J:Clinical and Experimental Otorhinolaryngology

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 2 0.14 3.26 1.54
2 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 2 0.01 2.25 1.11
3 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 2 0.03 2.24 1.1
4 INT267630 Il1 Regulation of Gene_expression of IL8 1 1 0.00 0.44 0.71
5 INT267625 Binding of KNG1 and Klk1 2 1 0.21 2.23 0.61
6 INT171905 TNF Positive_regulation of Gene_expression of Il1 2 1 0.23 1.08 0.54
7 INT267585 TNF Regulation of IL6 2 1 0.16 2.44 0.37
8 INT267595 IL12A Positive_regulation of IFN1@ 1 1 0.03 0.69 0.36
9 INT267589 IL2 Positive_regulation of Gene_expression of IL12A 1 1 0.01 0.69 0.34
10 INT267628 IL4 Positive_regulation of IgG 1 1 0.00 1.42 0.27
11 INT267586 IL4 Positive_regulation of IGHE 1 1 0.00 1.42 0.27
12 INT267632 Il1 Positive_regulation of Gene_expression of PLA2G6 1 1 0.00 0.86 0.25
13 INT267624 Klk1 Positive_regulation of KNG1 1 1 0.05 0.52 0.25
14 INT267584 TNF Positive_regulation of Gene_expression of PLA2G6 1 1 0.08 0.87 0.25
15 INT267631 IRF6 Positive_regulation of Gene_expression of Il1 1 2 0.00 0.96 0.25
16 INT267596 KNG1 Positive_regulation of Gene_expression of PLA2G6 1 1 0.01 0.87 0.25
17 INT267591 CYSLTR1 Positive_regulation of Gene_expression of PLA2G6 1 1 0.00 0.87 0.25
18 INT267623 IL6 Positive_regulation of Crp 1 1 0.00 1.6 0.24
19 INT267629 PTAFR Positive_regulation of Localization of Il1 1 2 0.00 1.32 0.18
20 INT267660 CFTR Regulation of Gene_expression of P2RX2 1 1 0.25 0.51 0.18
21 INT267627 Il1 Positive_regulation of Gene_expression of TNF 1 1 0.02 0.45 0.17
22 INT267587 PTAFR Positive_regulation of Localization of PTPRC 1 3 0.00 2.04 0.09
23 INT267626 Il1 Positive_regulation of ICAM1 1 1 0.00 0.79 0.09
24 INT267618 Il1 Positive_regulation of Vcam1 1 1 0.00 0.81 0.09
25 INT267592 IL6 Positive_regulation of Localization of MUC1 1 1 0.00 1.24 0.07
26 INT267593 IL8 Positive_regulation of Localization of MUC1 1 1 0.00 1.06 0.06

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 17 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 13 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 3 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 5 1050 0.70 896.51 322.81
5 INT6852 Localization of TNF 5 883 0.81 705.95 270.84
6 INT10832 Gene_expression of IL8 16 1050 0.78 698.72 270
7 INT68684 Gene_expression of VEGFA 2 2371 0.78 1742.52 259.2
8 INT6481 Binding of TNF 3 624 0.48 510.2 214.82
9 INT6482 Positive_regulation of Gene_expression of TNF 6 659 0.70 569.88 210
10 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
11 INT10194 Positive_regulation of IL6 5 702 0.70 600.62 183.38
12 INT19472 Gene_expression of Il1 18 554 0.76 419.75 175.35
13 INT55879 Gene_expression of CCL2 6 421 0.78 240.74 166.02
14 INT5116 Gene_expression of IL2 6 670 0.78 291.13 146.69
15 INT9660 Regulation of TNF 2 363 0.62 312.94 139.99
16 INT12339 Localization of IL8 4 437 0.81 251.87 117.39
17 INT62124 Gene_expression of NOS1 1 444 0.78 218.08 114.85
18 INT48593 Positive_regulation of NOS1 2 420 0.68 226.15 114.71
19 INT11051 Positive_regulation of Gene_expression of IL6 1 415 0.69 319.21 109.3
20 INT60526 Gene_expression of IL10 5 449 0.78 292.71 107.84
21 INT10838 Positive_regulation of IL8 4 381 0.70 295.51 101.62
22 INT11587 Gene_expression of CSF2 1 645 0.78 544.38 93.89
23 INT48408 Gene_expression of ICAM1 3 494 0.78 340.08 88.6
24 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
25 INT56298 Gene_expression of IL4 3 306 0.78 182.18 72.92
26 INT12720 Positive_regulation of Il1 3 246 0.70 195.97 72.05
27 INT10837 Positive_regulation of Gene_expression of IL8 5 294 0.70 190.08 70.34
28 INT170332 Gene_expression of IFN1@ 1 477 0.75 275.21 69.65
29 INT4960 Positive_regulation of CSF2 1 285 0.70 256.73 65.73
30 INT1536 Negative_regulation of NA 1 244 0.55 52.67 59.79
31 INT48901 Negative_regulation of IL6 2 186 0.57 136.33 57.87
32 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
33 INT4509 Gene_expression of IGG 1 426 0.76 293.69 56.64
34 INT78899 Gene_expression of CCL5 3 155 0.77 84.02 55.09
35 INT19775 Localization of Il1 6 183 0.78 145.5 50.91
36 INT9210 Regulation of IL6 1 166 0.62 125.61 49.95
37 INT26500 Gene_expression of MMP2 1 201 0.78 110.57 46.9
38 INT81498 Positive_regulation of Gene_expression of CCL2 2 107 0.70 53.89 45.22
39 INT80124 Negative_regulation of VEGFA 1 450 0.58 311.19 44.53
40 INT25610 Positive_regulation of Gene_expression of Il1 1 136 0.67 104.43 43.86
41 INT61619 Gene_expression of IL12A 7 194 0.77 146.07 41.97
42 INT173693 Localization of Gopc 1 249 0.65 70.49 38.81
43 INT48222 Positive_regulation of Localization of IL8 1 123 0.59 78.04 37.2
44 INT9239 Regulation of Gene_expression of IL6 1 106 0.61 75.24 36.53
45 INT62827 Positive_regulation of ICAM1 2 184 0.70 180.95 36.28
46 INT79060 Gene_expression of NOS2 1 116 0.78 69.25 34.84
47 INT20380 Gene_expression of Il5 2 172 0.78 104.75 34.78
48 INT6105 Positive_regulation of IL2 1 133 0.69 82.76 34.67
49 INT10763 Localization of IL2 3 157 0.80 81.11 33.21
50 INT7538 Negative_regulation of IL2 1 95 0.57 47.31 31.7
51 INT17886 Negative_regulation of Il1 1 95 0.57 70.91 31.25
52 INT10506 Gene_expression of PTAFR 3 86 0.76 37.57 28.58
53 INT55737 Positive_regulation of MMP2 1 101 0.68 59.11 27.71
54 INT64499 Positive_regulation of IRF6 1 123 0.49 52.73 27.51
55 INT76095 Positive_regulation of ISYNA1 1 117 0.55 79.73 25.86
56 INT70048 Positive_regulation of Gene_expression of IL10 1 90 0.55 71.34 25.66
57 INT10836 Negative_regulation of IL8 1 95 0.59 52.59 24.71
58 INT79061 Positive_regulation of NOS2 1 92 0.65 58.89 23.96
59 INT49196 Gene_expression of SELE 1 105 0.78 107.29 22.92
60 INT69322 Negative_regulation of MAPK14 1 70 0.54 42.92 22.71
61 INT63340 Positive_regulation of Gene_expression of ICAM1 3 109 0.70 90.82 20.61
62 INT62042 Positive_regulation of Gene_expression of IL4 1 67 0.56 42.05 20.39
63 INT20129 Regulation of Il1 1 53 0.53 44.14 19.89
64 INT756 Gene_expression of C3 1 138 0.75 100.6 19.2
65 INT5160 Localization of PTAFR 6 61 0.80 42.6 19.16
66 INT56301 Positive_regulation of IL4 1 68 0.56 54.51 18.65
67 INT10833 Regulation of Gene_expression of IL8 1 68 0.62 38.74 18.46
68 INT23635 Positive_regulation of MMP12 1 31 0.59 28.19 17.95
69 INT2120 Gene_expression of CD79A 2 159 0.78 111.69 17.16
70 INT10000 Regulation of Gene_expression of IL2 1 56 0.45 15.33 16.2
71 INT52107 Transcription of IL8 2 63 0.72 41.66 16.06
72 INT170754 Localization of IFN1@ 2 121 0.78 66.78 15.6
73 INT26501 Positive_regulation of Gene_expression of MMP2 1 51 0.67 39 15.16
74 INT100938 Positive_regulation of Il13 1 47 0.69 42.11 14.36
75 INT25076 Negative_regulation of Gene_expression of Il1 1 41 0.52 30.58 13.85
76 INT6478 Negative_regulation of Binding of TNF 1 36 0.58 30.42 13.31
77 INT99586 Binding of IRF6 2 60 0.36 27.87 13.2
78 INT61624 Positive_regulation of Gene_expression of IL12A 1 50 0.56 33.07 13.07
79 INT70050 Negative_regulation of IL10 1 56 0.58 37.45 12.39
80 INT49142 Gene_expression of SELP 1 94 0.75 54.61 11.64
81 INT69029 Gene_expression of PTPRC 3 127 0.75 74.26 11.57
82 INT13303 Positive_regulation of PTAFR 1 40 0.69 16.27 11.56
83 INT150540 Binding of TLR2 1 50 0.45 35.86 10.43
84 INT105816 Gene_expression of P2RY2 1 53 0.78 16.47 9.67
85 INT62829 Positive_regulation of VCAM1 1 39 0.70 38.42 9.15
86 INT49802 Localization of MUC1 6 75 0.81 44.74 8.87
87 INT186273 Negative_regulation of Il13 1 33 0.46 22.88 8.65
88 INT22383 Binding of IL2 1 59 0.48 39.06 8.56
89 INT36798 Gene_expression of Mki67 4 178 0.77 132 8.24
90 INT4021 Positive_regulation of PLA2G1B 1 35 0.70 23.27 8.2
91 INT89048 Gene_expression of P2RX2 1 28 0.75 8.75 7.9
92 INT91667 Localization of IL12A 1 39 0.74 25.51 7.36
93 INT76253 Positive_regulation of P2RY2 1 29 0.70 13.99 7.33
94 INT138802 Gene_expression of CFTR 1 36 0.70 18.8 7.02
95 INT81443 Positive_regulation of Vcam1 1 29 0.63 28.4 6.35
96 INT75832 Positive_regulation of Positive_regulation of IL8 1 30 0.70 20.77 6.05
97 INT56299 Transcription of IL4 1 15 0.64 10.2 5.44
98 INT3165 Gene_expression of LYZ 2 25 0.65 16.72 5.16
99 INT151102 Positive_regulation of CFTR 3 22 0.61 15.27 5.12
100 INT1285 Localization of Mmp13 1 12 0.78 8.98 4.93
101 INT49805 Positive_regulation of MUC1 2 56 0.70 44.5 4.56
102 INT36855 Gene_expression of P2RY6 1 19 0.42 6.16 4.45
103 INT117920 Regulation of MAPK14 1 14 0.38 8.75 4.31
104 INT118615 Negative_regulation of IL4 1 20 0.41 13.79 3.49
105 INT63425 Positive_regulation of Gene_expression of SELP 1 23 0.67 15.34 3.48
106 INT53021 Positive_regulation of COL2A1 5 29 0.55 27.75 3.47
107 INT126560 Binding of P2RY2 1 12 0.44 6.43 3.4
108 INT26312 Positive_regulation of PLA2G6 1 26 0.70 7.41 3.2
109 INT124954 Gene_expression of Egfr 2 26 0.75 15.08 3.12
110 INT9884 Localization of CD79A 1 41 0.78 21.75 3.06
111 INT24895 Positive_regulation of LYZ 2 25 0.70 17.92 2.64
112 INT96693 Binding of COL2A1 1 45 0.46 37.11 2.61
113 INT230758 Positive_regulation of Gene_expression of PTPRC 1 11 0.49 6.04 2.45
114 INT173005 Transcription of MUC1 1 11 0.63 10.15 2.24
115 INT104263 Regulation of Positive_regulation of NOS1 1 5 0.28 3.15 2.15
116 INT145650 Localization of PLA2G6 1 15 0.76 8.87 2.06
117 INT135744 Positive_regulation of Id1 2 4 0.49 3.08 2.02
118 INT151101 Regulation of CFTR 1 4 0.62 3.69 1.89
119 INT169862 Regulation of NPC1 2 13 0.53 13.61 1.84
120 INT187095 Negative_regulation of Positive_regulation of Il1 1 8 0.14 6.17 1.82
121 INT124953 Negative_regulation of Gene_expression of Egfr 1 6 0.42 1.97 1.75
122 INT38266 Localization of PTPRC 6 30 0.68 17.05 1.68
123 INT78774 Gene_expression of PLA2G6 2 15 0.61 8.39 1.56
124 INT132163 Positive_regulation of Localization of MUC1 3 9 0.19 8.96 1.54
125 INT106359 Regulation of Plau 1 7 0.45 3.51 1.5
126 INT19432 Positive_regulation of Gene_expression of CD79A 2 14 0.45 13.49 1.49
127 INT18114 Gene_expression of NPC1 2 45 0.66 57.85 1.44
128 INT179169 Transcription of IL13 1 11 0.15 4.22 1.37
129 INT49804 Negative_regulation of Localization of MUC1 1 7 0.59 5.84 1.19
130 INT196675 Localization of CFTR 2 4 0.64 1.95 1.19
131 INT27387 Binding of Aecp 2 4 0.34 5.09 1
132 INT173021 Localization of MUC5AC 1 14 0.70 10.73 0.91
133 INT139840 Positive_regulation of Negative_regulation of MAPK14 1 2 0.21 1.55 0.67
134 INT179168 Regulation of Transcription of IL8 1 4 0.43 1.88 0.63
135 INT215183 Positive_regulation of MUC5AC 1 4 0.45 2.78 0.6
136 INT267615 Positive_regulation of Localization of PTPRC 2 3 0.01 3.41 0.46
137 INT267606 Protein_catabolism of CCL5 1 2 0.48 1.39 0.43
138 INT156997 Localization of NPC1 1 19 0.64 30 0.42
139 INT109913 Positive_regulation of MAP3K14 1 2 0.67 0.51 0.37
140 INT257576 Binding of P2RX2 1 4 0.20 1.29 0.36
141 INT202349 Positive_regulation of Map2k3 1 3 0.52 1.26 0.36
142 INT181304 Binding of CD48 1 3 0.08 2.43 0.34
143 INT267666 Regulation of Localization of CFTR 1 1 0.22 0.39 0.3
144 INT267667 Regulation of Clcn1 1 1 0.44 1.05 0.23
145 INT140912 Positive_regulation of Nexn 1 6 0.59 3.5 0.2
146 INT266832 Positive_regulation of Grxcr1 2 9 0.12 7.91 0.19
147 INT266822 Negative_regulation of Grxcr1 1 10 0.10 8.12 0.17
148 INT267616 Positive_regulation of Positive_regulation of MUC5AC 1 1 0.14 1.15 0.16
149 INT267610 Negative_regulation of Negative_regulation of MAPK14 1 1 0.03 1.08 0.15
150 INT237845 Localization of DCP2 1 2 0.43 1.16 0.13
151 INT234157 Regulation of Abr 1 2 0.20 0.42 0.11
152 INT261093 Positive_regulation of Gene_expression of PLA2G6 1 2 0.31 0.93 0.1
153 INT257450 Localization of MUC5B 1 2 0.62 1.14 0.09
154 INT184798 Positive_regulation of Localization of PLA2G6 1 2 0.16 2.41 0.05
155 INT219773 Gene_expression of Nexn 2 4 0.58 0.74 0.04
156 INT267670 Regulation of Nexn 4 4 0.39 3.95 0.04
157 INT173007 Transcription of MUC2 1 2 0.64 0.98 0.04
158 INT267608 Positive_regulation of MUC2 1 1 0.11 0.86 0.04
159 INT267609 Positive_regulation of Transcription of MUC2 1 1 0.11 0.86 0.04
160 INT267668 Positive_regulation of Gene_expression of Nexn 1 1 0.43 0.06 0.04
161 INT202348 Localization of Nexn 1 3 0.28 0.26 0.03
162 INT266818 Localization of Grxcr1 1 7 0.12 3.9 0
163 INT267671 Protein_catabolism of Nexn 4 5 0.85 3.15 0
164 INT267669 Positive_regulation of Protein_catabolism of Nexn 2 1 0.40 1.36 0
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