J:Biol. Reprod.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 3 0.73 0.87 14.34
2 INT145646 Binding of Scn2a1 and Scn5a 1 2 0.36 0 0.76
3 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 4 0.65 0.73 0.73
4 INT147071 NFKB1 Regulation of Gene_expression of PTGES 1 2 0.36 0.35 0.57
5 INT32662 Hps1 Negative_regulation of Localization of CGB 1 1 0.00 0 0.46
6 INT133109 Pc Positive_regulation of Pla2g6 1 1 0.34 0.28 0.28
7 INT124340 Tacr1 Positive_regulation of Tac2 1 2 0.48 0 0.27
8 INT141109 Sftpa1 Positive_regulation of Mapk1 1 2 0.77 0.65 0.27
9 INT38352 LH Regulation of Localization of Gnrhr 1 1 0.21 0 0.27
10 INT38353 Gnrh1 Regulation of Localization of Gnrhr 1 1 0.20 0 0.27
11 INT64835 Binding of Lhb and Prl 1 1 0.08 0 0.27
12 INT90280 Binding of Ppp1cc and Ppp2ca 1 1 0.34 0.22 0.22
13 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 1 0.50 0 0.22
14 INT146745 UGCG Positive_regulation of Gene_expression of PTGS2 1 1 0.23 0.1 0.16
15 INT146744 Binding of NR3C1 and PLA2G4A 1 1 0.26 0.25 0.15
16 INT141110 Negative_regulation of Sftpa1 Positive_regulation of Mapk1 1 1 0.47 0.31 0.14
17 INT141111 Sftpa1 Positive_regulation of Ptgs2 1 1 0.64 0.3 0.14
18 INT141112 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 1 0.39 0.31 0.14
19 INT141113 Sftpa1 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 1 0.46 0.32 0.14
20 INT146743 Positive_regulation of Binding of GSR and PLA2G4A 1 1 0.40 0.14 0.11
21 INT146742 Binding of GSR and PLA2G4A 1 1 0.28 0.14 0.11
22 INT147073 NFKB1 Regulation of PTGS2 1 1 0.37 0 0.11
23 INT147072 NFKB1 Regulation of PTGES 1 1 0.36 0 0.11
24 INT66856 Rln1 Positive_regulation of Localization of Mmp2 1 1 0.30 0 0.05
25 INT63243 Gnrh1 Regulation of Localization of CGA 1 1 0.00 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 1 2008 0.81 518.3 1408.65
2 INT796 Gene_expression of Penk 1 1902 0.78 275.47 1057.59
3 INT158 Localization of Prl 15 2431 0.81 378.96 952.2
4 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
5 INT2543 Positive_regulation of Calca 1 787 0.70 331.13 592.08
6 INT155 Positive_regulation of Prl 3 1233 0.70 317.93 457.82
7 INT1045 Localization of LH 31 1211 0.81 87.04 456.25
8 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
9 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
10 INT157 Positive_regulation of Localization of Prl 3 790 0.70 104.54 374.78
11 INT439 Localization of Gnrh1 20 976 0.81 100.96 363.25
12 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
13 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
14 INT162 Regulation of Prl 7 794 0.62 165.01 322.24
15 INT5979 Gene_expression of Oprd1 3 428 0.78 75.64 320.32
16 INT34869 Negative_regulation of PTGS2 1 778 0.59 366.76 319.85
17 INT477 Localization of Avp 2 813 0.81 131.58 300.4
18 INT161 Regulation of Localization of Prl 11 615 0.62 65.37 298.66
19 INT886 Gene_expression of Pomc 2 676 0.78 129.87 295.98
20 INT3579 Localization of Oxt 5 555 0.81 43.35 292.44
21 INT9659 Gene_expression of Il6 3 991 0.78 715.11 265.57
22 INT5972 Gene_expression of IL1B 1 948 0.78 510.91 263.97
23 INT1893 Localization of Gh 2 1041 0.79 340.23 256.58
24 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
25 INT5597 Gene_expression of Pdyn 1 433 0.78 62.97 235.47
26 INT1308 Localization of Pomc 6 457 0.81 66.83 217.5
27 INT767 Localization of Gnrhr 3 565 0.80 106.68 214.57
28 INT4893 Gene_expression of Tacr1 1 366 0.78 129.67 213.92
29 INT2651 Positive_regulation of Pomc 1 403 0.70 95.72 206.24
30 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
31 INT156 Negative_regulation of Prl 7 542 0.59 131.97 192.24
32 INT528 Gene_expression of Prl 7 693 0.78 217.18 192.2
33 INT2085 Positive_regulation of LH 11 441 0.70 60.15 191.02
34 INT6354 Localization of Gabrg1 1 321 0.74 41.41 186.74
35 INT1652 Regulation of Pomc 1 387 0.62 61.01 186.51
36 INT10194 Positive_regulation of IL6 2 702 0.70 600.62 183.38
37 INT159 Negative_regulation of Localization of Prl 2 416 0.59 55.34 171.8
38 INT739 Negative_regulation of POMC 2 358 0.59 102.28 166.77
39 INT5127 Localization of Lhb 28 488 0.80 50.48 162.66
40 INT2640 Gene_expression of Pomc 3 424 0.78 120.72 155.37
41 INT1044 Negative_regulation of Localization of LH 6 358 0.59 25.95 151.31
42 INT425 Localization of PRL 2 455 0.81 189.64 144.8
43 INT2379 Positive_regulation of Localization of LH 6 349 0.70 27.86 144.53
44 INT2780 Regulation of Gene_expression of Penk 1 265 0.62 32.45 143.88
45 INT1047 Negative_regulation of LH 5 314 0.59 53.71 135.89
46 INT48953 Positive_regulation of Nos2 1 486 0.70 239.85 131.87
47 INT65600 Positive_regulation of Casp3 1 376 0.70 198.44 128.03
48 INT695 Binding of POMC 2 304 0.48 56.66 126.85
49 INT416 Regulation of LH 4 253 0.62 31.48 125.55
50 INT2106 Regulation of Localization of LH 7 279 0.62 22.37 122.77
51 INT5010 Gene_expression of Calca 1 197 0.78 85.76 118.75
52 INT50674 Gene_expression of PTGS2 8 459 0.78 253.33 118.51
53 INT7395 Localization of GNRH1 11 399 0.81 62.88 117.68
54 INT1438 Localization of Pomc 2 360 0.81 101.26 116.47
55 INT62124 Gene_expression of NOS1 3 444 0.78 218.08 114.85
56 INT48593 Positive_regulation of NOS1 1 420 0.68 226.15 114.71
57 INT1793 Localization of CGA 5 379 0.81 67.38 114.69
58 INT1530 Regulation of Gh 1 382 0.61 115.96 112.47
59 INT65731 Gene_expression of Cnr1 1 234 0.78 63.82 109.34
60 INT12569 Localization of Oprd1 1 94 0.81 23.81 104.56
61 INT4742 Gene_expression of Tac1 4 177 0.78 69.99 102.66
62 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
63 INT2159 Regulation of Localization of Gnrh1 3 200 0.62 13.28 99.07
64 INT203 Positive_regulation of Pomc 2 257 0.70 90.56 92.84
65 INT2122 Negative_regulation of Localization of Gnrh1 4 226 0.59 26.92 92.04
66 INT77435 Positive_regulation of Nos2 1 343 0.70 208.49 91.43
67 INT12763 Phosphorylation of Prkcg 1 167 0.82 38.91 89.63
68 INT7885 Positive_regulation of Localization of Oxt 1 160 0.70 14.36 87.7
69 INT54571 Positive_regulation of NFKB1 3 263 0.70 138.99 87.32
70 INT4289 Positive_regulation of Localization of Gnrh1 2 202 0.70 12.3 84.01
71 INT1309 Positive_regulation of Localization of Gnrhr 1 152 0.69 24.25 81.56
72 INT1498 Gene_expression of Gh 5 521 0.75 220.84 81.16
73 INT2289 Gene_expression of PENK 3 203 0.78 55.62 79.49
74 INT2893 Localization of Oxt 10 219 0.80 28.96 79.43
75 INT24958 Gene_expression of Nkx1-1 1 106 0.74 51.29 76.88
76 INT7886 Regulation of Localization of Avp 2 146 0.62 14.53 72.99
77 INT39565 Gene_expression of Ptger2 5 424 0.75 229.28 72.68
78 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
79 INT5128 Positive_regulation of Lhb 10 232 0.69 44.23 71.26
80 INT2055 Regulation of Gnrh1 5 185 0.62 23.65 71.26
81 INT5852 Gene_expression of Penk 10 167 0.78 44.44 71.13
82 INT14624 Gene_expression of Pax3 1 100 0.38 33.22 69.47
83 INT2123 Positive_regulation of Gnrh1 4 209 0.70 24.2 68.97
84 INT65733 Positive_regulation of Cnr1 1 125 0.70 40.27 67.33
85 INT462 Regulation of Pomc 3 157 0.62 41.67 67.27
86 INT1046 Gene_expression of LH 3 180 0.77 29.75 66.87
87 INT253 Regulation of PRL 1 184 0.62 47.27 65.79
88 INT9657 Positive_regulation of Gene_expression of Il6 1 237 0.70 180.45 63.6
89 INT2056 Negative_regulation of Gnrh1 4 175 0.59 33.43 63.32
90 INT65730 Gene_expression of Cnr2 1 129 0.78 60.15 63.1
91 INT217 Negative_regulation of Th 1 134 0.59 26.83 62.63
92 INT3950 Gene_expression of Ptger2 4 293 0.77 122.28 62.42
93 INT48934 Positive_regulation of Mapk1 3 157 0.70 60.61 61.72
94 INT7884 Regulation of Localization of Oxt 1 102 0.62 7.95 61.71
95 INT1437 Negative_regulation of Pomc 1 132 0.59 35.22 60.97
96 INT39153 Positive_regulation of PTGS2 2 182 0.70 96.16 60.6
97 INT3161 Regulation of Localization of Gh 1 163 0.61 35.43 59.45
98 INT1794 Regulation of Localization of CGA 1 136 0.57 13.39 59.07
99 INT7491 Localization of Pdyn 1 80 0.81 3.94 58.77
100 INT5710 Negative_regulation of Localization of Lhb 14 146 0.57 20.51 58.33
101 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
102 INT10668 Positive_regulation of Gene_expression of Oprd1 1 61 0.69 15.21 52.12
103 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
104 INT2197 Gene_expression of Gnrh1 4 184 0.78 40.04 50.57
105 INT937 Positive_regulation of Oxt 1 195 0.70 37.82 49.3
106 INT6299 Regulation of Localization of Lhb 7 104 0.61 8.98 48.79
107 INT32718 Gene_expression of OPRD1 2 82 0.76 9.43 48.38
108 INT847 Regulation of Lhb 6 131 0.61 22.08 46.54
109 INT20345 Gene_expression of Dbi 1 136 0.78 56.41 46.2
110 INT2262 Negative_regulation of Lhb 9 142 0.59 25.47 44.81
111 INT63383 Binding of Cnr1 1 77 0.48 22.28 44.61
112 INT5130 Regulation of GNRH1 2 139 0.62 31.95 42.08
113 INT3933 Positive_regulation of PLOD1 1 128 0.70 30.76 42.03
114 INT28265 Positive_regulation of Calca 1 62 0.70 29.1 41.17
115 INT6357 Positive_regulation of Localization of Gabrg1 1 53 0.41 7.03 39.21
116 INT55135 Positive_regulation of Gene_expression of PTGS2 10 137 0.70 80.32 38.46
117 INT65125 Gene_expression of Tacr1 2 81 0.77 23.9 38.35
118 INT5039 Positive_regulation of Gal 1 67 0.68 27.97 37.36
119 INT5711 Positive_regulation of Localization of Lhb 6 90 0.70 10.92 36.76
120 INT1976 Regulation of Gene_expression of Prl 1 80 0.62 20.19 36
121 INT14559 Gene_expression of Igf1 1 254 0.78 112 34.17
122 INT109434 Phosphorylation of Mapk1 5 110 0.82 61.64 34.05
123 INT8746 Negative_regulation of Calca 1 50 0.59 21.22 33.45
124 INT3117 Regulation of Oxt 2 103 0.61 17.93 32.28
125 INT9655 Regulation of Il6 1 98 0.62 70.92 31.95
126 INT7396 Regulation of Localization of GNRH1 3 81 0.62 6.57 31.31
127 INT65960 Gene_expression of BCL2 1 352 0.78 312.03 30.73
128 INT52690 Positive_regulation of Ptgs2 1 65 0.68 39.51 30.02
129 INT64113 Positive_regulation of Gene_expression of NOS1 1 110 0.60 71.03 29.72
130 INT724 Negative_regulation of Alb 1 151 0.59 93.57 29.65
131 INT11796 Positive_regulation of Helt 1 52 0.31 11.7 29.22
132 INT91775 Gene_expression of Slc6a4 3 102 0.78 26.45 28.23
133 INT22499 Regulation of Calca 1 42 0.62 17.32 28.02
134 INT5135 Negative_regulation of GNRH1 1 106 0.58 36.63 27.71
135 INT6174 Regulation of Gene_expression of POMC 1 49 0.61 9.75 27.69
136 INT22764 Localization of Ptger2 2 81 0.64 24.38 26.77
137 INT3559 Negative_regulation of Localization of Gnrhr 2 73 0.58 18.89 26.41
138 INT20462 Binding of ESR1 1 210 0.44 102.7 26.34
139 INT2261 Gene_expression of Lhb 2 121 0.77 42.78 26.04
140 INT13415 Positive_regulation of Hpse 1 58 0.70 24.9 25.53
141 INT47075 Positive_regulation of Ptger2 1 142 0.70 78.55 25.47
142 INT7394 Positive_regulation of Localization of GNRH1 3 67 0.69 7.22 25.29
143 INT101483 Gene_expression of Lep 2 159 0.78 104.77 25.12
144 INT3028 Negative_regulation of Oxt 1 76 0.58 18.52 24.4
145 INT5988 Localization of Dbi 2 74 0.81 17.52 24.09
146 INT20003 Gene_expression of Scn2a1 2 125 0.71 8.78 23.94
147 INT5131 Gene_expression of GNRH1 1 109 0.78 28.79 23.94
148 INT16431 Localization of Lnpep 1 62 0.70 6.28 23.94
149 INT11303 Gene_expression of Avp 1 116 0.78 39.23 23.88
150 INT63419 Gene_expression of PTGES 7 109 0.77 40.83 23.67
151 INT9526 Negative_regulation of Localization of Pomc 1 41 0.58 6.93 23.3
152 INT55170 Gene_expression of NFKB1 1 97 0.77 52.75 23.04
153 INT91891 Gene_expression of Kit 3 268 0.78 158.89 22.67
154 INT4612 Positive_regulation of Localization of CGA 2 64 0.64 8.51 22.39
155 INT71047 Gene_expression of CYP19A1 1 122 0.78 68.78 22.21
156 INT11893 Positive_regulation of Ptger2 1 96 0.69 31.49 21.92
157 INT3382 Positive_regulation of Dbh 1 33 0.70 11.64 21.67
158 INT1644 Regulation of FSHR 1 77 0.55 15.62 21.49
159 INT2978 Gene_expression of Tbxa2r 3 76 0.77 28.4 21.27
160 INT73593 Gene_expression of BAX 1 173 0.76 147.81 20.94
161 INT2894 Negative_regulation of Localization of Oxt 5 43 0.58 4.59 20.85
162 INT1512 Binding of Prl 1 73 0.48 26.22 20.63
163 INT27018 Gene_expression of PTGER1 2 68 0.75 31.76 20.12
164 INT5372 Localization of LHB 7 55 0.68 9.47 19
165 INT1975 Regulation of Regulation of Prl 1 32 0.59 5.78 18.53
166 INT66857 Regulation of CCL2 1 39 0.53 28.55 18.35
167 INT14724 Negative_regulation of CYP19A1 1 233 0.59 96.56 18.26
168 INT871 Negative_regulation of Gene_expression of Prl 1 53 0.58 18.89 17.79
169 INT9656 Regulation of Gene_expression of Il6 2 57 0.62 33.3 17.71
170 INT10841 Positive_regulation of Gene_expression of Gh 1 101 0.59 45.39 16.96
171 INT19929 Negative_regulation of Positive_regulation of TNF 1 52 0.59 38.16 16.51
172 INT8530 Transcription of Penk 2 48 0.70 11.67 16.34
173 INT11335 Regulation of Ptger2 1 46 0.51 22.3 15.42
174 INT128401 Positive_regulation of Positive_regulation of Mapk1 1 39 0.70 10.88 15.38
175 INT615 Regulation of Alb 1 66 0.62 33.43 15.33
176 INT11918 Localization of CGB 3 35 0.51 8.21 15.01
177 INT5430 Gene_expression of Scn8a 2 37 0.75 4.58 14.82
178 INT11762 Regulation of Dbi 2 40 0.62 7.83 14.48
179 INT10340 Regulation of Localization of Oxt 2 30 0.60 2.55 14.3
180 INT35029 Positive_regulation of Gene_expression of Ptger2 1 66 0.43 26.37 13.99
181 INT3174 Negative_regulation of Ptger2 1 43 0.38 20.95 13.43
182 INT24956 Gene_expression of Tacr3 2 22 0.74 7.21 13.37
183 INT107033 Gene_expression of Slc37a4 4 66 0.62 27.34 12.35
184 INT91413 Negative_regulation of PTGES 1 35 0.58 17.94 12.03
185 INT26973 Gene_expression of Tenc1 5 59 0.66 27.19 12
186 INT11894 Negative_regulation of Gene_expression of Ptger2 2 47 0.55 16.95 11.59
187 INT9946 Regulation of Localization of LHB 7 27 0.52 2.47 11.08
188 INT78695 Regulation of Casp3 1 24 0.44 9.43 10.48
189 INT5854 Regulation of Gene_expression of Penk 2 22 0.61 6.91 10.03
190 INT11729 Regulation of IGF1 1 71 0.61 44.58 9.71
191 INT68960 Gene_expression of Ptger4 4 42 0.67 15.75 9.64
192 INT70134 Negative_regulation of TXK 1 124 0.23 81.96 9.59
193 INT21214 Negative_regulation of Gene_expression of PENK 1 21 0.58 9.14 9.53
194 INT78038 Gene_expression of Oxtr 4 43 0.78 18.72 9.38
195 INT11336 Gene_expression of Ptgfr 2 23 0.78 2.88 9.07
196 INT126848 Positive_regulation of Phosphorylation of Mapk1 2 30 0.50 15.94 8.34
197 INT26815 Regulation of OXT 1 15 0.46 5.38 8.31
198 INT23104 Positive_regulation of Cga 1 20 0.70 10.35 8.03
199 INT91417 Positive_regulation of PTGES 2 36 0.68 18.45 7.64
200 INT165 Regulation of HRH1 1 12 0.45 1.76 7.57
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