J:Br. J. Rheumatol.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT62176	Binding of PTGS2 and Ptgs1	2	1	0.00	0.69	0.79
2	INT52730	ZNF571 Positive_regulation of TNF	1	1	0.10	0.92	0.27
3	INT59166	Binding of fc and IgG	2	1	0.00	1.23	0.17
4	INT56584	B2M Regulation of CDA	1	1	0.00	0.39	0.05
5	INT44023	Binding of Cyp27b1 and Klk1b27	1	1	0.00	0.1	0
6	INT44025	Binding of Cd86 and Cyp27b1	1	1	0.02	0.1	0
7	INT44026	Binding of Cd86 and IgG2a	1	1	0.29	0.09	0
8	INT44024	Binding of Klk1b27 and IgG2a	1	1	0.06	0.09	0
9	INT44021	Binding of Cd86 and Klk1b27	1	2	0.04	0.23	0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT50058	Negative_regulation of Cpox	1	907	0.58	426.28	428.29
2	INT9238	Gene_expression of IL6	4	1575	0.78	1135.66	424.22
3	INT6580	Negative_regulation of Ptgs1	3	929	0.59	381.53	376.26
4	INT5235	Negative_regulation of TNF	1	924	0.59	772.91	331.98
5	INT162	Regulation of Prl	2	794	0.62	165.01	322.24
6	INT34869	Negative_regulation of PTGS2	4	778	0.59	366.76	319.85
7	INT5972	Gene_expression of IL1B	3	948	0.78	510.91	263.97
8	INT16868	Gene_expression of Il6	1	807	0.78	499.48	256.57
9	INT2391	Negative_regulation of PTGS1	2	501	0.59	207.62	205.6
10	INT10194	Positive_regulation of IL6	2	702	0.70	600.62	183.38
11	INT15516	Gene_expression of Crp	2	711	0.77	615.33	173.09
12	INT1878	Binding of HLA-B	10	440	0.48	321.16	127.36
13	INT12339	Localization of IL8	1	437	0.81	251.87	117.39
14	INT3038	Gene_expression of INS	1	1583	0.78	1174.16	107.01
15	INT18009	Positive_regulation of CRP	2	518	0.70	553.03	103.74
16	INT1498	Gene_expression of Gh	2	521	0.75	220.84	81.16
17	INT749	Gene_expression of HLA-B	2	341	0.75	224.12	77.37
18	INT5056	Gene_expression of IFNG	1	216	0.78	137.52	74.57
19	INT2055	Regulation of Gnrh1	1	185	0.62	23.65	71.26
20	INT5374	Gene_expression of Esr1	1	412	0.77	263.89	67.34
21	INT462	Regulation of Pomc	2	157	0.62	41.67	67.27
22	INT15514	Negative_regulation of Crp	2	275	0.59	194.6	64.86
23	INT17401	Gene_expression of IGF1	1	475	0.78	232.18	62.07
24	INT17564	Gene_expression of Gpt	1	322	0.75	208.51	60.36
25	INT9408	Positive_regulation of Crp	1	296	0.69	242.27	57.35
26	INT4509	Gene_expression of IGG	1	426	0.76	293.69	56.64
27	INT2774	Binding of Crp	1	241	0.48	195.89	44.39
28	INT52732	Negative_regulation of CRP	2	169	0.59	138.47	40.33
29	INT3758	Gene_expression of ALB	1	326	0.78	184.65	38.75
30	INT9082	Positive_regulation of ESR1	2	238	0.69	148.51	36.69
31	INT16960	Gene_expression of Crp	3	166	0.76	116.21	34.07
32	INT10285	Binding of ADRA1D	1	102	0.47	25.82	31.11
33	INT16814	Negative_regulation of COX5A	1	74	0.57	33.72	28.63
34	INT11361	Gene_expression of SERPINE1	9	183	0.78	136.45	27.97
35	INT9682	Positive_regulation of IGF1	1	238	0.70	120.03	26.36
36	INT14700	Regulation of IFNA1	1	111	0.45	66.16	21.52
37	INT11346	Binding of Mtx1	1	39	0.41	24.88	21.21
38	INT1876	Positive_regulation of HLA-B	2	82	0.69	52.16	21.08
39	INT11161	Gene_expression of HLA-DRB1	2	121	0.78	75.33	20.96
40	INT3593	Gene_expression of ADRA1D	1	70	0.75	29.48	20.87
41	INT52457	Gene_expression of ABCB1	3	129	0.78	38.68	19.88
42	INT12265	Positive_regulation of IgG	1	168	0.63	104.89	19.76
43	INT17237	Regulation of Esr1	2	74	0.43	49.09	17.25
44	INT2120	Gene_expression of CD79A	1	159	0.78	111.69	17.16
45	INT34590	Gene_expression of ALPP	1	199	0.75	89.85	15.1
46	INT7523	Regulation of ADRA1D	1	42	0.45	11.63	14.52
47	INT1873	Gene_expression of MRAP	3	51	0.76	31.75	13.92
48	INT56651	Binding of HLA-DRB1	1	58	0.48	52.25	13.68
49	INT19399	Gene_expression of Rf	2	43	0.36	33.39	13.53
50	INT15921	Positive_regulation of Serpine1	1	85	0.68	81.24	13.4
51	INT62441	Gene_expression of ABCC1	2	56	0.78	21.01	12.93
52	INT8210	Positive_regulation of Gene_expression of INS	1	188	0.68	146.57	12.83
53	INT10585	Localization of NAGLU	2	53	0.80	23.32	12.75
54	INT12156	Positive_regulation of MET	1	43	0.67	17.75	12.64
55	INT11359	Gene_expression of PLAU	3	84	0.76	49.54	12.31
56	INT37390	Regulation of Crp	1	39	0.46	28.74	11.45
57	INT4605	Negative_regulation of Gene_expression of INS	1	220	0.58	139.66	10.75
58	INT2378	Negative_regulation of SERPINE1	3	47	0.59	34.55	9.9
59	INT59165	Binding of fc	1	67	0.36	37.51	8.68
60	INT20205	Binding of IgG	1	108	0.46	66.68	8.57
61	INT1925	Gene_expression of PLAT	1	47	0.75	34.76	7.88
62	INT17686	Negative_regulation of Hdl1	2	72	0.36	81.85	7.74
63	INT5284	Regulation of HLA-B	1	25	0.59	12.91	7.74
64	INT1973	Positive_regulation of NAGLU	1	36	0.65	14.78	7
65	INT8541	Gene_expression of Csrp1	1	42	0.76	23.72	6.9
66	INT8799	Negative_regulation of Csrp1	4	24	0.58	11.01	6.86
67	INT13520	Binding of HLA-DRB4	1	30	0.42	32.65	6.74
68	INT10610	Negative_regulation of Plg	3	22	0.40	11.81	6.74
69	INT69980	Negative_regulation of Il1rn	1	11	0.33	7.75	6.7
70	INT69985	Positive_regulation of Negative_regulation of TNF	1	21	0.50	13.26	6.31
71	INT4561	Gene_expression of PLG	1	32	0.75	17.59	6.21
72	INT19916	Gene_expression of GPHA2	2	18	0.48	9.78	6.04
73	INT34592	Positive_regulation of Gene_expression of ALPP	1	51	0.67	20.62	5.68
74	INT13170	Gene_expression of Comp	1	25	0.74	8.68	5.62
75	INT11360	Localization of SERPINE1	1	41	0.80	33.98	5.61
76	INT4342	Localization of ALPP	2	27	0.69	15.19	5.32
77	INT3163	Gene_expression of NAGLU	2	28	0.75	15.23	4.98
78	INT16621	Negative_regulation of Esr1	1	20	0.54	8.2	4.84
79	INT24741	Positive_regulation of Rf	1	16	0.17	18.23	4.75
80	INT11354	Regulation of Gene_expression of SERPINE1	4	11	0.61	8.66	4.42
81	INT19966	Positive_regulation of C9orf3	2	19	0.67	21.88	4.38
82	INT22973	Gene_expression of Col3a1	1	22	0.42	15.85	4.32
83	INT36575	Gene_expression of TNFRSF10A	1	10	0.65	10.1	4.17
84	INT45975	Positive_regulation of SAA1	1	17	0.67	19.7	4.15
85	INT14619	Positive_regulation of Localization of NAGLU	1	18	0.62	7.73	3.94
86	INT44015	Binding of Cd86	2	16	0.31	5.92	3.58
87	INT55781	Regulation of Csrp1	2	11	0.34	6.87	3.36
88	INT1924	Regulation of PLAT	1	11	0.60	6.3	3.16
89	INT16959	Positive_regulation of Binding of HLA-B	2	8	0.50	6.77	2.96
90	INT34591	Regulation of Localization of ALPP	1	5	0.53	1.81	2.86
91	INT73836	Regulation of Comp	1	4	0.19	4.2	2.79
92	INT19430	Positive_regulation of IGHA1	2	10	0.67	6.42	2.58
93	INT69981	Positive_regulation of Negative_regulation of Il1rn	1	2	0.09	3.28	2.48
94	INT11357	Negative_regulation of Gene_expression of PLAU	2	10	0.56	5.3	2.38
95	INT11353	Gene_expression of SLC3A2	2	13	0.58	7.31	2.33
96	INT71273	Positive_regulation of Comp	1	8	0.42	3.8	2.32
97	INT24740	Positive_regulation of Cd79a	1	36	0.48	14.71	2.17
98	INT38008	Positive_regulation of Gene_expression of NAGLU	2	6	0.44	6.64	2
99	INT11364	Regulation of Gene_expression of PLAU	1	4	0.58	3.23	1.92
100	INT44027	Positive_regulation of Lif	1	7	0.40	2.76	1.9
101	INT34579	Localization of IGLL1	1	7	0.69	2.63	1.89
102	INT19914	Negative_regulation of Gene_expression of GPHA2	1	3	0.34	1.21	1.86
103	INT3459	Positive_regulation of Olfr145	1	3	0.18	1.34	1.75
104	INT78938	Binding of IGFBP3	1	40	0.45	27.95	1.73
105	INT22058	Positive_regulation of Igha	1	7	0.49	5.29	1.69
106	INT45230	Regulation of CD79A	1	20	0.44	9.3	1.59
107	INT34594	Negative_regulation of Gene_expression of ALPP	1	12	0.50	5.04	1.41
108	INT31804	Positive_regulation of Asprv1	2	5	0.40	1.92	1.26
109	INT37679	Positive_regulation of HLA-DRB4	1	12	0.34	11.93	1.16
110	INT31805	Localization of LBR	1	3	0.73	1.23	1.13
111	INT59010	Positive_regulation of Regulation of Crp	1	2	0.27	2.11	1.09
112	INT19915	Regulation of Gene_expression of GPHA2	1	3	0.21	0.78	0.99
113	INT26881	Regulation of Binding of ADRA1D	1	3	0.44	1.05	0.94
114	INT11350	Regulation of GTDC2	1	2	0.25	0.61	0.91
115	INT11348	Gene_expression of Ugt3a2	2	1	0.02	0.64	0.89
116	INT76203	Positive_regulation of KRT26	1	1	0.02	1.34	0.76
117	INT76210	Positive_regulation of Krt17	1	1	0.04	1.34	0.76
118	INT11362	Regulation of Localization of SERPINE1	1	3	0.39	1.55	0.69
119	INT37141	Positive_regulation of C9	2	1	0.23	2.7	0.66
120	INT34593	Negative_regulation of Localization of ALPP	1	2	0.50	0.85	0.64
121	INT44013	Positive_regulation of Binding of Cd86	1	2	0.36	1.01	0.63
122	INT39323	Negative_regulation of Serpinf2	1	2	0.47	0.59	0.62
123	INT36576	Gene_expression of IGKV1D-22	1	4	0.07	3.17	0.59
124	INT44016	Binding of Cyp27b1	1	3	0.10	0.53	0.59
125	INT3513	Negative_regulation of Igha	1	9	0.38	7.43	0.56
126	INT37136	Transcription of Vwf	1	4	0.56	3.57	0.56
127	INT59167	Binding of CSRP1	1	7	0.35	7.33	0.55
128	INT11358	Gene_expression of PLDN	1	2	0.11	1.16	0.55
129	INT52731	Regulation of ZNF571	1	1	0.08	1.19	0.53
130	INT73834	Regulation of Ibsp	1	2	0.17	1.06	0.52
131	INT20099	Regulation of Positive_regulation of Serpine1	1	2	0.40	1.75	0.52
132	INT73835	Regulation of Gene_expression of Ibsp	1	1	0.04	0.89	0.52
133	INT73833	Gene_expression of Ibsp	1	7	0.44	1.58	0.51
134	INT11347	Positive_regulation of Gene_expression of Ugt3a2	1	1	0.01	0.3	0.51
135	INT45020	Binding of CREG1	1	2	0.47	0.91	0.5
136	INT11355	Regulation of SLC3A2	1	1	0.01	1.05	0.5
137	INT11363	Regulation of Gene_expression of PLAT	1	1	0.27	0.87	0.46
138	INT11356	Regulation of Gene_expression of SLC3A2	1	1	0.01	0.78	0.42
139	INT72720	Negative_regulation of HLA-DRB5	1	1	0.00	0.81	0.36
140	INT44019	Gene_expression of Klk1b27	4	1	0.09	0.6	0.32
141	INT72719	Positive_regulation of HLA-DRB2	1	1	0.01	0.73	0.3
142	INT44012	Phosphorylation of HLA-B	1	3	0.81	0.96	0.27
143	INT37142	Positive_regulation of Positive_regulation of C9	1	1	0.23	1.13	0.26
144	INT75822	Gene_expression of TRA@	1	2	0.65	0.34	0.24
145	INT44014	Gene_expression of Ifi27l2b	2	1	0.11	0.3	0.16
146	INT34580	Positive_regulation of Localization of IGLL1	1	1	0.43	0.36	0.14
147	INT44020	Binding of Ifi27l2b	1	1	0.06	0.25	0.1
148	INT51990	Transcription of Serpine1	1	3	0.45	2.01	0.09
149	INT44017	Regulation of Ifi27l2b	1	1	0.07	0.13	0.05
150	INT44018	Positive_regulation of Ifi27l2b	1	1	0.08	0.09	0