J:Clin Pharmacokinet

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT115729 Binding of CYP3A7 and CYP3A4 1 1 0.44 0.05 0.23
2 INT85828 CYP3A4 Negative_regulation of CYP2D6 1 1 0.47 0.06 0.16
3 INT37489 Binding of ADRA1D and Alb 1 1 0.34 0.84 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT49750 Negative_regulation of CPOX 1 735 0.58 360.06 274.19
2 INT626 Localization of CALCA 2 289 0.81 125.39 221.15
3 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
4 INT15913 Negative_regulation of CYP2D6 10 174 0.59 22.45 70.91
5 INT546 Binding of ALB 20 311 0.48 85.98 60.14
6 INT50405 Negative_regulation of CYP3A4 4 238 0.59 53.65 51.51
7 INT7093 Negative_regulation of CYP2B6 1 146 0.58 37.3 48.39
8 INT56870 Gene_expression of CYP2D6 1 87 0.78 8.83 37.53
9 INT10796 Gene_expression of CYP2B6 1 131 0.77 30.14 35.27
10 INT4403 Binding of CYP2B6 5 113 0.48 21.17 33.83
11 INT234 Binding of Alb 14 151 0.48 52.34 32.97
12 INT10797 Binding of CYP2D6 4 86 0.48 15.09 31.16
13 INT10285 Binding of ADRA1D 8 102 0.47 25.82 31.11
14 INT5298 Negative_regulation of MTHFS 3 70 0.57 27.07 28.11
15 INT14690 Localization of CSF2 1 124 0.80 85.17 27.26
16 INT3760 Positive_regulation of ALB 1 142 0.70 87.46 26.7
17 INT2040 Positive_regulation of CYP2B6 4 95 0.69 34.3 25.6
18 INT825 Negative_regulation of ADRA1D 1 54 0.58 20.25 22.78
19 INT39914 Negative_regulation of Cyp1a2 3 44 0.58 10.04 22
20 INT60779 Negative_regulation of CYP3A 9 63 0.59 8.38 21.27
21 INT3593 Gene_expression of ADRA1D 1 70 0.75 29.48 20.87
22 INT6699 Positive_regulation of ADRA1D 3 65 0.70 22.72 20.31
23 INT5137 Binding of pCA 1 45 0.47 16.91 18.47
24 INT68347 Negative_regulation of Cyp2d4 1 34 0.58 7.62 18.35
25 INT667 Negative_regulation of Hrh2 1 38 0.58 18.11 18.01
26 INT50403 Negative_regulation of CYP2C19 5 55 0.59 8.97 17.79
27 INT50404 Negative_regulation of CYP1A2 2 49 0.59 8.61 17.35
28 INT20336 Positive_regulation of CYP2E1 5 48 0.70 19.26 15.66
29 INT2630 Positive_regulation of Shbg 1 134 0.70 65.26 15.19
30 INT663 Negative_regulation of Adrb3 1 55 0.59 15.95 14.68
31 INT7523 Regulation of ADRA1D 2 42 0.45 11.63 14.52
32 INT67855 Negative_regulation of PPIG 2 64 0.57 17.83 13.54
33 INT60764 Positive_regulation of PPIG 4 39 0.67 17.08 13.48
34 INT50580 Binding of PPIG 5 39 0.36 11.17 12.34
35 INT70877 Gene_expression of PPIG 4 72 0.75 22.39 10.93
36 INT83886 Negative_regulation of HMOX2 6 27 0.43 11.69 10.78
37 INT55418 Regulation of CYP2D6 1 29 0.61 1.83 10.21
38 INT47860 Negative_regulation of Cyp1a2 1 20 0.57 6.06 10
39 INT68372 Regulation of CYP2C9 2 28 0.62 5.64 9.53
40 INT20664 Binding of ACE 2 60 0.48 35.27 9.16
41 INT860 Regulation of ALB 2 48 0.60 25.11 8.95
42 INT13467 Positive_regulation of ABCB1 1 36 0.68 9.68 8.95
43 INT82839 Negative_regulation of ABCB1 2 61 0.59 16.09 8.83
44 INT66819 Binding of CYP2C9 2 41 0.48 8.23 8.76
45 INT61599 Positive_regulation of CYP2C9 1 43 0.69 11.1 8.33
46 INT12334 Positive_regulation of CYP3A 4 34 0.70 6.77 7.85
47 INT17867 Positive_regulation of Cyp1a2 1 39 0.69 2.58 7.57
48 INT57922 Gene_expression of CYP2C9 1 65 0.78 22.24 7.53
49 INT7743 Binding of Hrh2 1 19 0.47 7.75 7.11
50 INT63057 Regulation of CYP3A4 1 31 0.61 5.75 6.92
51 INT12333 Regulation of CYP3A 1 18 0.62 2.25 6.74
52 INT2039 Regulation of CYP2B6 1 30 0.60 7.75 6.43
53 INT48393 Positive_regulation of Localization of CSF2 1 14 0.60 8.92 6.1
54 INT57719 Localization of GPM6A 1 7 0.44 0.95 5.97
55 INT20331 Positive_regulation of CYP1A2 2 31 0.69 8.6 5.92
56 INT65135 Binding of CYP2C19 3 17 0.48 1.82 5.2
57 INT2435 Negative_regulation of Cyp1a1 1 15 0.58 3.32 5.16
58 INT60252 Binding of HIVEP1 1 59 0.32 65.12 5.06
59 INT28145 Binding of PAPPA 5 26 0.48 7.4 4.96
60 INT12412 Binding of MPG 3 21 0.47 3.92 4.94
61 INT79709 Regulation of M1 1 13 0.24 4.8 4.9
62 INT95538 Localization of CYP2D6 1 21 0.81 5.69 4.73
63 INT50581 Regulation of PPIG 2 26 0.55 8.96 4.32
64 INT80892 Negative_regulation of Hmox2 1 10 0.55 4.76 3.64
65 INT27694 Positive_regulation of Positive_regulation of ADRA1D 1 10 0.70 1.52 3.57
66 INT19538 Positive_regulation of MPG 1 8 0.67 3.21 3.57
67 INT19211 Binding of Shbg 3 35 0.48 16.29 3.31
68 INT22949 Gene_expression of CCBE1 1 8 0.19 4.27 3.25
69 INT3682 Binding of Ppr1 1 10 0.42 1.87 2.96
70 INT45112 Positive_regulation of PRB1 2 20 0.60 6.49 2.85
71 INT71794 Binding of SERPINC1 1 17 0.39 10.5 2.64
72 INT9764 Gene_expression of Adrb3 1 10 0.62 4.14 2.33
73 INT56337 Regulation of Cyp1a2 2 8 0.27 1.09 2.33
74 INT6521 Negative_regulation of Gene_expression of ADRA1D 1 4 0.57 3.19 2.14
75 INT36267 Positive_regulation of CYP1A1 3 29 0.69 11.09 2.01
76 INT11905 Protein_catabolism of EPO 1 6 1.00 2.36 2
77 INT101410 Negative_regulation of Positive_regulation of CYP2C9 1 5 0.42 0.23 1.96
78 INT67089 Positive_regulation of Ugt1a6a 1 4 0.27 0.34 1.9
79 INT48673 Negative_regulation of IGKV2D-26 1 4 0.42 0.24 1.59
80 INT9864 Positive_regulation of B3gat3 1 2 0.11 0.37 1.49
81 INT83247 Positive_regulation of SLC45A2 2 5 0.67 1.81 1.18
82 INT125541 Transcription of CYP3A4 1 7 0.69 2.14 1.02
83 INT60458 Localization of G2E3 1 1 0.06 0 0.91
84 INT53852 Binding of Fabp1 1 1 0.02 0.21 0.85
85 INT70818 Negative_regulation of Adh7 1 2 0.16 1.04 0.79
86 INT93574 Protein_catabolism of CYP2B6 1 3 0.96 0.16 0.75
87 INT83246 Regulation of Positive_regulation of PPIG 3 1 0.44 1.61 0.72
88 INT9903 Gene_expression of CYB5A 1 9 0.37 2.78 0.53
89 INT99698 Positive_regulation of CD53 1 1 0.01 0.14 0.45
90 INT163516 Negative_regulation of Positive_regulation of PRB1 1 1 0.15 0.08 0.45
91 INT57326 Regulation of Positive_regulation of CYP2B6 2 4 0.44 2.08 0.43
92 INT44273 Binding of MTHFS 1 3 0.29 0.81 0.41
93 INT83287 Regulation of Gene_expression of PPIG 1 4 0.46 1.74 0.36
94 INT84396 Positive_regulation of Positive_regulation of Cyp1a2 1 2 0.24 0.22 0.34
95 INT83288 Negative_regulation of NEU4 1 12 0.51 3.58 0.28
96 INT44766 Negative_regulation of Binding of ADRA1D 1 2 0.42 0.71 0.27
97 INT142355 Gene_expression of Tpmt 2 3 0.70 1.08 0.26
98 INT164226 Regulation of TBX3 1 1 0.23 0.57 0.26
99 INT83243 Positive_regulation of Positive_regulation of SLC45A2 2 1 0.67 1.5 0.21
100 INT93575 Regulation of Binding of PPIG 1 1 0.44 0.15 0.18
101 INT44087 Regulation of Negative_regulation of Adrb3 1 1 0.31 0.28 0.15
102 INT78424 Positive_regulation of CYP4Z1 1 1 0.02 0.22 0.13
103 INT68218 Regulation of Positive_regulation of CYP1A1 2 3 0.45 2.35 0.1
104 INT23647 Negative_regulation of CDA 1 3 0.38 1.48 0.08
105 INT61959 Regulation of IGKV5-2 1 2 0.17 0.07 0.07
106 INT83244 Regulation of Positive_regulation of CYP1A2 2 1 0.43 1.18 0
107 INT83242 Regulation of Positive_regulation of SLC45A2 2 1 0.44 1.18 0
108 INT127937 Negative_regulation of Positive_regulation of CYP3A 1 1 0.43 0 0
109 INT83289 Binding of NEU4 1 1 0.02 0.1 0
110 INT83245 Regulation of Positive_regulation of CYP2E1 2 1 0.44 1.19 0
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