J:Br. J. Rheumatol.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT62176 Binding of PTGS2 and Ptgs1 2 1 0.00 0.69 0.79
2 INT52730 ZNF571 Positive_regulation of TNF 1 1 0.10 0.92 0.27
3 INT59166 Binding of fc and IgG 2 1 0.00 1.23 0.17
4 INT56584 B2M Regulation of CDA 1 1 0.00 0.39 0.05
5 INT44023 Binding of Cyp27b1 and Klk1b27 1 1 0.00 0.1 0
6 INT44025 Binding of Cd86 and Cyp27b1 1 1 0.02 0.1 0
7 INT44026 Binding of Cd86 and IgG2a 1 1 0.29 0.09 0
8 INT44024 Binding of Klk1b27 and IgG2a 1 1 0.06 0.09 0
9 INT44021 Binding of Cd86 and Klk1b27 1 2 0.04 0.23 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT50058 Negative_regulation of Cpox 1 907 0.58 426.28 428.29
2 INT9238 Gene_expression of IL6 4 1575 0.78 1135.66 424.22
3 INT6580 Negative_regulation of Ptgs1 3 929 0.59 381.53 376.26
4 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
5 INT162 Regulation of Prl 2 794 0.62 165.01 322.24
6 INT34869 Negative_regulation of PTGS2 4 778 0.59 366.76 319.85
7 INT5972 Gene_expression of IL1B 3 948 0.78 510.91 263.97
8 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
9 INT2391 Negative_regulation of PTGS1 2 501 0.59 207.62 205.6
10 INT10194 Positive_regulation of IL6 2 702 0.70 600.62 183.38
11 INT15516 Gene_expression of Crp 2 711 0.77 615.33 173.09
12 INT1878 Binding of HLA-B 10 440 0.48 321.16 127.36
13 INT12339 Localization of IL8 1 437 0.81 251.87 117.39
14 INT3038 Gene_expression of INS 1 1583 0.78 1174.16 107.01
15 INT18009 Positive_regulation of CRP 2 518 0.70 553.03 103.74
16 INT1498 Gene_expression of Gh 2 521 0.75 220.84 81.16
17 INT749 Gene_expression of HLA-B 2 341 0.75 224.12 77.37
18 INT5056 Gene_expression of IFNG 1 216 0.78 137.52 74.57
19 INT2055 Regulation of Gnrh1 1 185 0.62 23.65 71.26
20 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
21 INT462 Regulation of Pomc 2 157 0.62 41.67 67.27
22 INT15514 Negative_regulation of Crp 2 275 0.59 194.6 64.86
23 INT17401 Gene_expression of IGF1 1 475 0.78 232.18 62.07
24 INT17564 Gene_expression of Gpt 1 322 0.75 208.51 60.36
25 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
26 INT4509 Gene_expression of IGG 1 426 0.76 293.69 56.64
27 INT2774 Binding of Crp 1 241 0.48 195.89 44.39
28 INT52732 Negative_regulation of CRP 2 169 0.59 138.47 40.33
29 INT3758 Gene_expression of ALB 1 326 0.78 184.65 38.75
30 INT9082 Positive_regulation of ESR1 2 238 0.69 148.51 36.69
31 INT16960 Gene_expression of Crp 3 166 0.76 116.21 34.07
32 INT10285 Binding of ADRA1D 1 102 0.47 25.82 31.11
33 INT16814 Negative_regulation of COX5A 1 74 0.57 33.72 28.63
34 INT11361 Gene_expression of SERPINE1 9 183 0.78 136.45 27.97
35 INT9682 Positive_regulation of IGF1 1 238 0.70 120.03 26.36
36 INT14700 Regulation of IFNA1 1 111 0.45 66.16 21.52
37 INT11346 Binding of Mtx1 1 39 0.41 24.88 21.21
38 INT1876 Positive_regulation of HLA-B 2 82 0.69 52.16 21.08
39 INT11161 Gene_expression of HLA-DRB1 2 121 0.78 75.33 20.96
40 INT3593 Gene_expression of ADRA1D 1 70 0.75 29.48 20.87
41 INT52457 Gene_expression of ABCB1 3 129 0.78 38.68 19.88
42 INT12265 Positive_regulation of IgG 1 168 0.63 104.89 19.76
43 INT17237 Regulation of Esr1 2 74 0.43 49.09 17.25
44 INT2120 Gene_expression of CD79A 1 159 0.78 111.69 17.16
45 INT34590 Gene_expression of ALPP 1 199 0.75 89.85 15.1
46 INT7523 Regulation of ADRA1D 1 42 0.45 11.63 14.52
47 INT1873 Gene_expression of MRAP 3 51 0.76 31.75 13.92
48 INT56651 Binding of HLA-DRB1 1 58 0.48 52.25 13.68
49 INT19399 Gene_expression of Rf 2 43 0.36 33.39 13.53
50 INT15921 Positive_regulation of Serpine1 1 85 0.68 81.24 13.4
51 INT62441 Gene_expression of ABCC1 2 56 0.78 21.01 12.93
52 INT8210 Positive_regulation of Gene_expression of INS 1 188 0.68 146.57 12.83
53 INT10585 Localization of NAGLU 2 53 0.80 23.32 12.75
54 INT12156 Positive_regulation of MET 1 43 0.67 17.75 12.64
55 INT11359 Gene_expression of PLAU 3 84 0.76 49.54 12.31
56 INT37390 Regulation of Crp 1 39 0.46 28.74 11.45
57 INT4605 Negative_regulation of Gene_expression of INS 1 220 0.58 139.66 10.75
58 INT2378 Negative_regulation of SERPINE1 3 47 0.59 34.55 9.9
59 INT59165 Binding of fc 1 67 0.36 37.51 8.68
60 INT20205 Binding of IgG 1 108 0.46 66.68 8.57
61 INT1925 Gene_expression of PLAT 1 47 0.75 34.76 7.88
62 INT17686 Negative_regulation of Hdl1 2 72 0.36 81.85 7.74
63 INT5284 Regulation of HLA-B 1 25 0.59 12.91 7.74
64 INT1973 Positive_regulation of NAGLU 1 36 0.65 14.78 7
65 INT8541 Gene_expression of Csrp1 1 42 0.76 23.72 6.9
66 INT8799 Negative_regulation of Csrp1 4 24 0.58 11.01 6.86
67 INT13520 Binding of HLA-DRB4 1 30 0.42 32.65 6.74
68 INT10610 Negative_regulation of Plg 3 22 0.40 11.81 6.74
69 INT69980 Negative_regulation of Il1rn 1 11 0.33 7.75 6.7
70 INT69985 Positive_regulation of Negative_regulation of TNF 1 21 0.50 13.26 6.31
71 INT4561 Gene_expression of PLG 1 32 0.75 17.59 6.21
72 INT19916 Gene_expression of GPHA2 2 18 0.48 9.78 6.04
73 INT34592 Positive_regulation of Gene_expression of ALPP 1 51 0.67 20.62 5.68
74 INT13170 Gene_expression of Comp 1 25 0.74 8.68 5.62
75 INT11360 Localization of SERPINE1 1 41 0.80 33.98 5.61
76 INT4342 Localization of ALPP 2 27 0.69 15.19 5.32
77 INT3163 Gene_expression of NAGLU 2 28 0.75 15.23 4.98
78 INT16621 Negative_regulation of Esr1 1 20 0.54 8.2 4.84
79 INT24741 Positive_regulation of Rf 1 16 0.17 18.23 4.75
80 INT11354 Regulation of Gene_expression of SERPINE1 4 11 0.61 8.66 4.42
81 INT19966 Positive_regulation of C9orf3 2 19 0.67 21.88 4.38
82 INT22973 Gene_expression of Col3a1 1 22 0.42 15.85 4.32
83 INT36575 Gene_expression of TNFRSF10A 1 10 0.65 10.1 4.17
84 INT45975 Positive_regulation of SAA1 1 17 0.67 19.7 4.15
85 INT14619 Positive_regulation of Localization of NAGLU 1 18 0.62 7.73 3.94
86 INT44015 Binding of Cd86 2 16 0.31 5.92 3.58
87 INT55781 Regulation of Csrp1 2 11 0.34 6.87 3.36
88 INT1924 Regulation of PLAT 1 11 0.60 6.3 3.16
89 INT16959 Positive_regulation of Binding of HLA-B 2 8 0.50 6.77 2.96
90 INT34591 Regulation of Localization of ALPP 1 5 0.53 1.81 2.86
91 INT73836 Regulation of Comp 1 4 0.19 4.2 2.79
92 INT19430 Positive_regulation of IGHA1 2 10 0.67 6.42 2.58
93 INT69981 Positive_regulation of Negative_regulation of Il1rn 1 2 0.09 3.28 2.48
94 INT11357 Negative_regulation of Gene_expression of PLAU 2 10 0.56 5.3 2.38
95 INT11353 Gene_expression of SLC3A2 2 13 0.58 7.31 2.33
96 INT71273 Positive_regulation of Comp 1 8 0.42 3.8 2.32
97 INT24740 Positive_regulation of Cd79a 1 36 0.48 14.71 2.17
98 INT38008 Positive_regulation of Gene_expression of NAGLU 2 6 0.44 6.64 2
99 INT11364 Regulation of Gene_expression of PLAU 1 4 0.58 3.23 1.92
100 INT44027 Positive_regulation of Lif 1 7 0.40 2.76 1.9
101 INT34579 Localization of IGLL1 1 7 0.69 2.63 1.89
102 INT19914 Negative_regulation of Gene_expression of GPHA2 1 3 0.34 1.21 1.86
103 INT3459 Positive_regulation of Olfr145 1 3 0.18 1.34 1.75
104 INT78938 Binding of IGFBP3 1 40 0.45 27.95 1.73
105 INT22058 Positive_regulation of Igha 1 7 0.49 5.29 1.69
106 INT45230 Regulation of CD79A 1 20 0.44 9.3 1.59
107 INT34594 Negative_regulation of Gene_expression of ALPP 1 12 0.50 5.04 1.41
108 INT31804 Positive_regulation of Asprv1 2 5 0.40 1.92 1.26
109 INT37679 Positive_regulation of HLA-DRB4 1 12 0.34 11.93 1.16
110 INT31805 Localization of LBR 1 3 0.73 1.23 1.13
111 INT59010 Positive_regulation of Regulation of Crp 1 2 0.27 2.11 1.09
112 INT19915 Regulation of Gene_expression of GPHA2 1 3 0.21 0.78 0.99
113 INT26881 Regulation of Binding of ADRA1D 1 3 0.44 1.05 0.94
114 INT11350 Regulation of GTDC2 1 2 0.25 0.61 0.91
115 INT11348 Gene_expression of Ugt3a2 2 1 0.02 0.64 0.89
116 INT76203 Positive_regulation of KRT26 1 1 0.02 1.34 0.76
117 INT76210 Positive_regulation of Krt17 1 1 0.04 1.34 0.76
118 INT11362 Regulation of Localization of SERPINE1 1 3 0.39 1.55 0.69
119 INT37141 Positive_regulation of C9 2 1 0.23 2.7 0.66
120 INT34593 Negative_regulation of Localization of ALPP 1 2 0.50 0.85 0.64
121 INT44013 Positive_regulation of Binding of Cd86 1 2 0.36 1.01 0.63
122 INT39323 Negative_regulation of Serpinf2 1 2 0.47 0.59 0.62
123 INT36576 Gene_expression of IGKV1D-22 1 4 0.07 3.17 0.59
124 INT44016 Binding of Cyp27b1 1 3 0.10 0.53 0.59
125 INT3513 Negative_regulation of Igha 1 9 0.38 7.43 0.56
126 INT37136 Transcription of Vwf 1 4 0.56 3.57 0.56
127 INT59167 Binding of CSRP1 1 7 0.35 7.33 0.55
128 INT11358 Gene_expression of PLDN 1 2 0.11 1.16 0.55
129 INT52731 Regulation of ZNF571 1 1 0.08 1.19 0.53
130 INT73834 Regulation of Ibsp 1 2 0.17 1.06 0.52
131 INT20099 Regulation of Positive_regulation of Serpine1 1 2 0.40 1.75 0.52
132 INT73835 Regulation of Gene_expression of Ibsp 1 1 0.04 0.89 0.52
133 INT73833 Gene_expression of Ibsp 1 7 0.44 1.58 0.51
134 INT11347 Positive_regulation of Gene_expression of Ugt3a2 1 1 0.01 0.3 0.51
135 INT45020 Binding of CREG1 1 2 0.47 0.91 0.5
136 INT11355 Regulation of SLC3A2 1 1 0.01 1.05 0.5
137 INT11363 Regulation of Gene_expression of PLAT 1 1 0.27 0.87 0.46
138 INT11356 Regulation of Gene_expression of SLC3A2 1 1 0.01 0.78 0.42
139 INT72720 Negative_regulation of HLA-DRB5 1 1 0.00 0.81 0.36
140 INT44019 Gene_expression of Klk1b27 4 1 0.09 0.6 0.32
141 INT72719 Positive_regulation of HLA-DRB2 1 1 0.01 0.73 0.3
142 INT44012 Phosphorylation of HLA-B 1 3 0.81 0.96 0.27
143 INT37142 Positive_regulation of Positive_regulation of C9 1 1 0.23 1.13 0.26
144 INT75822 Gene_expression of TRA@ 1 2 0.65 0.34 0.24
145 INT44014 Gene_expression of Ifi27l2b 2 1 0.11 0.3 0.16
146 INT34580 Positive_regulation of Localization of IGLL1 1 1 0.43 0.36 0.14
147 INT44020 Binding of Ifi27l2b 1 1 0.06 0.25 0.1
148 INT51990 Transcription of Serpine1 1 3 0.45 2.01 0.09
149 INT44017 Regulation of Ifi27l2b 1 1 0.07 0.13 0.05
150 INT44018 Positive_regulation of Ifi27l2b 1 1 0.08 0.09 0
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