J:Cancer Informatics

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT326126 Binding of S100A1 and TP53 1 1 0.04 1.34 0.09
2 INT268679 Binding of HDAC1 and NCOR2 3 2 0.17 2.8 0.07
3 INT87808 Binding of Gpt and HCC 3 1 0.04 5.09 0.07
4 INT268673 Binding of NCOR2 and BCOR 1 2 0.01 2.54 0.07
5 INT268675 Binding of NCOR2 and SIN3A 1 2 0.27 2.54 0.07
6 INT268678 Binding of HDAC2 and NCOR2 1 2 0.18 2.67 0.07
7 INT326125 Binding of CXCL3 and IL1RAPL1 1 1 0.01 1.16 0.05
8 INT268677 IFNA2 Positive_regulation of XRCC1 1 1 0.05 0.75 0.05
9 INT326128 Binding of CXCL3 and CXCL6 1 1 0.06 1.18 0.05
10 INT326127 Binding of CXCL3 and CXCR1 1 1 0.13 1.16 0.05
11 INT268674 IL2 Positive_regulation of XRCC1 1 1 0.08 0.75 0.05
12 INT268665 Ptger2 Positive_regulation of Gene_expression of Mcl1 1 1 0.03 0.9 0.04
13 INT268676 Binding of HDAC1 and BCOR 1 1 0.01 1.31 0.04
14 INT268664 Ptger2 Positive_regulation of Bcl2 1 1 0.02 0.9 0.04
15 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 1 0.02 0.9 0.04
16 INT326163 Binding of Racgap1 and RAB12 1 1 0.00 0.68 0
17 INT326162 Binding of ABHD2 and Scrib 1 1 0.00 1.07 0
18 INT326165 Binding of ABHD12 and Scrib 1 1 0.00 1.01 0
19 INT326164 Binding of S100A2 and Scrib 1 1 0.01 1.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9659 Gene_expression of Il6 1 991 0.78 715.11 265.57
2 INT68684 Gene_expression of VEGFA 2 2371 0.78 1742.52 259.2
3 INT49441 Negative_regulation of Cpox 3 494 0.59 303.22 177.46
4 INT9852 Positive_regulation of Gpt 3 563 0.70 364.64 146.82
5 INT60694 Gene_expression of Il10 1 567 0.78 369.48 143.69
6 INT49439 Gene_expression of Cpox 6 508 0.73 326.97 130.17
7 INT20374 Gene_expression of Il4 1 515 0.76 306.15 114.12
8 INT940 Negative_regulation of Ptgs1 3 219 0.59 104.34 95.97
9 INT39565 Gene_expression of Ptger2 2 424 0.75 229.28 72.68
10 INT11807 Gene_expression of Il2 1 266 0.78 112 64.97
11 INT9657 Positive_regulation of Gene_expression of Il6 1 237 0.70 180.45 63.6
12 INT17564 Gene_expression of Gpt 14 322 0.75 208.51 60.36
13 INT60695 Positive_regulation of Gene_expression of Il10 1 154 0.70 120.28 43.07
14 INT77307 Gene_expression of Bcl2 1 399 0.77 319.77 38
15 INT67039 Positive_regulation of Cpox 2 144 0.65 98.4 33.77
16 INT54302 Positive_regulation of Gene_expression of Il4 1 126 0.68 86.18 30.75
17 INT11650 Negative_regulation of Gpt 6 122 0.59 69.15 30.36
18 INT47075 Positive_regulation of Ptger2 2 142 0.70 78.55 25.47
19 INT27933 Gene_expression of NCOR2 1 65 0.72 31.35 24.23
20 INT35716 Positive_regulation of NCOR2 1 45 0.60 18 23.54
21 INT69993 Positive_regulation of Gene_expression of Cpox 4 93 0.55 69.4 22.05
22 INT12922 Gene_expression of Atp9a 1 115 0.75 50.95 17.01
23 INT108780 Positive_regulation of Gene_expression of Ptger2 2 94 0.49 59.71 16.22
24 INT17565 Regulation of Gpt 1 85 0.60 43.64 13.68
25 INT22213 Localization of Gpt 2 52 0.78 34.05 12.94
26 INT92574 Gene_expression of CXCL5 1 51 0.78 24.87 11.89
27 INT81640 Positive_regulation of Gene_expression of Bcl2 1 106 0.69 84.58 11.63
28 INT119700 Gene_expression of VDR 2 88 0.75 65.33 11.5
29 INT11649 Negative_regulation of Positive_regulation of Gpt 1 25 0.59 13.94 10.87
30 INT75137 Regulation of Akt1 1 74 0.48 37.89 9.7
31 INT62166 Positive_regulation of Gene_expression of Gpt 3 64 0.50 39.13 9.69
32 INT24328 Gene_expression of Egf 2 97 0.75 59.65 9.42
33 INT60285 Negative_regulation of Racgap1 2 27 0.56 21.71 8.14
34 INT80220 Positive_regulation of Bcl2 1 71 0.58 57.73 7.86
35 INT127691 Gene_expression of CXCL1 1 23 0.66 18.11 7.04
36 INT24907 Gene_expression of PAPPA 1 42 0.75 28.32 6.63
37 INT39516 Gene_expression of Alb 4 81 0.75 30.08 6.59
38 INT52749 Gene_expression of alp 1 24 0.44 12.84 5.97
39 INT112124 Positive_regulation of Egfr 2 71 0.70 47.82 5.61
40 INT85653 Regulation of Gene_expression of Cpox 1 24 0.24 20.55 5.22
41 INT14470 Gene_expression of HCC 4 83 0.67 110.55 4.61
42 INT16349 Positive_regulation of alp 2 25 0.60 16.74 4.34
43 INT147697 Gene_expression of ABHD2 1 8 0.78 8.15 4.3
44 INT15375 Gene_expression of AXL 2 21 0.65 18.5 3.74
45 INT38303 Binding of Gpt 1 21 0.47 15.84 3.43
46 INT121493 Gene_expression of XRCC1 2 55 0.65 73.43 2.76
47 INT145328 Negative_regulation of Scrib 1 25 0.16 26.79 2.66
48 INT119025 Gene_expression of NOTCH1 1 46 0.75 31.32 2.64
49 INT72165 Gene_expression of CXCL6 2 8 0.52 4.76 2.6
50 INT72782 Positive_regulation of HCC 3 41 0.40 63.74 2.46
51 INT213681 Gene_expression of TYMS 4 9 0.33 8.96 2.45
52 INT205081 Positive_regulation of Gene_expression of AXL 1 10 0.58 11.27 2.37
53 INT97973 Positive_regulation of XRCC1 1 24 0.40 30.95 2.26
54 INT17617 Gene_expression of ABL2 1 8 0.75 2.73 2.25
55 INT101641 Gene_expression of Mcl1 1 25 0.54 20.3 2.23
56 INT21487 Negative_regulation of HCC 7 18 0.49 29.81 1.88
57 INT243184 Positive_regulation of Gene_expression of CXCL5 1 11 0.61 5.1 1.88
58 INT56925 Negative_regulation of TSC1 2 54 0.52 63.39 1.87
59 INT44723 Positive_regulation of ABL2 1 7 0.49 2.23 1.82
60 INT20992 Regulation of ITGB2 1 11 0.37 9.04 1.73
61 INT127692 Positive_regulation of Gene_expression of CXCL1 1 8 0.56 6.26 1.71
62 INT127145 Gene_expression of SET 5 46 0.65 10.39 1.7
63 INT43637 Positive_regulation of AXL 1 11 0.58 11.71 1.59
64 INT82866 Localization of Atp9a 1 13 0.78 6.95 1.56
65 INT58884 Gene_expression of SLC25A5 3 4 0.75 4.53 1.43
66 INT213442 Gene_expression of CXCL3 2 8 0.57 6.3 1.41
67 INT108325 Gene_expression of Scrib 1 26 0.39 48.33 1.39
68 INT208592 Binding of CXCR1 1 3 0.36 2.26 1.32
69 INT70615 Binding of TXNRD1 1 25 0.36 12.15 1.27
70 INT81400 Binding of RARA 1 25 0.36 12.93 1.27
71 INT209962 Binding of RDBP 1 4 0.11 2.93 1.27
72 INT74018 Binding of XRCC1 4 19 0.31 24.78 1.24
73 INT157765 Negative_regulation of CDH1 1 32 0.53 35.72 1.15
74 INT58650 Positive_regulation of NOL3 1 5 0.67 1.75 1.15
75 INT268662 Regulation of Araf 1 4 0.17 2.5 1.13
76 INT74020 Negative_regulation of XRCC1 2 16 0.35 17.18 1.06
77 INT190031 Binding of Scrib 4 19 0.36 21.9 1.01
78 INT72162 Positive_regulation of Gene_expression of CXCL6 1 2 0.25 1.15 0.96
79 INT74021 Regulation of XRCC1 8 15 0.44 16.91 0.88
80 INT181129 Positive_regulation of Araf 1 8 0.21 4.3 0.79
81 INT36200 Gene_expression of S100A1 1 9 0.77 9.56 0.75
82 INT83743 Gene_expression of SULT1B1 1 7 0.76 0.93 0.71
83 INT228279 Regulation of Gene_expression of Egf 1 7 0.43 6.64 0.65
84 INT80300 Gene_expression of TFAP2A 1 5 0.54 2.76 0.59
85 INT127975 Negative_regulation of SPP1 1 15 0.42 11.25 0.56
86 INT158327 Negative_regulation of Mcl1 1 5 0.42 4.08 0.55
87 INT158329 Positive_regulation of Gene_expression of Mcl1 1 9 0.32 7.53 0.54
88 INT56598 Transcription of Gpt 1 4 0.34 1.65 0.5
89 INT19581 Regulation of NPHS1 1 3 0.25 2.38 0.5
90 INT158426 Binding of NOTCH1 1 10 0.36 7.95 0.45
91 INT87456 Regulation of CD81 1 1 0.17 1.71 0.43
92 INT87457 Negative_regulation of CD81 1 3 0.37 1.73 0.42
93 INT173095 Positive_regulation of Gene_expression of NCOR2 1 3 0.39 2.83 0.39
94 INT245297 Localization of CXCL6 1 2 0.37 1.29 0.38
95 INT194779 Binding of VAV1 2 2 0.14 1.62 0.36
96 INT326147 Negative_regulation of UGT2B28 3 1 0.25 1.51 0.35
97 INT240601 Positive_regulation of Gene_expression of CXCL3 1 3 0.43 2.84 0.34
98 INT173635 Negative_regulation of TFAP2A 1 3 0.34 2.93 0.33
99 INT274704 Localization of GPT 1 5 0.73 3.91 0.29
100 INT326154 Regulation of ETS1 2 1 0.07 1.69 0.29
101 INT248401 Gene_expression of CDKN1C 1 21 0.67 14.52 0.23
102 INT231829 Negative_regulation of ARHGDIA 1 2 0.09 1.01 0.21
103 INT188319 Regulation of Negative_regulation of Gpt 1 2 0.09 1.91 0.21
104 INT326144 Binding of IL1RAPL1 1 1 0.02 0.59 0.2
105 INT206433 Negative_regulation of SULT1B1 1 3 0.48 1.25 0.18
106 INT219486 Positive_regulation of OIT3 2 2 0.20 1.37 0.15
107 INT326155 Localization of UGT2B28 1 1 0.31 0.62 0.15
108 INT316515 Positive_regulation of RALBP1 1 28 0.25 10.37 0.14
109 INT326152 Gene_expression of S100A2 1 1 0.24 1.32 0.13
110 INT326145 Gene_expression of ABHD12 1 1 0.16 1.33 0.12
111 INT326158 Gene_expression of OIT3 1 1 0.28 1.34 0.12
112 INT316511 Gene_expression of RALBP1 3 5 0.28 5.24 0.1
113 INT268706 Phosphorylation of ADH6 1 1 0.34 1.03 0.09
114 INT326161 Localization of S100A2 1 1 0.27 1.3 0.09
115 INT268695 Phosphorylation of ATP6V1B1 1 1 0.58 0.96 0.09
116 INT268708 Phosphorylation of APOC1 1 1 0.38 1.02 0.09
117 INT268701 Negative_regulation of SLC25A5 1 2 0.31 2.61 0.08
118 INT23436 Gene_expression of ODZ1 1 3 0.65 2.55 0.07
119 INT268683 Positive_regulation of JAZF1 1 2 0.34 2.85 0.07
120 INT326140 Transcription of SULT1B1 1 1 0.17 0.87 0.06
121 INT310119 Regulation of Gene_expression of SET 2 5 0.32 0.49 0.05
122 INT268705 Phosphorylation of SLC25A5 1 1 0.46 1.22 0.05
123 INT268689 Negative_regulation of Gene_expression of SLC25A5 1 1 0.31 1.16 0.05
124 INT268685 Negative_regulation of Phosphorylation of SLC25A5 1 1 0.31 1.28 0.05
125 INT326153 Gene_expression of CNA1 6 7 0.01 5.52 0.04
126 INT288232 Binding of TYMS 1 2 0.11 2.77 0.04
127 INT326141 Localization of SULT1B1 1 1 0.24 0.63 0.04
128 INT326160 Gene_expression of RAB12 1 1 0.20 1.38 0.04
129 INT326149 Negative_regulation of Negative_regulation of UGT2B28 1 1 0.18 1.14 0.04
130 INT326156 Gene_expression of RNMT 1 1 0.16 1.38 0.04
131 INT237127 Binding of alp 1 3 0.28 0.51 0.03
132 INT268694 Regulation of Gene_expression of NCOR2 1 2 0.42 1.27 0.03
133 INT326159 Positive_regulation of Gene_expression of RALBP1 1 1 0.25 1.58 0.03
134 INT268660 Positive_regulation of Traf5 1 1 0.32 0.83 0.03
135 INT268681 Binding of GTF2B 1 1 0.21 1.16 0.03
136 INT226288 Negative_regulation of SFRP1 1 6 0.43 4.45 0
137 INT300524 Regulation of SET 1 4 0.28 1.19 0
138 INT248399 Negative_regulation of CDKN1C 1 2 0.37 2.71 0
139 INT268704 Positive_regulation of ARC 1 2 0.38 2.42 0
140 INT268686 Gene_expression of JAZF1 1 2 0.68 9.33 0
141 INT268691 Gene_expression of TUBB 1 2 0.38 1.26 0
142 INT268707 Regulation of WASF2 1 2 0.31 1.28 0
143 INT326142 Positive_regulation of Gene_expression of TYMS 2 1 0.16 2.47 0
144 INT326137 Protein_catabolism of Ctnnb1 1 1 0.02 1.08 0
145 INT268709 Positive_regulation of Gene_expression of TUBB 1 1 0.34 1.19 0
146 INT326151 Binding of CNA1 1 1 0.00 0.25 0
147 INT326146 Binding of ABHD6 1 1 0.10 1 0
148 INT268693 Positive_regulation of INHBB 1 1 0.26 1.62 0
149 INT326143 Localization of ABHD12 1 1 0.18 0.95 0
150 INT326139 Binding of C9orf86 1 1 0.02 1 0
151 INT268682 Gene_expression of RASD1 1 1 0.48 0.84 0
152 INT326150 Localization of RAB12 1 1 0.23 1.15 0
153 INT268690 Negative_regulation of PTPRO 1 1 0.26 1.68 0
154 INT326136 Binding of Snai1 1 1 0.04 1.23 0
155 INT268687 Regulation of CLDN1 1 1 0.14 1.18 0
156 INT268703 Gene_expression of WASF2 1 1 0.49 0.77 0
157 INT268698 Regulation of ITPR2 1 1 0.18 1.18 0
158 INT268702 Negative_regulation of MT1G 1 1 0.27 1.69 0
159 INT268700 Gene_expression of PTPRO 1 1 0.41 0.83 0
160 INT268692 Negative_regulation of AIM1 1 1 0.26 1.68 0
161 INT268697 Positive_regulation of TCHP 1 1 0.07 1.86 0
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