J:Bioorg. Med. Chem. Lett.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT79206 Binding of MGP and YY1 1 2 0.34 0 0.19
2 INT109464 Dmp1 Negative_regulation of Tyr 1 1 0.04 0 0.09
3 INT109465 Dmp1 Positive_regulation of Insrr 1 1 0.00 0 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 3 1902 0.78 275.47 1057.59
2 INT58061 Gene_expression of Trpv1 1 1117 0.78 451.54 637.59
3 INT5895 Gene_expression of Oprm1 1 525 0.78 120.67 407.29
4 INT64202 Positive_regulation of Trpv1 2 643 0.70 249.66 397.42
5 INT5979 Gene_expression of Oprd1 3 428 0.78 75.64 320.32
6 INT9381 Positive_regulation of TRPV1 6 523 0.70 187.4 276.05
7 INT1396 Binding of Penk 2 355 0.48 22.79 269.65
8 INT1212 Binding of Oprl1 1 312 0.48 28.6 225.15
9 INT1429 Gene_expression of PDYN 1 308 0.78 61.33 175.65
10 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
11 INT6042 Binding of Oprm1 2 248 0.48 31.77 154.34
12 INT4658 Binding of OPRM1 2 188 0.48 25.96 136.24
13 INT2541 Binding of Calca 1 200 0.48 67.14 134.62
14 INT60126 Regulation of Trpv1 1 186 0.62 85.53 133.4
15 INT5906 Negative_regulation of Oprm1 1 125 0.59 19.58 101.57
16 INT6437 Binding of YY1 11 154 0.47 26.3 90.46
17 INT4153 Binding of Insrr 3 109 0.40 17.99 72.15
18 INT15613 Negative_regulation of Ptgs2 3 160 0.59 71.08 65.08
19 INT49436 Binding of TRPV1 2 145 0.48 38.35 55.08
20 INT9383 Localization of TRPV1 1 98 0.81 33.23 46.24
21 INT6979 Positive_regulation of CA2 1 206 0.67 50.79 44.97
22 INT1319 Gene_expression of Oprl1 1 65 0.78 9.34 42.41
23 INT61925 Negative_regulation of Adk 2 53 0.59 22.46 40.38
24 INT9377 Positive_regulation of Positive_regulation of TRPV1 1 43 0.70 15.81 24.47
25 INT9282 Gene_expression of HTR1B 1 48 0.75 12.15 22.94
26 INT3359 Regulation of YY1 1 32 0.60 8.19 19.2
27 INT77902 Negative_regulation of Positive_regulation of TRPV1 1 30 0.59 9.36 19.2
28 INT104493 Negative_regulation of Mapk8 2 56 0.53 27.76 16.86
29 INT59365 Gene_expression of HTR1A 1 41 0.75 16.31 16.57
30 INT57734 Binding of SLC6A4 2 36 0.48 11.94 15.42
31 INT7057 Binding of FAIM3 1 19 0.48 4.02 13.78
32 INT39046 Positive_regulation of PTGER1 1 28 0.69 18.18 13.21
33 INT1612 Regulation of Binding of Oprl1 1 19 0.62 2.34 12.45
34 INT20457 Regulation of Ptgs1 1 23 0.48 11.63 11.56
35 INT5465 Positive_regulation of CALCRL 1 25 0.49 7.24 9.8
36 INT95342 Gene_expression of GRIN2B 1 21 0.75 4.99 9.32
37 INT33209 Positive_regulation of Binding of OPRM1 1 8 0.68 0.63 8.95
38 INT77281 Negative_regulation of HIVEP1 1 132 0.49 102.78 5.36
39 INT81226 Gene_expression of Adk 1 9 0.64 9.28 4.81
40 INT85360 Positive_regulation of Pklr 2 9 0.46 0.74 4.76
41 INT12915 Gene_expression of MGP 2 18 0.75 7.53 4.15
42 INT108086 Negative_regulation of AKR1C3 3 17 0.58 7.7 3.99
43 INT24296 Binding of NPY 1 6 0.48 2.03 3.23
44 INT7387 Gene_expression of N 1 3 0.38 0.09 2.76
45 INT121909 Regulation of FAIM3 1 3 0.22 1.06 2.42
46 INT28412 Gene_expression of SUPT7L 1 6 0.75 0.79 2.12
47 INT81328 Gene_expression of sar 1 7 0.66 2.86 1.85
48 INT50568 Positive_regulation of HCA1 1 5 0.44 5.56 1.63
49 INT79252 Positive_regulation of BHLHE23 1 3 0.67 0.28 1.58
50 INT38119 Gene_expression of TUBB4A 1 6 0.65 0.74 1.21
51 INT135483 Protein_catabolism of Em 1 3 0.56 0.14 1.21
52 INT102333 Positive_regulation of Dmp1 1 5 0.58 0 0.94
53 INT114524 Binding of GRIN2B 1 3 0.36 0.44 0.74
54 INT118253 Binding of Grid1 2 1 0.33 0 0.62
55 INT130391 Positive_regulation of AKR1C3 1 4 0.50 1.7 0.47
56 INT136121 Negative_regulation of MGAT1 1 3 0.19 0.15 0.28
57 INT88993 Gene_expression of PSMB7 1 2 0.01 0.62 0.24
58 INT79253 Positive_regulation of ST3GAL4 1 3 0.61 1.2 0.23
59 INT135482 Regulation of Hfe 1 1 0.25 0 0.21
60 INT128120 Transcription of DLD 1 1 0.67 0 0.18
61 INT109463 Regulation of Dmp1 1 1 0.16 0 0.09
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