J:Cell Commun Signal

From wiki-pain
Jump to: navigation, search

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT185937 NOS2 Regulation of Prkaca 1 1 0.03 1.08 0.82
2 INT178437 Mapk8 Positive_regulation of Jun 3 1 0.40 2.69 0.58
3 INT185917 Binding of AR and MAPK1 1 1 0.07 0.5 0.47
4 INT178446 Binding of Egfr and ras 1 1 0.04 0.13 0.13
5 INT178431 Positive_regulation of Binding of Egfr and ras 1 1 0.05 0.13 0.13
6 INT185918 AR Positive_regulation of Gene_expression of NOS2 1 1 0.12 0.21 0.11
7 INT184814 NOS3 Positive_regulation of Gene_expression of NOS1 1 1 0.09 0.54 0.1
8 INT178434 Il6 Positive_regulation of Ar 1 2 0.01 0.93 0.08
9 INT178438 Mapk8 Positive_regulation of Plau 1 1 0.06 0.52 0.06
10 INT178430 Pawr Positive_regulation of Phosphorylation of Mapk14 1 1 0.05 0.29 0.05
11 INT319764 Large Positive_regulation of Transcription of Cnr1 1 1 0.19 0.21 0.05
12 INT178447 Negative_regulation of Pawr Positive_regulation of Phosphorylation of Mapk14 1 1 0.05 0.29 0.05
13 INT178443 Negative_regulation of Mapk8 Positive_regulation of Negative_regulation of Mapk14 1 1 0.13 0.76 0.04
14 INT178441 Binding of Ar and Sra1 1 1 0.00 0.45 0.04
15 INT178435 Mapk1 Regulation of Phosphorylation of Src 1 1 0.03 0.49 0.04
16 INT178436 Mapk14 Positive_regulation of Gene_expression of Hist1h1a 1 1 0.17 0.2 0.04
17 INT178439 Binding of Ar and Src 1 1 0.01 0.44 0.04
18 INT185938 Phosphorylation of Prkaca Positive_regulation of CREB1 1 1 0.04 0.07 0.04
19 INT178428 Regulation of Il6 Positive_regulation of Ar 1 1 0.01 0.47 0.04
20 INT319763 Large Positive_regulation of Transcription of Nes 1 1 0.14 0.2 0.03
21 INT319765 Large Positive_regulation of Gopc 1 1 0.08 0.15 0.03
22 INT319766 Large Positive_regulation of Nes 1 1 0.20 0.15 0.03
23 INT178442 Mapk1 Regulation of Gene_expression of Il6 1 1 0.03 0.59 0.03
24 INT178440 Map2k4 Positive_regulation of Mapk14 1 1 0.04 0.13 0
25 INT178448 Mapk1 Regulation of Localization of VEGFA 1 1 0.01 0.51 0
26 INT178433 Fgf1 Positive_regulation of Mapk14 1 1 0.02 0.65 0
27 INT178445 Map2k4 Positive_regulation of Mapk8 1 1 0.11 0.13 0
28 INT178432 Map2k7 Positive_regulation of Mapk8 1 1 0.11 0.13 0
29 INT178429 Negative_regulation of Mapk1 Negative_regulation of Positive_regulation of Eno2 1 1 0.02 0.73 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9659 Gene_expression of Il6 2 991 0.78 715.11 265.57
2 INT95787 Positive_regulation of Mapk1 23 568 0.70 226.51 220.94
3 INT49441 Negative_regulation of Cpox 1 494 0.59 303.22 177.46
4 INT120811 Gene_expression of Gopc 3 1174 0.59 428.49 150.55
5 INT49439 Gene_expression of Cpox 1 508 0.73 326.97 130.17
6 INT64161 Positive_regulation of Prkca 1 213 0.70 85.06 129.91
7 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1 1138 0.72 311.58 119.18
8 INT62124 Gene_expression of NOS1 6 444 0.78 218.08 114.85
9 INT48593 Positive_regulation of NOS1 1 420 0.68 226.15 114.71
10 INT65731 Gene_expression of Cnr1 16 234 0.78 63.82 109.34
11 INT27096 Positive_regulation of Nfkb1 2 325 0.70 195.11 109.06
12 INT71789 Positive_regulation of MAPK1 1 396 0.70 234.44 89.27
13 INT96917 Positive_regulation of Mapk14 9 261 0.70 173.29 88.79
14 INT15898 Positive_regulation of Prkaca 6 199 0.70 50.89 87.54
15 INT92434 Phosphorylation of Mapk1 3 287 0.82 91.65 83.46
16 INT53964 Negative_regulation of Prkaca 2 131 0.58 38.76 69.52
17 INT65733 Positive_regulation of Cnr1 6 125 0.70 40.27 67.33
18 INT64159 Gene_expression of Prkca 1 90 0.78 34.65 55.97
19 INT96914 Phosphorylation of Mapk14 1 168 0.82 108.46 53.32
20 INT50334 Negative_regulation of Cnr1 5 84 0.58 30.86 51.75
21 INT71786 Phosphorylation of MAPK1 11 256 0.82 110.09 46.17
22 INT110023 Negative_regulation of Mapk14 3 127 0.59 84.27 45.42
23 INT63383 Binding of Cnr1 1 77 0.48 22.28 44.61
24 INT66383 Phosphorylation of Prkaca 4 143 0.80 30.85 43.38
25 INT114751 Gene_expression of Mapk1 5 137 0.76 60.14 39.98
26 INT102611 Negative_regulation of Positive_regulation of Mapk1 1 74 0.58 35.57 39.37
27 INT101992 Localization of VEGFA 1 413 0.81 258.23 36.15
28 INT59466 Gene_expression of ISYNA1 1 204 0.77 112.57 35.48
29 INT79060 Gene_expression of NOS2 14 116 0.78 69.25 34.84
30 INT66005 Regulation of Cnr1 4 47 0.61 19.21 34.52
31 INT96913 Positive_regulation of Mapk8 25 179 0.69 130.44 32.2
32 INT117112 Negative_regulation of Mapk1 4 87 0.56 40.34 31.18
33 INT110020 Gene_expression of Mapk14 2 142 0.77 72.33 30.08
34 INT6660 Positive_regulation of Jun 1 148 0.69 67.58 29.73
35 INT64113 Positive_regulation of Gene_expression of NOS1 2 110 0.60 71.03 29.72
36 INT28361 Gene_expression of TP53 1 443 0.78 384.86 28.8
37 INT66381 Regulation of Prkaca 1 40 0.62 13.38 27.96
38 INT22045 Gene_expression of IRF6 1 158 0.75 58.07 27.81
39 INT5206 Gene_expression of AR 5 316 0.78 113.83 27.29
40 INT16428 Positive_regulation of Gtf3a 1 135 0.20 106.44 26.67
41 INT76095 Positive_regulation of ISYNA1 2 117 0.55 79.73 25.86
42 INT95788 Positive_regulation of Positive_regulation of Mapk1 1 83 0.69 24.75 25.84
43 INT11014 Phosphorylation of CREB1 9 72 0.81 26.35 25.64
44 INT12124 Gene_expression of MAPK1 2 141 0.75 82.4 25.58
45 INT48766 Regulation of NOS1 1 73 0.61 37.01 24.59
46 INT79061 Positive_regulation of NOS2 6 92 0.65 58.89 23.96
47 INT71781 Phosphorylation of MAPK3 1 62 0.80 27.73 23.73
48 INT70504 Regulation of Gene_expression of NOS1 2 30 0.51 21.72 21.72
49 INT1561 Negative_regulation of Dnahc8 1 59 0.59 18.12 20.99
50 INT85952 Positive_regulation of AR 15 168 0.67 64.36 20.66
51 INT91462 Positive_regulation of Phosphorylation of MAPK1 7 99 0.67 40.28 18.99
52 INT9656 Regulation of Gene_expression of Il6 1 57 0.62 33.3 17.71
53 INT111531 Negative_regulation of Phosphorylation of Mapk14 1 37 0.50 20 17.68
54 INT109316 Negative_regulation of Mapk8 4 72 0.59 50.59 17.24
55 INT87932 Positive_regulation of Gene_expression of Cnr1 3 28 0.69 8.86 16.38
56 INT95790 Regulation of Mapk1 3 55 0.61 21.17 16.31
57 INT98647 Positive_regulation of Mdk 1 65 0.59 32.93 15.67
58 INT96911 Positive_regulation of Phosphorylation of Mapk14 1 46 0.70 43.03 15.15
59 INT77619 Gene_expression of Prkaca 1 43 0.75 8.55 14.13
60 INT83201 Gene_expression of NOS3 1 93 0.78 47.16 12.48
61 INT119396 Regulation of Positive_regulation of Mapk1 1 22 0.61 7.88 12.25
62 INT117113 Regulation of Mapk14 1 28 0.45 16.71 11.99
63 INT109315 Gene_expression of Mapk8 10 70 0.78 45.46 11.65
64 INT96915 Phosphorylation of Mapk8 5 73 0.81 40.69 11.44
65 INT95369 Positive_regulation of Gene_expression of NOS2 4 36 0.55 25.09 11.37
66 INT121796 Gene_expression of NeuN 3 92 0.78 23.18 10.53
67 INT87451 Positive_regulation of Mapk3 2 34 0.67 12.82 10.38
68 INT790 Gene_expression of Mastl 2 22 0.68 4.56 10.23
69 INT145695 Regulation of Mapk8 2 26 0.62 14.67 9.83
70 INT66382 Positive_regulation of Phosphorylation of Prkaca 1 33 0.49 7.05 9.69
71 INT24328 Gene_expression of Egf 1 97 0.75 59.65 9.42
72 INT101105 Positive_regulation of FUT1 3 62 0.30 55.96 9.28
73 INT54588 Positive_regulation of CREB1 2 38 0.67 12.01 9.18
74 INT94196 Negative_regulation of Phosphorylation of MAPK1 3 60 0.59 31.64 9.16
75 INT35366 Binding of AR 1 87 0.47 30.52 8.9
76 INT71478 Positive_regulation of Positive_regulation of Prkaca 2 21 0.37 5.14 8.85
77 INT71785 Gene_expression of MAPK3 1 22 0.75 11.35 8.21
78 INT96912 Positive_regulation of Phosphorylation of Mapk8 3 29 0.69 18.33 8.14
79 INT87271 Positive_regulation of Phosphorylation of CREB1 4 27 0.66 12.87 7.91
80 INT65246 Negative_regulation of Nos3 1 36 0.50 25.65 7.62
81 INT113705 Gene_expression of Egfr 1 228 0.78 149.05 7.59
82 INT13348 Negative_regulation of Mastl 1 11 0.36 3.33 7.28
83 INT64370 Gene_expression of Neurod1 1 22 0.75 5.19 7.1
84 INT73709 Binding of Mastl 2 11 0.40 3.39 6.76
85 INT89131 Negative_regulation of NOS2 2 20 0.58 9.68 6.56
86 INT61258 Transcription of Nfkb1 1 24 0.67 10.89 6.32
87 INT48911 Binding of NOS1 1 24 0.40 11.21 5.89
88 INT6667 Gene_expression of CREB1 1 27 0.77 6.29 5.84
89 INT85404 Transcription of Cnr1 3 12 0.72 3.15 5.73
90 INT94428 Negative_regulation of Gene_expression of NOS2 1 20 0.47 11.61 5.62
91 INT112124 Positive_regulation of Egfr 2 71 0.70 47.82 5.61
92 INT71477 Negative_regulation of Positive_regulation of Prkaca 1 10 0.37 1.69 5.57
93 INT111100 Gene_expression of Dusp1 2 18 0.76 14.81 5.21
94 INT34770 Negative_regulation of PTGIR 1 16 0.41 8.52 5.21
95 INT135291 Positive_regulation of Positive_regulation of Mapk8 3 24 0.64 19.37 5.16
96 INT131717 Positive_regulation of Gene_expression of Mapk8 5 18 0.55 14.25 5.02
97 INT83680 Gene_expression of FUT1 1 40 0.26 25.45 4.98
98 INT105923 Binding of FUT1 4 34 0.14 17.81 4.79
99 INT106524 Phosphorylation of Jun 1 23 0.80 15.35 4.78
100 INT141000 Negative_regulation of GSK 1 24 0.57 9.46 4.4
101 INT108354 Negative_regulation of Phosphorylation of Prkaca 1 18 0.41 6.24 4.37
102 INT94427 Positive_regulation of Positive_regulation of NOS2 1 14 0.47 11.15 4.3
103 INT75523 Regulation of MAPK8 1 21 0.33 11.18 4.28
104 INT158416 Localization of Mapk1 1 19 0.67 5.32 4.18
105 INT26584 Gene_expression of Nes 5 76 0.75 24.03 4.17
106 INT23653 Binding of Egf 4 22 0.36 11.34 4.12
107 INT90983 Regulation of Gene_expression of Cnr1 1 8 0.45 2.59 4.03
108 INT31758 Positive_regulation of Egf 1 32 0.66 19.42 3.64
109 INT5204 Positive_regulation of Gene_expression of AR 1 60 0.67 23.54 3.53
110 INT102573 Protein_catabolism of Faah 1 8 0.80 2.89 3.52
111 INT137350 Phosphorylation of Src 1 13 0.45 4.14 3.32
112 INT137609 Localization of Vegfa 1 22 0.78 14.67 3.01
113 INT110755 Negative_regulation of Positive_regulation of Mapk8 3 15 0.46 9.91 2.98
114 INT98686 Gene_expression of Calb2 2 28 0.51 12.07 2.84
115 INT98919 Negative_regulation of Phosphorylation of CREB1 1 8 0.58 2.4 2.63
116 INT15695 Positive_regulation of EIF2AK3 4 12 0.67 7.01 2.56
117 INT185927 Positive_regulation of Positive_regulation of AR 2 12 0.34 6.35 2.5
118 INT76094 Localization of NOS2 1 8 0.72 2.76 2.34
119 INT192980 Negative_regulation of NeuN 1 14 0.36 5.24 2.32
120 INT83799 Phosphorylation of Bcl2l1 1 8 0.82 7.86 2.23
121 INT94060 Transcription of ISYNA1 1 18 0.43 6.7 2.18
122 INT127756 Negative_regulation of Map2k1 1 10 0.41 6.69 2.04
123 INT109906 Localization of MAPK1 1 12 0.54 1.68 2.01
124 INT169874 Positive_regulation of Gene_expression of Prkaca 2 11 0.38 1.64 2.01
125 INT96916 Negative_regulation of Phosphorylation of Mapk8 1 16 0.52 9.68 1.97
126 INT178389 Positive_regulation of Eno2 1 3 0.06 1.01 1.76
127 INT58210 Gene_expression of Pcsk1 1 11 0.70 5.63 1.71
128 INT79063 Regulation of Gene_expression of NOS2 1 6 0.43 3.68 1.7
129 INT206477 Gene_expression of Prox1 1 7 0.56 4.34 1.65
130 INT149994 Gene_expression of Mapk3 1 16 0.65 3.45 1.62
131 INT223916 Gene_expression of Dgkb 1 2 0.58 1.22 1.55
132 INT130019 Regulation of Phosphorylation of MAPK1 1 6 0.49 3.6 1.5
133 INT115463 Positive_regulation of Plau 1 13 0.47 8.47 1.49
134 INT147788 Regulation of FUT1 1 11 0.12 7.72 1.44
135 INT121307 Gene_expression of Ercc1 1 4 0.73 12.69 1.37
136 INT213894 Positive_regulation of Transcription of Cnr1 1 3 0.69 0.81 1.34
137 INT85765 Localization of PEBP1 1 3 0.73 0.83 1.3
138 INT127900 Phosphorylation of EIF2AK3 2 14 0.80 7.99 1.22
139 INT138287 Gene_expression of Map2k1 1 69 0.65 46.14 1.02
140 INT215148 Gene_expression of Dcx 6 13 0.75 6.57 1.02
141 INT185929 Regulation of Gene_expression of IRF6 1 9 0.20 1.66 0.99
142 INT178391 Localization of Mapk14 1 9 0.68 5.27 0.97
143 INT114704 Positive_regulation of Fgf1 1 13 0.50 8.89 0.89
144 INT94059 Positive_regulation of Transcription of ISYNA1 1 5 0.26 3.82 0.85
145 INT127899 Gene_expression of EIF2AK3 1 8 0.75 2.89 0.8
146 INT131286 Binding of Egfr 2 26 0.44 13.58 0.78
147 INT113063 Phosphorylation of Cdk20 1 2 0.80 0.17 0.78
148 INT165105 Localization of Mapk8 1 7 0.69 4.45 0.76
149 INT147790 Positive_regulation of Gene_expression of FUT1 1 9 0.11 4.8 0.54
150 INT19083 Positive_regulation of NRG1 1 3 0.20 0.65 0.48
151 INT116134 Positive_regulation of Positive_regulation of CREB1 1 2 0.28 0.59 0.45
152 INT206482 Positive_regulation of Nes 1 5 0.46 1.6 0.44
153 INT90762 Regulation of Gene_expression of Pcsk1 1 2 0.22 0.58 0.44
154 INT210405 Negative_regulation of Binding of FUT1 2 5 0.14 1.97 0.38
155 INT149995 Negative_regulation of Mapk3 1 5 0.52 2.64 0.32
156 INT178400 Negative_regulation of Gene_expression of Dusp1 2 4 0.40 3.61 0.31
157 INT185926 Regulation of Positive_regulation of Prkaca 1 5 0.26 0.27 0.25
158 INT185930 Regulation of Positive_regulation of AR 1 3 0.20 1.01 0.25
159 INT171374 Binding of Src 1 2 0.13 0.44 0.24
160 INT178399 Regulation of Positive_regulation of Mapk8 1 4 0.44 3.4 0.23
161 INT121311 Positive_regulation of Gene_expression of Ercc1 1 3 0.62 1.23 0.21
162 INT178414 Phosphorylation of Ifi44 1 2 0.79 0.17 0.21
163 INT178411 Regulation of Negative_regulation of Mapk1 1 1 0.44 0.94 0.19
164 INT171378 Negative_regulation of Binding of Egfr 1 3 0.43 1.48 0.16
165 INT175527 Localization of Map2k1 1 4 0.31 2.41 0.13
166 INT182289 Phosphorylation of NOS2 3 3 0.46 0.61 0.13
167 INT178420 Positive_regulation of PEBP1 2 3 0.42 1.77 0.12
168 INT171219 Regulation of Plau 1 9 0.42 1.04 0.11
169 INT162432 Positive_regulation of Ar 1 3 0.23 2.34 0.11
170 INT319758 Localization of Dcx 1 2 0.73 0.87 0.1
171 INT185934 Phosphorylation of Calm-ps1 2 1 0.79 0.17 0.09
172 INT178387 Gene_expression of Hist1h1a 2 3 0.65 1.78 0.08
173 INT178393 Positive_regulation of Hist1h1a 1 2 0.67 0.62 0.08
174 INT178419 Regulation of Mapk9 1 1 0.09 0.76 0.08
175 INT178395 Transcription of Mapk14 1 6 0.61 0.47 0.07
176 INT250141 Localization of Nes 1 4 0.43 1.08 0.07
177 INT229149 Positive_regulation of Gene_expression of NeuN 1 4 0.34 0.98 0.07
178 INT273646 Positive_regulation of Binding of FUT1 2 2 0.10 1.51 0.07
179 INT185928 Regulation of Phosphorylation of NOS2 1 1 0.26 0.09 0.07
180 INT185933 Regulation of Phosphorylation of Calm-ps1 1 1 0.44 0.09 0.07
181 INT178410 Negative_regulation of Pawr 1 1 0.12 0.29 0.05
182 INT178412 Negative_regulation of Atp2a3 1 1 0.02 0.68 0.05
183 INT185931 Positive_regulation of Phosphorylation of NOS2 1 1 0.28 0.09 0.05
184 INT185932 Positive_regulation of Phosphorylation of Calm-ps1 1 1 0.49 0.09 0.05
185 INT178418 Binding of Fgf7 2 1 0.16 1.26 0.05
186 INT178408 Positive_regulation of Localization of Mapk14 1 2 0.42 0.87 0.04
187 INT178406 Binding of Sra1 1 2 0.04 0.49 0.04
188 INT178397 Phosphorylation of Sra1 1 1 0.05 0.43 0.04
189 INT178388 Positive_regulation of Localization of Mapk8 1 1 0.40 0.75 0.04
190 INT324140 Positive_regulation of Negative_regulation of GSK 1 1 0.49 0.52 0.04
191 INT206483 Transcription of Nes 1 4 0.52 0.58 0.03
192 INT178396 Positive_regulation of Fgf7 1 2 0.55 0.98 0.03
193 INT178415 Positive_regulation of Stk25 1 1 0.01 0.76 0.03
194 INT121304 Gene_expression of Xrcc1 1 4 0.77 2.95 0
195 INT121308 Positive_regulation of Gene_expression of Xrcc1 1 3 0.50 0.6 0
196 INT178407 Negative_regulation of Positive_regulation of Eno2 1 1 0.04 0.73 0
197 INT178386 Positive_regulation of Ptpra 2 1 0.13 1.14 0
198 INT178413 Binding of Cby1 1 1 0.01 0.51 0
199 INT178394 Positive_regulation of Positive_regulation of Ptpra 1 1 0.13 0.57 0
200 INT178404 Regulation of Negative_regulation of Mapk3 1 1 0.12 0.55 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox