J:CNS Drug Rev

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT127738 Binding of Crygb and Pnoc 2 1 0.49 0.1 0.99
2 INT132580 Binding of ADRA2C and Htr1a 1 1 0.41 0.27 0.45
3 INT132585 GABBR1 Positive_regulation of Binding of Gabbr1 1 1 0.01 0.6 0.3
4 INT128541 Pnoc Positive_regulation of Crygb 1 1 0.21 0 0.29

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT728 Positive_regulation of Penk 1 1068 0.70 186.9 636.87
2 INT50058 Negative_regulation of Cpox 2 907 0.58 426.28 428.29
3 INT1395 Negative_regulation of Penk 1 537 0.59 87.33 389.81
4 INT1212 Binding of Oprl1 1 312 0.48 28.6 225.15
5 INT626 Localization of CALCA 2 289 0.81 125.39 221.15
6 INT51921 Gene_expression of Cpox 1 501 0.73 229.81 157.81
7 INT6042 Binding of Oprm1 1 248 0.48 31.77 154.34
8 INT1614 Gene_expression of Oprl1 1 164 0.78 31.43 127.74
9 INT1438 Localization of Pomc 2 360 0.81 101.26 116.47
10 INT8413 Gene_expression of Ptgs1 1 248 0.78 110.17 108.58
11 INT293 Protein_catabolism of Penk 2 161 1.00 11.71 98.45
12 INT73340 Negative_regulation of Faah 3 134 0.59 38.67 85.03
13 INT20964 Gene_expression of OPRK1 1 96 0.78 23.54 58.18
14 INT7093 Negative_regulation of CYP2B6 1 146 0.58 37.3 48.39
15 INT789 Positive_regulation of YY1 1 69 0.67 14.07 47.06
16 INT15347 Positive_regulation of Localization of Pomc 1 81 0.70 28.1 31.01
17 INT10684 Negative_regulation of Protein_catabolism of Penk 2 41 0.59 2.33 28.63
18 INT39914 Negative_regulation of Cyp1a2 1 44 0.58 10.04 22
19 INT40811 Binding of OPRL1 1 26 0.48 2.76 18.68
20 INT73338 Gene_expression of Faah 1 21 0.77 6.72 10.73
21 INT6356 Binding of Gabbr1 2 30 0.48 4.62 9.82
22 INT3703 Negative_regulation of Grhpr 1 38 0.50 11.43 9.2
23 INT65661 Positive_regulation of Ado 1 13 0.52 4.75 8.54
24 INT35307 Regulation of Adk 1 11 0.35 3.21 7.79
25 INT122080 Positive_regulation of Crygb 1 10 0.45 4.32 7.14
26 INT2039 Regulation of CYP2B6 1 30 0.60 7.75 6.43
27 INT58700 Binding of Slc16a11 1 11 0.42 1.17 6.38
28 INT55309 Positive_regulation of Ssr1 1 20 0.46 5.97 5.74
29 INT63781 Regulation of Ado 1 8 0.34 3.78 5.19
30 INT81226 Gene_expression of Adk 1 9 0.64 9.28 4.81
31 INT33035 Positive_regulation of Stmn1 2 5 0.30 0.56 4.24
32 INT143623 Binding of Dpysl2 2 7 0.48 3.18 3.93
33 INT54495 Binding of GABBR1 1 9 0.35 1.82 2.76
34 INT86625 Binding of Pla2g1b 1 8 0.24 2.52 2.43
35 INT136934 Negative_regulation of Urb1 1 6 0.36 2.53 2.38
36 INT56337 Regulation of Cyp1a2 1 8 0.27 1.09 2.33
37 INT148456 Gene_expression of LY96 1 7 0.19 4.35 2.02
38 INT143624 Binding of Dpysl2 2 3 0.38 0.92 1.76
39 INT136933 Gene_expression of Urb1 1 3 0.51 0.42 1.57
40 INT98160 Binding of Slurp1 1 4 0.41 0.52 0.94
41 INT105540 Binding of FMO1 1 1 0.33 0.47 0.73
42 INT100973 Positive_regulation of Adk 1 1 0.09 0.56 0.64
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