J:Dig Dis Sci

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT338691 Binding of Trpv1 and Aff3 1 3 0.24 1.21 1.88
2 INT338695 CAP1 Regulation of Trpv1 1 1 0.01 0.14 0.85
3 INT338693 Aff3 Positive_regulation of Localization of CAP1 1 1 0.01 0.39 0.69
4 INT338690 Aff3 Positive_regulation of Trpv1 1 1 0.39 0.4 0.67
5 INT338692 CAP1 Negative_regulation of Positive_regulation of Aff3 1 1 0.01 0.2 0.44
6 INT210263 Mtx1 Regulation of Gene_expression of LYZ 1 1 0.00 0.33 0.32
7 INT296372 Binding of IDUA and ACD 1 1 0.03 2.72 0.23
8 INT210258 Wnt2 Regulation of Gene_expression of Tff3 1 1 0.03 0 0.05
9 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 1 0.64 0 0.05
10 INT210260 Sox9 Negative_regulation of Cdx2 1 1 0.20 0 0.03
11 INT338694 Aff3 Positive_regulation of PGC 1 1 0.00 0.33 0
12 INT271767 GOPC Regulation of MUC1 1 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 1 2008 0.81 518.3 1408.65
2 INT58061 Gene_expression of Trpv1 4 1117 0.78 451.54 637.59
3 INT64202 Positive_regulation of Trpv1 3 643 0.70 249.66 397.42
4 INT18357 Gene_expression of TRPV1 3 825 0.78 307.11 382.81
5 INT16868 Gene_expression of Il6 4 807 0.78 499.48 256.57
6 INT11313 Positive_regulation of Il6 5 526 0.70 331.27 201.59
7 INT120811 Gene_expression of Gopc 3 1174 0.59 428.49 150.55
8 INT60126 Regulation of Trpv1 2 186 0.62 85.53 133.4
9 INT65600 Positive_regulation of Casp3 1 376 0.70 198.44 128.03
10 INT170025 Gene_expression of Fig4 1 588 0.67 183.27 113.32
11 INT90091 Gene_expression of GOPC 2 967 0.67 366.22 103.6
12 INT89054 Positive_regulation of Gene_expression of Trpv1 2 156 0.70 90.78 102.03
13 INT397 Localization of SST 15 232 0.81 58.05 101.19
14 INT38731 Localization of Trpv1 1 138 0.81 52.73 90.49
15 INT4830 Binding of Trpv1 2 158 0.48 45.11 84.2
16 INT5617 Localization of Nppa 2 266 0.81 83.51 83.89
17 INT2431 Positive_regulation of Mpo 9 275 0.70 211.99 78.47
18 INT171145 Positive_regulation of Fig4 4 274 0.59 93.55 69.81
19 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
20 INT169926 Positive_regulation of Gopc 1 416 0.46 157.8 58.67
21 INT31116 Gene_expression of Casp3 7 192 0.78 78.21 57.43
22 INT647 Gene_expression of SGCG 7 211 0.75 78.46 55.82
23 INT77855 Gene_expression of Pain1 1 55 0.75 67.42 54.1
24 INT52264 Gene_expression of IK 1 180 0.77 90.87 51.87
25 INT170646 Negative_regulation of Fig4 1 213 0.37 81.29 46.92
26 INT9383 Localization of TRPV1 1 98 0.81 33.23 46.24
27 INT5781 Gene_expression of Edn1 2 190 0.78 99.1 46
28 INT2429 Negative_regulation of Mpo 3 128 0.59 93.76 39.57
29 INT173693 Localization of Gopc 2 249 0.65 70.49 38.81
30 INT68975 Gene_expression of Mmp9 1 111 0.78 79.57 38.55
31 INT58062 Negative_regulation of Gene_expression of Trpv1 1 66 0.59 22.34 38.02
32 INT100733 Positive_regulation of F2RL1 2 62 0.70 59.14 35.22
33 INT145594 Gene_expression of Mtx1 1 64 0.57 35.33 30.35
34 INT5650 Gene_expression of Mpo 2 117 0.77 80.27 26.42
35 INT172458 Regulation of Gopc 1 155 0.53 62.57 24.86
36 INT22708 Gene_expression of MUC1 6 297 0.78 232.71 24.19
37 INT24569 Negative_regulation of Pain1 3 26 0.41 21.82 21.08
38 INT96511 Negative_regulation of Positive_regulation of Trpv1 1 35 0.59 10.95 19.79
39 INT78694 Positive_regulation of Gene_expression of Casp3 1 46 0.66 18.64 19.62
40 INT712 Positive_regulation of LDHA 3 160 0.70 175.25 19.11
41 INT56749 Gene_expression of PCNA 11 219 0.77 111.25 18.42
42 INT667 Negative_regulation of Hrh2 1 38 0.58 18.11 18.01
43 INT38056 Localization of Crp 2 71 0.78 53.14 17.03
44 INT170051 Positive_regulation of Gene_expression of Gopc 1 150 0.43 56.75 16.93
45 INT170033 Positive_regulation of Gene_expression of Fig4 1 59 0.43 20.99 16.69
46 INT20622 Gene_expression of LDHA 2 107 0.76 77.97 16.3
47 INT2243 Localization of GAST 11 67 0.81 34.54 16.19
48 INT2243 Localization of GAST 3 67 0.81 34.54 16.19
49 INT170855 Negative_regulation of GOPC 2 188 0.38 70.92 15.41
50 INT125384 Positive_regulation of Pain1 2 23 0.49 17.1 14.83
51 INT36336 Gene_expression of Tgfb1 7 41 0.77 21.82 14.53
52 INT7413 Positive_regulation of Localization of SST 3 37 0.69 5.64 13.94
53 INT6365 Localization of Edn1 1 56 0.81 18.84 13.83
54 INT18012 Gene_expression of EPO 1 169 0.78 108.36 13.75
55 INT8548 Gene_expression of HP 1 86 0.77 47.62 11.94
56 INT5649 Negative_regulation of Positive_regulation of Mpo 2 31 0.59 26.62 11.92
57 INT50933 Transcription of Il6 1 38 0.72 24.31 11.58
58 INT68976 Positive_regulation of Gene_expression of Mmp9 1 34 0.42 28.21 11.28
59 INT13240 Gene_expression of TF 1 94 0.76 57.81 10.99
60 INT9385 Localization of LDHA 1 74 0.81 31.67 10.5
61 INT137400 Regulation of Mtx1 2 16 0.52 9.19 9.45
62 INT49802 Localization of MUC1 6 75 0.81 44.74 8.87
63 INT26795 Gene_expression of Mtpn 1 44 0.62 27.66 8.62
64 INT197 Gene_expression of Hrh2 1 24 0.63 12.35 8.37
65 INT113987 Localization of IK 1 29 0.23 16.73 8.25
66 INT150422 Positive_regulation of Aes 1 24 0.43 15.63 8
67 INT111607 Gene_expression of CDH1 1 103 0.75 90.45 7.77
68 INT15872 Positive_regulation of EPO 2 74 0.70 45.35 6.67
69 INT7205 Positive_regulation of HBG1 2 65 0.69 40.35 6.37
70 INT118516 Positive_regulation of Positive_regulation of F2RL1 1 7 0.49 4.63 6.33
71 INT329292 Gene_expression of Aff3 9 3 0.54 3.24 5.87
72 INT3165 Gene_expression of LYZ 1 25 0.65 16.72 5.16
73 INT18011 Positive_regulation of HP 1 60 0.50 31.88 4.75
74 INT127698 Localization of AIFM1 5 15 0.79 13.45 4.74
75 INT124375 Gene_expression of Wnt2 2 67 0.56 38.03 4.67
76 INT1539 Positive_regulation of MSMB 1 22 0.69 9.42 4.62
77 INT76884 Positive_regulation of Cp 1 22 0.69 12.84 4.6
78 INT49805 Positive_regulation of MUC1 10 56 0.70 44.5 4.56
79 INT9758 Positive_regulation of Slc4a4 1 13 0.40 0.26 4.37
80 INT338681 Positive_regulation of Aff3 6 1 0.56 1.22 3.91
81 INT76869 Localization of PAEP 1 15 0.73 6.57 3.36
82 INT117476 Negative_regulation of Gene_expression of Mpo 1 10 0.43 8.25 3.33
83 INT69216 Positive_regulation of Tgfb1 1 14 0.49 5.84 3.29
84 INT18462 Positive_regulation of Pgc 7 29 0.57 22.55 3.24
85 INT85149 Negative_regulation of Gene_expression of Tgfb1 2 11 0.42 4.73 3.19
86 INT76403 Gene_expression of Cnp 1 16 0.70 8.36 3.07
87 INT36404 Regulation of Localization of GAST 3 9 0.62 1.38 3.03
88 INT45503 Binding of EPO 2 42 0.48 24.85 2.88
89 INT9188 Localization of HBG1 2 12 0.75 8.14 2.24
90 INT101572 Negative_regulation of Gene_expression of PCNA 1 24 0.53 13.87 2.21
91 INT9254 Negative_regulation of LDHA 4 23 0.43 13.3 2.2
92 INT23667 Gene_expression of Hgfac 1 10 0.03 6.74 2.19
93 INT6635 Negative_regulation of Cnp 1 9 0.57 5.85 2.15
94 INT14 Regulation of LDHA 1 22 0.57 15.26 2.14
95 INT69702 Positive_regulation of PMAIP1 1 7 0.35 8.81 1.98
96 INT245945 Localization of CAP1 1 4 0.69 1.63 1.95
97 INT127695 Positive_regulation of Localization of AIFM1 2 5 0.64 4.29 1.87
98 INT329296 Binding of Aff3 2 3 0.39 1.72 1.77
99 INT120088 Gene_expression of Bmp4 22 37 0.73 13.89 1.73
100 INT329293 Negative_regulation of Aff3 3 2 0.34 1.22 1.69
101 INT102532 Protein_catabolism of Casp3 1 24 0.64 16.78 1.64
102 INT132163 Positive_regulation of Localization of MUC1 2 9 0.19 8.96 1.54
103 INT27762 Positive_regulation of Gene_expression of EPO 1 18 0.70 17.67 1.45
104 INT35654 Gene_expression of Pgc 1 6 0.65 7.97 1.44
105 INT38990 Negative_regulation of IDUA 1 12 0.59 5.04 1.33
106 INT38989 Gene_expression of IDUA 5 22 0.78 16.99 1.26
107 INT132453 Binding of TF 3 31 0.36 12.98 1.22
108 INT157765 Negative_regulation of CDH1 1 32 0.53 35.72 1.15
109 INT111605 Positive_regulation of CDH1 1 12 0.50 7.95 1.15
110 INT338685 Regulation of Aff3 2 1 0.36 0.69 1.07
111 INT124374 Binding of Wnt2 1 21 0.31 10.16 0.99
112 INT123852 Negative_regulation of Positive_regulation of Tgfb1 1 3 0.28 1.69 0.94
113 INT296385 Binding of IDUA 11 12 0.39 20.73 0.93
114 INT153145 Negative_regulation of Localization of AIFM1 1 2 0.50 1.79 0.93
115 INT24815 Binding of LDHA 1 9 0.36 6.73 0.89
116 INT142122 Regulation of Gene_expression of Bmp4 2 5 0.43 2.69 0.86
117 INT8159 Binding of ELL 1 7 0.36 12.62 0.84
118 INT210247 Positive_regulation of Bmp4 2 6 0.65 4.36 0.8
119 INT2244 Positive_regulation of Localization of GAST 2 7 0.68 5.28 0.73
120 INT153146 Positive_regulation of AIFM1 2 1 0.68 1.85 0.66
121 INT115276 Gene_expression of AKR1C1 1 11 0.77 4.65 0.63
122 INT84250 Positive_regulation of IDUA 4 8 0.56 15.89 0.62
123 INT164472 Binding of IBD9 1 1 0.32 0.58 0.62
124 INT124373 Positive_regulation of Gene_expression of Wnt2 1 14 0.42 8.28 0.6
125 INT158444 Positive_regulation of Cnp 1 6 0.63 5 0.55
126 INT84826 Negative_regulation of ACD 1 6 0.50 4.02 0.55
127 INT39246 Gene_expression of PGC 2 6 0.62 2.5 0.48
128 INT117687 Positive_regulation of TPSD1 1 5 0.44 2.63 0.46
129 INT338684 Localization of Aff3 1 1 0.61 0.2 0.44
130 INT338687 Negative_regulation of Localization of Aff3 1 1 0.34 0.2 0.44
131 INT165874 Phosphorylation of Cp 1 2 0.15 0 0.36
132 INT210251 Gene_expression of Tff3 32 1 0.75 1.06 0.36
133 INT190032 Negative_regulation of Cdx2 2 2 0.38 0.74 0.3
134 INT210245 Negative_regulation of Gene_expression of Tff3 7 1 0.56 0.75 0.29
135 INT114369 Positive_regulation of Tcf4 2 6 0.40 2.7 0.25
136 INT84244 Positive_regulation of Gene_expression of IDUA 2 5 0.70 3.75 0.19
137 INT190366 Binding of PPAN 1 2 0.32 1.2 0.19
138 INT235042 Gene_expression of PPAN 1 1 0.48 0.74 0.18
139 INT120085 Negative_regulation of Gene_expression of Bmp4 3 5 0.55 0.61 0.17
140 INT210249 Gene_expression of Tcf4 15 14 0.66 4.32 0.16
141 INT158445 Gene_expression of Npr2 1 3 0.36 1.19 0.15
142 INT210323 Negative_regulation of SLC4A7 5 1 0.08 0.36 0.15
143 INT153084 Positive_regulation of Gene_expression of AKR1C1 1 4 0.50 1.56 0.14
144 INT235041 Localization of PPAN 1 1 0.51 0.49 0.12
145 INT210322 Gene_expression of HR 4 6 0.54 0.05 0.1
146 INT111567 Positive_regulation of Gene_expression of Pgc 1 2 0.43 1.34 0.1
147 INT129929 Transcription of LDHA 1 4 0.17 4.48 0.08
148 INT296382 Positive_regulation of SLC11A2 2 3 0.31 1.49 0.08
149 INT279349 Localization of IDUA 3 7 0.76 4.97 0.07
150 INT210255 Positive_regulation of Negative_regulation of Cdx2 2 1 0.33 0 0.07
151 INT156009 Gene_expression of Pdlim7 1 1 0.57 0.37 0.07
152 INT210243 Negative_regulation of Bmp4 7 1 0.55 0.55 0.07
153 INT210242 Positive_regulation of Sox9 1 3 0.43 0.35 0.06
154 INT129204 Positive_regulation of Positive_regulation of MUC1 1 2 0.09 1.01 0.06
155 INT162956 Binding of ACD 1 3 0.32 3.04 0.05
156 INT210238 Positive_regulation of Negative_regulation of Bmp4 2 1 0.47 0 0.04
157 INT296384 Regulation of SLC40A1 1 2 0.01 0.83 0.03
158 INT230372 Negative_regulation of ELL 1 5 0.03 1.35 0
159 INT210244 Positive_regulation of Gene_expression of Tcf4 3 4 0.59 1.49 0
160 INT186639 Gene_expression of SLC11A2 2 4 0.65 1.91 0
161 INT296386 Localization of DEFA6 1 3 0.05 0.88 0
162 INT210250 Negative_regulation of Gene_expression of Tcf4 2 3 0.36 0.26 0
163 INT210246 Gene_expression of Pmel 3 3 0.16 2.27 0
164 INT210320 Positive_regulation of HR 2 3 0.56 0 0
165 INT210257 Regulation of Tcf4 1 2 0.27 0.59 0
166 INT142119 Regulation of Bmp4 1 2 0.58 0.29 0
167 INT210256 Positive_regulation of Tcf7l2 1 2 0.28 1.25 0
168 INT296387 Localization of SLC40A1 1 2 0.44 0.94 0
169 INT210319 Negative_regulation of HR 1 2 0.36 0.23 0
170 INT271773 Protein_catabolism of PGC 1 1 0.08 0.16 0
171 INT210239 Localization of Tff3 3 1 0.77 0.31 0
172 INT210241 Positive_regulation of Localization of Tff3 1 1 0.67 0.31 0
173 INT210253 Regulation of Gene_expression of Tcf4 1 1 0.23 0.09 0
174 INT296383 Regulation of SLC11A2 1 1 0.07 0.33 0
175 INT271772 Negative_regulation of Positive_regulation of MUC1 1 1 0.08 0 0
176 INT210248 Positive_regulation of Gene_expression of Tff3 2 1 0.67 0 0
177 INT210252 Regulation of Gene_expression of Tff3 2 1 0.43 0 0
178 INT210321 Localization of SLC4A7 2 1 0.11 0 0
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