J:Expert Reviews in Molecular Medicine

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT253759 Hmgb1 Positive_regulation of Apex1 1 3 0.09 4.53 0.69
2 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 5 0.10 3.53 0.58
3 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 1 0.16 1.18 0.54
4 INT253767 Binding of Hmgb1 and Tlr9 2 1 0.12 1.78 0.52
5 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 1 0.08 0.71 0.49
6 INT253766 Binding of Apex1 and Tlr4 1 1 0.03 0.53 0.32
7 INT253762 Binding of Apex1 and Hmgb1 1 1 0.09 1.29 0.32
8 INT253765 Apex1 Positive_regulation of Hmgb1 1 1 0.09 1.27 0.24
9 INT253771 Gopc Positive_regulation of Hmgb1 1 1 0.03 1.27 0.24
10 INT253773 TNF Positive_regulation of Hmgb1 1 1 0.09 1.21 0.23
11 INT253776 Binding of THBD and F2 1 2 0.00 1.15 0.18
12 INT253761 Hmgb1 Positive_regulation of Gene_expression of Gopc 1 1 0.03 0.73 0.12
13 INT253772 Binding of THBD and Hmgb1 1 2 0.05 0.95 0.12
14 INT253775 Negative_regulation of Binding of THBD and Hmgb1 1 1 0.06 0.69 0.12
15 INT253774 THBD Regulation of F2 1 1 0.00 0.61 0.08
16 INT253764 Atp9a Positive_regulation of Apex1 1 1 0.00 0.39 0.08
17 INT253769 Binding of Hmgb1 and Il1 1 1 0.01 0.27 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
3 INT6852 Localization of TNF 4 883 0.81 705.95 270.84
4 INT10832 Gene_expression of IL8 1 1050 0.78 698.72 270
5 INT9659 Gene_expression of Il6 2 991 0.78 715.11 265.57
6 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
7 INT6482 Positive_regulation of Gene_expression of TNF 1 659 0.70 569.88 210
8 INT120811 Gene_expression of Gopc 1 1174 0.59 428.49 150.55
9 INT1878 Binding of HLA-B 2 440 0.48 321.16 127.36
10 INT75999 Gene_expression of BDNF 1 344 0.78 114.19 83.12
11 INT749 Gene_expression of HLA-B 1 341 0.75 224.12 77.37
12 INT10837 Positive_regulation of Gene_expression of IL8 1 294 0.70 190.08 70.34
13 INT11937 Localization of Il6 2 228 0.81 139.83 64.39
14 INT9657 Positive_regulation of Gene_expression of Il6 1 237 0.70 180.45 63.6
15 INT19775 Localization of Il1 2 183 0.78 145.5 50.91
16 INT2732 Gene_expression of VIP 3 74 0.78 24.57 33.72
17 INT114362 Localization of Hmgb1 28 127 0.78 120.28 23.26
18 INT15148 Gene_expression of Vip 3 51 0.77 25.61 18.33
19 INT25517 Regulation of NFKB1 1 41 0.61 22.28 16.09
20 INT9220 Gene_expression of Ighg1 1 125 0.77 85.74 15.92
21 INT49376 Negative_regulation of Localization of Il6 1 37 0.59 12.66 14.99
22 INT11699 Binding of HLA-E 1 85 0.47 52.51 13.41
23 INT20376 Gene_expression of Ccl3 1 39 0.75 45.42 13.15
24 INT39553 Gene_expression of Hmgb1 7 50 0.75 51.18 12.21
25 INT155808 Gene_expression of Ccl4 1 24 0.65 21.36 9.18
26 INT114363 Positive_regulation of Hmgb1 11 50 0.67 48.92 8.15
27 INT62400 Positive_regulation of Localization of Il1 1 34 0.67 35.53 7.96
28 INT212758 Binding of Hmgb1 14 40 0.44 35.6 7.41
29 INT53572 Negative_regulation of Localization of Il1 1 18 0.40 12.78 6.7
30 INT190520 Negative_regulation of Hmgb1 6 24 0.53 20.08 5.6
31 INT131808 Localization of Apex1 14 2 0.16 13.46 4.61
32 INT215071 Positive_regulation of Localization of Hmgb1 9 34 0.63 22.03 4.15
33 INT215085 Positive_regulation of Gene_expression of Hmgb1 4 17 0.63 16.81 4.13
34 INT215074 Negative_regulation of Localization of Hmgb1 7 28 0.57 15.09 4
35 INT144083 Positive_regulation of Gene_expression of Ccl3 1 10 0.50 8.16 3.81
36 INT40712 Gene_expression of EPX 4 9 0.78 5.93 3.6
37 INT12923 Negative_regulation of Atp9a 1 17 0.35 7.87 3.52
38 INT203137 Binding of Mif 1 6 0.31 9.46 2.71
39 INT40748 Negative_regulation of Mif 1 6 0.56 8.33 2.46
40 INT63505 Negative_regulation of F2 1 18 0.57 7.4 2.2
41 INT155807 Positive_regulation of Gene_expression of Ccl4 1 8 0.40 5.13 1.9
42 INT253756 Gene_expression of Apex1 9 1 0.14 7.47 1.84
43 INT253755 Regulation of Hmgb1 5 7 0.55 6.23 1.8
44 INT253751 Localization of Lif 1 3 0.73 3.94 1.58
45 INT155992 Gene_expression of THBD 2 16 0.66 17 1.24
46 INT215077 Negative_regulation of Positive_regulation of Hmgb1 5 3 0.42 5.09 1.05
47 INT198669 Binding of THBD 1 5 0.10 4.45 0.75
48 INT77000 Protein_catabolism of Fgg 1 5 0.04 3.57 0.64
49 INT253750 Positive_regulation of Gene_expression of Apex1 2 1 0.10 1.43 0.64
50 INT215070 Regulation of Localization of Hmgb1 1 4 0.26 2.23 0.49
51 INT227426 Positive_regulation of Apex1 3 2 0.08 1.98 0.23
52 INT253754 Negative_regulation of Gpr77 1 1 0.08 1.15 0.22
53 INT253752 Negative_regulation of Localization of Apex1 2 1 0.08 1.26 0.2
54 INT190501 Regulation of Apex1 1 1 0.12 0.32 0.1
55 INT114084 Binding of ATP8A1 1 1 0.01 0.42 0.1
56 INT253749 Negative_regulation of Hspa1a 1 2 0.32 1.25 0.09
57 INT253758 Negative_regulation of TSN 1 1 0.05 0.23 0.07
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