J:Eur Spine J

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT114754 Il6 Positive_regulation of Gene_expression of Crp 2 1 0.08 1.67 0.47
2 INT114755 Il6 Positive_regulation of Crp 1 1 0.08 0.41 0.35
3 INT123221 Binding of ADRA1D and TNFAIP6 1 1 0.03 0.76 0.25

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 2 3152 0.78 2515.62 929.82
2 INT2649 Regulation of Calca 2 433 0.62 146.05 330.95
3 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
4 INT6852 Localization of TNF 4 883 0.81 705.95 270.84
5 INT9659 Gene_expression of Il6 1 991 0.78 715.11 265.57
6 INT68684 Gene_expression of VEGFA 2 2371 0.78 1742.52 259.2
7 INT16868 Gene_expression of Il6 2 807 0.78 499.48 256.57
8 INT6481 Binding of TNF 1 624 0.48 510.2 214.82
9 INT11313 Positive_regulation of Il6 1 526 0.70 331.27 201.59
10 INT10194 Positive_regulation of IL6 2 702 0.70 600.62 183.38
11 INT13353 Positive_regulation of Tnf 2 332 0.70 248.75 148.1
12 INT9660 Regulation of TNF 3 363 0.62 312.94 139.99
13 INT2541 Binding of Calca 1 200 0.48 67.14 134.62
14 INT11051 Positive_regulation of Gene_expression of IL6 1 415 0.69 319.21 109.3
15 INT10272 Gene_expression of Il1b 1 194 0.78 121.02 103.03
16 INT10838 Positive_regulation of IL8 6 381 0.70 295.51 101.62
17 INT11381 Positive_regulation of IL1B 2 330 0.70 209.31 100.9
18 INT68682 Positive_regulation of VEGFA 2 640 0.70 454.14 81.65
19 INT5056 Gene_expression of IFNG 1 216 0.78 137.52 74.57
20 INT10274 Positive_regulation of Il1b 1 123 0.70 79.76 73.56
21 INT19511 Localization of Il6 5 212 0.81 118.17 67.67
22 INT4960 Positive_regulation of CSF2 2 285 0.70 256.73 65.73
23 INT10706 Regulation of Il6 3 150 0.62 93.23 62.34
24 INT5058 Positive_regulation of IFNA1 1 356 0.70 245.75 60.52
25 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
26 INT5356 Positive_regulation of FOS 1 153 0.69 54.21 56.74
27 INT9210 Regulation of IL6 2 166 0.62 125.61 49.95
28 INT26500 Gene_expression of MMP2 7 201 0.78 110.57 46.9
29 INT5307 Regulation of Tnf 1 87 0.62 78.71 43.4
30 INT613 Gene_expression of Alb 1 268 0.78 149.84 42.78
31 INT29496 Gene_expression of MMP3 2 136 0.75 49.49 41.78
32 INT5973 Regulation of IL1B 1 109 0.62 66.6 39.88
33 INT6484 Binding of IL1B 1 122 0.47 75.84 35.07
34 INT16960 Gene_expression of Crp 1 166 0.76 116.21 34.07
35 INT9347 Localization of Il1b 4 58 0.81 26.13 31.53
36 INT48693 Regulation of VEGFA 1 268 0.62 191.88 31.52
37 INT10285 Binding of ADRA1D 1 102 0.47 25.82 31.11
38 INT48202 Gene_expression of Tgfb1 1 146 0.78 89.93 27.76
39 INT55737 Positive_regulation of MMP2 3 101 0.68 59.11 27.71
40 INT17331 Positive_regulation of JUN 2 132 0.69 60.4 27.03
41 INT78251 Positive_regulation of LBP 1 38 0.69 39.98 26.73
42 INT9088 Negative_regulation of LBP 1 48 0.58 33.06 25.89
43 INT5948 Regulation of Il1b 4 44 0.60 22.8 25.4
44 INT10835 Regulation of IL8 1 79 0.49 53.04 24.14
45 INT51474 Binding of Il6 1 55 0.48 44.99 20.52
46 INT48144 Gene_expression of Fgf2 1 117 0.78 43 20.48
47 INT50814 Positive_regulation of Mmp2 2 72 0.68 51.37 20.42
48 INT68683 Regulation of Gene_expression of VEGFA 1 143 0.62 104.19 20.14
49 INT68681 Transcription of VEGFA 1 132 0.71 80.47 17.03
50 INT26314 Positive_regulation of MMP3 1 48 0.67 22.14 16.17
51 INT22909 Positive_regulation of Chdh 2 26 0.68 28.69 16.13
52 INT26501 Positive_regulation of Gene_expression of MMP2 4 51 0.67 39 15.16
53 INT55256 Negative_regulation of Localization of Il6 2 38 0.58 16.12 13.67
54 INT36263 Positive_regulation of CEL 1 53 0.69 34.88 12.87
55 INT7125 Gene_expression of PLA2G2A 2 47 0.78 42.12 7.83
56 INT75497 Regulation of JUN 1 28 0.61 11.04 7.09
57 INT108628 Regulation of MMP2 2 27 0.60 14.85 6.06
58 INT15803 Regulation of IFNG 1 21 0.44 12.57 5.98
59 INT10705 Binding of Il1b 1 9 0.36 2.8 5.53
60 INT62570 Binding of Pth 1 48 0.48 26.45 4.85
61 INT18011 Positive_regulation of HP 1 60 0.50 31.88 4.75
62 INT102237 Positive_regulation of Gene_expression of MMP3 2 22 0.44 7.77 4.71
63 INT64864 Gene_expression of PLA2G4A 2 18 0.77 10.45 4.09
64 INT27455 Positive_regulation of C2 1 18 0.60 4.3 3.93
65 INT90406 Gene_expression of IL6R 2 27 0.38 15.74 3.64
66 INT101441 Positive_regulation of FTH1 1 15 0.54 7.03 3.22
67 INT101083 Binding of Fgf2 1 14 0.42 4.12 3.14
68 INT106468 Regulation of Gene_expression of MMP2 2 11 0.50 3.53 2.77
69 INT114753 Negative_regulation of Gene_expression of Crp 1 7 0.42 4.79 2.77
70 INT67275 Gene_expression of L2 2 6 0.66 1.9 2.63
71 INT46332 Binding of Mmp2 1 10 0.34 5.63 2
72 INT78773 Regulation of PLA2G2A 1 11 0.61 9.76 1.91
73 INT2519 Negative_regulation of VCF 1 7 0.43 5.27 1.79
74 INT123223 Binding of TNFAIP6 2 5 0.35 3.36 1.65
75 INT78774 Gene_expression of PLA2G6 1 15 0.61 8.39 1.56
76 INT123224 Gene_expression of TNFAIP6 4 12 0.70 7.13 1.21
77 INT110075 Binding of FTH1 1 10 0.36 1.12 1.13
78 INT110322 Positive_regulation of MORF4 1 1 0.49 1.65 0.98
79 INT48577 Gene_expression of Capn3 1 3 0.67 0.61 0.97
80 INT110076 Regulation of C6 1 2 0.22 1.14 0.96
81 INT124884 Gene_expression of Rpl4 1 3 0.53 1.56 0.9
82 INT124885 Gene_expression of Insrr 1 1 0.05 0.65 0.77
83 INT102311 Regulation of IL6R 1 4 0.12 2.37 0.74
84 INT62421 Gene_expression of Trpc2 2 8 0.68 5.48 0.67
85 INT78775 Regulation of PLA2G4A 1 4 0.25 1.45 0.55
86 INT108629 Negative_regulation of Regulation of MMP2 2 1 0.41 0.7 0.52
87 INT111008 Transcription of ITPA 1 1 0.67 0.55 0.39
88 INT90405 Positive_regulation of Gene_expression of IL6R 1 3 0.03 1.85 0.31
89 INT97908 Binding of Col9a2 1 3 0.18 2.51 0.29
90 INT123222 Binding of ITIH1 1 1 0.13 0.75 0.25
91 INT115363 Positive_regulation of MAP6 1 1 0.49 0.4 0.2
92 INT50013 Regulation of C2CD4A 1 1 0.39 0.53 0.16
93 INT129776 Binding of Col9a3 1 1 0.18 0.68 0.13
94 INT129774 Binding of Trpc2 1 2 0.18 0.73 0.12
95 INT129778 Gene_expression of Col9a3 1 1 0.33 0.76 0.12
96 INT129775 Gene_expression of Col9a2 1 1 0.11 0.76 0.12
97 INT128091 Binding of TGFBR2 1 1 0.02 0.08 0.08
98 INT126373 Binding of FRI 1 1 0.31 0.07 0.07
99 INT129777 Regulation of Col9a3 1 1 0.22 0.46 0.03
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