J:Free Radic. Biol. Med.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT90387	ROS1 Positive_regulation of NFKB1	4	2	0.32	2.35	0.87
2	INT165677	NFE2L2 Negative_regulation of Positive_regulation of HMOX1	1	1	0.40	0.32	0.44
3	INT165678	NFE2L2 Negative_regulation of HMOX1	1	1	0.40	0.31	0.43
4	INT166093	Negative_regulation of ROS1 Negative_regulation of Positive_regulation of EGFR	1	1	0.12	0.33	0.28
5	INT166094	Negative_regulation of CSK Negative_regulation of Positive_regulation of EGFR	1	1	0.02	0.33	0.28

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT68684	Gene_expression of VEGFA	1	2371	0.78	1742.52	259.2
2	INT50674	Gene_expression of PTGS2	1	459	0.78	253.33	118.51
3	INT69440	Gene_expression of ROS1	6	752	0.78	477.64	103.83
4	INT48408	Gene_expression of ICAM1	2	494	0.78	340.08	88.6
5	INT2431	Positive_regulation of Mpo	3	275	0.70	211.99	78.47
6	INT73048	Gene_expression of MMP9	1	268	0.77	159.75	57.81
7	INT18883	Negative_regulation of RYBP	2	53	0.56	21.14	57.52
8	INT26500	Gene_expression of MMP2	2	201	0.78	110.57	46.9
9	INT69437	Positive_regulation of ROS1	2	328	0.58	222.83	40.56
10	INT55135	Positive_regulation of Gene_expression of PTGS2	1	137	0.70	80.32	38.46
11	INT18774	Gene_expression of RYBP	2	67	0.65	47.66	37.59
12	INT63349	Gene_expression of PECAM1	2	199	0.75	166.03	36.76
13	INT84260	Positive_regulation of Mapk8	1	124	0.69	72.84	35.98
14	INT74563	Positive_regulation of Gene_expression of ROS1	4	258	0.61	168.18	34.08
15	INT95734	Phosphorylation of Mapk8	1	108	0.82	49.92	33.52
16	INT62830	Gene_expression of VCAM1	1	149	0.78	125.23	32.4
17	INT5650	Gene_expression of Mpo	6	117	0.77	80.27	26.42
18	INT34487	Localization of MMP2	1	56	0.81	31.41	23.61
19	INT55170	Gene_expression of NFKB1	1	97	0.77	52.75	23.04
20	INT99068	Gene_expression of Mapk8	2	62	0.78	33.57	21.25
21	INT89396	Phosphorylation of AKT1	3	225	0.82	111.66	19.61
22	INT62826	Negative_regulation of Gene_expression of ICAM1	2	75	0.58	46.39	17.72
23	INT104493	Negative_regulation of Mapk8	3	56	0.53	27.76	16.86
24	INT36262	Positive_regulation of Tbce	1	35	0.49	28.79	14.33
25	INT39733	Localization of NFKB1	1	59	0.79	22.76	13.99
26	INT95738	Positive_regulation of Phosphorylation of Mapk8	1	40	0.70	23.46	13.88
27	INT69435	Negative_regulation of ROS1	1	74	0.51	50.38	13.71
28	INT116528	Gene_expression of HMOX1	3	106	0.78	86.13	12.8
29	INT4460	Regulation of Mpo	1	44	0.62	31.16	12.11
30	INT19795	Positive_regulation of EGFR	3	161	0.70	103.69	11.55
31	INT111223	Positive_regulation of HMOX1	9	47	0.70	39.14	10.92
32	INT41627	Gene_expression of Nqo1	1	33	0.65	4.58	10.48
33	INT2792	Gene_expression of Mb	1	91	0.76	41.56	10.25
34	INT76759	Positive_regulation of RFFL	2	31	0.35	29.15	9.9
35	INT126031	Negative_regulation of Gene_expression of MMP9	1	40	0.57	22.71	9.79
36	INT12563	Localization of Mpo	3	33	0.81	20.99	9.58
37	INT91509	Localization of CYC1	3	39	0.78	34.74	7.17
38	INT2442	Localization of Mb	1	38	0.80	24.74	6.33
39	INT111545	Phosphorylation of VEGFA	1	50	0.76	22.19	5.88
40	INT3306	Localization of Tbce	1	16	0.12	8.24	5.71
41	INT82611	Negative_regulation of SRC	1	30	0.57	20.16	5.47
42	INT128922	Negative_regulation of Gene_expression of Mapk8	2	6	0.34	3.93	5.36
43	INT66209	Negative_regulation of Localization of NFKB1	1	23	0.58	8.2	5.31
44	INT34654	Negative_regulation of Gene_expression of RYBP	2	7	0.28	2.89	5.31
45	INT116527	Positive_regulation of Gene_expression of HMOX1	2	29	0.70	25.79	4.87
46	INT28269	Negative_regulation of Adp	1	18	0.36	5.98	4.74
47	INT35599	Negative_regulation of Nqo1	1	25	0.54	4.6	4.42
48	INT62821	Negative_regulation of Gene_expression of VCAM1	1	21	0.54	12.24	4.41
49	INT25634	Binding of Mpo	1	21	0.48	14.78	4.39
50	INT26337	Negative_regulation of Hmmr	1	6	0.30	1.11	4.01
51	INT111514	Positive_regulation of Gene_expression of Mpo	1	20	0.49	15.13	3.88
52	INT105882	Phosphorylation of Bcl2	1	11	0.59	8.15	3.73
53	INT79231	Positive_regulation of Gene_expression of NFKB1	1	18	0.67	9.16	3.66
54	INT134149	Negative_regulation of Gene_expression of NFKB1	1	7	0.55	4.25	3.63
55	INT91511	Positive_regulation of Localization of CYC1	2	15	0.67	14.68	3.57
56	INT95119	Localization of CYCS	3	23	0.78	14.86	3.49
57	INT69438	Negative_regulation of Positive_regulation of ROS1	2	20	0.48	10.6	3.33
58	INT163529	Negative_regulation of Positive_regulation of Mapk8	1	14	0.43	8.37	3.2
59	INT139801	Phosphorylation of NFKB1	1	9	0.66	5.2	3.13
60	INT105883	Positive_regulation of Phosphorylation of Bcl2	1	8	0.32	5.67	1.86
61	INT164864	Positive_regulation of Negative_regulation of Mapk8	2	1	0.31	1.33	1.82
62	INT122468	Negative_regulation of Localization of CYC1	1	8	0.57	7.75	1.74
63	INT101816	Localization of NFE2L2	7	17	0.77	6.91	1.69
64	INT113785	Negative_regulation of Eef1a2	3	15	0.31	1.33	1.48
65	INT91508	Positive_regulation of Gene_expression of CYC1	1	5	0.49	3.76	1.46
66	INT105086	Positive_regulation of CYCS	1	9	0.49	5.82	1.45
67	INT165680	Transcription of HMOX1	1	7	0.71	11.2	1.41
68	INT91506	Gene_expression of CYC1	1	6	0.65	2.7	1.37
69	INT105881	Phosphorylation of Bcl2l1	1	3	0.51	1.99	1.31
70	INT127725	Negative_regulation of Positive_regulation of EGFR	2	6	0.57	2.69	1.3
71	INT111340	Positive_regulation of Localization of CYCS	1	7	0.67	4.83	1.19
72	INT135556	Localization of AKT1	1	38	0.69	12.78	1.17
73	INT164863	Positive_regulation of Phosphorylation of Bcl2l1	1	1	0.31	0.57	1.01
74	INT56214	Localization of Tnnt3	1	4	0.77	4.54	0.75
75	INT165681	Positive_regulation of Transcription of HMOX1	1	2	0.69	4.29	0.53
76	INT165682	Phosphorylation of NFE2L2	1	4	0.78	1.53	0.51
77	INT166100	Phosphorylation of MMP2	2	1	0.32	0.56	0.51
78	INT129857	Regulation of Gene_expression of Mpo	1	4	0.42	4.36	0.47
79	INT87460	Gene_expression of Tnnt3	1	4	0.60	2.71	0.46
80	INT158592	Negative_regulation of CSK	1	2	0.19	0.43	0.36
81	INT166099	Phosphorylation of MMP9	1	2	0.41	0.52	0.29
82	INT160766	Localization of HSPA9	1	2	0.78	1.84	0.26
83	INT156337	Positive_regulation of HSPA9	1	2	0.49	0.32	0.23
84	INT160765	Positive_regulation of Localization of HSPA9	1	1	0.49	0.25	0.23
85	INT164561	Negative_regulation of Negative_regulation of Eef1a2	1	1	0.01	0.06	0.1