J:Dermatology Research and Practice

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT320765 Dsg2 Positive_regulation of Akt1 1 1 0.48 0.74 0.13
2 INT320770 Dsg2 Positive_regulation of Stat3 1 1 0.28 0.74 0.13
3 INT320768 Spp1 Regulation of Protein_catabolism of Dsg1a 1 1 0.08 0.77 0.11
4 INT320766 Spp1 Negative_regulation of Dsg1a 1 1 0.11 1.05 0
5 INT320767 Atp11c Negative_regulation of Dsg1a 1 1 0.05 1.71 0
6 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 1 0.16 0.88 0
7 INT320771 Atp11c Regulation of Localization of Dsg1a 1 1 0.03 1.46 0
8 INT320712 Binding of NRAS and PIK3CD 1 2 0.21 1.66 0
9 INT320713 NRAS Positive_regulation of AKT1 1 1 0.37 0.84 0
10 INT320715 NRAS Positive_regulation of PIK3CD 1 2 0.27 1.66 0
11 INT320769 Atp11c Regulation of Dsg1a 1 4 0.05 5.87 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT96914 Phosphorylation of Mapk14 1 168 0.82 108.46 53.32
2 INT110023 Negative_regulation of Mapk14 1 127 0.59 84.27 45.42
3 INT65960 Gene_expression of BCL2 1 352 0.78 312.03 30.73
4 INT110427 Gene_expression of Spp1 3 199 0.78 176.11 23.31
5 INT86187 Positive_regulation of AKT1 2 199 0.69 122.13 19.44
6 INT96911 Positive_regulation of Phosphorylation of Mapk14 2 46 0.70 43.03 15.15
7 INT78472 Gene_expression of CDKN2A 1 223 0.78 173.76 13.61
8 INT89395 Negative_regulation of AKT1 1 127 0.58 70.27 12.54
9 INT117113 Regulation of Mapk14 1 28 0.45 16.71 11.99
10 INT65959 Positive_regulation of Gene_expression of BCL2 1 75 0.70 77.3 8.27
11 INT53487 Gene_expression of TSC1 1 81 0.58 77.71 7.94
12 INT122901 Positive_regulation of Spp1 1 67 0.67 58.03 7.49
13 INT75501 Gene_expression of CCND1 3 90 0.76 60.86 5.93
14 INT89794 Positive_regulation of CDKN2A 1 58 0.67 50.18 5.38
15 INT105336 Regulation of AKT1 1 52 0.56 32.53 4.89
16 INT136791 Negative_regulation of Spp1 1 24 0.59 23.6 3.33
17 INT94164 Phosphorylation of RB1 1 83 0.80 48.84 3.21
18 INT55002 Gene_expression of ASAP1 1 46 0.64 22.8 3.2
19 INT73263 Negative_regulation of MYC 1 20 0.57 12.86 2.95
20 INT92141 Negative_regulation of CDKN2A 1 53 0.57 44.23 2.48
21 INT27114 Gene_expression of Atp11c 10 20 0.42 22.22 2.37
22 INT176510 Binding of Spp1 2 21 0.42 22.1 2
23 INT176516 Localization of Spp1 2 28 0.76 19.39 1.9
24 INT56925 Negative_regulation of TSC1 1 54 0.52 63.39 1.87
25 INT65684 Gene_expression of MDM2 2 30 0.62 24.94 1.55
26 INT157765 Negative_regulation of CDH1 1 32 0.53 35.72 1.15
27 INT198870 Binding of Gpx3 1 5 0.01 2.47 0.81
28 INT176528 Regulation of Spp1 1 9 0.45 9.05 0.77
29 INT119834 Phosphorylation of PTEN 1 12 0.79 6.78 0.75
30 INT132521 Gene_expression of BRAF 1 14 0.65 13.59 0.73
31 INT115784 Gene_expression of GNAQ 3 5 0.65 4.48 0.7
32 INT299338 Negative_regulation of Regulation of AKT1 1 2 0.31 2.32 0.68
33 INT20213 Binding of Atp11c 1 6 0.08 2.11 0.66
34 INT44478 Negative_regulation of PTEN 3 32 0.57 27.45 0.63
35 INT75498 Positive_regulation of Gene_expression of CCND1 3 21 0.68 19.4 0.51
36 INT175423 Positive_regulation of TSC1 1 25 0.36 21.81 0.45
37 INT234930 Binding of Dsg3 4 25 0.48 20.73 0.44
38 INT234876 Negative_regulation of Dsg3 11 29 0.59 25.47 0.4
39 INT289704 Protein_catabolism of Spp1 2 5 0.27 2.42 0.39
40 INT203636 Positive_regulation of CD2AP 1 4 0.13 1.27 0.28
41 INT221860 Negative_regulation of Jup 2 9 0.15 6.82 0.26
42 INT180415 Regulation of Rhoa 1 7 0.53 3.92 0.22
43 INT234933 Gene_expression of Dsg2 29 3 0.71 38.52 0.2
44 INT260849 Gene_expression of NBN 3 9 0.67 7.11 0.16
45 INT71437 Positive_regulation of Gene_expression of Atp11c 2 2 0.27 5.63 0.16
46 INT234857 Gene_expression of Dsg3 12 42 0.78 27.75 0.14
47 INT200671 Gene_expression of AKT3 1 4 0.69 1.88 0.13
48 INT163232 Gene_expression of Invs 1 2 0.75 1.77 0.13
49 INT320751 Negative_regulation of Dsg1a 6 1 0.59 7.3 0.12
50 INT234888 Binding of Dsg2 3 9 0.34 11.73 0.11
51 INT320761 Protein_catabolism of Dsg1a 6 1 1.00 6.9 0.11
52 INT234919 Negative_regulation of Dsg2 1 5 0.39 6.76 0.04
53 INT186460 Transcription of ASAP1 1 5 0.56 3.02 0.03
54 INT320723 Negative_regulation of Gene_expression of BRAF 1 2 0.38 1 0.03
55 INT206135 Positive_regulation of NRAS 2 2 0.62 2.23 0.03
56 INT304052 Binding of MSI1 1 8 0.05 12.19 0
57 INT234862 Gene_expression of Dsc2 3 8 0.70 3.29 0
58 INT98696 Regulation of Dsg3 1 4 0.45 5.45 0
59 INT313785 Gene_expression of Dsg1a 19 3 0.78 18.92 0
60 INT320732 Binding of PIK3CD 2 3 0.20 1.66 0
61 INT234923 Binding of Dsc2 2 2 0.34 1.8 0
62 INT271963 Phosphorylation of TSC1 1 2 0.31 2.02 0
63 INT98697 Regulation of Dsg1a 4 2 0.45 7.33 0
64 INT313792 Regulation of Hspb2 1 1 0.08 1.47 0
65 INT320753 Positive_regulation of Localization of Dsg1a 1 1 0.50 0.76 0
66 INT320758 Localization of Dsg1a 4 1 0.80 4.07 0
67 INT320742 Gene_expression of Dsg4 3 1 0.31 1.3 0
68 INT320759 Positive_regulation of Dsg1a 3 1 0.70 2.17 0
69 INT320726 Negative_regulation of Gene_expression of TBX3 1 1 0.16 0.66 0
70 INT313790 Negative_regulation of Dsc3 5 1 0.58 3.15 0
71 INT320746 Binding of Dsg1a 5 1 0.48 6.43 0
72 INT313786 Negative_regulation of Gene_expression of Dsc3 1 1 0.58 0.81 0
73 INT320763 Regulation of Gene_expression of Dsg2 3 1 0.41 4.84 0
74 INT320736 Binding of NRAS 1 1 0.32 0.82 0
75 INT320730 Positive_regulation of Gene_expression of NBN 2 1 0.60 1.84 0
76 INT320733 Negative_regulation of TBX3 1 1 0.16 0.66 0
77 INT320756 Localization of Atp11c 1 1 0.07 0.78 0
78 INT320743 Negative_regulation of Gene_expression of Dsg2 3 1 0.39 3.95 0
79 INT320727 Positive_regulation of TBX3 1 1 0.19 0.84 0
80 INT320755 Positive_regulation of Negative_regulation of Dsg1a 1 1 0.50 1.23 0
81 INT313789 Gene_expression of Dsc3 7 1 0.76 3 0
82 INT320731 Positive_regulation of RPP14 1 1 0.34 1.04 0
83 INT320762 Binding of Gm4736 1 1 0.11 1.2 0
84 INT320728 Gene_expression of APITD1 1 1 0.60 1.44 0
85 INT313787 Binding of Dsc1 1 1 0.22 0.24 0
86 INT320752 Localization of Dsg2 1 1 0.73 0.78 0
87 INT313783 Transcription of Dsc2 2 1 0.63 0.42 0
88 INT320748 Positive_regulation of Protein_catabolism of Dsg1a 1 1 0.50 1.55 0
89 INT320718 Positive_regulation of Positive_regulation of CD2AP 1 1 0.08 0.55 0
90 INT320720 Gene_expression of TBX3 3 1 0.29 3.53 0
91 INT320745 Negative_regulation of Gene_expression of Dsg1a 2 1 0.43 1.87 0
92 INT320719 Negative_regulation of RPP14 1 1 0.30 1.04 0
93 INT320750 Regulation of Gene_expression of Dsg1a 2 1 0.45 3.44 0
94 INT320740 Positive_regulation of Dsg2 1 1 0.40 1.09 0
95 INT320744 Regulation of Ivl 1 1 0.01 1.64 0
96 INT320729 Positive_regulation of Negative_regulation of RPP14 1 1 0.32 1.04 0
97 INT320747 Negative_regulation of Binding of Dsg1a 1 1 0.43 1.36 0
98 INT313784 Positive_regulation of Negative_regulation of Dsg3 1 1 0.47 1.3 0
99 INT320721 Protein_catabolism of NRAS 1 1 0.59 0.89 0
100 INT313791 Gene_expression of Dsc1 1 1 0.36 0.25 0
101 INT320739 Positive_regulation of Gene_expression of Dsg2 6 1 0.63 8.03 0
102 INT320734 Positive_regulation of Gene_expression of AKT3 1 1 0.62 0.65 0
103 INT320749 Regulation of Localization of Dsg1a 2 1 0.45 2.53 0
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