J:F1000 Med Rep

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT335644 CTSB Positive_regulation of F2RL1 1 2 0.02 2.58 0.82
2 INT334901 LDLR Positive_regulation of Crp 1 1 0.00 1.48 0.51
3 INT150393 Binding of CASP1 and MEFV 2 1 0.16 2.48 0.45
4 INT335643 CTSB Positive_regulation of PAR4 1 1 0.01 1.3 0.41
5 INT334879 CASP1 Regulation of IL1B 1 1 0.03 1.63 0.31
6 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 1 0.03 1.41 0.1
7 INT334894 Binding of CALCR and ARMC9 1 1 0.01 0.41 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 4 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 1 924 0.59 772.91 331.98
3 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
4 INT626 Localization of CALCA 1 289 0.81 125.39 221.15
5 INT6481 Binding of TNF 2 624 0.48 510.2 214.82
6 INT15515 Positive_regulation of Crp 1 700 0.70 604.24 150.15
7 INT1273 Gene_expression of Avp 2 356 0.78 90.56 138.7
8 INT5940 Negative_regulation of Avp 1 236 0.59 67.86 101.2
9 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
10 INT1724 Negative_regulation of ACE 5 437 0.59 315.64 74.48
11 INT11380 Negative_regulation of IL1B 6 215 0.59 125.62 72.35
12 INT7344 Gene_expression of TAC1 1 132 0.75 35.48 68.26
13 INT671 Positive_regulation of Cea 7 221 0.69 164.5 47.79
14 INT9383 Localization of TRPV1 1 98 0.81 33.23 46.24
15 INT2774 Binding of Crp 1 241 0.48 195.89 44.39
16 INT60710 Gene_expression of Col7a1 1 217 0.78 113.2 35.2
17 INT6484 Binding of IL1B 4 122 0.47 75.84 35.07
18 INT14497 Gene_expression of GRP 1 82 0.78 17.67 32.27
19 INT3330 Gene_expression of AGT 1 149 0.76 98.65 22.73
20 INT8358 Negative_regulation of Localization of CALCA 1 25 0.59 11.79 21.51
21 INT92354 Localization of ESR1 2 77 0.75 33.04 15.51
22 INT20665 Gene_expression of ACE 1 87 0.78 51.71 14.19
23 INT35467 Gene_expression of DIO2 1 37 0.65 9.56 12.61
24 INT11141 Negative_regulation of Gene_expression of Avp 1 23 0.59 3.85 12.19
25 INT32203 Negative_regulation of Crp 1 48 0.58 32.77 11.89
26 INT14204 Protein_catabolism of KNG1 1 41 0.96 20.94 11.47
27 INT18990 Positive_regulation of GRP 1 32 0.70 5.22 11.23
28 INT61171 Gene_expression of S100A8 1 92 0.76 57.74 9.98
29 INT23676 Gene_expression of Chrna7 3 47 0.75 23.66 9.51
30 INT1118 Gene_expression of C6orf25 1 73 0.77 47.24 9.1
31 INT29121 Positive_regulation of DIO2 1 23 0.67 6.13 8.46
32 INT29794 Regulation of DIO2 1 13 0.44 5.02 6.84
33 INT13406 Negative_regulation of CASP1 2 25 0.57 10.61 6.36
34 INT65265 Positive_regulation of Gene_expression of Col7a1 1 48 0.69 23.81 6.16
35 INT2137 Localization of Cea 2 27 0.70 19.22 6.14
36 INT18677 Gene_expression of F3 1 50 0.65 30.86 5.86
37 INT22839 Gene_expression of F2 1 31 0.74 15.53 5.56
38 INT50105 Localization of CTSB 1 29 0.78 10.98 5.21
39 INT8786 Negative_regulation of ALDH7A1 2 27 0.52 12.81 4.76
40 INT246315 Localization of Ednra 1 22 0.15 2.73 4.64
41 INT36309 Negative_regulation of DIO2 2 18 0.57 6.42 4.51
42 INT30610 Localization of PCa 2 35 0.65 13.91 4.25
43 INT17182 Binding of Cea 1 25 0.48 14.98 4.16
44 INT4649 Positive_regulation of Chrna7 1 17 0.50 5.48 3.92
45 INT15982 Positive_regulation of NLRP3 2 25 0.65 23.19 3.57
46 INT52899 Positive_regulation of TNFRSF1A 1 16 0.46 19.04 3.34
47 INT16976 Negative_regulation of IL36RN 1 6 0.49 5.08 3.31
48 INT57222 Gene_expression of ATF3 1 22 0.78 54.71 3.28
49 INT76430 Gene_expression of SLC1A1 1 2 0.03 0.77 3.15
50 INT64806 Binding of asa 1 10 0.30 4.11 3.14
51 INT110039 Positive_regulation of Nppb 5 38 0.53 34.54 2.88
52 INT116819 Negative_regulation of Localization of TRPV1 1 3 0.43 1.75 2.71
53 INT17857 Negative_regulation of Gene_expression of AGT 1 25 0.46 21.16 2.45
54 INT94042 Positive_regulation of Gene_expression of S100A8 1 15 0.67 13.52 2.44
55 INT345985 Positive_regulation of Gene_expression of SLC1A1 1 1 0.01 0.35 2.2
56 INT149669 Positive_regulation of MEFV 2 12 0.46 14.17 2.07
57 INT92129 Positive_regulation of Gene_expression of F3 2 13 0.08 12.13 2.02
58 INT49377 Negative_regulation of Scd1 1 11 0.49 9.84 1.88
59 INT47425 Localization of Chrna7 1 11 0.81 6.7 1.86
60 INT62349 Negative_regulation of Protein_catabolism of KNG1 1 8 0.42 6.47 1.86
61 INT129534 Gene_expression of Nppb 4 19 0.58 23.68 1.6
62 INT92934 Gene_expression of GRPR 3 2 0.67 5.13 1.57
63 INT118267 Negative_regulation of ARSD 1 14 0.36 8.27 1.44
64 INT108423 Negative_regulation of Pde12 1 3 0.06 1.81 1.26
65 INT162831 Regulation of ARSD 2 13 0.35 6.17 1.19
66 INT99003 Regulation of Vcam1 1 7 0.41 6.91 1.04
67 INT115069 Positive_regulation of Localization of Cea 2 5 0.34 3.31 0.95
68 INT335647 Gene_expression of OSMR 2 1 0.48 2.78 0.72
69 INT222205 Positive_regulation of PSTPIP1 1 8 0.69 4.69 0.62
70 INT92935 Binding of GRPR 1 2 0.32 1.99 0.62
71 INT69098 Positive_regulation of Gene_expression of F2 1 5 0.66 3.79 0.58
72 INT165066 Gene_expression of GAGE4 1 3 0.09 2.82 0.57
73 INT26073 Gene_expression of Scd1 1 17 0.70 9.17 0.47
74 INT212271 Binding of ARMC9 1 14 0.27 3.29 0.43
75 INT335648 Localization of CTSS 1 1 0.08 1.39 0.41
76 INT183075 Binding of Hypt 1 7 0.22 7.47 0.38
77 INT72455 Transcription of S100A8 1 3 0.69 1.66 0.36
78 INT16808 Binding of Scd1 3 5 0.00 7.18 0.33
79 INT192406 Regulation of Ighm 1 16 0.31 5.58 0.29
80 INT274601 Regulation of PSTPIP1 1 3 0.45 3.76 0.28
81 INT334903 Positive_regulation of Localization of Chrna7 1 2 0.04 0.83 0.23
82 INT236278 Negative_regulation of CADPS 1 4 0.36 2.16 0.22
83 INT334907 Protein_catabolism of Nppb 1 2 0.56 8.28 0.22
84 INT168001 Localization of Cms1 1 5 0.59 1.78 0.21
85 INT334889 Positive_regulation of Transcription of MRPL14 1 1 0.07 0.79 0.21
86 INT334883 Positive_regulation of Transcription of CBFA2T2 1 1 0.03 0.79 0.21
87 INT334884 Transcription of CBFA2T2 1 1 0.04 0.78 0.21
88 INT334887 Positive_regulation of Gene_expression of CBFA2T2 1 1 0.03 0.79 0.21
89 INT334888 Gene_expression of CBFA2T2 1 1 0.05 0.78 0.21
90 INT334885 Transcription of MRPL14 1 1 0.10 0.79 0.21
91 INT334886 Gene_expression of MRPL14 1 1 0.11 0.79 0.21
92 INT334890 Positive_regulation of Gene_expression of MRPL14 1 1 0.07 0.79 0.21
93 INT334891 Positive_regulation of Transcription of S100A8 1 1 0.06 0.79 0.21
94 INT211657 Localization of Arg1 1 4 0.53 3.48 0.2
95 INT334908 Localization of Pde12 1 1 0.06 1.25 0.19
96 INT246314 Gene_expression of Dio2 2 2 0.60 0.79 0.14
97 INT170734 Positive_regulation of Gene_expression of Scd1 1 5 0.48 5.87 0.13
98 INT335654 Negative_regulation of Gene_expression of DIO2 1 1 0.17 0.72 0.1
99 INT334904 Localization of ALKBH2 1 1 0.01 0.5 0.07
100 INT335649 Regulation of Tg(EGFR)4Jlj 1 1 0.10 0.36 0
101 INT335650 Gene_expression of Tg(EGFR)4Jlj 4 1 0.09 0.49 0
102 INT335651 Positive_regulation of Gene_expression of Tg(EGFR)4Jlj 8 1 0.07 1.01 0
103 INT335653 Positive_regulation of Tg(EGFR)4Jlj 2 1 0.07 0.24 0
104 INT335652 Regulation of Gene_expression of Dio2 1 1 0.39 0.36 0
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