J:Eur. Heart J.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT65560 Binding of Atp9b and ANGPTL5 2 1 0.10 0.34 0.13
2 INT65561 Binding of VWF and Atp9b 1 1 0.22 0.34 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2 2008 0.81 518.3 1408.65
2 INT9238 Gene_expression of IL6 2 1575 0.78 1135.66 424.22
3 INT467 Gene_expression of POMC 2 1048 0.78 332.8 394.16
4 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
5 INT16868 Gene_expression of Il6 2 807 0.78 499.48 256.57
6 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
7 INT626 Localization of CALCA 1 289 0.81 125.39 221.15
8 INT11313 Positive_regulation of Il6 2 526 0.70 331.27 201.59
9 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
10 INT15516 Gene_expression of Crp 3 711 0.77 615.33 173.09
11 INT15515 Positive_regulation of Crp 8 700 0.70 604.24 150.15
12 INT48895 Gene_expression of Il10 1 333 0.78 221.2 138.52
13 INT397 Localization of SST 1 232 0.81 58.05 101.19
14 INT5617 Localization of Nppa 4 266 0.81 83.51 83.89
15 INT48406 Gene_expression of Icam1 2 277 0.78 238.28 81.71
16 INT2893 Localization of Oxt 1 219 0.80 28.96 79.43
17 INT9408 Positive_regulation of Crp 7 296 0.69 242.27 57.35
18 INT314 Positive_regulation of Ren 2 212 0.70 66.68 55.56
19 INT5623 Positive_regulation of Nppa 1 174 0.70 69.96 52.33
20 INT22454 Regulation of Crp 1 213 0.62 160.67 49.24
21 INT375 Positive_regulation of REN 4 293 0.70 152.46 47.55
22 INT683 Positive_regulation of AVP 4 173 0.70 74.55 46.41
23 INT2774 Binding of Crp 2 241 0.48 195.89 44.39
24 INT49105 Gene_expression of Vcam1 1 157 0.78 157.27 43.01
25 INT47939 Gene_expression of Selp 2 171 0.76 87.54 39.03
26 INT3971 Positive_regulation of Alb 1 175 0.70 98.46 36.45
27 INT5620 Positive_regulation of Localization of Nppa 1 105 0.70 30.23 36.45
28 INT49 Negative_regulation of Ren 1 129 0.59 37.48 35.62
29 INT51017 Positive_regulation of Icam1 5 113 0.70 81.16 35.55
30 INT48896 Positive_regulation of Gene_expression of Il10 1 73 0.70 43.14 35.5
31 INT3679 Gene_expression of AVP 1 171 0.78 72.9 35.23
32 INT16960 Gene_expression of Crp 5 166 0.76 116.21 34.07
33 INT1179 Negative_regulation of Ace 4 157 0.59 67.03 30.46
34 INT4861 Localization of GRP 1 84 0.80 8.26 28.03
35 INT11361 Gene_expression of SERPINE1 2 183 0.78 136.45 27.97
36 INT2393 Positive_regulation of Mb 1 174 0.69 93.59 26.79
37 INT8205 Negative_regulation of Nppa 1 77 0.59 26.43 25.72
38 INT5622 Gene_expression of Nppa 4 101 0.78 49.46 25.31
39 INT2140 Regulation of REN 1 104 0.62 28.24 24.49
40 INT4465 Gene_expression of CEL 1 116 0.77 98.35 23.58
41 INT9079 Gene_expression of PPBP 2 52 0.75 31.2 21.52
42 INT2978 Gene_expression of Tbxa2r 1 76 0.77 28.4 21.27
43 INT6699 Positive_regulation of ADRA1D 1 65 0.70 22.72 20.31
44 INT5160 Localization of PTAFR 1 61 0.80 42.6 19.16
45 INT9552 Positive_regulation of TNNI3 1 209 0.70 128.67 19.15
46 INT2216 Gene_expression of SELL 1 92 0.77 59.29 17.71
47 INT5618 Regulation of Localization of Nppa 1 36 0.62 13.42 17.46
48 INT1533 Negative_regulation of AGT 1 105 0.42 46.54 16.92
49 INT899 Gene_expression of F13A1 1 122 0.70 78.02 16.26
50 INT615 Regulation of Alb 3 66 0.62 33.43 15.33
51 INT11636 Positive_regulation of SERPINE1 1 85 0.69 68.73 14.8
52 INT11071 Positive_regulation of PPBP 1 43 0.68 26.85 13.43
53 INT15921 Positive_regulation of Serpine1 2 85 0.68 81.24 13.4
54 INT3962 Regulation of AGT 1 50 0.62 20.96 13.01
55 INT36263 Positive_regulation of CEL 1 53 0.69 34.88 12.87
56 INT14764 Negative_regulation of Localization of Nppa 2 28 0.59 11.29 12.82
57 INT71510 Positive_regulation of Selp 1 47 0.68 30.43 12.8
58 INT9083 Gene_expression of Nppb 1 74 0.78 70.96 12.19
59 INT11121 Positive_regulation of NPPA 3 64 0.70 34.09 11.96
60 INT32203 Negative_regulation of Crp 3 48 0.58 32.77 11.89
61 INT4047 Binding of F13A1 5 105 0.43 66.54 11.81
62 INT41313 Gene_expression of Gpx1 2 68 0.78 34.24 11.77
63 INT1190 Positive_regulation of F2 1 53 0.70 46.41 11.64
64 INT398 Localization of AGT 1 45 0.78 16.97 11.54
65 INT37541 Gene_expression of SPP1 2 113 0.77 68.54 11.35
66 INT15238 Positive_regulation of NPY 1 24 0.67 11.86 11.26
67 INT14962 Gene_expression of Pf4 1 27 0.76 22.48 10.88
68 INT7132 Localization of NPPA 6 53 0.81 19.79 10.86
69 INT2791 Regulation of Mb 4 53 0.61 23.03 10.73
70 INT39712 Binding of pad 4 82 0.48 110.92 10.33
71 INT2792 Gene_expression of Mb 1 91 0.76 41.56 10.25
72 INT15449 Positive_regulation of Plat 1 32 0.69 12.76 9.71
73 INT57424 Positive_regulation of TNNT1 3 42 0.67 31.84 9.7
74 INT10139 Positive_regulation of F13A1 3 64 0.56 44.75 9.69
75 INT16356 Regulation of NPPA 2 33 0.62 13.24 9.53
76 INT11679 Negative_regulation of F13A1 1 55 0.54 33.69 9.43
77 INT9899 Gene_expression of Vwf 2 91 0.74 45.06 9.13
78 INT55597 Negative_regulation of Gpx1 1 59 0.55 28.3 8.83
79 INT591 Negative_regulation of Serpinc1 1 44 0.57 31.73 8.82
80 INT16460 Negative_regulation of PPBP 1 21 0.57 13.86 8.54
81 INT6133 Negative_regulation of Serpinc1 1 56 0.58 42.8 8.35
82 INT60034 Positive_regulation of VWF 1 40 0.68 30.42 8.15
83 INT2271 Gene_expression of F2 1 51 0.76 30.21 7.97
84 INT62944 Regulation of Icam1 2 33 0.47 23.52 7.94
85 INT10145 Gene_expression of Plg 2 28 0.62 12.68 7.46
86 INT125136 Regulation of Adipoq 1 24 0.56 16.82 7.23
87 INT6210 Binding of Nppa 1 39 0.47 14.35 7.21
88 INT10513 Gene_expression of Plat 1 44 0.76 19.49 7.17
89 INT15156 Positive_regulation of Localization of NPPA 3 21 0.70 8.61 6.97
90 INT24907 Gene_expression of PAPPA 1 42 0.75 28.32 6.63
91 INT2442 Localization of Mb 3 38 0.80 24.74 6.33
92 INT48270 Negative_regulation of RNF130 1 44 0.57 21.31 6.14
93 INT5146 Localization of PPBP 1 32 0.81 12.5 6.08
94 INT2890 Positive_regulation of MB 1 39 0.70 29.58 6.01
95 INT19941 Negative_regulation of Pf4 2 13 0.42 10.35 5.97
96 INT34742 Gene_expression of Gnat3 1 44 0.67 6.83 5.65
97 INT32458 Gene_expression of VWF 2 57 0.78 28.97 5.56
98 INT15367 Gene_expression of OPA1 1 35 0.67 24.9 5.45
99 INT16923 Positive_regulation of Tnni3 2 32 0.50 25.01 5.44
100 INT63957 Positive_regulation of Tnnt2 1 33 0.69 18.56 5.41
101 INT103518 Negative_regulation of SCN2A 1 17 0.57 8.4 5.4
102 INT3647 Positive_regulation of Gene_expression of F13A1 2 20 0.41 15.71 5.02
103 INT28145 Binding of PAPPA 1 26 0.48 7.4 4.96
104 INT5619 Positive_regulation of Gene_expression of Nppa 1 21 0.70 11.95 4.41
105 INT17020 Localization of AHSP 1 11 0.80 3.82 4.34
106 INT24332 Regulation of Hdl1 1 28 0.45 45.45 4.26
107 INT55741 Negative_regulation of Timp1 1 15 0.51 8.12 4.09
108 INT97128 Localization of SPP1 2 32 0.80 21.75 4.02
109 INT51831 Negative_regulation of ITGA2B 1 20 0.57 10.59 3.91
110 INT33735 Binding of ANGPTL5 1 39 0.32 14.23 3.66
111 INT25136 Localization of Gnat3 4 23 0.75 5.01 3.65
112 INT16608 Positive_regulation of FFAR1 1 40 0.37 18.48 3.59
113 INT27694 Positive_regulation of Positive_regulation of ADRA1D 1 10 0.70 1.52 3.57
114 INT38814 Positive_regulation of Aspt1 1 9 0.63 6.89 3.06
115 INT10057 Gene_expression of Ldlr 1 35 0.67 23.99 3.05
116 INT1177 Positive_regulation of Positive_regulation of Ren 1 16 0.70 6.11 3
117 INT41358 Localization of Pf4 1 11 0.79 6.06 2.89
118 INT17769 Positive_regulation of Dnase1 2 5 0.69 4.21 2.86
119 INT10893 Binding of VWF 1 27 0.47 25.02 2.82
120 INT51861 Gene_expression of Rdh11 1 8 0.11 2.26 2.82
121 INT30870 Negative_regulation of Adra2b 1 8 0.44 4.5 2.8
122 INT74216 Binding of Icam1 1 16 0.48 10.11 2.69
123 INT15744 Localization of GYPA 1 12 0.64 7.19 2.61
124 INT25449 Positive_regulation of Gene_expression of PPBP 1 5 0.46 3.77 2.57
125 INT23954 Negative_regulation of Mb 1 24 0.49 11.27 2.55
126 INT5180 Binding of Serpinc1 1 27 0.36 13.39 2.47
127 INT22019 Regulation of GHR 2 9 0.62 2.56 2.39
128 INT93009 Regulation of HBN1 1 24 0.17 17.6 2.03
129 INT48035 Positive_regulation of NT5C2 1 5 0.67 2.42 1.91
130 INT15155 Regulation of Localization of NPPA 3 8 0.62 2.67 1.65
131 INT25445 Binding of Plat 1 7 0.41 12.75 1.63
132 INT38025 Negative_regulation of Tlf 1 3 0.24 1.11 1.63
133 INT22329 Gene_expression of Ptprc 1 36 0.66 15.84 1.59
134 INT38831 Regulation of SELL 1 9 0.20 5.82 1.56
135 INT11365 Positive_regulation of Localization of Mb 2 5 0.38 3.78 1.54
136 INT39444 Negative_regulation of Positive_regulation of F2 1 7 0.59 5.82 1.42
137 INT47434 Gene_expression of Tnnt2 1 14 0.60 10.4 1.37
138 INT55476 Negative_regulation of ITGA2 1 8 0.55 3.55 1.33
139 INT90771 Positive_regulation of Ptprc 1 20 0.48 8.43 1.27
140 INT11367 Localization of MB 2 9 0.78 9.34 1.24
141 INT55599 Gene_expression of GSX1 1 3 0.65 3.72 1.23
142 INT81776 Positive_regulation of F3 3 8 0.07 3.77 1.21
143 INT74521 Negative_regulation of ERAL1 1 3 0.42 2.78 1.13
144 INT150 Negative_regulation of CXCL11 1 4 0.57 3.34 1.12
145 INT22139 Negative_regulation of Phdlc1 1 7 0.25 5.19 1.06
146 INT72715 Positive_regulation of Nppc 1 4 0.39 1.55 0.87
147 INT33733 Binding of ITGA2B 1 12 0.36 3.86 0.71
148 INT147516 Positive_regulation of Positive_regulation of Dnase1 1 2 0.50 1.3 0.67
149 INT55598 Regulation of GSX1 1 1 0.44 0.95 0.55
150 INT55600 Regulation of Gene_expression of GSX1 1 1 0.44 0.96 0.55
151 INT24903 Negative_regulation of Gene_expression of PAPPA 1 6 0.42 2.98 0.52
152 INT12343 Protein_catabolism of PLAT 1 2 0.76 0.73 0.44
153 INT60035 Regulation of VWF 1 6 0.42 6.26 0.4
154 INT72717 Gene_expression of Nppc 2 8 0.51 6.25 0.39
155 INT15965 Localization of Srv 1 2 0.61 0.58 0.38
156 INT49830 Binding of SCNM1 1 1 0.37 0 0.34
157 INT4463 Regulation of SCN2A 1 3 0.44 0.78 0.3
158 INT45627 Negative_regulation of Positive_regulation of SMARCA1 1 1 0.42 0.58 0.3
159 INT45628 Positive_regulation of SMARCA1 1 1 0.67 0.57 0.29
160 INT111046 Regulation of Npy1r 1 1 0.31 0.27 0.25
161 INT11366 Positive_regulation of Localization of MB 1 2 0.33 1.6 0.22
162 INT89580 Negative_regulation of STAR 1 16 0.35 14.88 0.2
163 INT36492 Positive_regulation of Tlf 1 2 0.26 1.51 0.15
164 INT25137 Positive_regulation of Localization of Gnat3 1 1 0.40 0.21 0.14
165 INT72716 Localization of Nppc 1 2 0.06 0.29 0
166 INT106285 Positive_regulation of Regulation of VWF 1 1 0.10 0 0
167 INT72714 Negative_regulation of Localization of Nppc 1 1 0.02 0.05 0
168 INT123997 Positive_regulation of Corin 1 1 0.01 0.08 0
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