation of MBP 1 31 0.67 28.56 12.24
38 INT26973 Gene_expression of Tenc1 1 59 0.66 27.19 12
39 INT93715 Negative_regulation of MMP9 4 69 0.55 36.05 11.73
40 INT95369 Positive_regulation of Gene_expression of NOS2 1 36 0.55 25.09 11.37
41 INT89282 Regulation of MMP9 1 39 0.60 25.45 10.34
42 INT107606 Negative_regulation of MMP1 2 38 0.42 11.94 10.01
43 INT126031 Negative_regulation of Gene_expression of MMP9 2 40 0.57 22.71 9.79
44 INT26502 Negative_regulation of Gene_expression of MMP2 3 39 0.58 21.45 9.42
45 INT28312 Gene_expression of ABCA1 2 85 0.72 37.69 9.27
46 INT20664 Binding of ACE 1 60 0.48 35.27 9.16
47 INT48978 Negative_regulation of FOS 4 41 0.57 11.94 9.14
48 INT48233 Negative_regulation of Gene_expression of MMP1 5 34 0.58 12.94 9.08
49 INT195203 Binding of Tenc1 1 14 0.32 13.97 8.28
50 INT36678 Binding of TIMP1 2 33 0.36 14.99 7.87
51 INT42038 Localization of ACE 1 26 0.80 8.88 7.06
52 INT168381 Positive_regulation of Mmp3 1 24 0.58 19.12 7.03
53 INT21579 Negative_regulation of Gene_expression of TIMP1 1 25 0.57 12.41 6.94
54 INT5847 Transcription of FOS 2 31 0.69 11.11 6.41
55 INT108628 Regulation of MMP2 3 27 0.60 14.85 6.06
56 INT63822 Gene_expression of Mmp23 1 23 0.43 14.15 5.96
57 INT117189 Binding of CXCR4 1 34 0.37 24.27 5.81
58 INT94428 Negative_regulation of Gene_expression of NOS2 1 20 0.47 11.61 5.62
59 INT2848 Localization of ABCA1 3 23 0.70 10.64 4.73
60 INT17110 Gene_expression of PSMD1 1 60 0.65 19.57 4.69
61 INT107605 Gene_expression of MMP14 4 26 0.64 25.88 4.49
62 INT72703 Gene_expression of Ide 1 79 0.70 45.04 4.47
63 INT125005 Negative_regulation of SLPI 1 9 0.42 5.79 4.43
64 INT104299 Negative_regulation of Adam17 2 18 0.47 12.03 4.39
65 INT5332 Negative_regulation of Gene_expression of NPEPPS 3 11 0.04 7.79 4.29
66 INT99608 Transcription of MMP9 1 18 0.65 9.67 4.11
67 INT133312 Binding of MMP9 1 25 0.42 16.79 3.83
68 INT134786 Gene_expression of Adam10 3 17 0.68 7.61 3.29
69 INT172551 Negative_regulation of INCENP 1 38 0.07 20.83 3.14
70 INT143952 Regulation of Gene_expression of MMP9 1 14 0.53 10.16 2.73
71 INT104476 Protein_catabolism of Timp1 1 6 0.41 5.75 2.61
72 INT60440 Localization of PSMD1 1 10 0.74 3.94 2.57
73 INT129961 Regulation of Gene_expression of MMP1 1 15 0.46 4.88 2.51
74 INT74695 Gene_expression of Ace 1 41 0.73 53.33 2.33
75 INT55736 Transcription of MMP2 1 11 0.68 5.78 2.28
76 INT158123 Negative_regulation of Gene_expression of COL5A2 1 19 0.46 15.27 2.23
77 INT45646 Protein_catabolism of Ace 2 5 0.98 3.14 1.95
78 INT43084 Binding of Ace 1 10 0.46 4.7 1.93
79 INT107607 Negative_regulation of MMP14 3 10 0.37 6.05 1.83
80 INT121117 Regulation of Protein_catabolism of App 1 10 0.62 6.41 1.78
81 INT148721 Binding of PSMD1 1 13 0.31 4.78 1.76
82 INT113479 Transcription of MMP14 2 3 0.51 1.81 1.7
83 INT130332 Gene_expression of Adam17 4 14 0.50 4.84 1.56
84 INT53673 Gene_expression of Furin 1 6 0.40 1.99 1.54
85 INT302990 Protein_catabolism of MBP 2 5 0.88 3.75 1.42
86 INT215941 Gene_expression of MMP25 4 2 0.58 7 1.4
87 INT169351 Positive_regulation of Mmp23 1 5 0.03 5.55 1.34
88 INT179458 Protein_catabolism of Mmp3 1 3 0.59 3.68 1.08
89 INT96579 Negative_regulation of Negative_regulation of MMP9 1 5 0.40 4.55 1.04
90 INT96581 Negative_regulation of Negative_regulation of MMP2 1 4 0.57 3.1 1.04
91 INT345320 Gene_expression of MMP23B 2 1 0.16 1.39 1
92 INT345314 Gene_expression of MMP17 4 1 0.30 6.07 0.98
93 INT2608 Localization of GPI 1 7 0.73 4.53 0.85
94 INT173581 Gene_expression of ADAM12 1 4 0.38 1.46 0.83
95 INT187132 Negative_regulation of Binding of MMP9 1 5 0.36 3.15 0.81
96 INT230803 Regulation of Negative_regulation of Ace 1 2 0.39 1.89 0.81
97 INT88179 Negative_regulation of Transcription of FOS 2 3 0.41 0.96 0.78
98 INT144073 Positive_regulation of Gene_expression of MMP14 1 4 0.24 6.13 0.72
99 INT99899 Regulation of Mmp23 1 3 0.17 2.31 0.69
100 INT191978 Positive_regulation of Gene_expression of Ide 1 16 0.63 6.8 0.65
101 INT220082 Regulation of Protein_catabolism of MMRN1 1 2 0.04 1.23 0.65
102 INT195202 Negative_regulation of Gene_expression of Tenc1 1 7 0.24 3.76 0.62
103 INT72446 Negative_regulation of Binding of ACE 1 4 0.42 2.48 0.62
104 INT171767 Positive_regulation of Gene_expression of MMP15 1 4 0.38 4.48 0.59
105 INT210522 Protein_catabolism of Ide 1 16 0.79 7.73 0.55
106 INT88705 Localization of Ece1 5 2 0.22 2.07 0.55
107 INT210539 Binding of Ide 2 11 0.29 6.09 0.52
108 INT282919 Regulation of MMP14 1 1 0.12 1.53 0.52
109 INT228248 Gene_expression of Adam9 1 4 0.45 1.63 0.51
110 INT206530 Protein_catabolism of Mbp 2 3 0.79 0.92 0.5
111 INT345323 Protein_catabolism of MMP14 1 1 0.33 0.12 0.49
112 INT110748 Transcription of Tenc1 1 5 0.30 3.06 0.48
113 INT191968 Negative_regulation of Gene_expression of Ide 1 9 0.39 7.14 0.47
114 INT167468 Regulation of Gene_expression of ABCA1 1 5 0.52 0.08 0.43
115 INT350879 Negative_regulation of Localization of PSMD1 1 1 0.05 0.43 0.43
116 INT345317 Binding of MMP23B 1 1 0.06 1.58 0.43
117 INT209180 Transcription of ABCA1 1 4 0.47 1.09 0.39
118 INT345322 Regulation of Transcription of ABCA1 1 1 0.01 0 0.39
119 INT171765 Gene_expression of MMP15 3 3 0.59 7.64 0.36
120 INT229626 Negative_regulation of Localization of ACE 1 3 0.41 2 0.36
121 INT267844 Positive_regulation of Gene_expression of Ace 1 10 0.57 15.35 0.35
122 INT187022 Positive_regulation of Transcription of MMP9 1 3 0.45 3.27 0.34
123 INT187284 Positive_regulation of Gene_expression of Adam17 1 3 0.20 1.32 0.29
124 INT345315 Gene_expression of MMP16 2 1 0.22 4.37 0.28
125 INT175594 Gene_expression of CACYBP 1 2 0.11 0.83 0.26
126 INT284385 Positive_regulation of Localization of ABCA1 1 2 0.02 0.22 0.25
127 INT324884 Positive_regulation of Ece1 1 2 0.37 0.86 0.22
128 INT345242 Gene_expression of Folh1 1 1 0.06 0.37 0.22
129 INT345227 Gene_expression of Folh1 1 1 0.58 0.37 0.22
130 INT345319 Regulation of MMP17 1 1 0.17 1.69 0.22
131 INT345316 Regulation of Gene_expression of MMP25 1 1 0.18 1.7 0.22
132 INT345326 Regulation of MMP25 1 1 0.18 1.7 0.22
133 INT345313 Regulation of Gene_expression of MMP17 1 1 0.17 1.69 0.22
134 INT345318 Transcription of MMP24 1 1 0.21 2.09 0.18
135 INT345237 Gene_expression of Ybey 1 1 0.01 0.07 0.17
136 INT275479 Negative_regulation of Transcription of MMP2 1 2 0.25 0.43 0.16
137 INT350878 Positive_regulation of ASPM 1 1 0.02 0.16 0.16
138 INT345235 Gene_expression of Pcsk7 1 1 0.07 0.22 0.09
139 INT345240 Localization of Ece2 1 1 0.17 0.36 0.08
140 INT345234 Positive_regulation of Transcription of Adam9 1 1 0.20 0.19 0.08
141 INT345238 Transcription of Adam9 1 1 0.23 0.19 0.08
142 INT210532 Positive_regulation of Protein_catabolism of Ide 1 2 0.40 0.86 0.07
143 INT345241 Localization of Adam9 1 1 0.30 0.16 0.07
144 INT345239 Positive_regulation of Gene_expression of Adam9 1 1 0.25 0 0.05
145 INT345236 Positive_regulation of Ece2 1 1 0.11 0.25 0.04
146 INT345243 Protein_catabolism of Adam10 1 1 0.44 0 0
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