J:Chem. Biol. Interact.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT155096 Stat3 Regulation of Mapk3 1 1 0.36 0.45 0.76
2 INT156087 Binding of AKR1C3 and Akr1c1 1 1 0.05 0.31 0.3
3 INT156083 Binding of AKR1C2 and AKR1C3 1 1 0.05 0.31 0.3
4 INT156084 Binding of PTGS2 and AKR1C3 1 1 0.02 0.31 0.3
5 INT156082 Binding of PTGS1 and AKR1C3 1 1 0.01 0.31 0.3
6 INT156057 UMOD Regulation of GABRG3 1 1 0.01 0.54 0.14
7 INT156056 AKR1C1 Negative_regulation of UMOD 1 1 0.03 0.41 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT18357 Gene_expression of TRPV1 2 825 0.78 307.11 382.81
2 INT34869 Negative_regulation of PTGS2 3 778 0.59 366.76 319.85
3 INT9659 Gene_expression of Il6 3 991 0.78 715.11 265.57
4 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
5 INT2391 Negative_regulation of PTGS1 4 501 0.59 207.62 205.6
6 INT6488 Gene_expression of Tnf 3 484 0.78 339.61 191.58
7 INT9852 Positive_regulation of Gpt 2 563 0.70 364.64 146.82
8 INT14151 Gene_expression of Casp3 1 311 0.78 140.26 120.68
9 INT90 Localization of Gast 1 400 0.81 137.67 113
10 INT27096 Positive_regulation of Nfkb1 1 325 0.70 195.11 109.06
11 INT12476 Negative_regulation of TRPV1 2 124 0.59 47.95 77.98
12 INT6486 Positive_regulation of Tnf 1 168 0.70 123.47 66.05
13 INT17564 Gene_expression of Gpt 4 322 0.75 208.51 60.36
14 INT103924 Positive_regulation of Akt1 1 359 0.69 158.94 60.34
15 INT55344 Gene_expression of Ros1 3 396 0.54 217.64 59.98
16 INT2389 Regulation of PTGS1 1 86 0.61 31.23 28.95
17 INT50490 Regulation of PTGS2 1 80 0.48 39.51 25.85
18 INT2040 Positive_regulation of CYP2B6 1 95 0.69 34.3 25.6
19 INT68758 Positive_regulation of Ros1 3 125 0.46 82.72 25.27
20 INT35711 Positive_regulation of Sdcbp 3 110 0.60 50.45 22.11
21 INT72060 Positive_regulation of Gene_expression of Ros1 3 127 0.41 76.76 20.91
22 INT49985 Transcription of Il6 1 62 0.72 40.13 20.29
23 INT76924 Positive_regulation of Slc17a5 2 71 0.70 41.21 19.31
24 INT49986 Transcription of Tnf 2 25 0.72 18.3 16.22
25 INT14152 Gene_expression of Slc17a5 4 46 0.61 20.01 15.9
26 INT12950 Gene_expression of Cat 3 85 0.75 35.94 15.76
27 INT35120 Gene_expression of Sdcbp 5 68 0.67 21.33 13.96
28 INT60764 Positive_regulation of PPIG 1 39 0.67 17.08 13.48
29 INT18191 Negative_regulation of Cyp3a23/3a1 1 48 0.57 10.21 13.38
30 INT22213 Localization of Gpt 1 52 0.78 34.05 12.94
31 INT11649 Negative_regulation of Positive_regulation of Gpt 1 25 0.59 13.94 10.87
32 INT99505 Gene_expression of Bcl2l1 1 42 0.77 33.12 10.15
33 INT120509 Gene_expression of Cat 1 65 0.77 50.9 9.75
34 INT62166 Positive_regulation of Gene_expression of Gpt 1 64 0.50 39.13 9.69
35 INT35366 Binding of AR 1 87 0.47 30.52 8.9
36 INT5194 Positive_regulation of Lpo 1 63 0.70 26.44 8.37
37 INT12334 Positive_regulation of CYP3A 2 34 0.70 6.77 7.85
38 INT159946 Gene_expression of Mat1a 1 23 0.77 15.33 7.49
39 INT68299 Binding of Tnf 1 17 0.39 12.55 7.49
40 INT138922 Positive_regulation of Stat1 1 57 0.69 28.35 7.2
41 INT37745 Positive_regulation of Gene_expression of Sdcbp 4 22 0.60 5.15 6.02
42 INT124605 Gene_expression of Ifih1 1 16 0.57 7.36 5.33
43 INT108342 Negative_regulation of EPHB2 1 18 0.57 9.48 4.46
44 INT108086 Negative_regulation of AKR1C3 6 17 0.58 7.7 3.99
45 INT156131 Binding of Hand2 1 14 0.25 10.35 3.99
46 INT135016 Positive_regulation of Gene_expression of Slc17a5 1 7 0.55 4.33 3.74
47 INT53388 Negative_regulation of Cyp2c11 1 18 0.53 2.66 3.11
48 INT153946 Localization of Slc17a5 1 8 0.66 4.83 2.93
49 INT79722 Regulation of Cat 2 14 0.62 5.88 2.86
50 INT78146 Gene_expression of AKR1C3 2 24 0.77 5.71 2.77
51 INT88852 Protein_catabolism of Casp3 1 28 0.65 23.57 2.74
52 INT46668 Negative_regulation of Localization of Gpt 1 8 0.42 4.61 2.08
53 INT127649 Regulation of Ifih1 2 6 0.23 4.21 1.92
54 INT159947 Negative_regulation of Gene_expression of Mat1a 1 2 0.42 4.01 1.46
55 INT83659 Negative_regulation of Binding of Tnf 1 3 0.37 1.57 1.42
56 INT122171 Negative_regulation of AKR1C1 3 5 0.59 1.92 1.22
57 INT165800 Positive_regulation of Ddit3 1 17 0.67 11.69 1.21
58 INT52061 Negative_regulation of HSD17B6 1 5 0.57 1.5 1.16
59 INT42504 Negative_regulation of Nox1 1 5 0.43 0.55 0.91
60 INT156966 Negative_regulation of Localization of Slc17a5 1 2 0.34 1.13 0.86
61 INT86370 Regulation of CDH1 1 10 0.54 13.89 0.7
62 INT156060 Regulation of Binding of AR 1 2 0.09 0.42 0.69
63 INT156085 Negative_regulation of AKR1C2 2 3 0.54 0.79 0.66
64 INT156077 Negative_regulation of Akr1c1 2 1 0.09 0.74 0.57
65 INT116925 Binding of AKR1C3 1 2 0.36 0.75 0.56
66 INT140620 Gene_expression of HYOU1 1 5 0.66 3.72 0.54
67 INT97663 Localization of AKR1C2 1 2 0.71 0.43 0.5
68 INT165799 Negative_regulation of Gene_expression of Bcl2l1 1 6 0.41 5.12 0.47
69 INT140616 Positive_regulation of HYOU1 1 7 0.68 5.23 0.45
70 INT163803 Regulation of Gene_expression of Cat 1 3 0.61 1.51 0.33
71 INT156076 Negative_regulation of Localization of Akr1c1 1 1 0.09 0.43 0.27
72 INT156086 Negative_regulation of Localization of AKR1C2 1 1 0.10 0.43 0.27
73 INT156078 Localization of Akr1c1 1 1 0.15 0.43 0.27
74 INT165802 Phosphorylation of Eif2ak2 1 2 0.80 2.71 0.17
75 INT78144 Transcription of AKR1C3 1 4 0.72 1.21 0.13
76 INT165801 Gene_expression of Eif2ak2 1 1 0.58 0.81 0.09
77 INT165794 Phosphorylation of HYOU1 1 1 0.01 0.81 0.09
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