J:Bone

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT56134 CALCA Positive_regulation of POMC 2 1 0.71 0.72 1.68
2 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 2 0.44 3.31 1.31
3 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 2 0.63 2.47 1.29
4 INT99292 Pth Positive_regulation of Jun 1 1 0.10 0.13 0.36
5 INT153740 TNFRSF11A Positive_regulation of Vcp 1 1 0.04 1.15 0.13
6 INT153739 TNFRSF11A Positive_regulation of Tnfrsf11b 1 1 0.05 1.14 0.13
7 INT153742 TNFRSF11A Positive_regulation of Tnfrsf11b 1 1 0.00 1.15 0.13
8 INT153738 TNFRSF11A Positive_regulation of SQSTM1 1 1 0.05 1.22 0.13
9 INT93535 PTH Negative_regulation of Gene_expression of Tnfsf11 1 1 0.19 0.22 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT76660 Gene_expression of Trpv1 2 691 0.78 329.46 386.42
2 INT2649 Regulation of Calca 3 433 0.62 146.05 330.95
3 INT5379 Gene_expression of Fos 4 656 0.78 255.5 292.54
4 INT87687 Positive_regulation of Trpv1 1 409 0.70 210.24 257.59
5 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
6 INT2541 Binding of Calca 1 200 0.48 67.14 134.62
7 INT5380 Positive_regulation of Gene_expression of Fos 5 243 0.70 105.65 131.05
8 INT1760 Gene_expression of PTGER2 3 524 0.57 226.94 96.4
9 INT87686 Positive_regulation of Gene_expression of Trpv1 2 101 0.70 72.41 69.15
10 INT17401 Gene_expression of IGF1 11 475 0.78 232.18 62.07
11 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
12 INT8528 Negative_regulation of Gene_expression of Fos 2 100 0.59 41.15 55.6
13 INT93534 Gene_expression of Tnfsf11 3 185 0.77 119.26 33.66
14 INT8746 Negative_regulation of Calca 1 50 0.59 21.22 33.45
15 INT703 Positive_regulation of Pth 3 177 0.70 127.09 27.26
16 INT9682 Positive_regulation of IGF1 2 238 0.70 120.03 26.36
17 INT1761 Positive_regulation of PTGER2 2 135 0.49 90.17 26.26
18 INT92105 Transcription of Trpv1 1 47 0.71 27.47 25.01
19 INT76743 Gene_expression of Slc6a4 1 55 0.76 13.53 24.9
20 INT288 Positive_regulation of Sct 1 88 0.70 32.83 24.5
21 INT47741 Negative_regulation of Flvcr2 1 43 0.51 5.72 23.37
22 INT8640 Positive_regulation of HSD11B1 1 332 0.67 377.84 22.36
23 INT14731 Positive_regulation of TGFB1 1 78 0.67 52.57 22.23
24 INT1561 Negative_regulation of Dnahc8 1 59 0.59 18.12 20.99
25 INT1764 Negative_regulation of Gene_expression of PTGER2 3 81 0.34 34.74 19.45
26 INT28950 Positive_regulation of Gene_expression of IGF1 1 99 0.69 46.9 16.47
27 INT1214 Gene_expression of PGE 1 70 0.72 29.07 16.22
28 INT73916 Gene_expression of Esr1 1 58 0.77 26.59 15.15
29 INT28952 Negative_regulation of Gene_expression of IGF1 3 75 0.58 41.11 12.32
30 INT1636 Gene_expression of Sct 1 58 0.77 16.14 11.57
31 INT1762 Negative_regulation of PTGER2 1 64 0.43 28.21 11.27
32 INT70816 Negative_regulation of Fos 1 32 0.58 13 11.18
33 INT93533 Positive_regulation of Tnfsf11 1 53 0.50 36.93 10.53
34 INT11729 Regulation of IGF1 1 71 0.61 44.58 9.71
35 INT93191 Gene_expression of Accn2 3 22 0.76 10.04 8.91
36 INT22083 Regulation of Pth 2 55 0.62 22.32 8.9
37 INT48725 Gene_expression of IGFBP3 1 128 0.78 78.83 8.19
38 INT93195 Negative_regulation of Accn2 1 14 0.59 7.23 6.31
39 INT84561 Binding of COL1A2 2 18 0.47 11.76 5.09
40 INT80712 Gene_expression of PTGER4 1 21 0.65 13.08 5.03
41 INT62570 Binding of Pth 2 48 0.48 26.45 4.85
42 INT16621 Negative_regulation of Esr1 1 20 0.54 8.2 4.84
43 INT93192 Transcription of Accn2 2 5 0.52 4.63 4.79
44 INT47766 Transcription of Fos 1 25 0.69 8.78 4.42
45 INT25251 Binding of Fos 1 19 0.36 7.96 3.73
46 INT99291 Transcription of Slc6a4 1 7 0.46 1.16 3.28
47 INT743 Negative_regulation of Salpa1 1 16 0.57 8.75 3.1
48 INT131187 Regulation of Gene_expression of IGF1 2 18 0.62 11.18 3.05
49 INT93531 Negative_regulation of Gene_expression of Tnfsf11 1 15 0.43 7.74 2.84
50 INT61465 Gene_expression of Acp5 1 22 0.75 7.06 2.55
51 INT9089 Positive_regulation of Ceacam1 1 17 0.69 7.09 2.49
52 INT93532 Regulation of Tnfsf11 2 14 0.42 10.75 2.39
53 INT136190 Transcription of Accn1 1 5 0.61 2.75 2.24
54 INT136192 Negative_regulation of Gene_expression of Accn2 2 1 0.35 2.44 1.71
55 INT33431 Localization of Dnahc8 1 8 0.67 3.49 1.68
56 INT67624 Gene_expression of Phex 3 3 0.26 4.15 1.67
57 INT66709 Transcription of IGF1 1 13 0.71 5.65 1.64
58 INT121970 Negative_regulation of Transcription of Fos 1 4 0.42 2.52 1.48
59 INT124817 Regulation of CAMP 1 2 0.44 1.62 1.44
60 INT49844 Negative_regulation of Bmc1 1 16 0.24 4.53 1.42
61 INT131188 Negative_regulation of Gene_expression of PTGER4 2 1 0.41 2.51 1.41
62 INT37530 Regulation of Salpa1 1 8 0.59 4.79 1.19
63 INT61466 Positive_regulation of Acp5 1 15 0.66 10.17 1.16
64 INT36179 Regulation of GLA 1 11 0.44 6.56 1.12
65 INT70602 Regulation of Phex 1 3 0.13 1.51 1.06
66 INT118373 Gene_expression of Fgf23 1 16 0.77 29.62 1.04
67 INT93194 Negative_regulation of Transcription of Accn2 1 2 0.35 1.69 1
68 INT136193 Positive_regulation of Gene_expression of Accn2 1 1 0.38 1.43 0.97
69 INT118371 Positive_regulation of Fgf23 1 15 0.69 25.34 0.85
70 INT98645 Gene_expression of FGF23 3 9 0.78 10.07 0.8
71 INT12115 Localization of VCF 1 3 0.70 2.67 0.8
72 INT93908 Negative_regulation of Dpyd 1 9 0.45 3.19 0.78
73 INT39820 Gene_expression of CALCR 2 16 0.37 4.96 0.74
74 INT131186 Negative_regulation of PTGER4 1 2 0.41 2.97 0.74
75 INT23590 Regulation of CALCR 2 4 0.26 1.05 0.71
76 INT34723 Regulation of Mbl1 1 2 0.41 2.26 0.63
77 INT85388 Positive_regulation of Bmc1 1 8 0.25 3.74 0.56
78 INT95670 Regulation of PDB1 1 4 0.60 5.59 0.55
79 INT125727 Positive_regulation of FGF23 1 5 0.69 4.04 0.53
80 INT61464 Regulation of Acp5 1 2 0.59 0.72 0.51
81 INT125728 Localization of MAMLD1 2 1 0.68 1.44 0.28
82 INT61468 Negative_regulation of CALCR 3 4 0.42 0.27 0.17
83 INT98644 Transcription of FGF23 2 1 0.41 2.83 0.17
84 INT98641 Transcription of Phex 2 1 0.23 2.89 0.17
85 INT118372 Regulation of Fgf23 1 4 0.55 3.31 0.15
86 INT125726 Localization of CANT1 1 1 0.68 0.72 0.14
87 INT125729 Positive_regulation of MAMLD1 1 1 0.49 0.72 0.14
88 INT98643 Positive_regulation of Gene_expression of FGF23 1 2 0.47 2.16 0.13
89 INT70262 Gene_expression of Pth 1 8 0.66 5.64 0.12
90 INT98642 Binding of FGF23 1 1 0.22 1.46 0.09
91 INT98640 Binding of Phex 1 1 0.13 1.44 0.09
92 INT98639 Positive_regulation of Gene_expression of Phex 1 1 0.24 1.26 0.06
93 INT61469 Transcription of CALCR 2 3 0.43 1.37 0.04
94 INT70263 Negative_regulation of Cyp39a1 1 2 0.05 0.96 0
95 INT61467 Regulation of Gene_expression of Acp5 1 1 0.59 0.06 0
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