J:Drugs Aging

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 1 0.01 1.2 0.79
2 INT16104 GNRH1 Positive_regulation of Lhb 2 1 0.03 0.53 0.14
3 INT16100 Gnrh1 Positive_regulation of Localization of Lhb 1 2 0.06 0.13 0
4 INT16103 GNRH1 Positive_regulation of Localization of Gnrh1 1 1 0.02 0.07 0
5 INT16101 Gnrh1 Positive_regulation of Lhb 1 2 0.06 0.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 1 2008 0.81 518.3 1408.65
2 INT50058 Negative_regulation of Cpox 3 907 0.58 426.28 428.29
3 INT76660 Gene_expression of Trpv1 1 691 0.78 329.46 386.42
4 INT6580 Negative_regulation of Ptgs1 1 929 0.59 381.53 376.26
5 INT439 Localization of Gnrh1 1 976 0.81 100.96 363.25
6 INT34869 Negative_regulation of PTGS2 2 778 0.59 366.76 319.85
7 INT2365 Positive_regulation of Cck 1 354 0.70 87.8 277.41
8 INT3948 Regulation of Cck 1 291 0.62 58.07 255.88
9 INT11377 Positive_regulation of Ngf 2 331 0.70 206.5 238
10 INT5127 Localization of Lhb 1 488 0.80 50.48 162.66
11 INT15515 Positive_regulation of Crp 2 700 0.70 604.24 150.15
12 INT8243 Positive_regulation of Il6 1 451 0.70 358.24 119.28
13 INT4742 Gene_expression of Tac1 1 177 0.78 69.99 102.66
14 INT65500 Gene_expression of App 3 605 0.78 429.94 98.31
15 INT6437 Binding of YY1 1 154 0.47 26.3 90.46
16 INT3657 Gene_expression of Ins1 1 514 0.78 321.69 75.76
17 INT1497 Negative_regulation of Gh 1 415 0.59 192.95 74.71
18 INT1080 Negative_regulation of Ache 1 343 0.59 108.51 72.4
19 INT15913 Negative_regulation of CYP2D6 1 174 0.59 22.45 70.91
20 INT2123 Positive_regulation of Gnrh1 3 209 0.70 24.2 68.97
21 INT2056 Negative_regulation of Gnrh1 1 175 0.59 33.43 63.32
22 INT1169 Negative_regulation of Bche 3 322 0.59 149.22 61.27
23 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
24 INT1200 Negative_regulation of Ins1 1 274 0.58 155.17 56.14
25 INT50405 Negative_regulation of CYP3A4 1 238 0.59 53.65 51.51
26 INT2197 Gene_expression of Gnrh1 1 184 0.78 40.04 50.57
27 INT98498 Binding of Trpv1 1 75 0.48 33.67 44.4
28 INT69992 Negative_regulation of Hmox2 3 93 0.50 49.01 44.07
29 INT51017 Positive_regulation of Icam1 2 113 0.70 81.16 35.55
30 INT5868 Positive_regulation of GNRH1 1 122 0.69 20.96 32.8
31 INT29743 Negative_regulation of App 3 91 0.59 65.56 31.26
32 INT47712 Positive_regulation of App 3 135 0.69 101.38 28.94
33 INT5135 Negative_regulation of GNRH1 1 106 0.58 36.63 27.71
34 INT2569 Gene_expression of Ache 1 120 0.78 26.29 26.89
35 INT2040 Positive_regulation of CYP2B6 1 95 0.69 34.3 25.6
36 INT48235 Negative_regulation of NPEPPS 1 72 0.46 44.54 25.03
37 INT48240 Binding of Ngf 1 46 0.46 23.51 24.42
38 INT5131 Gene_expression of GNRH1 1 109 0.78 28.79 23.94
39 INT2386 Gene_expression of Pgr 1 112 0.78 45.46 22.19
40 INT11157 Binding of EGF 1 88 0.48 53.73 21.25
41 INT76336 Negative_regulation of PDE5A 4 192 0.59 112.02 20.09
42 INT16794 Binding of App 1 103 0.48 64.87 19.79
43 INT53574 Regulation of Tnf 1 45 0.62 40.68 19.71
44 INT65502 Regulation of App 2 77 0.62 52.05 19.44
45 INT28951 Negative_regulation of IGF1 2 133 0.59 75.77 18.9
46 INT70970 Binding of COPD 1 144 0.42 180.34 18.29
47 INT1752 Negative_regulation of Ache 2 109 0.59 42.05 15.73
48 INT5333 Gene_expression of NPEPPS 1 45 0.65 26.34 15.25
49 INT2630 Positive_regulation of Shbg 2 134 0.70 65.26 15.19
50 INT7475 Positive_regulation of Hdl1 1 138 0.67 175.81 15.05
51 INT170 Negative_regulation of Adrb1 1 52 0.55 13.46 14.78
52 INT69743 Gene_expression of Hmox2 1 36 0.78 20.77 14.26
53 INT18773 Localization of ALB 1 117 0.80 69.18 13.8
54 INT18658 Regulation of Adra1a 1 34 0.62 5.69 13.78
55 INT60764 Positive_regulation of PPIG 1 39 0.67 17.08 13.48
56 INT4145 Gene_expression of FSHR 1 124 0.77 44.98 13.04
57 INT44 Positive_regulation of Adra1a 1 30 0.68 7.09 12.73
58 INT107916 Protein_catabolism of App 3 114 1.00 66.71 12.38
59 INT50580 Binding of PPIG 1 39 0.36 11.17 12.34
60 INT53038 Positive_regulation of Agtr1a 1 35 0.67 23.76 11.68
61 INT3602 Negative_regulation of Shbg 2 148 0.53 69.05 11.65
62 INT1190 Positive_regulation of F2 1 53 0.70 46.41 11.64
63 INT65501 Regulation of Gene_expression of App 1 56 0.62 32.51 11.48
64 INT98789 Negative_regulation of Gene_expression of App 2 54 0.58 40.27 11.15
65 INT158070 Localization of Aes 1 23 0.65 19.93 10.9
66 INT17349 Negative_regulation of Akr1b1 1 41 0.59 27.03 10.65
67 INT94004 Negative_regulation of Lox 1 31 0.59 13.76 10.45
68 INT39712 Binding of pad 1 82 0.48 110.92 10.33
69 INT2976 Regulation of Bche 1 29 0.45 8.56 9.42
70 INT1218 Negative_regulation of Maob 1 24 0.59 9.76 9.39
71 INT43820 Positive_regulation of Twist1 1 75 0.59 42.15 8.47
72 INT8637 Negative_regulation of Dbp 2 112 0.50 33.28 8.4
73 INT150422 Positive_regulation of Aes 1 24 0.43 15.63 8
74 INT1925 Gene_expression of PLAT 1 47 0.75 34.76 7.88
75 INT5164 Negative_regulation of Ldlr 2 83 0.58 55.01 7.87
76 INT27170 Gene_expression of Maoa 1 13 0.67 3.88 7.5
77 INT9785 Negative_regulation of Positive_regulation of Gnrh1 3 18 0.43 1.88 7.35
78 INT25647 Negative_regulation of Binding of YY1 1 10 0.57 1.47 6.77
79 INT1926 Positive_regulation of PLAT 1 54 0.66 31.42 6.49
80 INT95607 Regulation of MMP1 1 19 0.60 7.86 6.18
81 INT72110 Gene_expression of Glp1r 2 48 0.78 22.46 6.17
82 INT8337 Negative_regulation of Gene_expression of Gnrh1 1 14 0.58 4.63 5.32
83 INT7393 Negative_regulation of Positive_regulation of GNRH1 1 11 0.58 0.39 4.26
84 INT63977 Positive_regulation of Sele 1 28 0.68 18.49 4.17
85 INT110348 Negative_regulation of Dpp4 1 28 0.46 22.39 4.12
86 INT37380 Negative_regulation of Sis 1 31 0.55 19.89 3.92
87 INT17685 Negative_regulation of Cog1 1 23 0.42 15.65 3.56
88 INT36142 Negative_regulation of Hmgcr 3 33 0.46 15.91 3.54
89 INT8246 Positive_regulation of IL36RN 1 13 0.43 9.15 3.16
90 INT743 Negative_regulation of Salpa1 1 16 0.57 8.75 3.1
91 INT6063 Positive_regulation of Bche 1 17 0.66 6.07 3.08
92 INT10057 Gene_expression of Ldlr 1 35 0.67 23.99 3.05
93 INT16616 Negative_regulation of SRD5A1 1 44 0.57 34.81 2.96
94 INT9055 Positive_regulation of Cog1 1 22 0.68 14.08 2.95
95 INT56337 Regulation of Cyp1a2 1 8 0.27 1.09 2.33
96 INT104364 Localization of Hmox2 1 3 0.03 2.59 2.18
97 INT59737 Negative_regulation of Glp1r 2 15 0.43 6.94 2.01
98 INT64609 Negative_regulation of PLXNA3 1 5 0.57 3.64 1.94
99 INT32558 Negative_regulation of ADORA1 1 5 0.12 2.77 1.86
100 INT107915 Regulation of Negative_regulation of App 2 6 0.45 4.47 1.76
101 INT126094 Negative_regulation of Localization of Hmox2 1 2 0.02 1.63 1.69
102 INT71336 Negative_regulation of RNLS 1 4 0.58 3.42 1.61
103 INT133863 Positive_regulation of Protein_catabolism of App 2 12 0.59 7.53 1.52
104 INT114203 Positive_regulation of Bace2 2 6 0.52 4.89 1.46
105 INT25032 Negative_regulation of Gene_expression of FSHR 1 11 0.39 1.99 1.2
106 INT103043 Binding of PDE5A 1 16 0.37 7.79 1.12
107 INT66401 Positive_regulation of Renf1 1 2 0.01 2.21 0.85
108 INT16102 Negative_regulation of Gene_expression of GNRH1 1 5 0.39 0.85 0.64
109 INT85975 Gene_expression of Myoc 1 1 0.46 1.73 0.58
110 INT85976 Transcription of MYOC 1 1 0.16 1.68 0.55
111 INT58202 Regulation of TFF1 1 4 0.37 2.49 0.53
112 INT73768 Positive_regulation of Pip 1 5 0.59 0.26 0.52
113 INT133228 Protein_catabolism of Glp1r 1 8 0.88 2.65 0.48
114 INT130039 Protein_catabolism of Dpp4 1 5 0.66 3.03 0.47
115 INT65087 Positive_regulation of TFF1 1 4 0.49 6.5 0.45
116 INT153861 Binding of EPX 7 9 0.46 0.49 0.41
117 INT77891 Negative_regulation of Pip 2 3 0.50 0 0.4
118 INT65086 Positive_regulation of Regulation of TFF1 1 1 0.01 1.66 0.34
119 INT133862 Positive_regulation of Positive_regulation of Bace2 1 1 0.35 1.14 0.33
120 INT133860 Negative_regulation of Positive_regulation of Bace2 1 1 0.32 1.13 0.32
121 INT133864 Positive_regulation of Protein_catabolism of Psenen 1 1 0.09 0.9 0.19
122 INT133861 Protein_catabolism of Psenen 1 1 0.16 0.89 0.19
123 INT135472 Binding of Pip 4 2 0.41 0.1 0.1
124 INT161541 Binding of VMA21 1 1 0.00 0 0.1
125 INT155540 Negative_regulation of Protein_catabolism of Dpp4 1 1 0.03 1 0.07
126 INT155539 Negative_regulation of Protein_catabolism of Glp1r 1 1 0.10 0.99 0.07
127 INT153688 Negative_regulation of Negative_regulation of Hmgcr 1 1 0.42 1.21 0.06
128 INT153690 Localization of Hmgcr 1 1 0.74 1.21 0.06
129 INT153689 Negative_regulation of Localization of Hmgcr 1 1 0.42 1.21 0.06
130 INT153694 Transcription of Pip 1 1 0.59 0 0
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