J:Eur J Clin Pharmacol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT266811 Binding of HRH1 and HTR2C 1 3 0.23 2.06 1.4
2 INT223283 Binding of CYP2C9 and VKORC1 1 1 0.31 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT812 Localization of INS 4 1026 0.81 515.6 145.31
2 INT90091 Gene_expression of GOPC 1 967 0.67 366.22 103.6
3 INT15913 Negative_regulation of CYP2D6 1 174 0.59 22.45 70.91
4 INT822 Gene_expression of ESR1 3 529 0.78 302.16 63.64
5 INT1199 Positive_regulation of INS 1 579 0.70 399.64 50.43
6 INT7093 Negative_regulation of CYP2B6 2 146 0.58 37.3 48.39
7 INT3252 Negative_regulation of INS 1 428 0.59 271.65 39.52
8 INT9082 Positive_regulation of ESR1 1 238 0.69 148.51 36.69
9 INT3253 Negative_regulation of Localization of INS 3 205 0.59 130.39 36.61
10 INT10796 Gene_expression of CYP2B6 2 131 0.77 30.14 35.27
11 INT15610 Localization of GOPC 1 223 0.65 68.26 28.7
12 INT12129 Gene_expression of CYP3A4 2 107 0.78 23.11 27.6
13 INT2040 Positive_regulation of CYP2B6 1 95 0.69 34.3 25.6
14 INT82434 Positive_regulation of LEP 1 117 0.70 95.45 20.22
15 INT20631 Positive_regulation of CHKB 3 166 0.69 109.86 17.92
16 INT13510 Gene_expression of ERBB2 2 530 0.78 405.68 16.79
17 INT1020 Negative_regulation of BCHE 1 109 0.59 44.86 16.4
18 INT62681 Negative_regulation of LEP 1 93 0.59 66.97 15.77
19 INT51028 Regulation of Il1b 1 28 0.60 21.15 12.47
20 INT16772 Gene_expression of MPO 1 81 0.78 90.98 11.9
21 INT10798 Positive_regulation of CYP2D6 1 24 0.56 5.82 11.31
22 INT22210 Gene_expression of CYP1A2 2 45 0.78 4.95 10.66
23 INT61171 Gene_expression of S100A8 1 92 0.76 57.74 9.98
24 INT9548 Gene_expression of CHKB 1 99 0.65 50.86 9.03
25 INT13467 Positive_regulation of ABCB1 2 36 0.68 9.68 8.95
26 INT13467 Positive_regulation of ABCB1 1 36 0.68 9.68 8.95
27 INT82839 Negative_regulation of ABCB1 1 61 0.59 16.09 8.83
28 INT44378 Gene_expression of GSTM1 1 69 0.76 34.61 8.81
29 INT66819 Binding of CYP2C9 1 41 0.48 8.23 8.76
30 INT2271 Gene_expression of F2 2 51 0.76 30.21 7.97
31 INT15687 Regulation of ESR1 2 91 0.60 40.42 7.95
32 INT11823 Positive_regulation of GGT1 2 53 0.67 45.84 7.55
33 INT7883 Binding of ADRB2 1 18 0.47 5.49 7.37
34 INT110987 Transcription of ESR1 3 45 0.71 24.16 6.72
35 INT2039 Regulation of CYP2B6 2 30 0.60 7.75 6.43
36 INT69561 Positive_regulation of GSTM1 1 23 0.50 5.69 6.36
37 INT11826 Positive_regulation of LDLR 1 62 0.62 45.09 6.21
38 INT64888 Negative_regulation of HBM 2 52 0.16 34.33 5.45
39 INT18772 Positive_regulation of Gene_expression of CYP2B6 2 14 0.49 2.93 5.4
40 INT78914 Positive_regulation of ABCC1 1 19 0.67 7.99 5.18
41 INT40638 Binding of HRH1 4 14 0.44 5.81 5.09
42 INT49748 Binding of HTR2C 2 10 0.47 3.03 4.76
43 INT119063 Gene_expression of BRCA1 1 24 0.67 30.04 4.17
44 INT9854 Localization of GGT1 1 11 0.78 6.09 3.57
45 INT57728 Regulation of LDLR 1 25 0.41 13.18 3.46
46 INT15299 Gene_expression of IL1RL1 1 37 0.69 10.09 3.43
47 INT120515 Gene_expression of Otc 1 13 0.66 4.33 2.6
48 INT39518 Negative_regulation of HBN1 2 66 0.09 37.54 2.58
49 INT101 Negative_regulation of HRH1 1 8 0.57 3.48 2.55
50 INT62653 Positive_regulation of CYP2C19 1 8 0.54 1.23 2.41
51 INT93009 Regulation of HBN1 1 24 0.17 17.6 2.03
52 INT20630 Positive_regulation of Gene_expression of CHKB 1 19 0.47 15.79 1.85
53 INT48792 Regulation of ERBB2 2 48 0.57 36.56 1.8
54 INT180185 Gene_expression of MGMT 1 22 0.65 15.02 1.57
55 INT230 Positive_regulation of GGTLC1 1 14 0.68 11.78 1.55
56 INT106261 Negative_regulation of DPYD 3 16 0.59 15.02 1.19
57 INT82703 Transcription of LDLR 1 6 0.64 0.4 1.13
58 INT94690 Gene_expression of DPYD 4 12 0.75 4.6 1.07
59 INT71906 Regulation of Gene_expression of ESR1 1 22 0.41 11.01 0.98
60 INT12555 Binding of ADRB1 1 7 0.39 3.78 0.97
61 INT154468 Negative_regulation of Transcription of ESR1 1 3 0.29 1.14 0.96
62 INT62702 Negative_regulation of HTR2C 1 2 0.42 1.14 0.75
63 INT266816 Localization of HBN1 1 2 0.22 2.49 0.56
64 INT28097 Negative_regulation of Wbc1 2 8 0.11 4.07 0.53
65 INT112287 Gene_expression of SLCO1B1 1 3 0.75 0.09 0.32
66 INT121072 Gene_expression of NMUR2 2 3 0.27 0.81 0.26
67 INT20616 Localization of F2 1 5 0.68 1.61 0.19
68 INT246628 Binding of CNNM3 1 2 0.03 0.69 0.18
69 INT85595 Positive_regulation of CYP2A6 1 5 0.67 1.02 0.17
70 INT181787 Transcription of ERBB2 2 13 0.71 10.03 0.16
71 INT266813 Negative_regulation of CNNM3 1 1 0.03 0.78 0.14
72 INT183206 Regulation of UTS2R 1 5 0.13 3.17 0.12
73 INT235892 Gene_expression of Cby1 1 1 0.65 0 0.08
74 INT235898 Positive_regulation of NR1H3 2 1 0.36 0 0.05
75 INT235896 Regulation of NMUR2 3 1 0.18 0 0.03
76 INT202203 Positive_regulation of GSTT1 1 4 0.47 1.26 0
77 INT203873 Phosphorylation of NAT2 1 2 0.81 0.69 0
78 INT174724 Regulation of Transcription of ESR1 1 2 0.18 0.49 0
79 INT152578 Positive_regulation of MROS 1 1 0.02 0 0
80 INT235893 Negative_regulation of Cby1 3 1 0.42 0.42 0
81 INT223288 Protein_catabolism of DPYD 1 1 0.46 0.11 0
82 INT223289 Negative_regulation of H6PD 4 1 0.24 0.55 0
83 INT155651 Localization of GGTLC1 1 1 0.16 0.08 0
84 INT223290 Binding of VKORC1 1 1 0.39 0.16 0
85 INT223291 Regulation of Transcription of ERBB2 1 1 0.25 0.21 0
86 INT223292 Localization of SLC22A3 1 1 0.29 0.06 0
87 INT223293 Localization of SLC22A1 1 1 0.30 0.06 0
88 INT223294 Localization of POU2F2 1 1 0.33 0.06 0
89 INT235897 Binding of NMUR2 1 1 0.14 0.24 0
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