J:Eur. J. Pharmacol.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT66535 Binding of Pnoc and Oprl1 43 6 0.54 5.93 32.4
2 INT68514 Pnoc Positive_regulation of Oprl1 10 2 0.59 3.56 9.57
3 INT21276 Binding of Oprd1 and Penk 9 1 0.54 1.14 8.28
4 INT34444 Binding of Oprl1 and Ptprg 4 2 0.03 0.18 4.58
5 INT64480 Binding of OPRL1 and PNOC 2 4 0.33 0.23 4.38
6 INT111758 Binding of Drd2 and Insrr 1 3 0.01 0.94 4.33
7 INT7022 Drd1a Positive_regulation of Npr1 6 3 0.05 0.26 4.32
8 INT40114 Binding of OPRD1 and Oprm1 2 1 0.00 0 4.29
9 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 4 0.30 0.91 4.18
10 INT130625 Prkcg Regulation of Prkaca 1 2 0.23 1.32 3.87
11 INT143946 Binding of Pebp1 and Mastl 1 4 0.00 2.04 3.82
12 INT15984 Binding of Avp and Oxt 11 2 0.32 1.33 3.64
13 INT29837 Gnrh1 Positive_regulation of LH 6 1 0.67 0 3.53
14 INT73071 Binding of Cpe and Insrr 3 1 0.01 0.33 3.38
15 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 2 0.02 0.64 2.89
16 INT83169 Binding of Cck and Lep 7 2 0.42 1.58 2.78
17 INT7888 Oprl1 Regulation of Localization of Avp 4 1 0.49 0.25 2.63
18 INT150596 Binding of Oprd1 and Oprk1 1 2 0.08 0.14 2.59
19 INT76776 Binding of Pnoc and Ptprg 2 1 0.02 0 2.29
20 INT40408 Positive_regulation of Gnrh1 Positive_regulation of LH 2 1 0.58 0 2.21
21 INT66803 Oxt Regulation of Avp 7 1 0.16 0.19 2.15
22 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 3 0.33 0.53 2.1
23 INT33756 Akr1d1 Positive_regulation of Npr1 3 2 0.01 0 2.05
24 INT83170 Lep Regulation of Cck 5 3 0.43 0.68 1.96
25 INT6931 Binding of Oprk1 and Pdyn 2 1 0.24 0.92 1.92
26 INT83418 Binding of OPRL1 and Ntrk1 1 2 0.02 0 1.91
27 INT82867 Cck Regulation of Localization of Pgc 1 3 0.05 0 1.83
28 INT72468 Negative_regulation of Binding of OPRL1 and PNOC 1 2 0.40 0 1.83
29 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 1 0.05 0.1 1.81
30 INT6407 Binding of Lama5 and Oprm1 1 1 0.02 0.08 1.72
31 INT18786 Binding of Adra2a and Nisch 2 1 0.19 0 1.7
32 INT108385 Binding of Crygs and Ntrk1 1 2 0.01 0 1.67
33 INT142437 Urb1 Negative_regulation of Faah 3 2 0.41 2.12 1.66
34 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 1 0.17 0.38 1.65
35 INT24157 Binding of CALCA and SFTPA1 2 1 0.07 0.96 1.64
36 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 1 0.10 0.38 1.64
37 INT61049 Binding of Oprd1 and Negative_regulation of Gene_expression of Odc1 1 2 0.21 0 1.64
38 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 1 0.16 0.92 1.63
39 INT45816 Binding of Car2 and Gabrg1 2 1 0.28 0.15 1.63
40 INT33757 Hmmr Positive_regulation of Npr1 1 2 0.01 0 1.59
41 INT33759 Hmmr Positive_regulation of Akr1d1 1 2 0.00 0 1.58
42 INT83416 Binding of OPRK1 and Ntrk1 1 2 0.02 0 1.45
43 INT111760 Dio1 Positive_regulation of Binding of Cpe 1 1 0.04 0.34 1.44
44 INT69337 Oprm1 Positive_regulation of Atxn2l 1 1 0.01 0.27 1.43
45 INT111761 Positive_regulation of Binding of Cpe and Insrr 1 1 0.01 0.33 1.43
46 INT111756 Dio1 Positive_regulation of Cpe 1 1 0.04 0.34 1.42
47 INT111759 Binding of Cpe and Drd2 1 1 0.01 0.32 1.42
48 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 1 0.02 0.33 1.42
49 INT134760 Ghrl Regulation of Transcription of Calca 1 3 0.24 2.71 1.42
50 INT75370 Positive_regulation of Binding of Hrh1 and RGD735065 1 1 0.00 0.56 1.41
51 INT142852 Oprm1 Positive_regulation of Oprd1 1 1 0.41 0.06 1.41
52 INT75371 Binding of Hrh1 and RGD735065 1 1 0.00 0.55 1.4
53 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 3 0.02 2.66 1.4
54 INT131949 ANTXR1 Positive_regulation of NAV1 1 1 0.03 0.23 1.38
55 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 1 0.16 0.17 1.35
56 INT145473 Mastl Positive_regulation of Dnahc8 1 3 0.07 0.06 1.33
57 INT121457 KNG1 Positive_regulation of Trpv1 1 2 0.16 0.91 1.33
58 INT116102 Cck Positive_regulation of Negative_regulation of Pnoc 1 1 0.51 0.41 1.33
59 INT59446 Rbm39 Positive_regulation of Negative_regulation of Pomc 1 2 0.03 0.19 1.32
60 INT57263 Binding of Oprd1 and Atxn2l 1 1 0.02 0 1.29
61 INT57262 Binding of Gria4 and Oprd1 1 1 0.06 0 1.29
62 INT73398 Binding of Pnoc and Nr1d2 1 2 0.10 0 1.27
63 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 1 0.34 0 1.26
64 INT121465 Binding of Dnm2 and Oprm1 1 1 0.23 0 1.24
65 INT7887 Oprl1 Regulation of Localization of Oxt 2 1 0.16 0 1.23
66 INT150595 Binding of Oprk1 and Insrr 1 1 0.01 0.07 1.23
67 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 2 0.29 1.24 1.22
68 INT90644 Slc6a3 Positive_regulation of Th 1 4 0.51 0 1.2
69 INT20929 Binding of Trim13 and Vas1 1 2 0.10 0 1.18
70 INT76256 Binding of Slc6a3 and Sigmar1 1 2 0.20 0 1.16
71 INT76199 CASP1 Positive_regulation of CEL 1 2 0.06 0.32 1.14
72 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 1 0.04 0.07 1.13
73 INT130627 Gnas Regulation of Prkaca 1 1 0.00 0 1.13
74 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 1 0.24 0 1.11
75 INT69338 Binding of Oprd1 and Oprm1 1 1 0.24 0.26 1.11
76 INT61053 Adarb1 Positive_regulation of Pomc Negative_regulation of Odc1 1 2 0.01 0 1.1
77 INT90145 Binding of OPRL1 and OPRM1 2 1 0.27 0.31 1.08
78 INT85718 pcp Regulation of Npy 1 1 0.03 0 1.07
79 INT6415 Binding of Cpe and Oprd1 1 2 0.00 0 1.07
80 INT25837 Binding of Dbp and Oprl1 1 1 0.10 0 1.05
81 INT86073 Med15 Regulation of Calca 1 1 0.49 0.2 1.03
82 INT6930 Binding of Oprk1 and Pomc 1 1 0.08 0.16 1.01
83 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 1 0.04 0.08 1.01
84 INT60208 Binding of Htr1a and Htr2c 2 1 0.52 0.25 1
85 INT71000 Positive_regulation of Adarb1 Positive_regulation of Odc1 1 1 0.01 0 1
86 INT32327 POMC Positive_regulation of Localization of PRL 4 2 0.45 0 0.99
87 INT141384 Urb1 Regulation of Faah 2 1 0.08 0.35 0.99
88 INT44143 Negative_regulation of Thop1 Negative_regulation of Protein_catabolism of Penk 1 1 0.46 0 0.99
89 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 2 0.05 0 0.99
90 INT89828 Atp4b Positive_regulation of Localization of Grip2 1 2 0.10 0.54 0.97
91 INT36682 Gh1 Regulation of Gene_expression of Gnrhr 2 1 0.08 0 0.96
92 INT83415 Binding of Oprm1 and Ntrk1 1 1 0.01 0 0.96
93 INT36683 Gh1 Regulation of Gnrhr 3 1 0.08 1.25 0.95
94 INT127263 Adra2a Regulation of Gene_expression of Jun 1 2 0.07 1.1 0.95
95 INT42482 Binding of Cpe and Pebp1 1 1 0.02 0 0.95
96 INT144902 Binding of Trpv1 and Pars2 1 2 0.17 0 0.95
97 INT153685 Binding of Bcl2l11 and Gtpbp4 1 1 0.08 0.76 0.93
98 INT55564 Binding of Oprk1 and Pde6b 1 1 0.01 0 0.92
99 INT135446 Map2k1 Positive_regulation of Mapk3 1 1 0.54 0.25 0.91
100 INT124742 ARSA Positive_regulation of Localization of CSF2 1 1 0.10 0.15 0.91
101 INT72463 NA Positive_regulation of Binding of OPRL1 and PNOC 1 1 0.04 0 0.91
102 INT72464 Positive_regulation of Binding of OPRL1 and PNOC 1 1 0.34 0 0.91
103 INT56779 Pomc Negative_regulation of Gene_expression of Odc1 2 1 0.31 0 0.89
104 INT56500 Ide Regulation of Maoa 1 1 0.21 0 0.89
105 INT61046 Oprm1 Positive_regulation of Gh1 1 1 0.21 0 0.89
106 INT83417 Binding of OPRL1 and Oprm1 1 1 0.01 0 0.89
107 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 1 0.29 0 0.89
108 INT142278 Slc8a1 Regulation of Tnf 1 1 0.14 0.07 0.89
109 INT48455 Scd1 Regulation of Penk 1 1 0.06 0 0.88
110 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 1 0.16 0 0.88
111 INT61045 Oprm1 Positive_regulation of Prl 1 1 0.16 0 0.88
112 INT121467 Binding of Avp and Ptafr 1 2 0.11 0.98 0.88
113 INT72467 Regulation of Binding of OPRL1 and PNOC 1 1 0.18 0 0.86
114 INT133176 Regulation of Mastl Negative_regulation of Il12a 1 1 0.01 0.24 0.86
115 INT133177 Mastl Negative_regulation of Il12a 1 1 0.01 0.24 0.86
116 INT124743 ARSA Negative_regulation of PTGER2 1 1 0.03 0.15 0.85
117 INT124744 ARSA Negative_regulation of Gene_expression of PTGER2 1 1 0.03 0.15 0.85
118 INT84414 Folr2 Regulation of Binding of Oprd1 1 1 0.03 0.18 0.84
119 INT113972 Regulation of Binding of Oprd1 and Smu1 1 1 0.00 0.45 0.84
120 INT113971 Binding of Oprd1 and Smu1 1 1 0.00 0.45 0.84
121 INT145472 D2Mit212 Positive_regulation of Dnahc8 1 2 0.09 0.16 0.81
122 INT61052 Binding of Adarb1 and Negative_regulation of Gene_expression of Odc1 1 1 0.02 0 0.81
123 INT6409 Binding of NFKBIL1 and Oprm1 1 1 0.00 0 0.8
124 INT56501 Neurod1 Positive_regulation of Maoa Positive_regulation of Localization of Ide 1 1 0.41 0 0.8
125 INT56499 Neurod1 Positive_regulation of Maoa 1 1 0.47 0 0.8
126 INT90143 Negative_regulation of Binding of OPRL1 and OPRM1 1 1 0.31 0.07 0.8
127 INT6408 Binding of NFKBIL1 and Ap1m2 1 1 0.00 0 0.8
128 INT60102 Adora1 Regulation of Localization of Calca 1 1 0.46 0 0.79
129 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 1 0.38 0.39 0.76
130 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 1 0.18 0.39 0.76
131 INT90117 Jun Regulation of Gene_expression of Nos1 1 1 0.21 0.39 0.76
132 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 1 0.17 0.39 0.76
133 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 1 0.47 0.39 0.76
134 INT107028 KNG1 Regulation of Des 1 1 0.01 1.7 0.76
135 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 1 0.32 0.39 0.76
136 INT90122 Nfkb1 Positive_regulation of Gene_expression of Fos 1 1 0.39 0.39 0.75
137 INT24455 PDB1 Positive_regulation of Localization of NA 1 2 0.00 0 0.74
138 INT19577 Gabrg1 Negative_regulation of Got1 1 1 0.04 0.16 0.74
139 INT75399 Regulation of Binding of Dll1 and Oprd1 1 1 0.08 0 0.74
140 INT75398 Binding of Dll1 and Oprd1 1 1 0.11 0 0.74
141 INT133675 NPY6R Negative_regulation of SRC 1 1 0.17 0.75 0.74
142 INT61050 Oprd1 Positive_regulation of Odc1 1 1 0.25 0 0.74
143 INT136538 Nrgn Regulation of Car2 1 1 0.33 0 0.73
144 INT31243 Binding of Mme and Cpe 1 1 0.01 0 0.72
145 INT24967 Olr567 Regulation of Localization of Syt17 1 1 0.11 0.62 0.71
146 INT31417 Cocia8 Positive_regulation of Ins1 1 1 0.01 0 0.7
147 INT31415 Regulation of Cocia8 Positive_regulation of Ins1 1 1 0.00 0 0.7
148 INT89009 Lep Positive_regulation of Cck 2 1 0.67 0.43 0.69
149 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 1 0.16 0.43 0.69
150 INT74599 YY1 Negative_regulation of ADCY1 2 1 0.36 0.31 0.67
151 INT70998 IL1B Regulation of Gene_expression of Icam1 1 2 0.44 0.95 0.67
152 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 1 0.03 0 0.65
153 INT31418 Positive_regulation of Adra2c Positive_regulation of Gcg 1 1 0.22 0 0.65
154 INT90045 Oprd1 Positive_regulation of P9Ehs1 1 1 0.19 0.92 0.64
155 INT2700 Binding of App and Cpe 1 1 0.00 0 0.63
156 INT121460 KNG1 Positive_regulation of Bdkrb2 1 1 0.08 0.44 0.62
157 INT121459 Bdkrb2 Positive_regulation of KNG1 1 1 0.09 0.44 0.62
158 INT61826 Tnf Negative_regulation of Il1b 1 1 0.39 0.89 0.62
159 INT73402 Binding of Oprl1 and Wdyhv1 1 1 0.00 0 0.61
160 INT73403 Binding of Pdyn and Oprl1 1 1 0.01 0 0.61
161 INT121453 Bdkrb2 Positive_regulation of Trpv1 1 1 0.28 0.42 0.6
162 INT90119 Ntrk2 Regulation of Gene_expression of Nfkb1 1 1 0.01 0.27 0.6
163 INT133500 Calca Negative_regulation of Adarb1 1 1 0.02 0.26 0.59
164 INT123009 Oprm1 Positive_regulation of Localization of OR6K2 1 1 0.00 0 0.59
165 INT61827 Tnf Regulation of Lta 1 2 0.40 1.5 0.58
166 INT90115 Ntrk2 Regulation of Jun 1 1 0.01 0.27 0.57
167 INT98245 Binding of Oprm1 and Rbm39 1 1 0.01 0 0.57
168 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 1 0.36 0 0.57
169 INT76248 Tac1 Positive_regulation of Gene_expression of Fos 1 1 0.34 0.34 0.56
170 INT129271 Binding of ANTXR1 and Efs 1 1 0.00 0 0.56
171 INT116787 CALCRL Regulation of Trpv1 1 1 0.01 0 0.56
172 INT82869 Gast Positive_regulation of Localization of Cck 1 1 0.30 0 0.56
173 INT147273 Bdnf Regulation of Syp 1 1 0.24 0 0.56
174 INT59155 Binding of Adcyap1 and Vip 2 1 0.34 0.08 0.55
175 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 1 0.25 0 0.55
176 INT121993 Binding of EGF and SGCG 1 1 0.40 0 0.55
177 INT129269 Binding of Ts3 and Efs 1 1 0.01 0 0.55
178 INT82868 Cck Regulation of Pgc 1 1 0.05 0 0.55
179 INT147274 Bdnf Regulation of Gap43 1 1 0.37 0 0.55
180 INT129270 Binding of Wnt4 and Efs 1 1 0.00 0 0.55
181 INT61051 Pomc Negative_regulation of Odc1 1 1 0.22 0 0.54
182 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 1 0.05 0.16 0.54
183 INT29070 Binding of Isyna1 and LOC100360765 1 1 0.04 0 0.53
184 INT85559 Binding of Pnoc and Oprl1 1 1 0.39 0 0.53
185 INT29074 Binding of Isyna1 and AA2 1 1 0.03 0 0.53
186 INT22273 Nts Regulation of Oprl1 1 1 0.09 0 0.51
187 INT43075 Slc6a14 Regulation of Positive_regulation of Npr1 1 1 0.01 0 0.51
188 INT43076 Slc6a14 Regulation of Npr1 1 1 0.01 0 0.51
189 INT66188 Binding of ADRB2 and CDSN 1 2 0.01 0 0.51
190 INT85565 Oprd1 Regulation of KCNJ6 1 1 0.00 0 0.51
191 INT9169 Pomc Positive_regulation of Localization of Cck 1 1 0.29 0 0.5
192 INT90131 NOS1 Regulation of Fos 1 1 0.00 0.25 0.49
193 INT90121 Nos1 Regulation of Fos 1 1 0.27 0.25 0.49
194 INT135799 Binding of Adra1d and Adra2b 1 1 0.02 0 0.48
195 INT110031 Positive_regulation of Adra2c Positive_regulation of Mapk14 1 1 0.25 0 0.48
196 INT55020 Gh1 Regulation of Gene_expression of Prl 1 1 0.19 0 0.48
197 INT110030 Adra2c Positive_regulation of Mapk14 1 1 0.25 0 0.48
198 INT83690 Binding of Oprm1 and Ptprg 1 1 0.00 0.08 0.48
199 INT110034 Negative_regulation of Adra2c Positive_regulation of Mapk14 1 1 0.23 0 0.48
200 INT123715 Binding of Cnr2 and oh 1 1 0.02 0.3 0.47

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT158 Localization of Prl 40 2431 0.81 378.96 952.2
2 INT6483 Gene_expression of TNF 13 3152 0.78 2515.62 929.82
3 INT3439 Localization of Abat 41 1017 0.78 112.39 727.06
4 INT58061 Gene_expression of Trpv1 17 1117 0.78 451.54 637.59
5 INT797 Regulation of Penk 9 812 0.62 111.13 542.24
6 INT5228 Positive_regulation of Fos 37 934 0.70 209.8 503.87
7 INT155 Positive_regulation of Prl 18 1233 0.70 317.93 457.82
8 INT1045 Localization of LH 15 1211 0.81 87.04 456.25
9 INT443 Localization of POMC 6 1020 0.81 284.52 443.17
10 INT5895 Gene_expression of Oprm1 13 525 0.78 120.67 407.29
11 INT64202 Positive_regulation of Trpv1 6 643 0.70 249.66 397.42
12 INT467 Gene_expression of POMC 4 1048 0.78 332.8 394.16
13 INT2540 Negative_regulation of Calca 17 538 0.59 172.11 384.38
14 INT157 Positive_regulation of Localization of Prl 14 790 0.70 104.54 374.78
15 INT287 Localization of Cck 18 518 0.81 86.84 364.04
16 INT439 Localization of Gnrh1 4 976 0.81 100.96 363.25
17 INT720 Positive_regulation of POMC 5 807 0.70 237.37 353.83
18 INT5660 Binding of Oprd1 26 477 0.48 71.86 342.06
19 INT876 Localization of Gh1 11 843 0.80 67.75 340.82
20 INT16260 Gene_expression of Bdnf 4 671 0.78 283.44 339.1
21 INT5235 Negative_regulation of TNF 4 924 0.59 772.91 331.98
22 INT162 Regulation of Prl 22 794 0.62 165.01 322.24
23 INT5979 Gene_expression of Oprd1 14 428 0.78 75.64 320.32
24 INT34869 Negative_regulation of PTGS2 15 778 0.59 366.76 319.85
25 INT5540 Positive_regulation of Oprm1 21 344 0.70 76.77 319.71
26 INT46460 Gene_expression of NAV1 3 288 0.78 135.51 305.75
27 INT4941 Positive_regulation of Oprd1 20 345 0.70 74.26 304.41
28 INT9131 Positive_regulation of Prkcg 7 431 0.70 130.8 302.41
29 INT477 Localization of Avp 28 813 0.81 131.58 300.4
30 INT161 Regulation of Localization of Prl 16 615 0.62 65.37 298.66
31 INT63932 Positive_regulation of Ephb1 1 537 0.70 259.67 296.14
32 INT1352 Localization of Acot1 13 728 0.80 73.01 296.01
33 INT886 Gene_expression of Pomc 17 676 0.78 129.87 295.98
34 INT11624 Gene_expression of OPRM1 5 445 0.78 72.36 294.36
35 INT5379 Gene_expression of Fos 1 656 0.78 255.5 292.54
36 INT3579 Localization of Oxt 11 555 0.81 43.35 292.44
37 INT2365 Positive_regulation of Cck 12 354 0.70 87.8 277.41
38 INT6852 Localization of TNF 5 883 0.81 705.95 270.84
39 INT1396 Binding of Penk 12 355 0.48 22.79 269.65
40 INT9659 Gene_expression of Il6 1 991 0.78 715.11 265.57
41 INT5972 Gene_expression of IL1B 4 948 0.78 510.91 263.97
42 INT68684 Gene_expression of VEGFA 3 2371 0.78 1742.52 259.2
43 INT87687 Positive_regulation of Trpv1 1 409 0.70 210.24 257.59
44 INT16868 Gene_expression of Il6 5 807 0.78 499.48 256.57
45 INT2909 Positive_regulation of Abat 13 334 0.70 62.1 256.43
46 INT3948 Regulation of Cck 15 291 0.62 58.07 255.88
47 INT5501 Regulation of Oprd1 22 283 0.62 55.1 249.9
48 INT1005 Localization of Sst 11 385 0.81 26.31 244.56
49 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
50 INT1902 Gene_expression of Cck 6 348 0.78 70.33 241.92
51 INT1562 Localization of Crh 6 499 0.81 126.74 236.68
52 INT5597 Gene_expression of Pdyn 10 433 0.78 62.97 235.47
53 INT9987 Gene_expression of Abat 1 296 0.78 95.46 226.34
54 INT6406 Binding of Oprm1 9 280 0.48 40.54 226.26
55 INT1212 Binding of Oprl1 24 312 0.48 28.6 225.15
56 INT626 Localization of CALCA 4 289 0.81 125.39 221.15
57 INT6665 Gene_expression of FOS 4 520 0.77 165.31 217.66
58 INT1308 Localization of Pomc 9 457 0.81 66.83 217.5
59 INT767 Localization of Gnrhr 7 565 0.80 106.68 214.57
60 INT4893 Gene_expression of Tacr1 1 366 0.78 129.67 213.92
61 INT6482 Positive_regulation of Gene_expression of TNF 6 659 0.70 569.88 210
62 INT48955 Gene_expression of Nos2 9 753 0.78 403.87 208.08
63 INT2651 Positive_regulation of Pomc 8 403 0.70 95.72 206.24
64 INT9132 Negative_regulation of Prkcg 5 279 0.59 88.05 203.47
65 INT798 Positive_regulation of Gene_expression of Penk 1 394 0.70 78.53 203.07
66 INT11313 Positive_regulation of Il6 3 526 0.70 331.27 201.59
67 INT2211 Negative_regulation of Abat 5 267 0.59 66.51 200.98
68 INT156 Negative_regulation of Prl 15 542 0.59 131.97 192.24
69 INT528 Gene_expression of Prl 11 693 0.78 217.18 192.2
70 INT6354 Localization of Gabrg1 3 321 0.74 41.41 186.74
71 INT1652 Regulation of Pomc 15 387 0.62 61.01 186.51
72 INT4803 Transcription of Penk 3 435 0.72 59.09 182.4
73 INT3440 Negative_regulation of Localization of Abat 7 221 0.57 33.94 180.36
74 INT12602 Negative_regulation of Oprm1 15 190 0.59 36.11 177.85
75 INT49441 Negative_regulation of Cpox 4 494 0.59 303.22 177.46
76 INT1429 Gene_expression of PDYN 2 308 0.78 61.33 175.65
77 INT943 Negative_regulation of Cck 9 205 0.59 38.42 174.78
78 INT26472 Regulation of Oprm1 19 191 0.62 35.84 173.1
79 INT159 Negative_regulation of Localization of Prl 15 416 0.59 55.34 171.8
80 INT4937 Negative_regulation of Oprd1 15 224 0.59 44.51 171.11
81 INT438 Gene_expression of Crh 6 376 0.78 159.11 169.17
82 INT867 Gene_expression of IFNA1 1 930 0.78 594.85 168.03
83 INT739 Negative_regulation of POMC 2 358 0.59 102.28 166.77
84 INT4768 Positive_regulation of OPRM1 4 212 0.70 31.09 164.28
85 INT2366 Binding of Cck 2 192 0.48 30.64 163.46
86 INT5513 Negative_regulation of Pomc 9 295 0.59 60.9 158.63
87 INT51921 Gene_expression of Cpox 17 501 0.73 229.81 157.81
88 INT21185 Binding of Ptprg 15 213 0.47 13.49 157.75
89 INT1303 Negative_regulation of Npr1 28 278 0.55 35.1 156.78
90 INT2640 Gene_expression of Pomc 12 424 0.78 120.72 155.37
91 INT6042 Binding of Oprm1 9 248 0.48 31.77 154.34
92 INT4740 Gene_expression of Th 3 298 0.78 61.27 154.03
93 INT2910 Regulation of Abat 6 169 0.62 36.95 153.53
94 INT1044 Negative_regulation of Localization of LH 8 358 0.59 25.95 151.31
95 INT4829 Positive_regulation of Localization of Abat 12 199 0.55 20.91 150.48
96 INT880 Positive_regulation of Localization of Gh1 8 304 0.70 14.79 150.23
97 INT49134 Gene_expression of Grin1 2 270 0.78 84.78 148.61
98 INT5050 Regulation of Localization of Calca 9 149 0.62 41.25 148.57
99 INT6108 Gene_expression of Npy 2 292 0.78 110.65 148.21
100 INT2451 Positive_regulation of Avp 4 355 0.70 102.66 147.69
101 INT1033 Positive_regulation of Ca2 14 507 0.68 131.76 147.64
102 INT9852 Positive_regulation of Gpt 1 563 0.70 364.64 146.82
103 INT9852 Positive_regulation of Gpt 2 563 0.70 364.64 146.82
104 INT812 Localization of INS 4 1026 0.81 515.6 145.31
105 INT425 Localization of PRL 6 455 0.81 189.64 144.8
106 INT2379 Positive_regulation of Localization of LH 9 349 0.70 27.86 144.53
107 INT2780 Regulation of Gene_expression of Penk 2 265 0.62 32.45 143.88
108 INT1414 Regulation of Oprl1 24 169 0.62 32.05 139.99
109 INT14843 Gene_expression of Gabrg1 1 301 0.77 62.63 139.16
110 INT1273 Gene_expression of Avp 4 356 0.78 90.56 138.7
111 INT48895 Gene_expression of Il10 2 333 0.78 221.2 138.52
112 INT2867 Gene_expression of CALCA 4 247 0.78 78.78 138.47
113 INT5061 Negative_regulation of Mme 25 306 0.59 51.97 136.9
114 INT4658 Binding of OPRM1 6 188 0.48 25.96 136.24
115 INT2541 Binding of Calca 8 200 0.48 67.14 134.62
116 INT48953 Positive_regulation of Nos2 8 486 0.70 239.85 131.87
117 INT5497 Positive_regulation of Crh 14 299 0.70 125.54 131.14
118 INT49439 Gene_expression of Cpox 8 508 0.73 326.97 130.17
119 INT5931 Regulation of Oprm1 8 149 0.62 18.15 125.93
120 INT6822 Gene_expression of Pdyn 3 215 0.78 35.99 125.76
121 INT416 Regulation of LH 4 253 0.62 31.48 125.55
122 INT6323 Positive_regulation of Gabrg1 2 213 0.70 45.08 124.34
123 INT4824 Positive_regulation of Tacr1 2 169 0.70 66.1 123.46
124 INT4259 Positive_regulation of Npr1 19 262 0.70 49.37 123.11
125 INT2106 Regulation of Localization of LH 3 279 0.62 22.37 122.77
126 INT252 Localization of GH1 4 529 0.80 227.4 122.05
127 INT6128 Positive_regulation of Localization of POMC 1 256 0.70 68.77 121.64
128 INT14151 Gene_expression of Casp3 8 311 0.78 140.26 120.68
129 INT218 Positive_regulation of Th 9 245 0.70 40.5 120.1
130 INT64201 Negative_regulation of Trpv1 6 203 0.59 79.18 119.75
131 INT2555 Positive_regulation of Localization of Penk 3 116 0.70 24.35 119.73
132 INT12501 Positive_regulation of Adarb1 12 166 0.58 36.94 118.92
133 INT9235 Negative_regulation of Gene_expression of TNF 3 346 0.59 252.98 118.61
134 INT50674 Gene_expression of PTGS2 9 459 0.78 253.33 118.51
135 INT7341 Positive_regulation of Grin1 1 169 0.70 65.86 118.38
136 INT12339 Localization of IL8 6 437 0.81 251.87 117.39
137 INT1438 Localization of Pomc 6 360 0.81 101.26 116.47
138 INT4207 Regulation of Avp 11 267 0.62 63.72 115.33
139 INT48593 Positive_regulation of NOS1 1 420 0.68 226.15 114.71
140 INT16253 Positive_regulation of Gene_expression of Bdnf 2 196 0.70 92.67 113.01
141 INT90 Localization of Gast 4 400 0.81 137.67 113
142 INT7362 Gene_expression of Sst 1 185 0.78 41.73 111.37
143 INT7327 Regulation of Th 2 164 0.62 29.67 110.14
144 INT65731 Gene_expression of Cnr1 2 234 0.78 63.82 109.34
145 INT8413 Gene_expression of Ptgs1 8 248 0.78 110.17 108.58
146 INT47243 Gene_expression of Prkcg 5 195 0.78 58.05 108.44
147 INT4936 Localization of Tacr1 9 125 0.80 35.7 107.7
148 INT3038 Gene_expression of INS 1 1583 0.78 1174.16 107.01
149 INT7627 Negative_regulation of Positive_regulation of Ltp 2 162 0.50 41.2 106.27
150 INT9012 Localization of Vip 5 283 0.81 31.71 106.16
151 INT12082 Localization of IL6 3 365 0.81 241.78 105.78
152 INT12569 Localization of Oprd1 7 94 0.81 23.81 104.56
153 INT915 Positive_regulation of PRL 1 342 0.70 141.96 104.31
154 INT114 Binding of Oprl1 3 139 0.48 23 103.35
155 INT10272 Gene_expression of Il1b 14 194 0.78 121.02 103.03
156 INT4742 Gene_expression of Tac1 2 177 0.78 69.99 102.66
157 INT1898 Regulation of Crh 14 220 0.62 61.33 102.64
158 INT89054 Positive_regulation of Gene_expression of Trpv1 4 156 0.70 90.78 102.03
159 INT10838 Positive_regulation of IL8 1 381 0.70 295.51 101.62
160 INT5906 Negative_regulation of Oprm1 11 125 0.59 19.58 101.57
161 INT5940 Negative_regulation of Avp 9 236 0.59 67.86 101.2
162 INT397 Localization of SST 2 232 0.81 58.05 101.19
163 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
164 INT74826 Gene_expression of Slc1a2 1 131 0.78 61.83 100.84
165 INT97701 Phosphorylation of Mapk14 1 191 0.82 115.33 100.46
166 INT5587 Regulation of Fos 5 191 0.62 40.81 99.7
167 INT52651 Positive_regulation of Prkaca 2 136 0.67 40.82 99.16
168 INT2159 Regulation of Localization of Gnrh1 1 200 0.62 13.28 99.07
169 INT7944 Positive_regulation of Fos 4 193 0.70 60.69 98.31
170 INT874 Positive_regulation of Gh1 5 244 0.70 27.17 97.98
171 INT4822 Localization of Ca2 5 417 0.80 99.57 96.45
172 INT1760 Gene_expression of PTGER2 2 524 0.57 226.94 96.4
173 INT1004 Regulation of Sst 1 140 0.62 18.52 94.84
174 INT2862 Positive_regulation of Localization of Cck 5 108 0.70 20.75 94.25
175 INT29971 Gene_expression of Oprk1 6 126 0.78 35.32 93.97
176 INT203 Positive_regulation of Pomc 5 257 0.70 90.56 92.84
177 INT2122 Negative_regulation of Localization of Gnrh1 1 226 0.59 26.92 92.04
178 INT1281 Negative_regulation of Maoa 21 203 0.59 22.47 91.66
179 INT94953 Negative_regulation of Mapk14 4 156 0.59 104.77 91.51
180 INT69764 Positive_regulation of Cnr1 1 126 0.70 67.8 91.49
181 INT9516 Negative_regulation of Gabrg1 2 149 0.53 27.83 91.02
182 INT38731 Localization of Trpv1 3 138 0.81 52.73 90.49
183 INT6437 Binding of YY1 6 154 0.47 26.3 90.46
184 INT1639 Negative_regulation of OPRM1 6 107 0.59 13.86 90.37
185 INT1160 Positive_regulation of Rbm39 11 122 0.57 28.19 90.28
186 INT6585 Positive_regulation of Insrr 10 110 0.52 40.67 89.9
187 INT18032 Positive_regulation of Oprk1 2 108 0.70 30.78 89.7
188 INT6214 Negative_regulation of Adarb1 4 123 0.50 26.39 89.57
189 INT71789 Positive_regulation of MAPK1 4 396 0.70 234.44 89.27
190 INT96917 Positive_regulation of Mapk14 3 261 0.70 173.29 88.79
191 INT64158 Negative_regulation of Prkca 1 121 0.59 29.8 88.66
192 INT1635 Gene_expression of Vip 6 245 0.78 53.36 88.13
193 INT7180 Negative_regulation of Trib3 10 180 0.51 68.48 88.01
194 INT7885 Positive_regulation of Localization of Oxt 1 160 0.70 14.36 87.7
195 INT3441 Regulation of Localization of Abat 9 117 0.38 8.67 87.59
196 INT54571 Positive_regulation of NFKB1 2 263 0.70 138.99 87.32
197 INT5594 Regulation of Pdyn 4 137 0.62 27.04 86.63
198 INT1472 Positive_regulation of Ins1 11 349 0.69 146.2 86.36
199 INT5610 Positive_regulation of Insr 1 140 0.69 37.26 86.24
200 INT4798 Gene_expression of Nts 4 169 0.77 29.56 86.04
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