J:Brain Res. Dev. Brain Res.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9546 Binding of Adarb1 and Penk 5 1 0.03 0 5.1
2 INT9014 Binding of Npy and Penk 1 1 0.37 0 0.93
3 INT48999 Penk Regulation of Nts 1 1 0.28 0 0.66
4 INT69109 Acot1 Regulation of Gene_expression of Serpine2 1 1 0.04 0 0.4
5 INT18125 Binding of OPRM1 and Penk 1 2 0.54 0 0.4

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 5 3083 0.78 894.43 1639.02
2 INT796 Gene_expression of Penk 47 1902 0.78 275.47 1057.59
3 INT158 Localization of Prl 1 2431 0.81 378.96 952.2
4 INT5202 Positive_regulation of Gene_expression of Fos 3 1163 0.70 319.28 684
5 INT292 Localization of Penk 3 876 0.81 88.44 669.14
6 INT728 Positive_regulation of Penk 12 1068 0.70 186.9 636.87
7 INT797 Regulation of Penk 13 812 0.62 111.13 542.24
8 INT5228 Positive_regulation of Fos 4 934 0.70 209.8 503.87
9 INT443 Localization of POMC 1 1020 0.81 284.52 443.17
10 INT5895 Gene_expression of Oprm1 2 525 0.78 120.67 407.29
11 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
12 INT1395 Negative_regulation of Penk 9 537 0.59 87.33 389.81
13 INT6056 Negative_regulation of Gene_expression of Fos 2 601 0.59 193.05 386.84
14 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
15 INT6580 Negative_regulation of Ptgs1 1 929 0.59 381.53 376.26
16 INT5660 Binding of Oprd1 3 477 0.48 71.86 342.06
17 INT876 Localization of Gh1 4 843 0.80 67.75 340.82
18 INT2649 Regulation of Calca 2 433 0.62 146.05 330.95
19 INT162 Regulation of Prl 1 794 0.62 165.01 322.24
20 INT5979 Gene_expression of Oprd1 10 428 0.78 75.64 320.32
21 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
22 INT1352 Localization of Acot1 16 728 0.80 73.01 296.01
23 INT886 Gene_expression of Pomc 4 676 0.78 129.87 295.98
24 INT1396 Binding of Penk 2 355 0.48 22.79 269.65
25 INT2909 Positive_regulation of Abat 5 334 0.70 62.1 256.43
26 INT5501 Regulation of Oprd1 2 283 0.62 55.1 249.9
27 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
28 INT5597 Gene_expression of Pdyn 7 433 0.78 62.97 235.47
29 INT1212 Binding of Oprl1 5 312 0.48 28.6 225.15
30 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
31 INT2651 Positive_regulation of Pomc 1 403 0.70 95.72 206.24
32 INT798 Positive_regulation of Gene_expression of Penk 10 394 0.70 78.53 203.07
33 INT24326 Gene_expression of Ngf 1 346 0.78 218.67 184.71
34 INT4803 Transcription of Penk 18 435 0.72 59.09 182.4
35 INT1429 Gene_expression of PDYN 1 308 0.78 61.33 175.65
36 INT21185 Binding of Ptprg 11 213 0.47 13.49 157.75
37 INT768 Positive_regulation of Oprl1 1 179 0.70 40.05 156.93
38 INT1303 Negative_regulation of Npr1 2 278 0.55 35.1 156.78
39 INT6042 Binding of Oprm1 2 248 0.48 31.77 154.34
40 INT4740 Gene_expression of Th 4 298 0.78 61.27 154.03
41 INT2910 Regulation of Abat 1 169 0.62 36.95 153.53
42 INT880 Positive_regulation of Localization of Gh1 1 304 0.70 14.79 150.23
43 INT2780 Regulation of Gene_expression of Penk 4 265 0.62 32.45 143.88
44 INT1414 Regulation of Oprl1 1 169 0.62 32.05 139.99
45 INT1273 Gene_expression of Avp 5 356 0.78 90.56 138.7
46 INT5595 Positive_regulation of Pdyn 1 223 0.70 48.37 130.14
47 INT1614 Gene_expression of Oprl1 7 164 0.78 31.43 127.74
48 INT5842 Gene_expression of Gfap 1 372 0.78 153.71 127.71
49 INT5931 Regulation of Oprm1 1 149 0.62 18.15 125.93
50 INT4259 Positive_regulation of Npr1 1 262 0.70 49.37 123.11
51 INT14151 Gene_expression of Casp3 1 311 0.78 140.26 120.68
52 INT218 Positive_regulation of Th 2 245 0.70 40.5 120.1
53 INT12501 Positive_regulation of Adarb1 1 166 0.58 36.94 118.92
54 INT5010 Gene_expression of Calca 5 197 0.78 85.76 118.75
55 INT62124 Gene_expression of NOS1 1 444 0.78 218.08 114.85
56 INT1793 Localization of CGA 1 379 0.81 67.38 114.69
57 INT7362 Gene_expression of Sst 2 185 0.78 41.73 111.37
58 INT8413 Gene_expression of Ptgs1 1 248 0.78 110.17 108.58
59 INT4742 Gene_expression of Tac1 2 177 0.78 69.99 102.66
60 INT5906 Negative_regulation of Oprm1 2 125 0.59 19.58 101.57
61 INT5587 Regulation of Fos 1 191 0.62 40.81 99.7
62 INT1351 Gene_expression of Pag1 1 131 0.57 89.48 98.76
63 INT1281 Negative_regulation of Maoa 1 203 0.59 22.47 91.66
64 INT48767 Negative_regulation of NOS1 1 312 0.59 154.25 90.32
65 INT4798 Gene_expression of Nts 1 169 0.77 29.56 86.04
66 INT3766 Positive_regulation of Localization of Acot1 1 192 0.69 21.8 85.35
67 INT875 Regulation of Localization of Gh1 2 166 0.62 12.87 84.97
68 INT4857 Regulation of Tacr1 1 115 0.62 39.01 84.52
69 INT2289 Gene_expression of PENK 1 203 0.78 55.62 79.49
70 INT1335 Negative_regulation of Oprl1 3 123 0.59 18.02 77.13
71 INT1353 Negative_regulation of Localization of Acot1 2 153 0.53 15.05 75.17
72 INT5593 Positive_regulation of Gene_expression of Pdyn 1 114 0.70 29.1 74.46
73 INT1080 Negative_regulation of Ache 6 343 0.59 108.51 72.4
74 INT8962 Gene_expression of Cpe 1 110 0.71 39.67 71.67
75 INT5852 Gene_expression of Penk 1 167 0.78 44.44 71.13
76 INT8346 Gene_expression of Qrfp 4 136 0.70 19.49 70.21
77 INT462 Regulation of Pomc 1 157 0.62 41.67 67.27
78 INT6176 Positive_regulation of Htr1a 1 117 0.67 28.23 66.17
79 INT5941 Gene_expression of Oxt 4 164 0.76 22.63 65.47
80 INT13286 Gene_expression of Ca2 1 317 0.67 71.58 65.01
81 INT5573 Negative_regulation of Gene_expression of Penk 3 113 0.59 21.83 64.66
82 INT6894 Gene_expression of CNR1 6 168 0.78 74.07 62.84
83 INT5095 Localization of Ghrh 2 185 0.81 28.09 62.08
84 INT1437 Negative_regulation of Pomc 1 132 0.59 35.22 60.97
85 INT1536 Negative_regulation of NA 1 244 0.55 52.67 59.79
86 INT1794 Regulation of Localization of CGA 2 136 0.57 13.39 59.07
87 INT5356 Positive_regulation of FOS 4 153 0.69 54.21 56.74
88 INT1510 Binding of PDYN 1 94 0.48 4.68 56.44
89 INT647 Gene_expression of SGCG 1 211 0.75 78.46 55.82
90 INT1782 Regulation of Gh1 1 125 0.62 22 55.74
91 INT19 Regulation of Gnrhr 1 131 0.62 36.4 55.66
92 INT2421 Positive_regulation of Positive_regulation of Penk 1 97 0.69 13.38 55.32
93 INT6826 Transcription of Pdyn 7 130 0.71 22.19 54.88
94 INT5759 Positive_regulation of Ptgs1 1 127 0.69 53.45 53.04
95 INT1032 Regulation of Ca2 1 202 0.52 54.91 53.03
96 INT1487 Regulation of Cpe 3 68 0.62 10.24 52.91
97 INT10668 Positive_regulation of Gene_expression of Oprd1 1 61 0.69 15.21 52.12
98 INT22546 Positive_regulation of Gene_expression of Casp3 1 97 0.70 47.89 51.92
99 INT8690 Localization of Tac1 1 71 0.80 22.98 50.75
100 INT4985 Positive_regulation of Tac1 1 81 0.69 35.79 50.67
101 INT7287 Positive_regulation of Transcription of Penk 2 103 0.70 19.81 50.37
102 INT7059 Regulation of Adra2a 1 89 0.62 18.24 48.43
103 INT8713 Regulation of Tac1 1 56 0.60 25.29 45.94
104 INT4776 Localization of TAC1 1 82 0.78 16.89 45.21
105 INT28265 Positive_regulation of Calca 4 62 0.70 29.1 41.17
106 INT72011 Positive_regulation of Binding of Ptprg 10 42 0.50 2.72 39.89
107 INT2782 Regulation of Gene_expression of Pomc 1 75 0.62 15.04 38.97
108 INT3188 Regulation of Localization of Acot1 1 84 0.59 8.94 38.56
109 INT4449 Positive_regulation of NA 2 179 0.55 40.26 37.82
110 INT81037 Negative_regulation of Slc6a3 1 70 0.59 15.31 37.01
111 INT1354 Negative_regulation of Acot1 1 87 0.43 15.01 36.44
112 INT12608 Regulation of CNR1 3 62 0.60 24.36 36.02
113 INT7326 Transcription of Th 3 83 0.72 13.5 35.33
114 INT7608 Positive_regulation of Adra2a 1 66 0.70 17.81 35.15
115 INT52194 Positive_regulation of Grin1 1 83 0.69 25.09 34.76
116 INT7286 Regulation of Transcription of Penk 5 81 0.62 9.25 33.45
117 INT1711 Negative_regulation of Positive_regulation of Penk 1 54 0.59 6.55 32.42
118 INT6683 Gene_expression of Drd2 2 64 0.78 11.31 32.28
119 INT6053 Transcription of Fos 1 107 0.72 20.97 31.88
120 INT7787 Positive_regulation of Akr1d1 1 52 0.66 3.55 31.71
121 INT10285 Binding of ADRA1D 1 102 0.47 25.82 31.11
122 INT6558 Positive_regulation of Gene_expression of Th 2 56 0.70 9.64 30.89
123 INT29477 Transcription of Oprl1 8 52 0.72 5.05 30.52
124 INT1079 Positive_regulation of Ache 2 104 0.70 23.52 30.28
125 INT7956 Regulation of Gene_expression of Th 1 44 0.61 8.26 29.31
126 INT15000 Transcription of Oprd1 3 32 0.72 5.7 29.22
127 INT5440 Negative_regulation of Ina 1 85 0.58 10.52 28.98
128 INT1616 Regulation of Gad1 1 46 0.61 10.2 28.64
129 INT7035 Regulation of CGA 1 87 0.45 29.04 28.45
130 INT22499 Regulation of Calca 1 42 0.62 17.32 28.02
131 INT7779 Negative_regulation of Adra2a 1 47 0.58 9.45 28
132 INT21186 Negative_regulation of Binding of Ptprg 3 28 0.44 1.78 27.04
133 INT2569 Gene_expression of Ache 5 120 0.78 26.29 26.89
134 INT5232 Negative_regulation of Enpep 1 56 0.57 3.25 26.7
135 INT4735 Gene_expression of Acot1 1 80 0.71 13.22 26.68
136 INT605 Regulation of Acot1 2 61 0.62 10.7 26.34
137 INT28336 Positive_regulation of Pax3 1 37 0.33 20.94 25.66
138 INT13334 Gene_expression of Drd1a 1 43 0.62 7.73 24.43
139 INT48240 Binding of Ngf 2 46 0.46 23.51 24.42
140 INT5592 Regulation of Regulation of Penk 2 36 0.62 4.37 24.02
141 INT30386 Negative_regulation of OPRD1 2 33 0.52 4.34 23.06
142 INT5511 Negative_regulation of Gene_expression of Pomc 1 47 0.59 12.08 23.02
143 INT29704 Regulation of Casp3 1 51 0.56 22.13 22.79
144 INT19949 Regulation of Positive_regulation of Fos 1 36 0.60 6.11 22.05
145 INT1703 Regulation of pCA 1 52 0.52 23.65 20.6
146 INT10442 Negative_regulation of CNR1 1 47 0.59 20.88 20.2
147 INT7017 Regulation of Npr1 2 45 0.52 3.38 20.05
148 INT14436 Gene_expression of Dbh 1 42 0.72 9.9 19.85
149 INT11243 Localization of NPY 1 33 0.78 11.18 19.24
150 INT32910 Positive_regulation of Gene_expression of Oprl1 3 22 0.70 7.07 19.03
151 INT30312 Binding of Pdyn 3 30 0.37 4.2 18.23
152 INT9179 Positive_regulation of Localization of Ghrh 4 42 0.70 7.05 18.1
153 INT9780 Regulation of Penk 2 30 0.60 6.78 17.19
154 INT35998 Positive_regulation of Gene_expression of Calca 1 31 0.70 16.16 16.98
155 INT7290 Negative_regulation of Transcription of Penk 2 33 0.59 7.28 16.5
156 INT15202 Regulation of Tacr1 1 26 0.60 9.65 16.48
157 INT48238 Regulation of Gene_expression of Ngf 1 25 0.62 11.48 16.42
158 INT8530 Transcription of Penk 1 48 0.70 11.67 16.34
159 INT7531 Positive_regulation of Eef1a1 1 29 0.62 8.16 15.41
160 INT4851 Positive_regulation of Chat 2 53 0.70 9.21 15.11
161 INT60044 Gene_expression of Syn1 1 38 0.78 4.98 14.61
162 INT4736 Gene_expression of Chat 6 67 0.77 17.15 14.24
163 INT60046 Positive_regulation of Syn1 2 16 0.70 2 13.9
164 INT11996 Gene_expression of Ina 2 34 0.67 4.8 13.82
165 INT105156 Phosphorylation of Gfap 5 23 0.79 11.85 13.76
166 INT22003 Negative_regulation of Cpe 1 25 0.58 6.23 12.94
167 INT18372 Positive_regulation of Transcription of Pdyn 2 30 0.69 2.48 12.83
168 INT31368 Positive_regulation of Positive_regulation of Th 1 19 0.51 2.2 12.68
169 INT75421 Regulation of Binding of Ptprg 4 13 0.44 0.96 12.64
170 INT90909 Negative_regulation of Gene_expression of NOS1 1 44 0.55 23.83 12.47
171 INT18539 Gene_expression of Pnmt 1 33 0.78 3.08 12.47
172 INT79405 Gene_expression of Pde4a 6 30 0.78 8.48 12.3
173 INT16659 Gene_expression of Eef1a1 10 34 0.64 6.1 11.85
174 INT57187 Positive_regulation of Gfap 1 49 0.69 27.59 11.46
175 INT79400 Positive_regulation of Pde4a 1 12 0.70 3.78 11.26
176 INT4723 Transcription of Tac1 2 26 0.71 8.33 11.18
177 INT19575 Negative_regulation of Positive_regulation of Abat 2 14 0.43 2.07 11.05
178 INT11205 Gene_expression of Prep 11 65 0.77 8.11 10.12
179 INT48496 Regulation of Transcription of Th 2 16 0.54 2.29 10.02
180 INT1617 Positive_regulation of Binding of Oprl1 1 10 0.59 0.63 9.79
181 INT32239 Gene_expression of Car3 1 38 0.67 6.86 9.76
182 INT53983 Gene_expression of Opcml 7 30 0.78 10.35 9.69
183 INT336 Negative_regulation of Gad1 1 19 0.58 7.71 9.51
184 INT26248 Positive_regulation of Ptprg 2 12 0.40 1.42 9.48
185 INT13610 Regulation of Acyp2-ps1 1 10 0.62 3.29 9.4
186 INT48978 Negative_regulation of FOS 4 41 0.57 11.94 9.14
187 INT13296 Transcription of Drd2 2 17 0.66 2.7 9.07
188 INT9387 Positive_regulation of Cpe 1 27 0.70 3.99 8.87
189 INT15308 Localization of Chat 1 29 0.81 2.35 8.47
190 INT16735 Localization of Drd1a 1 11 0.61 0.35 8.42
191 INT3983 Positive_regulation of Acot1 2 30 0.68 5.83 8.34
192 INT6557 Gene_expression of Eno2 4 65 0.77 54.42 8.17
193 INT6384 Regulation of Eef1a1 2 21 0.61 2.95 7.97
194 INT28358 Gene_expression of Nanog 2 25 0.70 3.52 7.85
195 INT51206 Regulation of Gene_expression of Tac1 1 13 0.45 5.92 7.74
196 INT1664 Gene_expression of Kitl 1 30 0.65 13.63 7.47
197 INT78432 Negative_regulation of Gene_expression of Oprl1 2 6 0.58 3.27 7.24
198 INT6576 Localization of Adra2a 1 11 0.71 1.49 7.18
199 INT98310 Regulation of gr 1 21 0.39 15.04 6.68
200 INT3506 Localization of TH 2 12 0.81 0.78 6.66
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