J:Clin. Endocrinol. (Oxf)

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT24388 CRH Positive_regulation of Localization of POMC 8 1 0.51 5.67 3.35
2 INT13729 GHRH Positive_regulation of Localization of GH1 13 2 0.62 0.59 3.2
3 INT21520 Crh Regulation of Pomc 3 1 0.22 0.4 2.45
4 INT18197 Ghrh Positive_regulation of Localization of Ggh 4 1 0.46 0 2.23
5 INT16891 GHRH Regulation of GH1 5 1 0.37 1.94 1.82
6 INT25272 Binding of Ggh and Ghrh 1 1 0.22 0 0.97
7 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 3 1 0.50 0.78 0.86
8 INT16894 Regulation of GHRH Regulation of GH1 2 1 0.37 0 0.72
9 INT45780 GNRH1 Positive_regulation of PLOD1 3 1 0.07 1.02 0.63
10 INT25248 GNRH1 Regulation of CGA 4 1 0.30 1.22 0.62
11 INT45782 Regulation of GNRH1 Positive_regulation of BRD2 1 1 0.06 0.16 0.61
12 INT45781 Regulation of GNRH1 Positive_regulation of PLOD1 1 1 0.06 0.16 0.61
13 INT45779 GNRH1 Positive_regulation of BRD2 1 1 0.07 0.16 0.6
14 INT5132 GNRH1 Regulation of Lhb 2 1 0.08 0 0.52
15 INT44441 GNRH1 Positive_regulation of Localization of FSHR 2 1 0.15 0.86 0.26
16 INT44440 GNRH1 Positive_regulation of Localization of PRL 1 1 0.08 0.19 0.26
17 INT44443 GNRH1 Positive_regulation of Localization of TRH 1 1 0.08 0.19 0.26
18 INT25247 TRH Regulation of CGA 1 1 0.26 0 0.24
19 INT29385 Positive_regulation of Crh Regulation of Pomc 1 1 0.00 0.21 0.06
20 INT61038 GNRH1 Regulation of Prl 1 1 0.03 0 0
21 INT68257 Binding of CALCA and GH1 1 1 0.00 0.54 0
22 INT68256 Binding of GH1 and SCT 1 1 0.04 0.54 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT158 Localization of Prl 33 2431 0.81 378.96 952.2
2 INT2543 Positive_regulation of Calca 1 787 0.70 331.13 592.08
3 INT155 Positive_regulation of Prl 20 1233 0.70 317.93 457.82
4 INT443 Localization of POMC 11 1020 0.81 284.52 443.17
5 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
6 INT157 Positive_regulation of Localization of Prl 14 790 0.70 104.54 374.78
7 INT720 Positive_regulation of POMC 6 807 0.70 237.37 353.83
8 INT162 Regulation of Prl 12 794 0.62 165.01 322.24
9 INT161 Regulation of Localization of Prl 6 615 0.62 65.37 298.66
10 INT1893 Localization of Gh 7 1041 0.79 340.23 256.58
11 INT16868 Gene_expression of Il6 6 807 0.78 499.48 256.57
12 INT738 Regulation of POMC 12 459 0.62 111.19 243.74
13 INT767 Localization of Gnrhr 3 565 0.80 106.68 214.57
14 INT11313 Positive_regulation of Il6 1 526 0.70 331.27 201.59
15 INT528 Gene_expression of Prl 13 693 0.78 217.18 192.2
16 INT159 Negative_regulation of Localization of Prl 1 416 0.59 55.34 171.8
17 INT739 Negative_regulation of POMC 4 358 0.59 102.28 166.77
18 INT5127 Localization of Lhb 14 488 0.80 50.48 162.66
19 INT3448 Positive_regulation of Gh 4 521 0.69 180.03 161.18
20 INT812 Localization of INS 3 1026 0.81 515.6 145.31
21 INT425 Localization of PRL 16 455 0.81 189.64 144.8
22 INT5497 Positive_regulation of Crh 2 299 0.70 125.54 131.14
23 INT695 Binding of POMC 5 304 0.48 56.66 126.85
24 INT252 Localization of GH1 18 529 0.80 227.4 122.05
25 INT6128 Positive_regulation of Localization of POMC 1 256 0.70 68.77 121.64
26 INT7395 Localization of GNRH1 5 399 0.81 62.88 117.68
27 INT1438 Localization of Pomc 1 360 0.81 101.26 116.47
28 INT1793 Localization of CGA 7 379 0.81 67.38 114.69
29 INT90 Localization of Gast 1 400 0.81 137.67 113
30 INT1530 Regulation of Gh 8 382 0.61 115.96 112.47
31 INT3038 Gene_expression of INS 2 1583 0.78 1174.16 107.01
32 INT915 Positive_regulation of PRL 6 342 0.70 141.96 104.31
33 INT1898 Regulation of Crh 2 220 0.62 61.33 102.64
34 INT397 Localization of SST 1 232 0.81 58.05 101.19
35 INT5865 Positive_regulation of Localization of Gh 4 282 0.69 84.86 93.5
36 INT203 Positive_regulation of Pomc 2 257 0.70 90.56 92.84
37 INT214 Localization of AVP 12 370 0.81 208.51 91.09
38 INT1639 Negative_regulation of OPRM1 1 107 0.59 13.86 90.37
39 INT914 Positive_regulation of GH1 15 292 0.69 100.7 84.91
40 INT1309 Positive_regulation of Localization of Gnrhr 4 152 0.69 24.25 81.56
41 INT1498 Gene_expression of Gh 9 521 0.75 220.84 81.16
42 INT148 Positive_regulation of Gnrhr 5 182 0.70 47.44 79.64
43 INT2893 Localization of Oxt 3 219 0.80 28.96 79.43
44 INT920 Localization of PLOD1 13 223 0.81 42.25 78.7
45 INT1497 Negative_regulation of Gh 4 415 0.59 192.95 74.71
46 INT5128 Positive_regulation of Lhb 9 232 0.69 44.23 71.26
47 INT1376 Binding of Trh 1 121 0.48 20 69.86
48 INT2123 Positive_regulation of Gnrh1 1 209 0.70 24.2 68.97
49 INT19511 Localization of Il6 2 212 0.81 118.17 67.67
50 INT462 Regulation of Pomc 4 157 0.62 41.67 67.27
51 INT253 Regulation of PRL 8 184 0.62 47.27 65.79
52 INT5095 Localization of Ghrh 2 185 0.81 28.09 62.08
53 INT1437 Negative_regulation of Pomc 2 132 0.59 35.22 60.97
54 INT1794 Regulation of Localization of CGA 5 136 0.57 13.39 59.07
55 INT5710 Negative_regulation of Localization of Lhb 1 146 0.57 20.51 58.33
56 INT5453 Regulation of Localization of POMC 4 114 0.62 20.56 56.34
57 INT19 Regulation of Gnrhr 2 131 0.62 36.4 55.66
58 INT1579 Gene_expression of PRL 1 279 0.78 119.2 55.41
59 INT4241 Regulation of CALCA 1 87 0.62 28.19 55.29
60 INT251 Regulation of INS 2 398 0.62 232.47 55.04
61 INT49993 Positive_regulation of Gene_expression of Il6 2 149 0.70 88.07 53.78
62 INT1456 Regulation of Oprl1 1 61 0.62 19.5 52.87
63 INT249 Localization of GHRH 6 215 0.80 78.02 51.87
64 INT5118 Regulation of SST 1 97 0.62 34.35 51.74
65 INT921 Regulation of GH1 8 172 0.60 52.88 51.04
66 INT6299 Regulation of Localization of Lhb 4 104 0.61 8.98 48.79
67 INT17881 Gene_expression of LEP 1 278 0.78 221.61 48.31
68 INT654 Localization of REN 1 250 0.81 75.12 47.86
69 INT671 Positive_regulation of Cea 1 221 0.69 164.5 47.79
70 INT847 Regulation of Lhb 10 131 0.61 22.08 46.54
71 INT683 Positive_regulation of AVP 2 173 0.70 74.55 46.41
72 INT531 Gene_expression of GH1 5 376 0.75 193.45 46.24
73 INT1322 Positive_regulation of Localization of INS 2 293 0.70 120.86 45.98
74 INT1894 Negative_regulation of Localization of Gh 1 168 0.58 64.12 43.56
75 INT5130 Regulation of GNRH1 1 139 0.62 31.95 42.08
76 INT3933 Positive_regulation of PLOD1 8 128 0.70 30.76 42.03
77 INT5454 Localization of CRH 1 124 0.79 79.18 41.53
78 INT957 Positive_regulation of GHRH 2 136 0.70 36.84 40.52
79 INT918 Positive_regulation of Localization of PRL 10 90 0.70 23.97 40.3
80 INT685 Regulation of AVP 4 124 0.62 34.9 39.91
81 INT1596 Negative_regulation of Oprl1 3 61 0.57 13.5 38.41
82 INT916 Regulation of Localization of PRL 2 92 0.62 22.98 38.13
83 INT5711 Positive_regulation of Localization of Lhb 2 90 0.70 10.92 36.76
84 INT3253 Negative_regulation of Localization of INS 1 205 0.59 130.39 36.61
85 INT2296 Positive_regulation of Gene_expression of Prl 2 137 0.70 36.96 35.39
86 INT255 Regulation of Localization of GH1 2 89 0.62 18.71 35.3
87 INT326 Gene_expression of Gnrhr 2 105 0.76 35.87 34.93
88 INT692 Negative_regulation of SST 1 72 0.59 28.68 34.52
89 INT1116 Regulation of Ren 1 103 0.62 27.66 33.26
90 INT248 Positive_regulation of Localization of GH1 9 137 0.69 49.25 32.92
91 INT5868 Positive_regulation of GNRH1 1 122 0.69 20.96 32.8
92 INT913 Regulation of Localization of PLOD1 7 71 0.62 8.64 32.72
93 INT985 Negative_regulation of GH1 10 213 0.57 89.53 32.39
94 INT3117 Regulation of Oxt 4 103 0.61 17.93 32.28
95 INT7396 Regulation of Localization of GNRH1 2 81 0.62 6.57 31.31
96 INT7975 Regulation of PLOD1 4 97 0.62 20.9 30.51
97 INT5100 Positive_regulation of Ghrh 1 100 0.64 24.2 30.21
98 INT7397 Negative_regulation of Localization of GNRH1 2 86 0.59 15.45 29.78
99 INT7412 Positive_regulation of SST 1 71 0.70 24.44 29.48
100 INT1196 Positive_regulation of Positive_regulation of POMC 1 51 0.70 15.99 28.58
101 INT7035 Regulation of CGA 1 87 0.45 29.04 28.45
102 INT5135 Negative_regulation of GNRH1 3 106 0.58 36.63 27.71
103 INT2408 Regulation of CCK 1 37 0.61 10.01 26.66
104 INT1638 Negative_regulation of PLOD1 2 92 0.59 21.69 26.61
105 INT9682 Positive_regulation of IGF1 4 238 0.70 120.03 26.36
106 INT2261 Gene_expression of Lhb 6 121 0.77 42.78 26.04
107 INT7394 Positive_regulation of Localization of GNRH1 1 67 0.69 7.22 25.29
108 INT2614 Gene_expression of CGA 1 187 0.78 105.89 24.77
109 INT2140 Regulation of REN 1 104 0.62 28.24 24.49
110 INT3028 Negative_regulation of Oxt 1 76 0.58 18.52 24.4
111 INT5131 Gene_expression of GNRH1 2 109 0.78 28.79 23.94
112 INT7113 Negative_regulation of Localization of CGA 1 71 0.51 17.7 23.42
113 INT250 Regulation of GHRH 1 65 0.61 17.46 23.19
114 INT956 Negative_regulation of PRL 1 94 0.59 42.72 23.01
115 INT917 Positive_regulation of Localization of PLOD1 1 51 0.69 8.53 22.87
116 INT4612 Positive_regulation of Localization of CGA 1 64 0.64 8.51 22.39
117 INT693 Negative_regulation of Localization of SST 1 46 0.59 8.57 21.75
118 INT1644 Regulation of FSHR 2 77 0.55 15.62 21.49
119 INT2894 Negative_regulation of Localization of Oxt 1 43 0.58 4.59 20.85
120 INT6127 Regulation of Localization of AVP 5 60 0.62 15.12 20.84
121 INT955 Gene_expression of GHRH 11 126 0.78 59.91 20.74
122 INT5372 Localization of LHB 2 55 0.68 9.47 19
123 INT11628 Regulation of Localization of Pomc 1 44 0.61 10.46 18.66
124 INT13454 Positive_regulation of Positive_regulation of Gh 1 49 0.68 14.53 18.49
125 INT9179 Positive_regulation of Localization of Ghrh 1 42 0.70 7.05 18.1
126 INT1642 Negative_regulation of Localization of PLOD1 2 40 0.58 10.67 17.95
127 INT871 Negative_regulation of Gene_expression of Prl 3 53 0.58 18.89 17.79
128 INT1578 Negative_regulation of Localization of PRL 2 52 0.59 20.62 17.18
129 INT10841 Positive_regulation of Gene_expression of Gh 6 101 0.59 45.39 16.96
130 INT213 Negative_regulation of Localization of AVP 1 46 0.59 19.78 16.79
131 INT6129 Positive_regulation of Localization of AVP 2 63 0.70 30.44 16.64
132 INT984 Positive_regulation of Localization of GHRH 2 58 0.70 12.66 16.51
133 INT1000 Localization of Ggh 4 31 0.75 2.74 16.41
134 INT1261 Localization of Adh1 1 63 0.81 19.36 16.09
135 INT62681 Negative_regulation of LEP 1 93 0.59 66.97 15.77
136 INT912 Localization of FSHR 1 91 0.79 23.61 15.58
137 INT7970 Gene_expression of PLOD1 1 120 0.71 44.42 15.54
138 INT129 Localization of OXTR 4 51 0.80 11.08 15.36
139 INT26538 Positive_regulation of FSHR 1 103 0.69 30.95 15.33
140 INT75908 Regulation of LEP 2 77 0.60 60.16 15.19
141 INT11918 Localization of CGB 6 35 0.51 8.21 15.01
142 INT10340 Regulation of Localization of Oxt 2 30 0.60 2.55 14.3
143 INT8798 Positive_regulation of Csrp1 1 61 0.69 63.86 14.14
144 INT8089 Binding of Gnrh1 1 47 0.48 10.04 13.99
145 INT55256 Negative_regulation of Localization of Il6 2 38 0.58 16.12 13.67
146 INT16530 Gene_expression of Ghrh 1 45 0.77 6.22 13.44
147 INT4145 Gene_expression of FSHR 1 124 0.77 44.98 13.04
148 INT9678 Positive_regulation of Positive_regulation of GH1 2 32 0.68 8.14 12.97
149 INT3040 Gene_expression of MIA3 1 81 0.24 53.61 12.62
150 INT7234 Binding of GNRH1 1 43 0.47 21.59 12.36
151 INT744 Positive_regulation of PTH 2 130 0.70 95.02 11.7
152 INT83894 Positive_regulation of TRPM8 1 37 0.70 18.28 11.7
153 INT50933 Transcription of Il6 1 38 0.72 24.31 11.58
154 INT987 Localization of TRH 1 37 0.78 10.53 11.1
155 INT9946 Regulation of Localization of LHB 2 27 0.52 2.47 11.08
156 INT2407 Regulation of GAST 1 26 0.62 5.31 10.04
157 INT6516 Positive_regulation of BGLAP 1 45 0.67 26.61 9.9
158 INT1372 Regulation of Localization of REN 1 50 0.62 5.76 9.81
159 INT4494 Regulation of GCG 1 41 0.45 18.38 9.68
160 INT34777 Localization of IGF1 1 82 0.80 42.68 8.62
161 INT13346 Regulation of Localization of CGB 3 18 0.30 1.29 8.32
162 INT26815 Regulation of OXT 4 15 0.46 5.38 8.31
163 INT12292 Negative_regulation of Positive_regulation of GH1 1 22 0.58 5.02 8.28
164 INT4487 Positive_regulation of Positive_regulation of PRL 1 27 0.70 8.06 8.09
165 INT6957 Positive_regulation of OXTR 1 38 0.70 6.55 7.81
166 INT19302 Localization of OXT 9 31 0.79 3.39 6.92
167 INT6512 Gene_expression of PTH 1 103 0.77 76.29 6.33
168 INT11826 Positive_regulation of LDLR 1 62 0.62 45.09 6.21
169 INT10675 Gene_expression of DBI 1 28 0.67 19.74 6.07
170 INT9683 Binding of GH1 2 57 0.47 21.14 5.99
171 INT1002 Regulation of Localization of Ggh 1 10 0.58 0.63 5.98
172 INT7361 Binding of Ghrh 2 13 0.45 1.37 5.44
173 INT13735 Negative_regulation of Regulation of GH1 1 14 0.42 4.35 5.39
174 INT4342 Localization of ALPP 1 27 0.69 15.19 5.32
175 INT21067 Regulation of Regulation of PRL 1 11 0.60 2 5.31
176 INT5126 Positive_regulation of Positive_regulation of Lhb 1 16 0.48 2.12 5.23
177 INT7479 Positive_regulation of Ggh 1 13 0.62 5.71 5.02
178 INT19900 Binding of GHRH 1 22 0.37 5.75 5
179 INT49130 Positive_regulation of IGFBP3 2 49 0.63 27.55 4.78
180 INT4146 Binding of SHBG 1 49 0.47 31 4.71
181 INT68260 Localization of BGLAP 1 34 0.78 16.04 4.63
182 INT19008 Positive_regulation of Positive_regulation of Ghrh 1 15 0.49 2.4 4.55
183 INT3230 Negative_regulation of Negative_regulation of Prl 1 9 0.43 1.85 4.41
184 INT10849 Negative_regulation of OXT 2 14 0.48 2.51 4.19
185 INT19301 Regulation of Regulation of AVP 1 9 0.45 3.15 4.09
186 INT19300 Positive_regulation of OXT 1 34 0.43 4.43 4.07
187 INT16235 Positive_regulation of CGB 2 27 0.70 15.71 4.06
188 INT484 Negative_regulation of ADRB2 1 13 0.59 2.85 3.94
189 INT9677 Negative_regulation of Gene_expression of GH1 1 46 0.48 23.32 3.68
190 INT5345 Positive_regulation of BRD2 1 14 0.67 6.72 3.43
191 INT20179 Positive_regulation of Regulation of Gh 4 12 0.54 3.99 3.42
192 INT7224 Positive_regulation of Gene_expression of Lhb 1 18 0.45 10.22 3.4
193 INT15609 Positive_regulation of Gene_expression of GNRH1 1 17 0.49 5.15 3.34
194 INT22389 Regulation of MLN 1 9 0.61 4.39 3.08
195 INT30077 Positive_regulation of Localization of CGB 2 5 0.34 0.42 3.07
196 INT28715 Negative_regulation of Regulation of Crh 1 7 0.43 0.97 3.06
197 INT8657 Binding of DBI 2 12 0.42 2.22 3.04
198 INT10830 Regulation of Apoa1 1 11 0.44 15.1 3.04
199 INT94947 Positive_regulation of Transcription of Il6 1 9 0.67 6.91 3.04
200 INT23763 Regulation of Localization of CRH 1 6 0.48 0.22 3.04
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