J:Clinical Science (London, England : 1979)

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT246938 Binding of Tlr4 and Tlr2 3 1 0.39 2.88 0.46
2 INT139502 Binding of Crp and Tnf 1 1 0.03 0.48 0.19
3 INT349286 Serpina1a Negative_regulation of Prtn3 1 1 0.11 0.4 0.03
4 INT349287 A2m Negative_regulation of Prtn3 1 1 0.00 0.4 0.03
5 INT139004 Mtpn Regulation of NFKB1 1 1 0.33 0.55 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
2 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
3 INT68684 Gene_expression of VEGFA 2 2371 0.78 1742.52 259.2
4 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
5 INT48955 Gene_expression of Nos2 1 753 0.78 403.87 208.08
6 INT9132 Negative_regulation of Prkcg 1 279 0.59 88.05 203.47
7 INT49441 Negative_regulation of Cpox 8 494 0.59 303.22 177.46
8 INT15516 Gene_expression of Crp 2 711 0.77 615.33 173.09
9 INT66280 Gene_expression of Nos2 3 534 0.78 330.78 157.07
10 INT812 Localization of INS 38 1026 0.81 515.6 145.31
11 INT48953 Positive_regulation of Nos2 1 486 0.70 239.85 131.87
12 INT49439 Gene_expression of Cpox 9 508 0.73 326.97 130.17
13 INT7533 Gene_expression of Tlr4 27 720 0.78 343.22 121.57
14 INT3038 Gene_expression of INS 1 1583 0.78 1174.16 107.01
15 INT69440 Gene_expression of ROS1 6 752 0.78 477.64 103.83
16 INT74058 Gene_expression of Nos1 1 260 0.78 80.04 95.71
17 INT77435 Positive_regulation of Nos2 1 343 0.70 208.49 91.43
18 INT82448 Gene_expression of S100a8 2 246 0.77 236.72 84.02
19 INT68682 Positive_regulation of VEGFA 3 640 0.70 454.14 81.65
20 INT79494 Positive_regulation of Gene_expression of VEGFA 2 577 0.70 442.94 69.73
21 INT1951 Positive_regulation of Tlr4 8 345 0.70 176.99 62.42
22 INT48232 Gene_expression of MMP1 1 245 0.78 96.31 57.72
23 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
24 INT49017 Negative_regulation of Gene_expression of Nos2 1 169 0.59 80.64 52.67
25 INT1199 Positive_regulation of INS 1 579 0.70 399.64 50.43
26 INT1322 Positive_regulation of Localization of INS 23 293 0.70 120.86 45.98
27 INT2774 Binding of Crp 1 241 0.48 195.89 44.39
28 INT69437 Positive_regulation of ROS1 1 328 0.58 222.83 40.56
29 INT3252 Negative_regulation of INS 3 428 0.59 271.65 39.52
30 INT3253 Negative_regulation of Localization of INS 6 205 0.59 130.39 36.61
31 INT2274 Regulation of Localization of INS 3 101 0.62 41.55 34.79
32 INT74563 Positive_regulation of Gene_expression of ROS1 1 258 0.61 168.18 34.08
33 INT16960 Gene_expression of Crp 2 166 0.76 116.21 34.07
34 INT81289 Positive_regulation of Gene_expression of Tlr4 4 192 0.69 104.5 33.89
35 INT67039 Positive_regulation of Cpox 1 144 0.65 98.4 33.77
36 INT52350 Gene_expression of CD14 1 184 0.75 71.37 33.13
37 INT92837 Negative_regulation of Gene_expression of Nos2 1 116 0.59 59.67 31.82
38 INT29503 Gene_expression of Mmp2 2 95 0.77 56.92 31.68
39 INT48693 Regulation of VEGFA 2 268 0.62 191.88 31.52
40 INT56809 Binding of Tlr4 1 184 0.48 106.02 31.18
41 INT86295 Gene_expression of Mmp2 1 114 0.76 73.68 24.25
42 INT142594 Gene_expression of Tlr2 18 165 0.78 139.73 22.26
43 INT78057 Localization of Tlr4 5 140 0.77 67.75 21.72
44 INT7535 Negative_regulation of Tlr4 3 111 0.56 56.84 21.37
45 INT48692 Binding of VEGFA 2 345 0.48 210.3 21.31
46 INT101188 Gene_expression of Rela 1 81 0.56 23.43 19.15
47 INT61519 Gene_expression of Mpo 2 112 0.78 89.29 18.22
48 INT78990 Regulation of Cpox 1 72 0.57 35.22 18.16
49 INT132997 Localization of Mmp9 2 59 0.80 45.9 17.61
50 INT77433 Regulation of Gene_expression of Nos2 1 49 0.62 35.07 16.33
51 INT22579 Localization of Efs 2 35 0.65 2.77 16.05
52 INT61117 Gene_expression of Ppara 1 158 0.68 69.3 15.98
53 INT43906 Regulation of Tlr4 4 71 0.53 35.18 15.49
54 INT81627 Gene_expression of Fas 1 120 0.78 115.51 15.36
55 INT67641 Negative_regulation of Gene_expression of Tlr4 1 90 0.58 46 14.6
56 INT152729 Negative_regulation of Gene_expression of S100a8 1 33 0.42 32.25 13.64
57 INT142593 Positive_regulation of Tlr2 3 85 0.70 75.9 13.62
58 INT69436 Negative_regulation of Gene_expression of ROS1 1 81 0.38 46.58 12.22
59 INT112003 Localization of ROS1 1 94 0.73 66.32 12.16
60 INT83611 Negative_regulation of Gene_expression of Cpox 6 55 0.29 31.09 11.5
61 INT4605 Negative_regulation of Gene_expression of INS 2 220 0.58 139.66 10.75
62 INT94004 Negative_regulation of Lox 2 31 0.59 13.76 10.45
63 INT94784 Binding of ROS1 1 113 0.40 71.57 10.26
64 INT26795 Gene_expression of Mtpn 1 44 0.62 27.66 8.62
65 INT127378 Localization of Mpo 1 21 0.78 26.36 8.28
66 INT50290 Binding of Cpox 1 29 0.27 17.19 8.01
67 INT4022 Negative_regulation of PLA2G1B 1 30 0.59 10.41 7.58
68 INT68299 Binding of Tnf 1 17 0.39 12.55 7.49
69 INT1950 Positive_regulation of Positive_regulation of Tlr4 1 38 0.49 20.17 7.14
70 INT170922 Binding of Ppara 1 59 0.45 28.45 6.7
71 INT142596 Positive_regulation of Gene_expression of Tlr2 1 42 0.69 38.41 6.67
72 INT103760 Regulation of Gene_expression of Tlr4 1 35 0.59 16.26 5.95
73 INT49440 Localization of Cpox 1 27 0.53 11.26 5.79
74 INT142595 Negative_regulation of Tlr2 2 24 0.52 19.17 5.43
75 INT174688 Binding of Tlr2 1 45 0.42 36.65 5.25
76 INT85653 Regulation of Gene_expression of Cpox 1 24 0.24 20.55 5.22
77 INT89142 Gene_expression of Lox 2 28 0.67 15.36 5.2
78 INT157622 Positive_regulation of Localization of Tlr4 1 34 0.48 22.63 5.09
79 INT19993 Negative_regulation of Ren1 1 43 0.58 20.89 5.04
80 INT51983 Negative_regulation of Prtn3 3 23 0.34 12.54 5
81 INT22580 Negative_regulation of Localization of Efs 1 9 0.25 0.24 4.24
82 INT81628 Positive_regulation of Gene_expression of Fas 1 32 0.67 38.13 4.23
83 INT86293 Positive_regulation of Gene_expression of Mmp2 1 21 0.64 11.69 3.79
84 INT140555 Positive_regulation of Localization of ROS1 1 29 0.55 23.82 3.14
85 INT185315 Transcription of Tlr4 1 24 0.69 8.65 2.93
86 INT58527 Gene_expression of Prtn3 6 20 0.71 15.99 2.9
87 INT110039 Positive_regulation of Nppb 1 38 0.53 34.54 2.88
88 INT114753 Negative_regulation of Gene_expression of Crp 1 7 0.42 4.79 2.77
89 INT104290 Gene_expression of Ucp2 4 21 0.78 12.81 2.34
90 INT204775 Regulation of Tlr2 3 21 0.41 13.6 2.18
91 INT117457 Positive_regulation of Gene_expression of Lox 1 9 0.39 6.97 2.08
92 INT46332 Binding of Mmp2 1 10 0.34 5.63 2
93 INT94001 Positive_regulation of Lox 1 15 0.60 7.46 1.92
94 INT228195 Negative_regulation of Gene_expression of Tlr2 1 14 0.40 12.17 1.74
95 INT78005 Negative_regulation of Binding of Cpox 1 7 0.31 3.19 1.7
96 INT129534 Gene_expression of Nppb 2 19 0.58 23.68 1.6
97 INT17885 Negative_regulation of YWHAZ 1 6 0.56 2.74 1.58
98 INT204563 Binding of Mpo 1 16 0.37 12.1 1.56
99 INT113785 Negative_regulation of Eef1a2 1 15 0.31 1.33 1.48
100 INT174683 Transcription of Tlr2 1 12 0.58 5.95 1.4
101 INT246928 Negative_regulation of Myd88 1 12 0.38 6.16 1.3
102 INT221131 Localization of Tlr2 3 17 0.80 13.82 1.28
103 INT202476 Positive_regulation of Gene_expression of Rela 1 10 0.34 3.65 1.22
104 INT183046 Transcription of INS 2 25 0.70 11.14 1.13
105 INT104289 Positive_regulation of Gene_expression of Ucp2 2 7 0.59 4.46 1.13
106 INT11109 Positive_regulation of Serpina1a 1 5 0.68 4.97 1.12
107 INT182533 Positive_regulation of Prtn3 4 6 0.37 5.99 1.06
108 INT133175 Negative_regulation of Scd2 2 2 0.11 0.31 0.93
109 INT294726 Positive_regulation of Lts1 1 5 0.49 4.06 0.87
110 INT161754 Transcription of Ppara 2 10 0.52 4.06 0.84
111 INT164669 Positive_regulation of Nucb2 1 3 0.31 1.67 0.84
112 INT121858 Negative_regulation of PI3 1 7 0.43 3.16 0.8
113 INT104291 Positive_regulation of Ucp2 1 7 0.70 2.71 0.75
114 INT328226 Negative_regulation of Positive_regulation of Cpox 1 3 0.11 1.49 0.73
115 INT228188 Regulation of Gene_expression of Tlr2 2 5 0.45 6.96 0.71
116 INT227274 Transcription of Ucp2 2 10 0.67 9.79 0.54
117 INT246926 Negative_regulation of Transcription of Tlr4 1 3 0.41 1.78 0.49
118 INT261557 Positive_regulation of Localization of Cpox 1 2 0.04 0.17 0.45
119 INT142324 Gene_expression of Ncf1 2 19 0.75 10.8 0.41
120 INT329881 Positive_regulation of Transcription of Ucp2 1 6 0.57 4.49 0.41
121 INT183066 Positive_regulation of Transcription of INS 1 8 0.49 5.31 0.34
122 INT8540 Gene_expression of Serpina1a 4 5 0.66 3.99 0.34
123 INT131019 Binding of T2DM 1 6 0.47 6.97 0.31
124 INT207293 Negative_regulation of Negative_regulation of INS 1 12 0.49 6 0.26
125 INT188511 Positive_regulation of Transcription of Ppara 1 2 0.22 0.22 0.26
126 INT250515 Regulation of Gene_expression of Ucp2 1 3 0.39 1.88 0.22
127 INT215147 Regulation of Prtn3 1 3 0.26 1.32 0.22
128 INT334978 Binding of Nucb2 1 2 0.07 0.26 0.22
129 INT238100 Localization of Prtn3 1 3 0.60 1.41 0.21
130 INT110040 Binding of Nppb 2 9 0.18 8.91 0.19
131 INT283299 Transcription of Serpina1a 1 2 0.17 1.28 0.18
132 INT344394 Binding of Ucp2 1 4 0.36 1.54 0.16
133 INT259615 Binding of Prtn3 2 2 0.24 2.48 0.16
134 INT229014 Binding of Ppard 1 6 0.21 2.79 0.14
135 INT227266 Regulation of Transcription of Ucp2 1 2 0.51 2.44 0.12
136 INT11110 Binding of Serpina1a 3 4 0.17 3.19 0.1
137 INT236926 Binding of Ffar1 1 3 0.07 0.44 0.08
138 INT157669 Regulation of CDK20 1 2 0.19 2.05 0.08
139 INT345437 Binding of Lox 1 1 0.07 0 0.07
140 INT345446 Negative_regulation of Binding of Lox 1 1 0.08 0 0.07
141 INT349283 Negative_regulation of Gene_expression of Nppb 1 1 0.05 0.3 0.06
142 INT246930 Negative_regulation of Transcription of Tlr2 1 1 0.36 0.92 0.04
143 INT280684 Transcription of Srebf1 1 11 0.50 2.38 0.03
144 INT201018 Transcription of PRKAB1 2 2 0.16 0.16 0.03
145 INT345436 Positive_regulation of Angptl4 1 1 0.37 0.21 0.03
146 INT280683 Gene_expression of Srebf1 2 12 0.44 6.31 0
147 INT280643 Negative_regulation of Gene_expression of Srebf1 4 4 0.32 1.01 0
148 INT280638 Positive_regulation of Transcription of Srebf1 1 4 0.37 1.18 0
149 INT229016 Gene_expression of Ppard 1 3 0.33 1.36 0
150 INT228573 Transcription of Gck 2 2 0.26 0.05 0
151 INT315043 Gene_expression of EAF2 1 2 0.11 0.43 0
152 INT246929 Positive_regulation of Localization of Tlr2 1 2 0.42 0.26 0
153 INT183060 Regulation of Transcription of INS 1 2 0.44 0.34 0
154 INT345450 Binding of Srebf1 2 1 0.03 0 0
155 INT327520 Binding of EAF2 1 1 0.06 0.42 0
156 INT349285 Localization of Serpina1a 1 1 0.21 1 0
157 INT246927 Negative_regulation of Binding of Tlr2 1 1 0.31 0 0
158 INT345447 Regulation of Gene_expression of Angptl4 1 1 0.33 0.09 0
159 INT345440 Negative_regulation of Abcg1 2 1 0.32 0.09 0
160 INT327521 Gene_expression of MIR9-2 3 1 0.58 0.99 0
161 INT349284 Transcription of Prtn3 1 1 0.45 0.65 0
162 INT345441 Positive_regulation of Transcription of Gck 1 1 0.18 0 0
163 INT345444 Positive_regulation of Transcription of Ppard 1 1 0.28 0 0
164 INT345451 Regulation of Gene_expression of Ech1 1 1 0.30 0.09 0
165 INT157670 Regulation of PSMC6 1 1 0.44 0.58 0
166 INT327517 Positive_regulation of Gene_expression of MIR92B 1 1 0.45 0.38 0
167 INT345448 Binding of Gck 1 1 0.13 0 0
168 INT345456 Positive_regulation of Transcription of PRKAB1 2 1 0.08 0 0
169 INT345449 Regulation of Transcription of Gck 1 1 0.16 0 0
170 INT345443 Positive_regulation of Ech1 1 1 0.45 0.1 0
171 INT327518 Gene_expression of MIR92A1 2 1 0.58 0.62 0
172 INT345439 Gene_expression of Ech1 1 1 0.51 0.09 0
173 INT327524 Positive_regulation of NDUFB3 1 1 0.40 0.37 0
174 INT345453 Binding of GCK 1 1 0.36 0 0
175 INT345454 Negative_regulation of Transcription of PRKAB1 1 1 0.06 0 0
176 INT345438 Positive_regulation of Gene_expression of Ech1 1 1 0.30 0.09 0
177 INT327523 Gene_expression of NDUFB3 1 1 0.45 0.38 0
178 INT345445 Transcription of Ppard 2 1 0.38 0 0
179 INT327519 Gene_expression of MIR92B 2 1 0.58 0.62 0
180 INT327522 Positive_regulation of COX7C 1 1 0.42 0.37 0
181 INT345442 Gene_expression of Angptl4 1 1 0.57 0.09 0
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