J:Brain Res.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT165450 Gal Regulation of Ceacam3 1 1 0.41 0.06 1.47
2 INT169096 Hpcl1 Regulation of Gene_expression of Slc12a5 1 1 0.02 0.05 0.95
3 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 1 0.06 1.05 0.89
4 INT155084 Kiss1 Positive_regulation of Kiss1r 1 1 0.66 0.13 0.15

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 374 3083 0.78 894.43 1639.02
2 INT5200 Gene_expression of Fos 8 3083 0.78 894.43 1639.02
3 INT796 Gene_expression of Penk 194 1902 0.78 275.47 1057.59
4 INT5202 Positive_regulation of Gene_expression of Fos 155 1163 0.70 319.28 684
5 INT5202 Positive_regulation of Gene_expression of Fos 1 1163 0.70 319.28 684
6 INT58061 Gene_expression of Trpv1 21 1117 0.78 451.54 637.59
7 INT5228 Positive_regulation of Fos 119 934 0.70 209.8 503.87
8 INT5228 Positive_regulation of Fos 4 934 0.70 209.8 503.87
9 INT6056 Negative_regulation of Gene_expression of Fos 82 601 0.59 193.05 386.84
10 INT6056 Negative_regulation of Gene_expression of Fos 1 601 0.59 193.05 386.84
11 INT16260 Gene_expression of Bdnf 24 671 0.78 283.44 339.1
12 INT5979 Gene_expression of Oprd1 31 428 0.78 75.64 320.32
13 INT4941 Positive_regulation of Oprd1 24 345 0.70 74.26 304.41
14 INT477 Localization of Avp 45 813 0.81 131.58 300.4
15 INT63932 Positive_regulation of Ephb1 13 537 0.70 259.67 296.14
16 INT3579 Localization of Oxt 31 555 0.81 43.35 292.44
17 INT9158 Gene_expression of Tnf 10 722 0.78 522.01 277.68
18 INT5591 Regulation of Gene_expression of Fos 1 425 0.62 129.06 265.78
19 INT5501 Regulation of Oprd1 26 283 0.62 55.1 249.9
20 INT1902 Gene_expression of Cck 30 348 0.78 70.33 241.92
21 INT1562 Localization of Crh 43 499 0.81 126.74 236.68
22 INT5597 Gene_expression of Pdyn 39 433 0.78 62.97 235.47
23 INT1665 Positive_regulation of Pag1 53 270 0.68 186.63 229.87
24 INT11009 Phosphorylation of Creb1 29 458 0.82 111.34 221.97
25 INT6293 Gene_expression of Oprm1 15 312 0.78 48.73 215.61
26 INT22548 Positive_regulation of Casp3 23 483 0.70 258.78 213.07
27 INT16259 Positive_regulation of Bdnf 11 336 0.70 183.48 209.82
28 INT48955 Gene_expression of Nos2 9 753 0.78 403.87 208.08
29 INT798 Positive_regulation of Gene_expression of Penk 45 394 0.70 78.53 203.07
30 INT2211 Negative_regulation of Abat 17 267 0.59 66.51 200.98
31 INT94952 Positive_regulation of Mapk14 19 305 0.70 197.83 186.61
32 INT7506 Negative_regulation of Ltp 23 267 0.46 91.01 176.8
33 INT5930 Positive_regulation of Oprm1 13 221 0.70 31.19 172.93
34 INT4937 Negative_regulation of Oprd1 17 224 0.59 44.51 171.11
35 INT438 Gene_expression of Crh 33 376 0.78 159.11 169.17
36 INT438 Gene_expression of Crh 1 376 0.78 159.11 169.17
37 INT4768 Positive_regulation of OPRM1 8 212 0.70 31.09 164.28
38 INT768 Positive_regulation of Oprl1 17 179 0.70 40.05 156.93
39 INT2640 Gene_expression of Pomc 1 424 0.78 120.72 155.37
40 INT6042 Binding of Oprm1 21 248 0.48 31.77 154.34
41 INT4740 Gene_expression of Th 14 298 0.78 61.27 154.03
42 INT13353 Positive_regulation of Tnf 7 332 0.70 248.75 148.1
43 INT7628 Gene_expression of Ltp 4 273 0.77 70.21 147.87
44 INT2780 Regulation of Gene_expression of Penk 28 265 0.62 32.45 143.88
45 INT1273 Gene_expression of Avp 27 356 0.78 90.56 138.7
46 INT60126 Regulation of Trpv1 9 186 0.62 85.53 133.4
47 INT5595 Positive_regulation of Pdyn 23 223 0.70 48.37 130.14
48 INT695 Binding of POMC 9 304 0.48 56.66 126.85
49 INT92669 Gene_expression of Bdnf 7 309 0.78 178.26 116.68
50 INT1438 Localization of Pomc 2 360 0.81 101.26 116.47
51 INT62124 Gene_expression of NOS1 3 444 0.78 218.08 114.85
52 INT16253 Positive_regulation of Gene_expression of Bdnf 8 196 0.70 92.67 113.01
53 INT11011 Positive_regulation of Phosphorylation of Creb1 12 190 0.70 49.25 112.01
54 INT48923 Gene_expression of Ephb1 4 211 0.77 106.23 109.9
55 INT10272 Gene_expression of Il1b 25 194 0.78 121.02 103.03
56 INT82878 Gene_expression of Ccl2 9 201 0.78 164.95 101.35
57 INT97701 Phosphorylation of Mapk14 7 191 0.82 115.33 100.46
58 INT5587 Regulation of Fos 15 191 0.62 40.81 99.7
59 INT5587 Regulation of Fos 2 191 0.62 40.81 99.7
60 INT1351 Gene_expression of Pag1 15 131 0.57 89.48 98.76
61 INT65500 Gene_expression of App 2 605 0.78 429.94 98.31
62 INT74058 Gene_expression of Nos1 13 260 0.78 80.04 95.71
63 INT29971 Gene_expression of Oprk1 12 126 0.78 35.32 93.97
64 INT203 Positive_regulation of Pomc 3 257 0.70 90.56 92.84
65 INT74376 Gene_expression of Cnr1 3 173 0.78 73.43 89.7
66 INT4830 Binding of Trpv1 3 158 0.48 45.11 84.2
67 INT5590 Negative_regulation of Fos 2 144 0.59 40.94 81.98
68 INT8650 Gene_expression of Gal 5 152 0.78 61.97 81.72
69 INT10534 Positive_regulation of Trib3 3 209 0.60 78.75 81.48
70 INT99070 Gene_expression of Mapk14 1 147 0.78 103.99 79.59
71 INT64636 Positive_regulation of Gene_expression of Nos2 2 242 0.70 147.52 79.53
72 INT16654 Gene_expression of Insrr 6 138 0.46 58.96 75.68
73 INT10274 Positive_regulation of Il1b 7 123 0.70 79.76 73.56
74 INT31774 Positive_regulation of Vta1 2 67 0.44 14.52 71.79
75 INT49995 Positive_regulation of Gene_expression of Tnf 3 187 0.70 125.07 70.54
76 INT462 Regulation of Pomc 3 157 0.62 41.67 67.27
77 INT462 Regulation of Pomc 1 157 0.62 41.67 67.27
78 INT6824 Regulation of Gene_expression of Pdyn 16 114 0.62 9.48 66.73
79 INT7872 Positive_regulation of P9Ehs1 5 74 0.50 18.54 66.16
80 INT6486 Positive_regulation of Tnf 6 168 0.70 123.47 66.05
81 INT5941 Gene_expression of Oxt 14 164 0.76 22.63 65.47
82 INT6926 Regulation of Pag1 12 72 0.39 55.79 65.09
83 INT5573 Negative_regulation of Gene_expression of Penk 18 113 0.59 21.83 64.66
84 INT47690 Regulation of Bdnf 5 118 0.62 53.02 64.5
85 INT9304 Negative_regulation of Pag1 18 70 0.39 51.97 64.23
86 INT1437 Negative_regulation of Pomc 1 132 0.59 35.22 60.97
87 INT1536 Negative_regulation of NA 4 244 0.55 52.67 59.79
88 INT6623 Gene_expression of NA 3 231 0.78 45.78 59.36
89 INT62960 Gene_expression of P2rx2 3 149 0.77 58.31 59.16
90 INT49170 Negative_regulation of Nos1 4 116 0.59 60.66 58.87
91 INT3920 Localization of Ldha 3 241 0.81 83.08 58.72
92 INT6436 Positive_regulation of Positive_regulation of Fos 10 101 0.70 18.71 57.96
93 INT6436 Positive_regulation of Positive_regulation of Fos 1 101 0.70 18.71 57.96
94 INT6669 Negative_regulation of Positive_regulation of Fos 1 98 0.59 23.5 56.82
95 INT69876 Negative_regulation of Nfkb1 1 147 0.58 89.81 55.5
96 INT52800 Negative_regulation of Gene_expression of Tnf 1 142 0.59 92.27 55.47
97 INT82650 Gene_expression of Bcl2 1 312 0.78 211.71 55.03
98 INT6826 Transcription of Pdyn 20 130 0.71 22.19 54.88
99 INT84495 Positive_regulation of Positive_regulation of Ephb1 3 85 0.70 46.12 54.11
100 INT7800 Localization of Pag1 11 51 0.56 33.06 53.74
101 INT49017 Negative_regulation of Gene_expression of Nos2 2 169 0.59 80.64 52.67
102 INT66040 Positive_regulation of Bdnf 5 114 0.69 67.67 51.81
103 INT50334 Negative_regulation of Cnr1 7 84 0.58 30.86 51.75
104 INT83199 Gene_expression of Nos3 5 193 0.78 100.72 51.57
105 INT19488 Localization of ABAT 1 56 0.69 21.51 50.56
106 INT49520 Gene_expression of P2rx3 1 121 0.78 61.15 49.24
107 INT109430 Positive_regulation of Trpa1 1 119 0.70 44 49.14
108 INT29144 Gene_expression of Rvm 1 41 0.52 29.23 47.76
109 INT789 Positive_regulation of YY1 6 69 0.67 14.07 47.06
110 INT8152 Gene_expression of Vta1 1 40 0.58 19.9 46.28
111 INT2783 Gene_expression of Slc3a1 8 86 0.65 8.84 45.4
112 INT1726 Positive_regulation of Kitl 16 65 0.70 38.81 44.85
113 INT127013 Negative_regulation of Slc1a3 1 37 0.54 14.16 43.97
114 INT82883 Positive_regulation of Ccl2 4 105 0.69 84.96 42.27
115 INT5502 Positive_regulation of Gene_expression of Crh 5 69 0.70 43.06 42.23
116 INT9298 Positive_regulation of Gtpbp4 12 64 0.69 12.29 41.97
117 INT350 Localization of Th 10 79 0.80 10.26 41.17
118 INT66867 Gene_expression of Ceacam3 4 58 0.67 30.44 40.7
119 INT48075 Positive_regulation of Il1b 1 71 0.67 48.63 40.48
120 INT58062 Negative_regulation of Gene_expression of Trpv1 2 66 0.59 22.34 38.02
121 INT5039 Positive_regulation of Gal 3 67 0.68 27.97 37.36
122 INT14009 Gene_expression of Sst 7 66 0.77 19.6 37.3
123 INT97702 Positive_regulation of Phosphorylation of Mapk14 3 69 0.69 49.21 36.81
124 INT64558 Negative_regulation of Nos1 4 88 0.58 26.76 36.78
125 INT103172 Gene_expression of Slc12a5 3 81 0.77 39.45 36.22
126 INT12608 Regulation of CNR1 6 62 0.60 24.36 36.02
127 INT84260 Positive_regulation of Mapk8 1 124 0.69 72.84 35.98
128 INT52194 Positive_regulation of Grin1 2 83 0.69 25.09 34.76
129 INT129686 Gene_expression of FSCN1 1 46 0.15 18.91 34.47
130 INT12161 Positive_regulation of P2rx2 1 70 0.69 34.22 34.4
131 INT84170 Positive_regulation of Gene_expression of Ccl2 2 58 0.69 48.79 32.43
132 INT6053 Transcription of Fos 21 107 0.72 20.97 31.88
133 INT1159 Negative_regulation of Agt 4 133 0.59 40.14 31.67
134 INT29743 Negative_regulation of App 1 91 0.59 65.56 31.26
135 INT6277 Positive_regulation of Gene_expression of Pomc 1 76 0.70 21.45 31.09
136 INT15347 Positive_regulation of Localization of Pomc 2 81 0.70 28.1 31.01
137 INT6058 Localization of Fos 17 73 0.81 16.7 30.84
138 INT106554 Positive_regulation of Gene_expression of Bdnf 7 73 0.70 42.58 30.77
139 INT7956 Regulation of Gene_expression of Th 3 44 0.61 8.26 29.31
140 INT66868 Positive_regulation of Ceacam3 1 40 0.69 26.61 28.9
141 INT98522 Gene_expression of Accn3 6 68 0.78 26.95 28.6
142 INT82882 Localization of Ccl2 2 61 0.80 41.96 28
143 INT56053 Negative_regulation of Bdnf 1 77 0.58 64.4 26.83
144 INT32826 Positive_regulation of Gene_expression of Ltp 3 52 0.45 10.34 26.8
145 INT29107 Regulation of Oprk1 5 31 0.45 6.16 26.61
146 INT79395 Gene_expression of Twist1 3 193 0.77 100.06 26.34
147 INT10273 Positive_regulation of Gene_expression of Il1b 4 47 0.68 31.15 26.21
148 INT13415 Positive_regulation of Hpse 7 58 0.70 24.9 25.53
149 INT61953 Transcription of Nos2 2 101 0.72 46.64 25.49
150 INT74688 Regulation of Nos1 6 55 0.62 22.16 25.3
151 INT48248 Gene_expression of Scn10a 4 38 0.78 19.3 25.05
152 INT74377 Regulation of Cnr1 2 38 0.59 16.93 24.77
153 INT5596 Negative_regulation of Gene_expression of Pdyn 6 41 0.59 5.34 24.36
154 INT12475 Gene_expression of OPRL1 3 35 0.77 3.63 23.11
155 INT11077 Positive_regulation of Htr3a 4 63 0.67 15.61 22.7
156 INT20575 Gene_expression of Akr1d1 1 48 0.57 6.2 22.5
157 INT70504 Regulation of Gene_expression of NOS1 2 30 0.51 21.72 21.72
158 INT99068 Gene_expression of Mapk8 1 62 0.78 33.57 21.25
159 INT103169 Negative_regulation of Slc12a5 1 38 0.58 27.75 20.81
160 INT137767 Gene_expression of Eae1 1 74 0.34 89.32 20.48
161 INT125411 Negative_regulation of Phosphorylation of Mapk14 2 31 0.57 18.55 19.98
162 INT104527 Binding of FSCN1 1 18 0.23 14.75 19.6
163 INT65502 Regulation of App 1 77 0.62 52.05 19.44
164 INT124670 Gene_expression of Grik1 1 53 0.77 4.83 19.13
165 INT93734 Positive_regulation of Gene_expression of Bcl2 1 76 0.70 61.95 18.46
166 INT12575 Regulation of Hpse 3 33 0.59 17.7 18.45
167 INT84171 Negative_regulation of Gene_expression of Ccl2 3 30 0.58 26.37 18.28
168 INT106556 Negative_regulation of Gene_expression of Bdnf 1 42 0.59 34.71 17.64
169 INT86790 Gene_expression of P2rx6 3 34 0.74 14.04 15.92
170 INT7952 Localization of Slc3a1 3 32 0.81 1.28 15.69
171 INT91285 Negative_regulation of P2rx2 1 29 0.57 12.74 15.48
172 INT2843 Gene_expression of Epo 6 100 0.78 62.01 14.66
173 INT151120 Negative_regulation of Tlr4 1 18 0.59 21.09 14.46
174 INT7469 Positive_regulation of Gene_expression of Oxt 3 18 0.59 4.7 14.36
175 INT53070 Regulation of Rtn4 11 15 0.22 9.35 13.77
176 INT29170 Negative_regulation of Gene_expression of Il1b 4 25 0.59 16.36 13.68
177 INT9231 Binding of Htr3a 2 27 0.47 7.29 13.04
178 INT18372 Positive_regulation of Transcription of Pdyn 6 30 0.69 2.48 12.83
179 INT78234 Positive_regulation of Gene_expression of P2rx2 1 18 0.69 12.86 12.75
180 INT12156 Positive_regulation of MET 3 43 0.67 17.75 12.64
181 INT63104 Negative_regulation of CALCRL 2 29 0.37 13.62 12.42
182 INT99587 Positive_regulation of Gene_expression of Oprk1 2 15 0.57 5.26 12.39
183 INT76428 Gene_expression of Sstr2 8 24 0.76 6.09 12.32
184 INT72804 Negative_regulation of OPRL1 3 16 0.43 1.79 12.14
185 INT6051 Positive_regulation of Transcription of Fos 4 27 0.69 6.3 11.48
186 INT21934 Negative_regulation of Negative_regulation of Pag1 4 11 0.39 7.91 11.37
187 INT64225 Positive_regulation of Localization of ABAT 1 15 0.60 4.46 11.28
188 INT1436 Negative_regulation of Localization of Pomc 2 41 0.58 10.85 11.26
189 INT118742 Positive_regulation of Tlr4 1 32 0.69 27.55 11.09
190 INT60434 Negative_regulation of Positive_regulation of Tnf 1 20 0.46 10.01 10.64
191 INT78556 Gene_expression of PNOC 7 11 0.76 2.93 10.58
192 INT90114 Regulation of Gene_expression of Nos1 3 18 0.62 6.38 10.52
193 INT41627 Gene_expression of Nqo1 6 33 0.65 4.58 10.48
194 INT85844 Regulation of Gdnf 1 18 0.50 11.08 10.43
195 INT28857 Negative_regulation of Positive_regulation of Pag1 6 11 0.30 8.46 10.19
196 INT77877 Regulation of P9Ehs1 2 13 0.38 3.31 10.04
197 INT49474 Gene_expression of Hpse 3 24 0.55 20.11 10.03
198 INT33957 Positive_regulation of OPRL1 1 14 0.68 2.89 9.72
199 INT105304 Negative_regulation of Gene_expression of P2rx2 2 11 0.28 11.07 9.53
200 INT69528 Regulation of Gene_expression of Oprk1 3 10 0.45 4.27 8.84
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