J:Eur. J. Immunol.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT126335	Binding of Pax3 and Tac1	6	1	0.07	6.22	5.27
2	INT55837	Binding of HLA-B and PHB2	3	1	0.20	3.52	1.37
3	INT103928	Binding of Cd28 and Trav6-3	3	2	0.03	0.55	0.98
4	INT103933	Cps1 Negative_regulation of Gene_expression of Cd69	1	2	0.03	0.25	0.93
5	INT103930	Cps1 Negative_regulation of Gene_expression of Il2ra	1	2	0.02	0.25	0.93
6	INT73492	PTGER2 Positive_regulation of Gene_expression of IL4	1	2	0.08	1.11	0.87
7	INT126341	Tac1 Regulation of Gene_expression of Tnfrsf10b	1	1	0.06	0.71	0.52
8	INT103937	Cps1 Negative_regulation of Gene_expression of Cd28	1	1	0.03	0.19	0.51
9	INT103932	Cps1 Negative_regulation of Gene_expression of Trav6-3	1	1	0.01	0.19	0.5
10	INT103934	Cps1 Negative_regulation of Positive_regulation of Nfkb1	1	1	0.02	0.2	0.49
11	INT126336	Negative_regulation of Binding of Pax3 and Tac1	1	1	0.01	0.66	0.49
12	INT103929	Cps1 Negative_regulation of Gene_expression of Icam1	1	1	0.01	0.13	0.47
13	INT103936	Cps1 Negative_regulation of Il2ra	1	1	0.02	0.07	0.46
14	INT103931	Cps1 Negative_regulation of Icam1	1	1	0.01	0.07	0.46
15	INT103935	Cps1 Negative_regulation of Cd69	1	1	0.03	0.07	0.46
16	INT126337	Pax3 Positive_regulation of Gene_expression of Ifng	1	1	0.05	0.56	0.44
17	INT126339	Pax3 Regulation of Insrr	1	1	0.00	0.56	0.44
18	INT126340	Pax3 Regulation of Gene_expression of Ifng	1	1	0.03	0.56	0.44
19	INT126338	Insrr Regulation of Gene_expression of Ifng	1	1	0.00	0.56	0.43
20	INT73494	PTGER2 Positive_regulation of Gene_expression of IL12A	1	1	0.05	0.51	0.33
21	INT73493	PTGER2 Negative_regulation of Gene_expression of IL12A	1	1	0.04	0.51	0.33
22	INT61266	Nfkb1 Regulation of Gene_expression of Itgam	1	1	0.23	0.65	0.32
23	INT61265	Nfkb1 Regulation of Gene_expression of Sele	1	1	0.28	0.65	0.32
24	INT93352	Ifng Positive_regulation of Positive_regulation of Fas	1	1	0.26	0.17	0.27

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT6483	Gene_expression of TNF	4	3152	0.78	2515.62	929.82
2	INT11624	Gene_expression of OPRM1	1	445	0.78	72.36	294.36
3	INT87687	Positive_regulation of Trpv1	2	409	0.70	210.24	257.59
4	INT6482	Positive_regulation of Gene_expression of TNF	2	659	0.70	569.88	210
5	INT6488	Gene_expression of Tnf	2	484	0.78	339.61	191.58
6	INT867	Gene_expression of IFNA1	1	930	0.78	594.85	168.03
7	INT66280	Gene_expression of Nos2	5	534	0.78	330.78	157.07
8	INT5116	Gene_expression of IL2	2	670	0.78	291.13	146.69
9	INT60694	Gene_expression of Il10	1	567	0.78	369.48	143.69
10	INT4658	Binding of OPRM1	1	188	0.48	25.96	136.24
11	INT1878	Binding of HLA-B	11	440	0.48	321.16	127.36
12	INT20374	Gene_expression of Il4	1	515	0.76	306.15	114.12
13	INT27096	Positive_regulation of Nfkb1	2	325	0.70	195.11	109.06
14	INT60526	Gene_expression of IL10	2	449	0.78	292.71	107.84
15	INT4742	Gene_expression of Tac1	1	177	0.78	69.99	102.66
16	INT77435	Positive_regulation of Nos2	2	343	0.70	208.49	91.43
17	INT96917	Positive_regulation of Mapk14	1	261	0.70	173.29	88.79
18	INT54571	Positive_regulation of NFKB1	1	263	0.70	138.99	87.32
19	INT749	Gene_expression of HLA-B	2	341	0.75	224.12	77.37
20	INT16654	Gene_expression of Insrr	1	138	0.46	58.96	75.68
21	INT15769	Gene_expression of Il1b	1	146	0.78	114.51	75.35
22	INT5056	Gene_expression of IFNG	11	216	0.78	137.52	74.57
23	INT56298	Gene_expression of IL4	5	306	0.78	182.18	72.92
24	INT6490	Negative_regulation of ADCY1	1	145	0.58	26.25	70.96
25	INT7534	Gene_expression of Ifng	5	193	0.78	111.02	68.6
26	INT6486	Positive_regulation of Tnf	1	168	0.70	123.47	66.05
27	INT103924	Positive_regulation of Akt1	1	359	0.69	158.94	60.34
28	INT14740	Gene_expression of TGFB1	1	272	0.78	168.48	60.18
29	INT62543	Gene_expression of Icam1	1	231	0.78	187.58	52.71
30	INT66029	Negative_regulation of Tnf	1	100	0.59	84.28	48.16
31	INT789	Positive_regulation of YY1	1	69	0.67	14.07	47.06
32	INT55670	Negative_regulation of Gene_expression of Tnf	2	83	0.59	57.16	46.33
33	INT8713	Regulation of Tac1	1	56	0.60	25.29	45.94
34	INT18522	Positive_regulation of Gene_expression of IFNA1	1	248	0.67	160.85	44.87
35	INT73502	Positive_regulation of IL10	1	154	0.69	124.87	43.5
36	INT60695	Positive_regulation of Gene_expression of Il10	1	154	0.70	120.28	43.07
37	INT4850	Binding of Tac1	1	57	0.47	14.25	42.17
38	INT61619	Gene_expression of IL12A	1	194	0.77	146.07	41.97
39	INT77434	Positive_regulation of Gene_expression of Nos2	2	151	0.69	96.76	38.94
40	INT49214	Gene_expression of Cd4	2	269	0.78	154.22	34.05
41	INT73498	Gene_expression of IL13	3	117	0.44	83.85	32.26
42	INT73982	Gene_expression of Hmox1	4	141	0.78	119.43	32.17
43	INT7538	Negative_regulation of IL2	1	95	0.57	47.31	31.7
44	INT54302	Positive_regulation of Gene_expression of Il4	1	126	0.68	86.18	30.75
45	INT9993	Positive_regulation of Gene_expression of IL2	1	131	0.69	46.27	30.04
46	INT6660	Positive_regulation of Jun	1	148	0.69	67.58	29.73
47	INT15174	Gene_expression of Itgam	2	238	0.73	104.92	29.26
48	INT87212	Negative_regulation of Positive_regulation of Nfkb1	1	74	0.57	38.21	28.31
49	INT52722	Localization of RETNLB	2	54	0.38	48.63	27.98
50	INT69157	Gene_expression of IL5	1	127	0.77	102.58	26.81
51	INT70048	Positive_regulation of Gene_expression of IL10	2	90	0.55	71.34	25.66
52	INT43486	Positive_regulation of Ifng	1	52	0.69	32.71	24.77
53	INT66758	Binding of Nfkb1	1	97	0.48	50.65	23.65
54	INT5055	Positive_regulation of IFNG	1	89	0.69	64.03	23.05
55	INT55170	Gene_expression of NFKB1	1	97	0.77	52.75	23.04
56	INT96741	Gene_expression of Cxcr4	1	62	0.78	32.3	22.14
57	INT1876	Positive_regulation of HLA-B	1	82	0.69	52.16	21.08
58	INT52529	Regulation of Nfkb1	1	48	0.61	26.2	20.89
59	INT62042	Positive_regulation of Gene_expression of IL4	4	67	0.56	42.05	20.39
60	INT636	Binding of MRAP	1	54	0.48	40.36	18.77
61	INT19509	Localization of Ifng	1	55	0.78	28.25	18.67
62	INT56301	Positive_regulation of IL4	1	68	0.56	54.51	18.65
63	INT35086	Positive_regulation of Gene_expression of Ifng	1	40	0.69	22.55	18.35
64	INT70145	Gene_expression of Trav6-3	1	136	0.76	69.6	18.05
65	INT61257	Gene_expression of Sele	2	79	0.77	70.97	17.78
66	INT35487	Localization of PTGER2	1	103	0.46	51.24	17.45
67	INT24209	Negative_regulation of Ifng	2	37	0.57	16.52	17.15
68	INT10187	Gene_expression of Il2ra	2	91	0.78	52.67	16.66
69	INT22900	Positive_regulation of Cd4	1	126	0.67	82.77	16.43
70	INT81627	Gene_expression of Fas	1	120	0.78	115.51	15.36
71	INT80228	Positive_regulation of Gene_expression of Hmox1	1	68	0.70	62.88	14.01
72	INT81629	Positive_regulation of Fas	1	58	0.70	59.63	12.94
73	INT58226	Negative_regulation of Gene_expression of Il1b	1	24	0.57	18.09	12.68
74	INT5057	Negative_regulation of Gene_expression of IFNG	1	23	0.58	8.33	12.3
75	INT70555	Regulation of Pax3	1	13	0.35	3.62	12.05
76	INT11794	Gene_expression of Cd2	1	27	0.76	17.31	10.99
77	INT19944	Negative_regulation of IFNG	1	39	0.58	22.35	10.91
78	INT128364	Positive_regulation of Ccl3	1	20	0.70	23.96	10.65
79	INT103923	Negative_regulation of Positive_regulation of Mapk14	1	23	0.53	13.95	10.64
80	INT60434	Negative_regulation of Positive_regulation of Tnf	1	20	0.46	10.01	10.64
81	INT15804	Gene_expression of ISG20	1	83	0.75	44.33	10.58
82	INT48806	Negative_regulation of Binding of Tac1	1	11	0.56	0.83	10.52
83	INT130867	Gene_expression of TNFSF11	6	106	0.77	45.15	10.34
84	INT15172	Positive_regulation of Itgam	2	45	0.67	23.54	10.3
85	INT10019	Binding of CD8A	1	57	0.36	31.49	10.08
86	INT73504	Binding of CD28	1	35	0.45	15.99	10.04
87	INT637	Positive_regulation of MRAP	1	23	0.67	21.13	9.97
88	INT149069	Positive_regulation of Cxcr4	1	24	0.68	12.21	9.54
89	INT73497	Regulation of IL10	1	33	0.45	22.6	9.19
90	INT61264	Regulation of Jun	1	36	0.61	18.42	8.71
91	INT19185	Negative_regulation of Cd4	1	80	0.51	61.32	8.51
92	INT17024	Gene_expression of COL1A2	1	69	0.77	36.38	8.29
93	INT94125	Gene_expression of Cd28	1	38	0.67	21.73	7.75
94	INT18190	Regulation of DRD2	1	11	0.60	9.01	7.63
95	INT103925	Negative_regulation of Positive_regulation of Akt1	1	32	0.58	15.19	7.39
96	INT5822	Gene_expression of Ltb4r1	3	51	0.76	37.43	7.2
97	INT50255	Regulation of Cd4	1	39	0.49	29.73	6.77
98	INT73499	Positive_regulation of IL13	1	23	0.39	20.03	6.53
99	INT11048	Gene_expression of CD69	1	59	0.67	42.85	6.4
100	INT116398	Gene_expression of Mog	1	25	0.77	23.11	6.33
101	INT61258	Transcription of Nfkb1	1	24	0.67	10.89	6.32
102	INT104547	Negative_regulation of Il18	1	24	0.59	17.89	6.01
103	INT56445	Regulation of Icam1	1	14	0.39	15.4	5.32
104	INT16405	Regulation of CD8A	1	38	0.45	19.04	5.31
105	INT93484	Negative_regulation of Positive_regulation of Jun	1	30	0.58	9.31	5.18
106	INT61252	Negative_regulation of Gene_expression of Itgam	1	38	0.54	16.48	5.01
107	INT103155	Gene_expression of KDR	1	78	0.66	50.53	4.38
108	INT89103	Regulation of Gene_expression of TGFB1	1	15	0.56	8.11	4.37
109	INT32446	Localization of Tyr	1	11	0.68	1.31	4.25
110	INT73503	Positive_regulation of Gene_expression of IL13	2	16	0.37	14.6	4.23
111	INT20925	Binding of ANTXR1	1	15	0.01	4.2	3.8
112	INT103926	Gene_expression of Cd69	2	37	0.68	16.76	3.58
113	INT76339	Positive_regulation of Ltb4r1	1	23	0.45	22.78	3.58
114	INT61253	Negative_regulation of Sele	1	13	0.57	11.68	3.56
115	INT73500	Regulation of IL13	1	12	0.36	10.37	3.53
116	INT61259	Negative_regulation of Itgam	1	16	0.47	11.11	3.27
117	INT21678	Negative_regulation of B2m	2	20	0.55	10.11	3.12
118	INT130865	Positive_regulation of TNFSF11	2	29	0.69	12.82	2.99
119	INT21350	Negative_regulation of Ltb4r1	2	11	0.33	6.77	2.88
120	INT30815	Binding of ADCY1	1	7	0.36	0.21	2.79
121	INT15197	Regulation of Gene_expression of Ifng	1	8	0.34	2.66	2.69
122	INT69009	Regulation of Binding of Nfkb1	1	9	0.27	9.86	2.58
123	INT128365	Positive_regulation of Gene_expression of Ltb4r1	1	10	0.60	8.04	2.53
124	INT149068	Regulation of Cxcr4	1	3	0.44	3.77	2.46
125	INT67796	Negative_regulation of CTLA4	1	13	0.39	8.36	2.39
126	INT38871	Binding of TFPI	1	12	0.32	5.9	2.36
127	INT61255	Negative_regulation of Transcription of Nfkb1	1	6	0.23	2.79	2.2
128	INT61262	Negative_regulation of Positive_regulation of Itgam	2	5	0.57	4.25	1.95
129	INT25402	Binding of Ptcra	1	10	0.34	3.54	1.85
130	INT73501	Negative_regulation of Localization of RETNLB	2	5	0.01	3.96	1.83
131	INT130866	Positive_regulation of Gene_expression of TNFSF11	2	25	0.69	7.11	1.82
132	INT61256	Negative_regulation of Transcription of Sele	1	2	0.43	1.24	1.6
133	INT61261	Transcription of Sele	1	2	0.53	1.24	1.58
134	INT93350	Binding of Lepr	1	17	0.05	27.21	1.5
135	INT8707	Localization of LILRB1	1	2	0.60	1.5	1.5
136	INT57973	Positive_regulation of ITGB1	1	5	0.67	1.23	1.44
137	INT126334	Gene_expression of Tnfrsf10b	1	8	0.58	8.68	1.42
138	INT61263	Negative_regulation of Gene_expression of Sele	1	6	0.43	5.65	1.31
139	INT128361	Negative_regulation of Positive_regulation of Ltb4r1	1	3	0.37	2.74	1.31
140	INT105270	Positive_regulation of KDR	1	25	0.49	11.49	1.2
141	INT22353	Positive_regulation of Cps1	1	6	0.17	0.98	1.14
142	INT135527	Negative_regulation of Gene_expression of Cd4	1	17	0.43	6.72	1.09
143	INT8703	Localization of Mpz	1	2	0.73	0.68	0.97
144	INT80871	Negative_regulation of Binding of ADCY1	1	1	0.03	0.1	0.91
145	INT108968	Regulation of Mpz	1	6	0.54	2.9	0.7
146	INT116396	Negative_regulation of Mog	1	4	0.46	2.85	0.63
147	INT55838	Gene_expression of RPL21P109	1	1	0.02	0.8	0.57
148	INT128360	Negative_regulation of Positive_regulation of Ccl3	1	2	0.41	1.86	0.55
149	INT128363	Negative_regulation of Gene_expression of Ltb4r1	3	5	0.50	2.53	0.52
150	INT8704	Positive_regulation of Localization of Mpz	1	1	0.49	0.69	0.47
151	INT8706	Positive_regulation of Localization of LILRB1	1	1	0.00	0.69	0.47
152	INT108969	Transcription of Mpz	1	2	0.72	1.26	0.45
153	INT11607	Binding of Aen	3	1	0.47	0.1	0.41
154	INT20436	Phosphorylation of CD3G	3	1	0.03	0	0.38
155	INT61254	Positive_regulation of Transcription of Sele	1	1	0.52	0.72	0.37
156	INT151373	Binding of CLDN11	1	1	0.36	0.84	0.29
157	INT128366	Negative_regulation of Positive_regulation of Csrp3	2	1	0.00	0.91	0.28
158	INT128362	Positive_regulation of Csrp3	2	1	0.01	0.9	0.27
159	INT116397	Positive_regulation of Gene_expression of Mog	1	2	0.49	2.08	0.25
160	INT11608	Binding of DAZL	1	1	0.00	0	0.15
161	INT42050	Regulation of Tsn	1	1	0.09	0	0.15
162	INT20433	Regulation of Phosphorylation of CD4	1	1	0.06	0	0.13
163	INT20434	Phosphorylation of CD4	1	2	0.61	0	0.12
164	INT20435	Regulation of Phosphorylation of CD3G	1	1	0.02	0	0.12
165	INT42049	Positive_regulation of Tsn	1	1	0.15	0	0