J:Bioorg. Med. Chem. Lett.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT79206	Binding of MGP and YY1	1	2	0.34	0	0.19
2	INT109464	Dmp1 Negative_regulation of Tyr	1	1	0.04	0	0.09
3	INT109465	Dmp1 Positive_regulation of Insrr	1	1	0.00	0	0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT796	Gene_expression of Penk	3	1902	0.78	275.47	1057.59
2	INT58061	Gene_expression of Trpv1	1	1117	0.78	451.54	637.59
3	INT5895	Gene_expression of Oprm1	1	525	0.78	120.67	407.29
4	INT64202	Positive_regulation of Trpv1	2	643	0.70	249.66	397.42
5	INT5979	Gene_expression of Oprd1	3	428	0.78	75.64	320.32
6	INT9381	Positive_regulation of TRPV1	6	523	0.70	187.4	276.05
7	INT1396	Binding of Penk	2	355	0.48	22.79	269.65
8	INT1212	Binding of Oprl1	1	312	0.48	28.6	225.15
9	INT1429	Gene_expression of PDYN	1	308	0.78	61.33	175.65
10	INT4768	Positive_regulation of OPRM1	1	212	0.70	31.09	164.28
11	INT6042	Binding of Oprm1	2	248	0.48	31.77	154.34
12	INT4658	Binding of OPRM1	2	188	0.48	25.96	136.24
13	INT2541	Binding of Calca	1	200	0.48	67.14	134.62
14	INT60126	Regulation of Trpv1	1	186	0.62	85.53	133.4
15	INT5906	Negative_regulation of Oprm1	1	125	0.59	19.58	101.57
16	INT6437	Binding of YY1	11	154	0.47	26.3	90.46
17	INT4153	Binding of Insrr	3	109	0.40	17.99	72.15
18	INT15613	Negative_regulation of Ptgs2	3	160	0.59	71.08	65.08
19	INT49436	Binding of TRPV1	2	145	0.48	38.35	55.08
20	INT9383	Localization of TRPV1	1	98	0.81	33.23	46.24
21	INT6979	Positive_regulation of CA2	1	206	0.67	50.79	44.97
22	INT1319	Gene_expression of Oprl1	1	65	0.78	9.34	42.41
23	INT61925	Negative_regulation of Adk	2	53	0.59	22.46	40.38
24	INT9377	Positive_regulation of Positive_regulation of TRPV1	1	43	0.70	15.81	24.47
25	INT9282	Gene_expression of HTR1B	1	48	0.75	12.15	22.94
26	INT3359	Regulation of YY1	1	32	0.60	8.19	19.2
27	INT77902	Negative_regulation of Positive_regulation of TRPV1	1	30	0.59	9.36	19.2
28	INT104493	Negative_regulation of Mapk8	2	56	0.53	27.76	16.86
29	INT59365	Gene_expression of HTR1A	1	41	0.75	16.31	16.57
30	INT57734	Binding of SLC6A4	2	36	0.48	11.94	15.42
31	INT7057	Binding of FAIM3	1	19	0.48	4.02	13.78
32	INT39046	Positive_regulation of PTGER1	1	28	0.69	18.18	13.21
33	INT1612	Regulation of Binding of Oprl1	1	19	0.62	2.34	12.45
34	INT20457	Regulation of Ptgs1	1	23	0.48	11.63	11.56
35	INT5465	Positive_regulation of CALCRL	1	25	0.49	7.24	9.8
36	INT95342	Gene_expression of GRIN2B	1	21	0.75	4.99	9.32
37	INT33209	Positive_regulation of Binding of OPRM1	1	8	0.68	0.63	8.95
38	INT77281	Negative_regulation of HIVEP1	1	132	0.49	102.78	5.36
39	INT81226	Gene_expression of Adk	1	9	0.64	9.28	4.81
40	INT85360	Positive_regulation of Pklr	2	9	0.46	0.74	4.76
41	INT12915	Gene_expression of MGP	2	18	0.75	7.53	4.15
42	INT108086	Negative_regulation of AKR1C3	3	17	0.58	7.7	3.99
43	INT24296	Binding of NPY	1	6	0.48	2.03	3.23
44	INT7387	Gene_expression of N	1	3	0.38	0.09	2.76
45	INT121909	Regulation of FAIM3	1	3	0.22	1.06	2.42
46	INT28412	Gene_expression of SUPT7L	1	6	0.75	0.79	2.12
47	INT81328	Gene_expression of sar	1	7	0.66	2.86	1.85
48	INT50568	Positive_regulation of HCA1	1	5	0.44	5.56	1.63
49	INT79252	Positive_regulation of BHLHE23	1	3	0.67	0.28	1.58
50	INT38119	Gene_expression of TUBB4A	1	6	0.65	0.74	1.21
51	INT135483	Protein_catabolism of Em	1	3	0.56	0.14	1.21
52	INT102333	Positive_regulation of Dmp1	1	5	0.58	0	0.94
53	INT114524	Binding of GRIN2B	1	3	0.36	0.44	0.74
54	INT118253	Binding of Grid1	2	1	0.33	0	0.62
55	INT130391	Positive_regulation of AKR1C3	1	4	0.50	1.7	0.47
56	INT136121	Negative_regulation of MGAT1	1	3	0.19	0.15	0.28
57	INT88993	Gene_expression of PSMB7	1	2	0.01	0.62	0.24
58	INT79253	Positive_regulation of ST3GAL4	1	3	0.61	1.2	0.23
59	INT135482	Regulation of Hfe	1	1	0.25	0	0.21
60	INT128120	Transcription of DLD	1	1	0.67	0	0.18
61	INT109463	Regulation of Dmp1	1	1	0.16	0	0.09