J:Brain

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT36999 Binding of HLA-DRB2 and TNFRSF25 1 3 0.05 3.46 0.91
2 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 1 0.01 0.42 0.66
3 INT101087 NTF3 Positive_regulation of Gene_expression of IKZF1 1 1 0.04 0.3 0.55
4 INT62055 Mbp Positive_regulation of Lta 1 1 0.07 1.4 0.51
5 INT39594 TPO Positive_regulation of CALR 1 1 0.30 0.91 0.32
6 INT10363 Binding of Tmem33 and RT1-Db1 1 1 0.00 0.92 0.21

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 2 1902 0.78 275.47 1057.59
2 INT158 Localization of Prl 1 2431 0.81 378.96 952.2
3 INT797 Regulation of Penk 2 812 0.62 111.13 542.24
4 INT155 Positive_regulation of Prl 2 1233 0.70 317.93 457.82
5 INT1395 Negative_regulation of Penk 1 537 0.59 87.33 389.81
6 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
7 INT477 Localization of Avp 3 813 0.81 131.58 300.4
8 INT9158 Gene_expression of Tnf 3 722 0.78 522.01 277.68
9 INT94450 Gene_expression of Nav1 8 359 0.78 131.85 275.46
10 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
11 INT6665 Gene_expression of FOS 1 520 0.77 165.31 217.66
12 INT48955 Gene_expression of Nos2 1 753 0.78 403.87 208.08
13 INT11313 Positive_regulation of Il6 1 526 0.70 331.27 201.59
14 INT156 Negative_regulation of Prl 1 542 0.59 131.97 192.24
15 INT528 Gene_expression of Prl 1 693 0.78 217.18 192.2
16 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
17 INT2451 Positive_regulation of Avp 1 355 0.70 102.66 147.69
18 INT2867 Gene_expression of CALCA 3 247 0.78 78.78 138.47
19 INT48953 Positive_regulation of Nos2 3 486 0.70 239.85 131.87
20 INT6323 Positive_regulation of Gabrg1 3 213 0.70 45.08 124.34
21 INT4207 Regulation of Avp 2 267 0.62 63.72 115.33
22 INT62124 Gene_expression of NOS1 1 444 0.78 218.08 114.85
23 INT48593 Positive_regulation of NOS1 2 420 0.68 226.15 114.71
24 INT5940 Negative_regulation of Avp 2 236 0.59 67.86 101.2
25 INT17459 Positive_regulation of Gene_expression of FOS 1 182 0.67 53.45 96.38
26 INT11587 Gene_expression of CSF2 4 645 0.78 544.38 93.89
27 INT48767 Negative_regulation of NOS1 3 312 0.59 154.25 90.32
28 INT10166 Localization of Tnf 1 237 0.81 153.95 88.64
29 INT4798 Gene_expression of Nts 1 169 0.77 29.56 86.04
30 INT148 Positive_regulation of Gnrhr 1 182 0.70 47.44 79.64
31 INT4358 Positive_regulation of Localization of Avp 1 195 0.70 30.79 77.58
32 INT62374 Gene_expression of NGF 3 158 0.78 77.87 76.45
33 INT49995 Positive_regulation of Gene_expression of Tnf 2 187 0.70 125.07 70.54
34 INT5993 Positive_regulation of Nts 1 122 0.70 26.82 70.45
35 INT4960 Positive_regulation of CSF2 1 285 0.70 256.73 65.73
36 INT480 Negative_regulation of Localization of Avp 1 151 0.59 27.64 63.72
37 INT19 Regulation of Gnrhr 1 131 0.62 36.4 55.66
38 INT4241 Regulation of CALCA 2 87 0.62 28.19 55.29
39 INT48642 Positive_regulation of TCEA1 1 92 0.70 24.59 53.64
40 INT771 Regulation of Nts 1 93 0.61 13.13 53.57
41 INT8490 Negative_regulation of CALCA 1 87 0.59 29.73 51.34
42 INT49105 Gene_expression of Vcam1 2 157 0.78 157.27 43.01
43 INT4004 Gene_expression of IGHG3 1 321 0.71 221.03 42.33
44 INT16261 Transcription of Bdnf 2 101 0.72 49.41 40.64
45 INT88322 Gene_expression of CCR5 1 111 0.78 77.36 39.84
46 INT103261 Positive_regulation of Nav1 4 68 0.70 24.25 39.27
47 INT111052 Positive_regulation of Gene_expression of Nav1 2 44 0.70 18.98 35.28
48 INT103262 Localization of Nav1 1 53 0.81 19.23 34.44
49 INT2732 Gene_expression of VIP 2 74 0.78 24.57 33.72
50 INT4727 Regulation of TAC1 1 60 0.47 6.74 32.83
51 INT29503 Gene_expression of Mmp2 1 95 0.77 56.92 31.68
52 INT48248 Gene_expression of Scn10a 1 38 0.78 19.3 25.05
53 INT48235 Negative_regulation of NPEPPS 1 72 0.46 44.54 25.03
54 INT96557 Binding of Bdnf 2 46 0.47 21.74 24.26
55 INT8518 Localization of Ifng 3 53 0.81 36.68 24.13
56 INT3589 Positive_regulation of SCN5A 1 101 0.57 46.01 21.73
57 INT74682 Positive_regulation of Mmp2 1 72 0.69 40.46 21.73
58 INT11161 Gene_expression of HLA-DRB1 1 121 0.78 75.33 20.96
59 INT76336 Negative_regulation of PDE5A 2 192 0.59 112.02 20.09
60 INT49103 Positive_regulation of Vcam1 1 71 0.69 59.52 19.85
61 INT7994 Gene_expression of Lta 2 113 0.67 69.81 19.59
62 INT80755 Gene_expression of CD40 1 88 0.75 53.68 17.86
63 INT32515 Negative_regulation of B4GALNT1 1 82 0.43 28.1 17.46
64 INT111050 Negative_regulation of Gene_expression of Nav1 2 23 0.58 5.97 17.06
65 INT23657 Positive_regulation of APP 1 64 0.70 39.76 16.68
66 INT10360 Positive_regulation of Ifng 1 33 0.68 21.73 15.19
67 INT10016 Negative_regulation of CD8A 1 81 0.42 56.68 13.15
68 INT30101 Regulation of Cacna1a 1 25 0.45 14.38 12.43
69 INT80756 Gene_expression of CD86 1 77 0.77 46.68 11.36
70 INT63773 Gene_expression of DRD2 1 25 0.78 10.41 10.8
71 INT74681 Positive_regulation of Gene_expression of Mmp2 1 23 0.55 15.58 10.74
72 INT76573 Negative_regulation of Vcam1 1 26 0.58 24.36 9.84
73 INT7995 Positive_regulation of Lta 2 28 0.66 14.98 9.8
74 INT17741 Gene_expression of MBP 1 67 0.78 23.67 9.65
75 INT2059 Positive_regulation of Negative_regulation of Prl 1 24 0.70 5.7 9.37
76 INT93914 Gene_expression of CD80 1 70 0.75 36.35 7.74
77 INT6335 Binding of TSPO 2 39 0.44 10.88 7.66
78 INT49104 Positive_regulation of Gene_expression of Vcam1 1 30 0.69 36.52 7.64
79 INT72523 Regulation of TCEA1 1 18 0.45 3.19 7.6
80 INT74629 Gene_expression of Mmp7 1 17 0.55 12.78 7.58
81 INT6596 Positive_regulation of HLA-DRB1 1 33 0.61 27.01 7.26
82 INT111049 Negative_regulation of Positive_regulation of Nav1 3 5 0.43 4.39 6.25
83 INT15775 Positive_regulation of Ren1 1 50 0.69 22.38 6.19
84 INT19768 Negative_regulation of LAMC2 1 11 0.57 10.54 5.32
85 INT1991 Gene_expression of Ean5 1 7 0.60 6.97 4.84
86 INT46350 Gene_expression of Msr1 1 32 0.65 29.39 4.55
87 INT64653 Binding of CD2 1 17 0.44 6.74 4.45
88 INT28667 Negative_regulation of Ean5 1 4 0.16 5.84 4.11
89 INT51819 Negative_regulation of MSMB 1 8 0.49 4.5 4
90 INT74684 Gene_expression of Mmp12 3 8 0.31 5.69 3.68
91 INT78203 Gene_expression of PMP22 2 12 0.63 7.49 3.58
92 INT88197 Binding of ZAK 3 9 0.46 6.23 3.54
93 INT111053 Positive_regulation of Positive_regulation of Nav1 1 4 0.46 2.97 3.53
94 INT66585 Gene_expression of IER3 1 13 0.63 7.39 3.48
95 INT62061 Gene_expression of TRGC1 1 32 0.69 17.43 3.37
96 INT93915 Positive_regulation of Gene_expression of CD40 1 14 0.44 12.45 3.35
97 INT66347 Gene_expression of MLL 1 29 0.65 14.82 3.18
98 INT93913 Positive_regulation of CD40 1 21 0.58 23.47 3.1
99 INT101239 Gene_expression of NTF3 3 9 0.76 5.91 2.97
100 INT62049 Transcription of Lta 5 1 0.18 6.93 2.67
101 INT19621 Positive_regulation of CD86 1 23 0.69 14 2.58
102 INT41789 Negative_regulation of Moxd2 1 6 0.57 4.03 2.49
103 INT75813 Positive_regulation of Positive_regulation of TCEA1 1 1 0.50 1.28 2.49
104 INT2731 Negative_regulation of LTBR 2 7 0.58 5.35 2.44
105 INT39394 Regulation of Ren1 1 13 0.45 4.83 2.4
106 INT37057 Gene_expression of Tlx2 3 12 0.76 7.98 2.38
107 INT39212 Binding of Ttr 1 14 0.48 9.62 2.31
108 INT64700 Binding of Nf1 1 14 0.45 15.24 2.29
109 INT5756 Gene_expression of KCNN1 2 7 0.59 1.07 2.29
110 INT27315 Positive_regulation of TPO 2 17 0.45 9.84 2.28
111 INT86999 Regulation of DYNLL1 1 5 0.44 2.85 2.18
112 INT114330 Binding of MPZ 1 21 0.32 25.58 2.14
113 INT62054 Transcription of Mbp 3 5 0.69 4.83 2.06
114 INT2645 Positive_regulation of ITPA 1 5 0.67 1.47 1.94
115 INT93912 Positive_regulation of CD80 1 11 0.56 7.01 1.88
116 INT24173 Negative_regulation of FCGR3A 2 6 0.40 2.69 1.81
117 INT101013 Regulation of HLA-A 1 7 0.33 6.7 1.8
118 INT62046 Negative_regulation of Lta 1 8 0.43 4.42 1.67
119 INT78202 Binding of GSTK1 2 17 0.31 5.44 1.66
120 INT98283 Negative_regulation of STON1 2 5 0.48 2.26 1.61
121 INT101090 Gene_expression of IKZF1 2 6 0.77 2.98 1.58
122 INT80905 Regulation of Ean5 1 1 0.15 2.08 1.54
123 INT74683 Positive_regulation of Gene_expression of Mmp12 1 3 0.23 2.02 1.41
124 INT65153 Binding of HLA-DPB1 1 5 0.34 3.29 1.4
125 INT103527 Positive_regulation of Smcp 1 5 0.41 2.25 1.26
126 INT74680 Positive_regulation of Mmp12 1 3 0.23 2.33 1.16
127 INT93916 Positive_regulation of IFNAR1 1 7 0.25 5.58 1.09
128 INT62044 Binding of Lta 1 16 0.30 7.49 1.01
129 INT62060 Positive_regulation of Gene_expression of TRGC1 1 3 0.61 4.7 0.88
130 INT76572 Negative_regulation of Taar2 1 1 0.02 1.41 0.86
131 INT88425 Negative_regulation of DYSF 1 4 0.57 4.68 0.83
132 INT101091 Regulation of IKZF1 1 3 0.09 0.3 0.79
133 INT69003 Negative_regulation of Binding of TSPO 2 4 0.03 2.78 0.69
134 INT97825 Negative_regulation of Dhodh 1 2 0.57 1.21 0.64
135 INT115138 Localization of Tlx2 1 2 0.66 2.14 0.49
136 INT78201 Regulation of MLL 1 2 0.02 0.79 0.48
137 INT62045 Positive_regulation of Negative_regulation of Lta 1 2 0.11 1.59 0.44
138 INT62047 Negative_regulation of Transcription of Lta 1 1 0.11 1.31 0.44
139 INT62048 Positive_regulation of Transcription of Lta 1 1 0.11 1.31 0.44
140 INT101088 Regulation of KCNN1 2 3 0.06 0.76 0.4
141 INT57528 Protein_catabolism of OR9A4 1 1 0.63 0.95 0.33
142 INT91692 Positive_regulation of Binding of ZAK 1 1 0.44 0.76 0.31
143 INT24172 Positive_regulation of Negative_regulation of FCGR3A 1 1 0.34 0.66 0.24
144 INT102354 Localization of TWIST1 1 3 0.75 0.17 0.15
145 INT107980 Gene_expression of Mdn1 1 1 0.12 0.89 0.15
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