J:Biomed. Pharmacother.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT56134 CALCA Positive_regulation of POMC 2 1 0.71 0.72 1.68
2 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 2 0.00 1.8 1.42
3 INT58870 Binding of ap and Bgn 1 1 0.13 0 0.72
4 INT56132 CALCA Positive_regulation of Localization of POMC 1 1 0.51 0.16 0.44

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 1 2008 0.81 518.3 1408.65
2 INT158 Localization of Prl 2 2431 0.81 378.96 952.2
3 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
4 INT155 Positive_regulation of Prl 1 1233 0.70 317.93 457.82
5 INT443 Localization of POMC 2 1020 0.81 284.52 443.17
6 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
7 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
8 INT5660 Binding of Oprd1 1 477 0.48 71.86 342.06
9 INT2649 Regulation of Calca 1 433 0.62 146.05 330.95
10 INT34869 Negative_regulation of PTGS2 2 778 0.59 366.76 319.85
11 INT477 Localization of Avp 2 813 0.81 131.58 300.4
12 INT49750 Negative_regulation of CPOX 1 735 0.58 360.06 274.19
13 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
14 INT68684 Gene_expression of VEGFA 4 2371 0.78 1742.52 259.2
15 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
16 INT626 Localization of CALCA 3 289 0.81 125.39 221.15
17 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
18 INT50670 Gene_expression of CPOX 3 763 0.76 442.13 195.02
19 INT5127 Localization of Lhb 1 488 0.80 50.48 162.66
20 INT5061 Negative_regulation of Mme 1 306 0.59 51.97 136.9
21 INT5008 Localization of Calca 2 204 0.81 80.35 125.16
22 INT252 Localization of GH1 1 529 0.80 227.4 122.05
23 INT5010 Gene_expression of Calca 4 197 0.78 85.76 118.75
24 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
25 INT12569 Localization of Oprd1 2 94 0.81 23.81 104.56
26 INT914 Positive_regulation of GH1 1 292 0.69 100.7 84.91
27 INT148 Positive_regulation of Gnrhr 1 182 0.70 47.44 79.64
28 INT2055 Regulation of Gnrh1 2 185 0.62 23.65 71.26
29 INT8346 Gene_expression of Qrfp 1 136 0.70 19.49 70.21
30 INT4637 Binding of Adarb1 1 132 0.41 14.48 67.76
31 INT3375 Gene_expression of IGHE 1 535 0.77 387.47 65.46
32 INT8347 Gene_expression of SST 1 181 0.78 104.59 65.45
33 INT11937 Localization of Il6 1 228 0.81 139.83 64.39
34 INT50672 Positive_regulation of CPOX 1 205 0.44 125.93 60.06
35 INT3920 Localization of Ldha 1 241 0.81 83.08 58.72
36 INT52611 Negative_regulation of Ptgs2 2 142 0.59 66.31 52.71
37 INT5957 Positive_regulation of Cpe 1 65 0.69 21.07 51.22
38 INT921 Regulation of GH1 1 172 0.60 52.88 51.04
39 INT19775 Localization of Il1 2 183 0.78 145.5 50.91
40 INT53083 Gene_expression of Ptgs2 1 153 0.78 90.04 50.39
41 INT375 Positive_regulation of REN 1 293 0.70 152.46 47.55
42 INT28265 Positive_regulation of Calca 1 62 0.70 29.1 41.17
43 INT3971 Positive_regulation of Alb 1 175 0.70 98.46 36.45
44 INT5743 Localization of NA 1 104 0.59 14.35 35.29
45 INT1624 Gene_expression of Cea 1 212 0.76 180.44 34.21
46 INT2699 Binding of Cpe 1 40 0.48 7.07 33.64
47 INT8746 Negative_regulation of Calca 1 50 0.59 21.22 33.45
48 INT35406 Localization of Tnf 2 94 0.81 64.63 31.65
49 INT99688 Negative_regulation of Gene_expression of VEGFA 2 274 0.58 201.8 31.1
50 INT724 Negative_regulation of Alb 1 151 0.59 93.57 29.65
51 INT6855 Binding of NCOR2 2 71 0.41 15.64 28.96
52 INT2389 Regulation of PTGS1 1 86 0.61 31.23 28.95
53 INT43486 Positive_regulation of Ifng 3 52 0.69 32.71 24.77
54 INT1512 Binding of Prl 1 73 0.48 26.22 20.63
55 INT10565 Gene_expression of MRXS5 1 94 0.53 37.35 19.08
56 INT13400 Negative_regulation of Enpep 4 30 0.50 4.23 15.86
57 INT4340 Positive_regulation of Localization of Ldha 1 46 0.70 14.52 15.66
58 INT85964 Gene_expression of Pecam1 2 109 0.78 69.73 15.21
59 INT49376 Negative_regulation of Localization of Il6 1 37 0.59 12.66 14.99
60 INT109535 Gene_expression of Vegfa 2 116 0.75 84.61 14.89
61 INT40478 Negative_regulation of NCOR2 1 23 0.48 12.77 14.56
62 INT22276 Gene_expression of TBXA2R 1 65 0.77 23.22 14.21
63 INT15350 Localization of Prl 2 22 0.81 6.86 10.74
64 INT6125 Localization of Ahsp 1 35 0.78 9.17 9.42
65 INT29411 Positive_regulation of ADRB2 1 13 0.65 5.42 8.78
66 INT53573 Negative_regulation of Localization of Tnf 2 19 0.59 11.57 8.54
67 INT29229 Regulation of NCOR2 1 20 0.42 5.75 8.08
68 INT16869 Positive_regulation of Prl 1 24 0.70 15.7 7.63
69 INT6652 Negative_regulation of FPR1 1 11 0.42 5.29 7.41
70 INT16344 Gene_expression of CASP4 1 11 0.74 4.64 6.75
71 INT53572 Negative_regulation of Localization of Il1 2 18 0.40 12.78 6.7
72 INT62950 Gene_expression of NPPB 1 73 0.75 65.91 6.54
73 INT3041 Positive_regulation of MIA3 1 34 0.56 21.11 6.49
74 INT2137 Localization of Cea 1 27 0.70 19.22 6.14
75 INT11177 Localization of Ldha 1 17 0.81 5.74 6.13
76 INT4863 Positive_regulation of ap 1 22 0.37 9.13 6.11
77 INT6098 Binding of NEUROD1 1 17 0.47 3.4 5.99
78 INT12042 Regulation of MIA3 2 28 0.23 17.33 5.79
79 INT86982 Transcription of Calca 2 9 0.69 2.98 5.74
80 INT93387 Gene_expression of Sds 1 9 0.65 2.58 5.72
81 INT57064 Positive_regulation of APC 1 72 0.66 48.5 5.08
82 INT21254 Regulation of Positive_regulation of POMC 1 12 0.61 3.64 4.67
83 INT74447 Gene_expression of Vwf 1 39 0.76 21.96 4.66
84 INT15348 Positive_regulation of Localization of Prl 1 6 0.70 1.16 4.31
85 INT38005 Regulation of Localization of Prl 1 6 0.32 0.75 4.12
86 INT47372 Regulation of ap 1 12 0.18 2.14 3.76
87 INT36364 Regulation of SK 1 19 0.28 3.16 3.71
88 INT36365 Positive_regulation of SK 1 15 0.41 4.13 3.56
89 INT43085 Negative_regulation of Ide 1 28 0.39 19.96 3.45
90 INT6405 Gene_expression of Enpep 1 9 0.67 4.79 3.4
91 INT44944 Regulation of Gene_expression of MRXS5 1 9 0.24 5.85 3.33
92 INT7773 Localization of SERPINF1 1 18 0.55 8.54 3.25
93 INT114702 Gene_expression of Fgf1 1 34 0.74 17.39 2.96
94 INT111145 Negative_regulation of Positive_regulation of Ifng 1 7 0.41 2.21 2.61
95 INT15993 Regulation of FPR1 1 8 0.40 1.24 2.42
96 INT5958 Positive_regulation of Positive_regulation of Cpe 1 3 0.38 0.58 2.39
97 INT123528 Negative_regulation of Gene_expression of Vegfa 2 10 0.57 7.08 2.31
98 INT132903 Gene_expression of Cd34 1 65 0.72 33.95 2.2
99 INT19447 Positive_regulation of Positive_regulation of Prl 1 2 0.47 0.34 2.07
100 INT47371 Negative_regulation of ap 1 32 0.32 9.8 1.96
101 INT77805 Regulation of Gene_expression of Ptgs2 1 6 0.51 2.7 1.92
102 INT40479 Negative_regulation of SIGMAR1 1 6 0.52 1.26 1.88
103 INT39632 Regulation of Localization of NA 1 8 0.20 1.52 1.81
104 INT58864 Regulation of Bgn 1 2 0.11 0.79 1.63
105 INT58861 Positive_regulation of Localization of Ldha 1 2 0.25 0.1 1.26
106 INT151513 Negative_regulation of Gene_expression of Pecam1 1 8 0.37 4.73 1.22
107 INT52186 Positive_regulation of Positive_regulation of ADRB2 1 1 0.14 0 1.02
108 INT109397 Binding of Mag 1 6 0.08 4.38 0.91
109 INT109400 Localization of CCL1 1 2 0.03 2.94 0.9
110 INT58868 Positive_regulation of Negative_regulation of ap 1 3 0.35 0 0.86
111 INT104908 Binding of B4GALNT1 1 7 0.05 4.62 0.82
112 INT52187 Regulation of Binding of NEUROD1 1 1 0.44 0 0.77
113 INT58866 Regulation of Neu1 1 3 0.08 1.13 0.75
114 INT58867 Positive_regulation of Regulation of Bgn 1 1 0.20 0 0.65
115 INT63898 Gene_expression of Tbcc 1 1 0.60 0 0.45
116 INT58862 Positive_regulation of Bgn 1 3 0.34 0.21 0.44
117 INT133874 Negative_regulation of Gene_expression of Fgf1 1 2 0.24 2.82 0.36
118 INT5736 Gene_expression of Hk1 1 3 0.17 2.31 0.24
119 INT142561 Phosphorylation of NPPB 1 3 0.66 1.65 0.18
120 INT147951 Gene_expression of Idh1 1 1 0.11 0.34 0.16
121 INT147952 Gene_expression of Mdh2 1 1 0.34 0.36 0.16
122 INT133872 Gene_expression of RCC1 1 1 0.02 0.42 0.09
123 INT133873 Regulation of Gene_expression of RCC1 1 1 0.01 0.42 0.09
124 INT17491 Regulation of Gene_expression of Enpep 1 2 0.36 0.46 0.05
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