J:Crit Care

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT182124 Binding of IRF6 and TLR4 14 1 0.10 16.11 4.65
2 INT202959 Binding of BAG3 and MCRS1 1 6 0.11 7.46 3.14
3 INT1151 Binding of CCK and GAST 7 1 0.49 0.73 3.08
4 INT202965 Binding of STC2 and BAG3 1 6 0.02 7.86 2.96
5 INT202974 Binding of BAG3 and CPP 1 5 0.25 6.22 2.73
6 INT334136 Binding of IFNA1 and Acsm3 1 2 0.01 4.52 2.19
7 INT202963 Binding of STC2 and CPP 1 4 0.02 5.16 2.04
8 INT70043 IL6 Regulation of IL10 3 1 0.18 3.59 2.01
9 INT175986 Ros1 Positive_regulation of Gtf3a 2 1 0.01 4.75 1.71
10 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 1 0.52 6.58 1.68
11 INT182097 Binding of Il6 and Il1 4 1 0.07 4.67 1.55
12 INT334131 Acsm3 Positive_regulation of Mip 1 2 0.13 3.12 1.48
13 INT202958 Binding of STC2 and MCRS1 1 3 0.01 3.48 1.44
14 INT224404 Binding of GYPC and PYY 1 3 0.04 1.48 1.42
15 INT182096 Positive_regulation of Binding of Il6 and Il1 2 1 0.09 4.26 1.31
16 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 3 0.14 0.89 1.23
17 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 2 0.22 2.89 1.22
18 INT203016 CCK Positive_regulation of Localization of PYY 3 4 0.68 1.19 1.17
19 INT202960 Binding of MCRS1 and CPP 1 2 0.14 2.49 1.13
20 INT83616 Binding of IL6 and IL8 5 1 0.09 5.8 1.11
21 INT202968 Binding of MCRS1 and CAP1 1 2 0.03 2.46 1.08
22 INT250777 Binding of Cxcl10 and Cxcr1 1 2 0.14 3.1 1.04
23 INT182125 Binding of CD14 and TLR4 7 2 0.25 3.78 1.03
24 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 2 0.07 0.13 0.99
25 INT195668 Binding of F2 and THBD 7 3 0.08 5.67 0.98
26 INT334132 Acsm3 Positive_regulation of Gene_expression of Cxcl2 1 1 0.13 2.26 0.83
27 INT334130 Negative_regulation of Acsm3 Positive_regulation of Mip 1 1 0.12 1.48 0.81
28 INT81716 ITGAL Regulation of ITGB2 2 1 0.30 1.24 0.78
29 INT334134 Acsm3 Positive_regulation of Gene_expression of Mip 1 1 0.13 1.4 0.77
30 INT224403 Binding of CCK and GYPC 1 2 0.04 0.83 0.77
31 INT170127 Binding of ITGAL and PECAM1 2 1 0.01 2.71 0.75
32 INT195778 Binding of APC and PROCR 7 7 0.19 3.78 0.73
33 INT202967 MCRS1 Negative_regulation of CPP 2 1 0.14 2.2 0.73
34 INT334128 Acsm3 Positive_regulation of Sele 1 1 0.16 1.6 0.66
35 INT334133 Acsm3 Positive_regulation of Icam1 1 1 0.23 1.61 0.66
36 INT334127 Acsm3 Positive_regulation of Vcam1 1 1 0.24 1.61 0.66
37 INT244320 Tlr4 Positive_regulation of Aliq1 3 1 0.04 4.51 0.64
38 INT202962 CPP Negative_regulation of Positive_regulation of BAG3 1 1 0.26 1.34 0.61
39 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 2 0.31 1.73 0.6
40 INT202971 Binding of BAG3 and CAP1 1 1 0.04 1.26 0.59
41 INT202973 Binding of CAP1 and CPP 1 1 0.05 1.24 0.58
42 INT202970 Binding of STC2 and CAP1 1 1 0.00 1.25 0.58
43 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 1 0.16 1.64 0.57
44 INT202961 MCRS1 Negative_regulation of STC2 1 1 0.00 1.63 0.57
45 INT195666 Binding of PROC and THBD 2 1 0.40 2.42 0.56
46 INT195773 Binding of Cd74 and Mif 2 1 0.25 2.78 0.55
47 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 1 0.04 0 0.55
48 INT323611 Il1 Regulation of Hmgb1 1 2 0.17 2.36 0.55
49 INT182021 Binding of TNF and Il6 2 1 0.04 0.74 0.53
50 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 1 0.52 0 0.52
51 INT202957 CPP Negative_regulation of MCRS1 1 1 0.14 1.53 0.51
52 INT254125 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Il6 1 2 0.00 1.23 0.5
53 INT254119 Binding of Bcl2a1a and Tlr4 1 2 0.01 1.34 0.49
54 INT179237 Binding of SERPINA6 and POMC 1 2 0.03 1.15 0.49
55 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 1 0.02 1.22 0.47
56 INT202964 SGSM3 Positive_regulation of MCRS1 1 1 0.03 1.21 0.47
57 INT195769 MIF Regulation of Gene_expression of TP53I11 1 1 0.19 1.24 0.47
58 INT195774 Binding of MIF and Cd74 1 1 0.02 1.15 0.46
59 INT254120 Aliq1 Positive_regulation of Tbce 1 1 0.00 0.68 0.43
60 INT203017 Binding of CCK and PYY 1 1 0.38 0.62 0.43
61 INT316121 IL10 Regulation of Gene_expression of HLA-DRA 1 2 0.09 0.46 0.42
62 INT170157 NPPC Regulation of CSF2 1 2 0.12 1.36 0.42
63 INT182100 Positive_regulation of Binding of TNF and Il6 1 1 0.03 0.66 0.41
64 INT231842 Pcdh8 Positive_regulation of Akt1 1 4 0.00 1.59 0.4
65 INT175016 Binding of REN and S100A6 2 1 0.11 1.13 0.37
66 INT179207 KCNAB2 Regulation of Gene_expression of ATP1A4 1 1 0.00 1.25 0.37
67 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 1 0.06 0.77 0.36
68 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 1 0.07 0.77 0.36
69 INT250781 IRF6 Positive_regulation of AMIGO2 1 2 0.02 1.25 0.35
70 INT254123 Binding of Adora2b and Rai1 1 1 0.24 0.75 0.35
71 INT230786 Binding of AGT and ACE 4 1 0.15 2.53 0.34
72 INT175988 Ros1 Positive_regulation of Transcription of Gtf3a 1 1 0.01 1.56 0.34
73 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 1 0.03 0.86 0.34
74 INT175990 Ros1 Positive_regulation of Gene_expression of Gtf3a 1 1 0.01 1.56 0.34
75 INT262307 CAPNS1 Regulation of TAF9 1 1 0.04 1.23 0.33
76 INT195665 APC Negative_regulation of F8 1 1 0.04 1.53 0.32
77 INT195664 APC Negative_regulation of F5 1 1 0.08 1.51 0.31
78 INT195669 Binding of F2 and PROC 1 1 0.04 1.44 0.31
79 INT254122 Adora2a Regulation of Aliq1 1 1 0.01 0.85 0.3
80 INT191240 SAE1 Regulation of Localization of INS 1 1 0.08 1.15 0.3
81 INT250738 Binding of hs and Serpinc1 1 1 0.00 0.46 0.3
82 INT323654 Igfbp1 Negative_regulation of Binding of Igf1 and Igfbp1 1 1 0.21 1.14 0.29
83 INT323653 Binding of Igf1 and Igfbp1 1 1 0.20 1.14 0.29
84 INT170128 Binding of ITGAL and ITGB2 2 1 0.04 1.6 0.28
85 INT203015 CCK Regulation of Localization of PYY 1 1 0.24 0.61 0.28
86 INT220388 Gh1 Regulation of Cish 1 1 0.03 0.29 0.28
87 INT220380 Il6 Positive_regulation of Gene_expression of Igfbp1 1 1 0.09 0.29 0.27
88 INT220381 Il1a Positive_regulation of Gene_expression of Igfbp1 1 1 0.01 0.28 0.27
89 INT220390 TNF Positive_regulation of Gene_expression of Igfbp1 1 1 0.02 0.29 0.27
90 INT170258 Pecam1 Positive_regulation of Icam1 1 1 0.02 0.79 0.27
91 INT224406 INS Regulation of Localization of PYY 1 1 0.11 0.27 0.27
92 INT224405 INS Regulation of Localization of CCK 1 1 0.12 0.27 0.27
93 INT220317 Binding of CPB1 and PLEKHM1 1 2 0.00 0.93 0.26
94 INT180718 Binding of SARS and ACE2 3 3 0.12 7.76 0.25
95 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 1 0.23 0.2 0.25
96 INT254124 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Tbxa2r 1 1 0.00 0.62 0.25
97 INT179233 IRF6 Negative_regulation of Binding of GSR 1 1 0.03 0.83 0.25
98 INT323610 Tlr4 Positive_regulation of Hmgb1 1 1 0.25 0.2 0.25
99 INT179200 Binding of ICAM1 and IL8 1 1 0.03 1.02 0.25
100 INT177661 Binding of Trib3 and Myo1f 1 2 0.00 0.54 0.24
101 INT170158 NPPA Positive_regulation of Gene_expression of NPPB 1 1 0.13 0.91 0.23
102 INT179230 Binding of MAPK14 and GSR 1 1 0.03 0.5 0.23
103 INT179229 Binding of GSR and NR3C2 1 1 0.03 0.37 0.23
104 INT250783 APC Negative_regulation of SERPINE1 1 1 0.06 0.86 0.23
105 INT250782 APC Negative_regulation of F2 1 1 0.00 0.86 0.23
106 INT220383 Binding of Igf1 and Cotl1 1 1 0.03 0.37 0.22
107 INT316111 APC Negative_regulation of SAE1 1 1 0.04 1.21 0.22
108 INT195663 APC Negative_regulation of Gene_expression of IL6 1 1 0.16 1.18 0.22
109 INT231843 Tlr4 Positive_regulation of Nfkb1 1 1 0.01 1.23 0.22
110 INT250779 PROC Regulation of IRF6 Positive_regulation of AMIGO2 1 1 0.00 0.74 0.22
111 INT195705 Binding of SERPINC1 and SDC4 1 3 0.07 1.54 0.21
112 INT316110 Binding of APC and SAE1 1 1 0.03 1.16 0.2
113 INT254121 Binding of Tbce and Aliq1 1 1 0.00 0.69 0.2
114 INT258017 Binding of AGT and ANGPT2 3 1 0.11 2.35 0.19
115 INT323593 IRF6 Positive_regulation of PROCR 1 1 0.00 0.46 0.19
116 INT323592 IRF6 Positive_regulation of Positive_regulation of PROCR 1 1 0.00 0.46 0.19
117 INT323613 Il1 Regulation of Localization of Hmgb1 1 1 0.10 0.75 0.19
118 INT231836 Pcdh8 Regulation of Positive_regulation of Racgap1 1 1 0.00 0.58 0.18
119 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 1 0.00 0.58 0.18
120 INT191241 SST Regulation of SAE1 1 1 0.05 0.89 0.18
121 INT316129 Binding of HLA-DRA and IL10 1 2 0.12 3.1 0.17
122 INT334106 APC Negative_regulation of NFKB1 1 1 0.25 1.37 0.17
123 INT175991 Binding of VEGFA and Igf1 1 1 0.04 0.57 0.17
124 INT316132 IL10 Regulation of MARCH1 1 2 0.11 2.12 0.17
125 INT316122 IL10 Regulation of Gene_expression of MARCH1 1 2 0.19 2.12 0.17
126 INT220387 Gh1 Regulation of Localization of Igf1 1 1 0.05 0.3 0.17
127 INT334108 APC Negative_regulation of TNF 1 1 0.13 1.36 0.17
128 INT83514 SERPINC1 Negative_regulation of F2 2 1 0.16 0.62 0.16
129 INT316123 Binding of HLA-DRA and BCAR1 1 1 0.02 0.48 0.16
130 INT262257 Positive_regulation of NOS2 Positive_regulation of AMIGO2 1 1 0.02 0.99 0.16
131 INT316124 TLR2 Positive_regulation of Gene_expression of HLA-DRA 1 1 0.14 0.34 0.16
132 INT195708 SERPINC1 Negative_regulation of TNF 1 1 0.17 0.66 0.15
133 INT231844 Pcdh8 Negative_regulation of Positive_regulation of Akt1 1 1 0.00 0.63 0.15
134 INT231838 Pcdh8 Regulation of Cel 1 1 0.00 0.39 0.15
135 INT195770 Binding of CPB1 and MIF 1 1 0.01 0.47 0.15
136 INT250778 Binding of Socs3 and Atl1 1 1 0.01 0.6 0.14
137 INT231846 Pcdh8 Negative_regulation of Positive_regulation of Cel 1 1 0.00 0.91 0.14
138 INT220385 Binding of Igf1 and Gnrhr 1 2 0.05 0.99 0.14
139 INT220386 Binding of Gh1 and Igf1 1 2 0.07 0.99 0.14
140 INT220305 Binding of IL6 and IL10 1 1 0.00 0.51 0.14
141 INT254133 PLEC Regulation of MCRS1 1 1 0.03 0.33 0.13
142 INT262289 Regulation of Binding of PPIG and CC2D1A 1 1 0.01 1.52 0.13
143 INT316130 IRF6 Positive_regulation of Gene_expression of HLA-DRA 1 1 0.02 0.27 0.13
144 INT262290 Binding of PPIG and CC2D1A 1 1 0.01 1.52 0.13
145 INT220318 Binding of CPB1 and CCL2 1 1 0.01 0.46 0.13
146 INT184603 APC Negative_regulation of Gene_expression of TNF 1 1 0.09 0.97 0.13
147 INT316126 IL10 Regulation of CD14 1 1 0.12 0.22 0.13
148 INT179234 Binding of SERPINA6 and ELANE 1 1 0.01 0.22 0.12
149 INT203018 GHRH Positive_regulation of Localization of PYY 1 1 0.01 0.81 0.12
150 INT177675 Binding of CALM1 and Positive_regulation of Trib3 1 1 0.00 0.27 0.12
151 INT195662 Binding of PROC and KAT8 1 2 0.10 2.25 0.12
152 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 1 0.33 0.66 0.12
153 INT177674 CALM1 Positive_regulation of Trib3 1 1 0.00 0.27 0.12
154 INT184608 APC Regulation of Gene_expression of Nppa 1 1 0.06 1.11 0.12
155 INT180715 Binding of SARS and CLEC4M 2 1 0.12 2.92 0.11
156 INT175985 Igf1 Positive_regulation of Gene_expression of Serpina1c 1 1 0.14 0.55 0.11
157 INT195710 SERPINC1 Positive_regulation of F2 1 1 0.08 0.69 0.11
158 INT170159 Negative_regulation of NPPC Regulation of CSF2 1 1 0.20 0.33 0.11
159 INT220289 MARS Regulation of CEBPZ 1 1 0.02 0.93 0.11
160 INT195711 Negative_regulation of SERPINC1 Positive_regulation of F2 1 1 0.08 0.7 0.11
161 INT175987 Igf1 Positive_regulation of Serpina1c 1 1 0.13 0.54 0.11
162 INT262255 Binding of APC and F2R 1 2 0.05 3 0.1
163 INT177676 Binding of Trib3 and Myo1f Positive_regulation of Trib3 1 1 0.00 0.3 0.1
164 INT316131 IL10 Regulation of Regulation of HLA-DRA 1 1 0.09 1.31 0.09
165 INT250730 Hmgb1 Positive_regulation of Localization of TNF 1 1 0.08 0.92 0.09
166 INT238472 Binding of AVP and POR 1 1 0.02 0.85 0.09
167 INT250729 Crlf1 Positive_regulation of Localization of TNF 1 1 0.02 0.92 0.09
168 INT239839 IL18 Positive_regulation of TNF 1 1 0.11 1.08 0.09
169 INT311811 Binding of REN and RASGRP1 1 1 0.16 0.68 0.08
170 INT316125 IL10 Regulation of KRT20 1 1 0.00 1.06 0.08
171 INT195777 THBD Positive_regulation of PROC 1 1 0.00 1.26 0.08
172 INT250804 Binding of CCL4L1 and AP5M1 1 1 0.01 1.48 0.08
173 INT316127 IL10 Regulation of UBR1 1 1 0.00 1.06 0.08
174 INT323640 Vcam1 Positive_regulation of Gene_expression of Icam1 1 1 0.42 1.75 0.08
175 INT175984 Igf1 Regulation of Localization of Serpina1c 1 1 0.14 0.54 0.08
176 INT316112 Binding of S100B and SAE1 1 1 0.05 1.5 0.08
177 INT195709 Negative_regulation of Binding of SERPINC1 and SDC4 1 1 0.09 0.24 0.08
178 INT220288 MARS Regulation of AFM 1 1 0.06 1.14 0.08
179 INT250801 Binding of AP5M1 and MAPKAP1 1 1 0.00 1.48 0.08
180 INT231847 Binding of Akt1 and Sergef 1 2 0.00 0.23 0.07
181 INT231863 Binding of ARHGDIA and Akt1 1 2 0.02 0.23 0.07
182 INT175992 TNF Positive_regulation of Gene_expression of Cys1 1 1 0.01 0.34 0.07
183 INT231835 Binding of Akt1 and Grlf1 1 2 0.01 0.35 0.07
184 INT220290 Binding of AFM and MARS 1 1 0.05 1.09 0.07
185 INT172382 AGT Positive_regulation of Localization of EDN1 1 1 0.03 0.34 0.07
186 INT200536 Ca2 Positive_regulation of NOS1 1 1 0.03 0.74 0.07
187 INT191219 Edn1 Positive_regulation of Amigo2 1 2 0.06 1.26 0.07
188 INT172381 AVP Positive_regulation of Localization of EDN1 1 1 0.01 0.34 0.07
189 INT179232 Binding of CREM and GSR 1 1 0.00 0 0.06
190 INT191216 Binding of Edn1 and Cotl1 1 1 0.14 0.63 0.05
191 INT254161 Epo Positive_regulation of Nos2 1 1 0.37 0.54 0.05
192 INT222684 TEAD1 Negative_regulation of PROC 1 1 0.01 0.39 0.05
193 INT250802 Binding of IL6 and AP5M1 1 1 0.01 1.47 0.05
194 INT254162 Epo Positive_regulation of NOS1 1 1 0.01 0.53 0.05
195 INT231834 Trip12 Positive_regulation of Positive_regulation of Cel 1 1 0.00 0.75 0.05
196 INT316185 NUDT1 Regulation of ENO2 1 2 0.11 2.83 0.05
197 INT182098 Binding of IL8 and Il2 1 1 0.00 0 0.04
198 INT334107 Binding of APC and APCS 1 1 0.16 1.52 0.04
199 INT231806 ARHGDIA Negative_regulation of ARHGEF1 1 1 0.02 0.11 0.04
200 INT316109 TEAD1 Regulation of S100B 1 1 0.00 1.16 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 73 3152 0.78 2515.62 929.82
2 INT3439 Localization of Abat 1 1017 0.78 112.39 727.06
3 INT155 Positive_regulation of Prl 1 1233 0.70 317.93 457.82
4 INT443 Localization of POMC 3 1020 0.81 284.52 443.17
5 INT9238 Gene_expression of IL6 38 1575 0.78 1135.66 424.22
6 INT467 Gene_expression of POMC 8 1048 0.78 332.8 394.16
7 INT720 Positive_regulation of POMC 2 807 0.70 237.37 353.83
8 INT876 Localization of Gh1 1 843 0.80 67.75 340.82
9 INT5235 Negative_regulation of TNF 12 924 0.59 772.91 331.98
10 INT5059 Positive_regulation of TNF 22 1050 0.70 896.51 322.81
11 INT162 Regulation of Prl 1 794 0.62 165.01 322.24
12 INT9131 Positive_regulation of Prkcg 20 431 0.70 130.8 302.41
13 INT477 Localization of Avp 2 813 0.81 131.58 300.4
14 INT9158 Gene_expression of Tnf 13 722 0.78 522.01 277.68
15 INT2365 Positive_regulation of Cck 2 354 0.70 87.8 277.41
16 INT49750 Negative_regulation of CPOX 10 735 0.58 360.06 274.19
17 INT6852 Localization of TNF 16 883 0.81 705.95 270.84
18 INT10832 Gene_expression of IL8 19 1050 0.78 698.72 270
19 INT9659 Gene_expression of Il6 9 991 0.78 715.11 265.57
20 INT5972 Gene_expression of IL1B 7 948 0.78 510.91 263.97
21 INT68684 Gene_expression of VEGFA 34 2371 0.78 1742.52 259.2
22 INT16868 Gene_expression of Il6 21 807 0.78 499.48 256.57
23 INT1902 Gene_expression of Cck 2 348 0.78 70.33 241.92
24 INT1562 Localization of Crh 4 499 0.81 126.74 236.68
25 INT95787 Positive_regulation of Mapk1 5 568 0.70 226.51 220.94
26 INT1308 Localization of Pomc 1 457 0.81 66.83 217.5
27 INT6481 Binding of TNF 6 624 0.48 510.2 214.82
28 INT767 Localization of Gnrhr 1 565 0.80 106.68 214.57
29 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
30 INT6482 Positive_regulation of Gene_expression of TNF 19 659 0.70 569.88 210
31 INT48955 Gene_expression of Nos2 1 753 0.78 403.87 208.08
32 INT2391 Negative_regulation of PTGS1 2 501 0.59 207.62 205.6
33 INT9132 Negative_regulation of Prkcg 3 279 0.59 88.05 203.47
34 INT11313 Positive_regulation of Il6 6 526 0.70 331.27 201.59
35 INT6488 Gene_expression of Tnf 1 484 0.78 339.61 191.58
36 INT10194 Positive_regulation of IL6 14 702 0.70 600.62 183.38
37 INT19472 Gene_expression of Il1 17 554 0.76 419.75 175.35
38 INT15516 Gene_expression of Crp 30 711 0.77 615.33 173.09
39 INT438 Gene_expression of Crh 9 376 0.78 159.11 169.17
40 INT867 Gene_expression of IFNA1 2 930 0.78 594.85 168.03
41 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
42 INT55879 Gene_expression of CCL2 1 421 0.78 240.74 166.02
43 INT1114 Localization of Ins1 1 748 0.80 192.95 165.48
44 INT2366 Binding of Cck 5 192 0.48 30.64 163.46
45 INT66280 Gene_expression of Nos2 9 534 0.78 330.78 157.07
46 INT2910 Regulation of Abat 1 169 0.62 36.95 153.53
47 INT15515 Positive_regulation of Crp 25 700 0.70 604.24 150.15
48 INT13353 Positive_regulation of Tnf 4 332 0.70 248.75 148.1
49 INT2451 Positive_regulation of Avp 4 355 0.70 102.66 147.69
50 INT9852 Positive_regulation of Gpt 1 563 0.70 364.64 146.82
51 INT5116 Gene_expression of IL2 1 670 0.78 291.13 146.69
52 INT812 Localization of INS 22 1026 0.81 515.6 145.31
53 INT60694 Gene_expression of Il10 2 567 0.78 369.48 143.69
54 INT9660 Regulation of TNF 7 363 0.62 312.94 139.99
55 INT1273 Gene_expression of Avp 5 356 0.78 90.56 138.7
56 INT48895 Gene_expression of Il10 14 333 0.78 221.2 138.52
57 INT2867 Gene_expression of CALCA 1 247 0.78 78.78 138.47
58 INT48953 Positive_regulation of Nos2 2 486 0.70 239.85 131.87
59 INT5497 Positive_regulation of Crh 4 299 0.70 125.54 131.14
60 INT695 Binding of POMC 1 304 0.48 56.66 126.85
61 INT252 Localization of GH1 1 529 0.80 227.4 122.05
62 INT7533 Gene_expression of Tlr4 8 720 0.78 343.22 121.57
63 INT14151 Gene_expression of Casp3 3 311 0.78 140.26 120.68
64 INT8243 Positive_regulation of Il6 2 451 0.70 358.24 119.28
65 INT17612 Gene_expression of CRP 18 676 0.78 580.61 119.03
66 INT9235 Negative_regulation of Gene_expression of TNF 11 346 0.59 252.98 118.61
67 INT50674 Gene_expression of PTGS2 3 459 0.78 253.33 118.51
68 INT12339 Localization of IL8 5 437 0.81 251.87 117.39
69 INT4207 Regulation of Avp 1 267 0.62 63.72 115.33
70 INT62124 Gene_expression of NOS1 31 444 0.78 218.08 114.85
71 INT48593 Positive_regulation of NOS1 32 420 0.68 226.15 114.71
72 INT170025 Gene_expression of Fig4 1 588 0.67 183.27 113.32
73 INT11051 Positive_regulation of Gene_expression of IL6 3 415 0.69 319.21 109.3
74 INT27096 Positive_regulation of Nfkb1 2 325 0.70 195.11 109.06
75 INT47243 Gene_expression of Prkcg 2 195 0.78 58.05 108.44
76 INT60526 Gene_expression of IL10 49 449 0.78 292.71 107.84
77 INT3038 Gene_expression of INS 17 1583 0.78 1174.16 107.01
78 INT12082 Localization of IL6 3 365 0.81 241.78 105.78
79 INT18009 Positive_regulation of CRP 14 518 0.70 553.03 103.74
80 INT90091 Gene_expression of GOPC 5 967 0.67 366.22 103.6
81 INT10272 Gene_expression of Il1b 1 194 0.78 121.02 103.03
82 INT10838 Positive_regulation of IL8 7 381 0.70 295.51 101.62
83 INT82878 Gene_expression of Ccl2 1 201 0.78 164.95 101.35
84 INT5940 Negative_regulation of Avp 3 236 0.59 67.86 101.2
85 INT397 Localization of SST 2 232 0.81 58.05 101.19
86 INT11381 Positive_regulation of IL1B 2 330 0.70 209.31 100.9
87 INT874 Positive_regulation of Gh1 1 244 0.70 27.17 97.98
88 INT4860 Positive_regulation of CALCA 3 148 0.00 73.35 97.61
89 INT11587 Gene_expression of CSF2 3 645 0.78 544.38 93.89
90 INT203 Positive_regulation of Pomc 1 257 0.70 90.56 92.84
91 INT77435 Positive_regulation of Nos2 12 343 0.70 208.49 91.43
92 INT214 Localization of AVP 20 370 0.81 208.51 91.09
93 INT48767 Negative_regulation of NOS1 22 312 0.59 154.25 90.32
94 INT6585 Positive_regulation of Insrr 1 110 0.52 40.67 89.9
95 INT10166 Localization of Tnf 8 237 0.81 153.95 88.64
96 INT48408 Gene_expression of ICAM1 11 494 0.78 340.08 88.6
97 INT7180 Negative_regulation of Trib3 1 180 0.51 68.48 88.01
98 INT2149 Positive_regulation of Oxt 1 181 0.70 24.8 85.43
99 INT5617 Localization of Nppa 2 266 0.81 83.51 83.89
100 INT2520 Negative_regulation of Ca2 7 271 0.57 72.13 83.71
101 INT48406 Gene_expression of Icam1 21 277 0.78 238.28 81.71
102 INT68682 Positive_regulation of VEGFA 12 640 0.70 454.14 81.65
103 INT56291 Gene_expression of Ros1 3 503 0.63 274.12 81.5
104 INT99070 Gene_expression of Mapk14 1 147 0.78 103.99 79.59
105 INT2289 Gene_expression of PENK 1 203 0.78 55.62 79.49
106 INT2893 Localization of Oxt 1 219 0.80 28.96 79.43
107 INT2431 Positive_regulation of Mpo 4 275 0.70 211.99 78.47
108 INT19771 Positive_regulation of PAG1 1 69 0.61 75.61 76.88
109 INT3657 Gene_expression of Ins1 2 514 0.78 321.69 75.76
110 INT1724 Negative_regulation of ACE 4 437 0.59 315.64 74.48
111 INT12536 Localization of Prkcg 1 101 0.80 36.37 73.81
112 INT48244 Gene_expression of Il4 1 172 0.76 132.38 73.42
113 INT9236 Regulation of Gene_expression of TNF 6 204 0.62 162.66 72.99
114 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
115 INT12720 Positive_regulation of Il1 5 246 0.70 195.97 72.05
116 INT5969 Gene_expression of Il1a 4 221 0.75 96.31 71.38
117 INT14049 Positive_regulation of GRIN1 2 102 0.70 48.31 71.06
118 INT58400 Negative_regulation of Tnf 3 182 0.59 129.97 71
119 INT49995 Positive_regulation of Gene_expression of Tnf 5 187 0.70 125.07 70.54
120 INT10837 Positive_regulation of Gene_expression of IL8 3 294 0.70 190.08 70.34
121 INT79494 Positive_regulation of Gene_expression of VEGFA 5 577 0.70 442.94 69.73
122 INT39777 Regulation of Prkcg 1 90 0.62 31.52 68.17
123 INT19511 Localization of Il6 3 212 0.81 118.17 67.67
124 INT1603 Negative_regulation of Rtcd1 2 131 0.51 29.99 66.66
125 INT253 Regulation of PRL 1 184 0.62 47.27 65.79
126 INT4960 Positive_regulation of CSF2 4 285 0.70 256.73 65.73
127 INT13286 Gene_expression of Ca2 4 317 0.67 71.58 65.01
128 INT11807 Gene_expression of Il2 1 266 0.78 112 64.97
129 INT15514 Negative_regulation of Crp 2 275 0.59 194.6 64.86
130 INT11937 Localization of Il6 4 228 0.81 139.83 64.39
131 INT9657 Positive_regulation of Gene_expression of Il6 2 237 0.70 180.45 63.6
132 INT9664 Binding of LBP 2 127 0.48 94.9 63.42
133 INT1951 Positive_regulation of Tlr4 7 345 0.70 176.99 62.42
134 INT10706 Regulation of Il6 2 150 0.62 93.23 62.34
135 INT67981 Positive_regulation of CCL2 1 165 0.70 136.84 61.85
136 INT18981 Gene_expression of ABAT 3 78 0.68 38.35 61.36
137 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
138 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
139 INT103924 Positive_regulation of Akt1 17 359 0.69 158.94 60.34
140 INT546 Binding of ALB 11 311 0.48 85.98 60.14
141 INT1536 Negative_regulation of NA 1 244 0.55 52.67 59.79
142 INT5016 Negative_regulation of Crh 1 129 0.59 36.74 59.28
143 INT1307 Positive_regulation of Localization of Pomc 1 120 0.70 24.58 58.48
144 INT82055 Positive_regulation of Creb1 1 176 0.70 60.2 58.39
145 INT48901 Negative_regulation of IL6 8 186 0.57 136.33 57.87
146 INT9408 Positive_regulation of Crp 4 296 0.69 242.27 57.35
147 INT48891 Positive_regulation of Il10 3 143 0.70 101.42 56.72
148 INT5453 Regulation of Localization of POMC 1 114 0.62 20.56 56.34
149 INT1200 Negative_regulation of Ins1 4 274 0.58 155.17 56.14
150 INT52800 Negative_regulation of Gene_expression of Tnf 1 142 0.59 92.27 55.47
151 INT251 Regulation of INS 8 398 0.62 232.47 55.04
152 INT117223 Gene_expression of TLR4 2 348 0.78 206.18 54.42
153 INT1027 Gene_expression of Lbp 10 132 0.77 106.7 54.16
154 INT2276 Regulation of Ins1 1 234 0.61 103.78 54.05
155 INT49993 Positive_regulation of Gene_expression of Il6 3 149 0.70 88.07 53.78
156 INT96914 Phosphorylation of Mapk14 5 168 0.82 108.46 53.32
157 INT48952 Negative_regulation of Nos2 1 204 0.59 101.73 53.15
158 INT9234 Negative_regulation of Gene_expression of IL6 2 171 0.59 101.61 53.15
159 INT1032 Regulation of Ca2 4 202 0.52 54.91 53.03
160 INT62543 Gene_expression of Icam1 3 231 0.78 187.58 52.71
161 INT5623 Positive_regulation of Nppa 6 174 0.70 69.96 52.33
162 INT22112 Positive_regulation of Localization of TNF 3 164 0.70 115.66 52.18
163 INT72182 Gene_expression of Mcpt1 6 167 0.75 123.7 52.15
164 INT22546 Positive_regulation of Gene_expression of Casp3 1 97 0.70 47.89 51.92
165 INT249 Localization of GHRH 2 215 0.80 78.02 51.87
166 INT52264 Gene_expression of IK 1 180 0.77 90.87 51.87
167 INT1781 Negative_regulation of Gh1 2 127 0.59 16.94 51.77
168 INT83199 Gene_expression of Nos3 11 193 0.78 100.72 51.57
169 INT50405 Negative_regulation of CYP3A4 2 238 0.59 53.65 51.51
170 INT12345 Gene_expression of Il2 3 142 0.78 59.17 51.21
171 INT921 Regulation of GH1 1 172 0.60 52.88 51.04
172 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
173 INT1199 Positive_regulation of INS 16 579 0.70 399.64 50.43
174 INT9210 Regulation of IL6 9 166 0.62 125.61 49.95
175 INT2604 Positive_regulation of Got1 4 223 0.70 154.78 49.51
176 INT22454 Regulation of Crp 6 213 0.62 160.67 49.24
177 INT4345 Gene_expression of Gtf3a 3 157 0.67 80.75 48.47
178 INT17881 Gene_expression of LEP 1 278 0.78 221.61 48.31
179 INT1197 Negative_regulation of Localization of POMC 1 109 0.59 28.29 48.02
180 INT654 Localization of REN 4 250 0.81 75.12 47.86
181 INT106525 Phosphorylation of Akt1 11 436 0.82 183.81 47.82
182 INT2463 Localization of CCK 15 101 0.81 37.54 47.59
183 INT375 Positive_regulation of REN 11 293 0.70 152.46 47.55
184 INT374 Positive_regulation of Ldha 2 212 0.70 107.08 47.43
185 INT170646 Negative_regulation of Fig4 1 213 0.37 81.29 46.92
186 INT873 Gene_expression of Gh1 4 130 0.76 26.15 46.75
187 INT2406 Gene_expression of CCK 10 85 0.78 28.04 46.67
188 INT683 Positive_regulation of AVP 20 173 0.70 74.55 46.41
189 INT531 Gene_expression of GH1 1 376 0.75 193.45 46.24
190 INT1028 Positive_regulation of Lbp 3 102 0.69 67.86 46.05
191 INT5781 Gene_expression of Edn1 3 190 0.78 99.1 46
192 INT1322 Positive_regulation of Localization of INS 4 293 0.70 120.86 45.98
193 INT16364 Gene_expression of HLA-DRA 66 234 0.78 118.81 45.01
194 INT80124 Negative_regulation of VEGFA 12 450 0.58 311.19 44.53
195 INT2774 Binding of Crp 1 241 0.48 195.89 44.39
196 INT4216 Gene_expression of CD40LG 2 328 0.78 256.02 44.23
197 INT25610 Positive_regulation of Gene_expression of Il1 6 136 0.67 104.43 43.86
198 INT83953 Gene_expression of Cxcl2 10 140 0.75 113.07 43.65
199 INT73502 Positive_regulation of IL10 12 154 0.69 124.87 43.5
200 INT5307 Regulation of Tnf 4 87 0.62 78.71 43.4
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