J:Current Chemical Genomics

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 2 0.32 1.26 0.84
2 INT282505 Binding of ocd and Slc1a1 1 7 0.39 4.22 0.4
3 INT282501 Negative_regulation of Cyp19a1 Negative_regulation of Gene_expression of Aaiq4 1 1 0.01 0.6 0.27
4 INT347807 GLA Positive_regulation of Positive_regulation of A4GALT 1 2 0.05 1.57 0.13
5 INT347806 Binding of MOCS1 and SMAP2 1 1 0.00 0.48 0.12
6 INT311296 Akt1 Positive_regulation of Gene_expression of Clcn1 1 1 0.11 0 0.05
7 INT282503 Binding of ocd and Dlgap3 1 2 0.28 1.58 0.03
8 INT311298 Binding of DMPK and Mbnl1 1 1 0.43 0.54 0
9 INT311295 Gopc Positive_regulation of Gene_expression of Clcn1 1 1 0.07 0.29 0
10 INT282504 Binding of Grik2 and Grik3 1 1 0.27 0.61 0
11 INT282507 Binding of Grik3 and ocd 1 1 0.25 0.61 0
12 INT282502 Negative_regulation of Binding of ocd and Slc1a1 1 1 0.30 0.48 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT66280 Gene_expression of Nos2 18 534 0.78 330.78 157.07
2 INT120811 Gene_expression of Gopc 1 1174 0.59 428.49 150.55
3 INT77435 Positive_regulation of Nos2 3 343 0.70 208.49 91.43
4 INT1724 Negative_regulation of ACE 1 437 0.59 315.64 74.48
5 INT14049 Positive_regulation of GRIN1 1 102 0.70 48.31 71.06
6 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
7 INT1951 Positive_regulation of Tlr4 1 345 0.70 176.99 62.42
8 INT3361 Positive_regulation of Esr1 2 273 0.69 208.53 44.81
9 INT85943 Negative_regulation of Nos2 15 161 0.59 108.56 42.65
10 INT170054 Negative_regulation of Gopc 1 280 0.38 117.89 42.4
11 INT77434 Positive_regulation of Gene_expression of Nos2 5 151 0.69 96.76 38.94
12 INT16455 Gene_expression of Drd2 3 116 0.78 22.71 38.47
13 INT9694 Positive_regulation of Csf2 1 102 0.68 70.09 33.07
14 INT92837 Negative_regulation of Gene_expression of Nos2 8 116 0.59 59.67 31.82
15 INT101120 Gene_expression of Comt 4 63 0.77 34.75 26.13
16 INT172458 Regulation of Gopc 1 155 0.53 62.57 24.86
17 INT89854 Regulation of Nos2 7 49 0.61 42.58 24.1
18 INT5916 Positive_regulation of HTR1A 1 51 0.67 18.27 21.38
19 INT129987 Phosphorylation of Gria1 2 63 0.80 20.65 21.02
20 INT170444 Binding of Gopc 3 172 0.39 45.05 20.71
21 INT66281 Transcription of Nos2 8 81 0.71 39.49 20.37
22 INT73252 Positive_regulation of Mthfd1 1 124 0.59 59.48 18.35
23 INT59365 Gene_expression of HTR1A 2 41 0.75 16.31 16.57
24 INT77433 Regulation of Gene_expression of Nos2 1 49 0.62 35.07 16.33
25 INT74449 Positive_regulation of B4GALNT1 1 53 0.30 34.49 14.96
26 INT109031 Positive_regulation of Eif2ak3 1 44 0.69 21.11 14.72
27 INT65697 Positive_regulation of GRIN3B 2 23 0.69 12.52 13.78
28 INT97381 Negative_regulation of Positive_regulation of Nos2 1 34 0.59 16.66 11.6
29 INT145875 Gene_expression of Grm2 1 28 0.58 6.81 10.19
30 INT146343 Regulation of Slc6a3 1 17 0.60 7.33 8.27
31 INT116605 Binding of Nos2 1 28 0.37 16.88 8.18
32 INT69460 Positive_regulation of Grm2 2 12 0.49 6.54 8.18
33 INT112104 Binding of Grin2b 1 21 0.44 6.78 8.16
34 INT175526 Phosphorylation of Gopc 1 73 0.53 21.08 7.86
35 INT121496 Gene_expression of TERT 14 107 0.78 45.6 7.42
36 INT101121 Regulation of Comt 1 19 0.53 10.66 7.22
37 INT112459 Localization of Gba 1 12 0.80 1.45 6.4
38 INT57562 Gene_expression of GLA 3 52 0.77 24.62 6.14
39 INT65150 Gene_expression of Drb1 2 10 0.44 12.97 5.82
40 INT49632 Negative_regulation of NBL1 1 11 0.57 1.11 5.67
41 INT148968 Gene_expression of Gpbar1 2 29 0.56 11.9 5.66
42 INT186063 Phosphorylation of SOAT1 1 29 0.28 11.77 5.34
43 INT3550 Negative_regulation of GLA 2 52 0.59 33.93 5.26
44 INT116150 Positive_regulation of Ddit3 1 26 0.67 22.58 5.01
45 INT137336 Phosphorylation of Eif2ak3 2 14 0.79 4.72 4.78
46 INT20944 Gene_expression of Mcf2l 1 13 0.58 5.96 4.76
47 INT2848 Localization of ABCA1 1 23 0.70 10.64 4.73
48 INT118565 Gene_expression of Ddit3 1 35 0.75 23.62 4.32
49 INT85677 Positive_regulation of Gpbar1 1 24 0.68 8.41 4.09
50 INT172197 Positive_regulation of Gene_expression of Comt 1 12 0.69 7.61 4.06
51 INT120810 Binding of Dlg4 1 38 0.41 3.55 4.03
52 INT269961 Gene_expression of Hoxb8 14 3 0.69 14.28 3.91
53 INT172198 Protein_catabolism of Comt 1 7 0.88 2.78 3.6
54 INT206598 Regulation of Gene_expression of Comt 2 9 0.60 6 3.56
55 INT116235 Negative_regulation of Transcription of Nos2 3 23 0.58 7.91 3.14
56 INT110445 Phosphorylation of Gtf3a 1 15 0.09 5.58 3.07
57 INT198076 Gene_expression of Slc1a1 4 13 0.73 2.41 3.07
58 INT71946 Negative_regulation of Ass1 1 7 0.41 1.9 2.68
59 INT142724 Negative_regulation of A4GALT 2 11 0.53 8.23 2.61
60 INT97452 Positive_regulation of MOCS1 5 20 0.39 11.4 2.59
61 INT97453 Negative_regulation of MOCS1 2 25 0.04 13.4 2.4
62 INT73872 Positive_regulation of PDZK1IP1 2 3 0.19 0.44 2.27
63 INT69020 Gene_expression of Htr2c 2 9 0.74 6.09 2.22
64 INT134944 Gene_expression of MOCS1 2 37 0.06 10.76 2.17
65 INT55529 Negative_regulation of Gba 1 13 0.59 7.91 2.1
66 INT9429 Positive_regulation of Clcn1 2 18 0.58 10.03 2.07
67 INT68829 Binding of ELF3 1 14 0.47 7.96 2
68 INT141166 Positive_regulation of Gene_expression of Ddit3 1 15 0.56 10.32 1.92
69 INT167153 Gene_expression of A4GALT 1 10 0.49 10.45 1.71
70 INT218827 Negative_regulation of Phosphorylation of Gria1 2 6 0.36 3.61 1.67
71 INT91868 Transcription of B4GALNT1 2 5 0.10 1.5 1.66
72 INT121513 Positive_regulation of A4GALT 4 21 0.63 16.06 1.59
73 INT19467 Localization of Clcn1 1 7 0.66 2.84 1.59
74 INT77586 Positive_regulation of Gene_expression of HTR1A 1 6 0.46 3.54 1.51
75 INT65515 Binding of ocd 6 7 0.36 6.62 1.48
76 INT131125 Negative_regulation of Localization of Gba 1 2 0.08 0.24 1.48
77 INT16178 Gene_expression of Clcn1 10 20 0.69 8.67 1.46
78 INT129712 Positive_regulation of Gene_expression of TERT 4 12 0.70 7.3 1.44
79 INT47434 Gene_expression of Tnnt2 1 14 0.60 10.4 1.37
80 INT145874 Positive_regulation of Positive_regulation of Grm2 1 2 0.12 1.24 1.32
81 INT169173 Gene_expression of ocd 4 9 0.50 4.49 1.28
82 INT19466 Negative_regulation of Clcn1 1 6 0.52 3.39 1.22
83 INT287436 Positive_regulation of HTS 1 9 0.60 2.27 1.14
84 INT36179 Regulation of GLA 1 11 0.44 6.56 1.12
85 INT162471 Positive_regulation of ERN1 1 7 0.34 3.02 1.08
86 INT144465 Gene_expression of DMPK 4 9 0.69 5.01 0.94
87 INT128755 Protein_catabolism of Esr1 1 10 0.57 4.61 0.9
88 INT209387 Negative_regulation of Ugcg 2 9 0.25 7.61 0.9
89 INT116314 Gene_expression of Myod1 14 38 0.70 16.6 0.89
90 INT92836 Regulation of Transcription of Nos2 3 3 0.58 1.79 0.85
91 INT282479 Regulation of Protein_catabolism of Comt 1 2 0.45 1.17 0.85
92 INT57560 Positive_regulation of GLA 6 14 0.54 5.01 0.83
93 INT272511 Positive_regulation of DMPK 4 8 0.54 6.85 0.72
94 INT37012 Binding of Clcn1 1 11 0.33 4.83 0.7
95 INT191931 Negative_regulation of Binding of Gopc 1 13 0.29 4.83 0.68
96 INT164258 Positive_regulation of Gene_expression of GLA 1 6 0.47 0.55 0.65
97 INT141167 Positive_regulation of Atf6 1 3 0.41 1.41 0.64
98 INT195521 Regulation of Grm2 1 2 0.07 0.51 0.62
99 INT247751 Positive_regulation of Binding of Gopc 1 8 0.25 0.75 0.61
100 INT272475 Regulation of Mbnl1 3 15 0.61 5.39 0.56
101 INT255131 Gene_expression of Mbnl1 3 34 0.77 10.44 0.55
102 INT146784 Gene_expression of MYOD1 1 13 0.74 4.41 0.54
103 INT173744 Positive_regulation of Positive_regulation of Esr1 1 10 0.43 7.05 0.52
104 INT282488 Negative_regulation of ocd 3 1 0.43 2.38 0.49
105 INT137556 Negative_regulation of Cyp19a1 1 3 0.35 1.53 0.48
106 INT255113 Positive_regulation of Gene_expression of Mbnl1 1 15 0.69 3.28 0.47
107 INT291957 Negative_regulation of Mcpt2 1 1 0.03 0.23 0.47
108 INT186288 Negative_regulation of Binding of Nos2 1 3 0.35 1.08 0.42
109 INT311290 Positive_regulation of CELF1 5 1 0.40 1.52 0.41
110 INT291958 Negative_regulation of Phosphorylation of SOAT1 1 2 0.05 0.58 0.39
111 INT142723 Negative_regulation of Positive_regulation of A4GALT 1 4 0.38 1.65 0.34
112 INT211023 Positive_regulation of Gene_expression of Htr2c 1 2 0.45 2.03 0.33
113 INT172303 Localization of NCOR2 1 6 0.06 1.3 0.3
114 INT260581 Binding of DMPK 2 7 0.43 5.09 0.28
115 INT282487 Regulation of Negative_regulation of Cyp19a1 1 1 0.22 0.6 0.27
116 INT26678 Negative_regulation of Dmpk 1 11 0.47 3.45 0.26
117 INT282482 Positive_regulation of ocd 1 1 0.37 0.95 0.26
118 INT320171 Positive_regulation of Gene_expression of MOCS1 1 2 0.01 0.87 0.25
119 INT269960 Negative_regulation of Hoxb8 1 2 0.38 1.03 0.24
120 INT282483 Regulation of ocd 1 1 0.33 2.43 0.24
121 INT282486 Gene_expression of Aaiq4 1 1 0.01 0.6 0.24
122 INT282485 Positive_regulation of Gene_expression of Gpbar1 1 1 0.17 0.94 0.24
123 INT282473 Gene_expression of Dlgap3 5 1 0.71 3.11 0.23
124 INT117050 Binding of GLA 1 8 0.47 2.41 0.22
125 INT173211 Regulation of MOCS1 1 4 0.01 1.94 0.22
126 INT91865 Negative_regulation of Transcription of B4GALNT1 1 2 0.02 0.52 0.22
127 INT311292 Positive_regulation of Positive_regulation of DMPK 2 1 0.36 0.77 0.18
128 INT291955 Positive_regulation of Protein_catabolism of Esr1 1 1 0.06 0.14 0.17
129 INT192842 Binding of Hspa5 1 3 0.33 1.48 0.16
130 INT198075 Binding of Slc1a1 2 2 0.35 1.02 0.14
131 INT232584 Transcription of DMPK 4 5 0.47 3.41 0.13
132 INT347808 Binding of SMAP2 1 1 0.00 0.47 0.12
133 INT311275 Regulation of Gene_expression of Tnnt2 1 2 0.34 1.33 0.1
134 INT255128 Binding of Mbnl1 1 13 0.37 4.34 0.09
135 INT180484 Negative_regulation of SLITRK1 1 2 0.18 1.83 0.09
136 INT282477 Gene_expression of D1Sta7 1 1 0.01 0.67 0.09
137 INT291956 Positive_regulation of Negative_regulation of Nos2 1 1 0.41 0.54 0.08
138 INT272469 Negative_regulation of Gene_expression of Myod1 2 5 0.39 2.82 0.07
139 INT282484 Localization of Dlgap3 1 1 0.74 0.66 0.07
140 INT291959 Positive_regulation of Transcription of B4GALNT1 1 1 0.01 0.08 0.05
141 INT311283 Positive_regulation of Phosphorylation of CELF1 1 1 0.26 0 0.05
142 INT311288 Positive_regulation of Positive_regulation of CELF1 1 1 0.26 0 0.05
143 INT311293 Phosphorylation of CELF1 1 1 0.36 0 0.05
144 INT255102 Transcription of Dmpk 2 8 0.60 2.47 0.03
145 INT272509 Localization of DMPK 1 6 0.58 1.52 0.03
146 INT307030 Localization of LAMP1 1 4 0.42 0.57 0.03
147 INT256691 Binding of Xbp1 1 4 0.32 1.63 0.03
148 INT210071 Positive_regulation of Transcription of GLA 1 2 0.54 0.67 0.03
149 INT210062 Transcription of GLA 1 2 0.56 0.67 0.03
150 INT311289 Regulation of CELF1 3 1 0.15 1.78 0.03
151 INT291953 Positive_regulation of Binding of Xbp1 1 1 0.23 0.13 0.03
152 INT282478 Positive_regulation of Dlgap3 1 1 0.46 0.82 0.03
153 INT272462 Transcription of Clcn1 1 4 0.63 1.21 0
154 INT182486 Gene_expression of Tnnt3 1 3 0.50 2.22 0
155 INT272476 Negative_regulation of Transcription of Clcn1 1 3 0.43 1.05 0
156 INT301729 Positive_regulation of Gene_expression of Myod1 4 2 0.24 1.53 0
157 INT272461 Negative_regulation of Gene_expression of Clcn1 2 2 0.52 0.82 0
158 INT272504 Positive_regulation of Gene_expression of DMPK 1 2 0.39 0.54 0
159 INT311284 Negative_regulation of Gene_expression of DMPK 1 1 0.33 0.33 0
160 INT347809 Negative_regulation of Binding of A4GALT 1 1 0.05 0 0
161 INT282475 Negative_regulation of Dlgap3 1 1 0.39 0.7 0
162 INT347810 Binding of A4GALT 1 1 0.04 0 0
163 INT311279 Positive_regulation of Gene_expression of Clcn1 1 1 0.44 0.06 0
164 INT311276 Negative_regulation of Gene_expression of Mbnl1 1 1 0.37 0.32 0
165 INT311277 Regulation of Gene_expression of Clcn1 2 1 0.40 1 0
166 INT311294 Negative_regulation of Gene_expression of CELF1 1 1 0.24 0.32 0
167 INT311280 Positive_regulation of Transcription of Clcn1 1 1 0.44 0.24 0
168 INT311291 Regulation of MBNL1 1 1 0.02 0.69 0
169 INT291952 Phosphorylation of Nkrf 2 1 0.01 0.31 0
170 INT311285 Positive_regulation of Gene_expression of TRNAE1 1 1 0.49 0.05 0
171 INT282476 Binding of Grik2 1 1 0.31 0.61 0
172 INT311286 Gene_expression of CELF1 2 1 0.38 0.48 0
173 INT282480 Binding of Grik3 1 1 0.39 0.61 0
174 INT311278 Regulation of Gene_expression of Tnnt3 1 1 0.34 0.44 0
175 INT311287 Gene_expression of TRNAE1 1 1 0.65 0.05 0
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