J:Frontiers in Behavioral Neuroscience

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT328625 NPL Regulation of Phosphorylation of Ephb1 1 3 0.04 0.42 0.7
2 INT328621 Gene_expression of Il1rl1 Positive_regulation of Cfp 1 1 0.00 0.06 0.23
3 INT328923 Car2 Positive_regulation of Prkca 1 1 0.00 0 0.18
4 INT243772 Safb Negative_regulation of Gria1 1 1 0.23 0.84 0.17
5 INT302529 Hal Regulation of Cpz 1 1 0.26 0.43 0.08
6 INT302530 Cpz Regulation of Negative_regulation of Mbp 1 2 0.22 0.1 0.07
7 INT302528 Hal Regulation of Negative_regulation of Mbp 1 2 0.16 0.1 0.07
8 INT243766 Binding of Egr1 and Proc 1 1 0.01 0.2 0.03
9 INT243768 Egr2 Regulation of Gene_expression of Nab2 1 1 0.47 0.14 0
10 INT243767 Egr2 Regulation of Gene_expression of Nab1 1 1 0.63 0.14 0
11 INT243770 Egr1 Regulation of Nab2 1 1 0.28 0.09 0
12 INT243769 Binding of Egr2 and Nab2 1 1 0.39 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 9 3083 0.78 894.43 1639.02
2 INT796 Gene_expression of Penk 1 1902 0.78 275.47 1057.59
3 INT7114 Positive_regulation of Ltp 7 1192 0.62 290.76 755.77
4 INT5202 Positive_regulation of Gene_expression of Fos 1 1163 0.70 319.28 684
5 INT5228 Positive_regulation of Fos 1 934 0.70 209.8 503.87
6 INT76660 Gene_expression of Trpv1 1 691 0.78 329.46 386.42
7 INT439 Localization of Gnrh1 2 976 0.81 100.96 363.25
8 INT16260 Gene_expression of Bdnf 3 671 0.78 283.44 339.1
9 INT63932 Positive_regulation of Ephb1 9 537 0.70 259.67 296.14
10 INT5379 Gene_expression of Fos 2 656 0.78 255.5 292.54
11 INT5591 Regulation of Gene_expression of Fos 1 425 0.62 129.06 265.78
12 INT5501 Regulation of Oprd1 4 283 0.62 55.1 249.9
13 INT6665 Gene_expression of FOS 13 520 0.77 165.31 217.66
14 INT22548 Positive_regulation of Casp3 1 483 0.70 258.78 213.07
15 INT16259 Positive_regulation of Bdnf 2 336 0.70 183.48 209.82
16 INT63934 Phosphorylation of Ephb1 23 377 0.82 150.52 188.66
17 INT6354 Localization of Gabrg1 4 321 0.74 41.41 186.74
18 INT49441 Negative_regulation of Cpox 1 494 0.59 303.22 177.46
19 INT7506 Negative_regulation of Ltp 3 267 0.46 91.01 176.8
20 INT4937 Negative_regulation of Oprd1 4 224 0.59 44.51 171.11
21 INT7628 Gene_expression of Ltp 7 273 0.77 70.21 147.87
22 INT14843 Gene_expression of Gabrg1 5 301 0.77 62.63 139.16
23 INT64161 Positive_regulation of Prkca 4 213 0.70 85.06 129.91
24 INT6323 Positive_regulation of Gabrg1 1 213 0.70 45.08 124.34
25 INT14151 Gene_expression of Casp3 1 311 0.78 140.26 120.68
26 INT92669 Gene_expression of Bdnf 1 309 0.78 178.26 116.68
27 INT16253 Positive_regulation of Gene_expression of Bdnf 2 196 0.70 92.67 113.01
28 INT48923 Gene_expression of Ephb1 4 211 0.77 106.23 109.9
29 INT17459 Positive_regulation of Gene_expression of FOS 5 182 0.67 53.45 96.38
30 INT940 Negative_regulation of Ptgs1 1 219 0.59 104.34 95.97
31 INT4289 Positive_regulation of Localization of Gnrh1 1 202 0.70 12.3 84.01
32 INT10534 Positive_regulation of Trib3 2 209 0.60 78.75 81.48
33 INT63936 Positive_regulation of Phosphorylation of Ephb1 5 131 0.70 49.38 73.16
34 INT13276 Regulation of Ltp 2 107 0.53 30.78 69.13
35 INT5861 Gene_expression of Egr1 8 203 0.78 49.35 68.13
36 INT24989 Positive_regulation of Cfp 5 125 0.61 29.55 64.9
37 INT2761 Regulation of Gabrg1 2 119 0.61 18.8 60.52
38 INT102020 Gene_expression of Creb1 1 190 0.78 57.31 59.77
39 INT5356 Positive_regulation of FOS 3 153 0.69 54.21 56.74
40 INT8528 Negative_regulation of Gene_expression of Fos 1 100 0.59 41.15 55.6
41 INT77855 Gene_expression of Pain1 2 55 0.75 67.42 54.1
42 INT61873 Gene_expression of Arc 1 128 0.78 128.25 52.24
43 INT48920 Negative_regulation of Ephb1 2 107 0.57 43.6 51.02
44 INT55671 Gene_expression of Ik 1 151 0.27 80.1 48.49
45 INT47683 Negative_regulation of Bdnf 1 92 0.59 47.53 43.55
46 INT48929 Regulation of Ephb1 1 71 0.62 24.42 42.11
47 INT60388 Gene_expression of Helt 5 90 0.07 19.18 41.72
48 INT57442 Phosphorylation of Prkca 1 98 0.70 31.58 41.04
49 INT11854 Gene_expression of Il1rl1 1 57 0.77 30.19 38.25
50 INT115649 Gene_expression of Camk2a 2 95 0.78 33.22 38
51 INT17736 Gene_expression of Cfp 8 111 0.65 40.68 36.61
52 INT70437 Negative_regulation of Mdk 1 115 0.57 41.03 35.72
53 INT5862 Positive_regulation of Egr1 1 82 0.70 30.4 33.96
54 INT50308 Binding of Cnr1 2 61 0.48 14.41 33.52
55 INT63935 Positive_regulation of Gene_expression of Ephb1 2 52 0.61 24.3 33.05
56 INT45365 Negative_regulation of Cfp 3 68 0.57 25.44 32.11
57 INT11087 Positive_regulation of Drd2 1 54 0.69 12.4 31.43
58 INT106554 Positive_regulation of Gene_expression of Bdnf 1 73 0.70 42.58 30.77
59 INT64918 Gene_expression of Gria2 2 108 0.74 29.95 29.67
60 INT11796 Positive_regulation of Helt 1 52 0.31 11.7 29.22
61 INT84494 Negative_regulation of Phosphorylation of Ephb1 5 44 0.59 22.34 28.68
62 INT91775 Gene_expression of Slc6a4 1 102 0.78 26.45 28.23
63 INT90313 Negative_regulation of Gene_expression of Casp3 1 57 0.57 22.23 26.77
64 INT16428 Positive_regulation of Gtf3a 1 135 0.20 106.44 26.67
65 INT48979 Regulation of Gene_expression of FOS 1 52 0.61 14.4 25.95
66 INT6054 Positive_regulation of Gene_expression of Egr1 3 67 0.70 18.45 25.93
67 INT57874 Gene_expression of Egr1 20 113 0.78 68.46 24.95
68 INT123386 Negative_regulation of Camk2a 1 48 0.58 12.57 23.78
69 INT76249 Gene_expression of Gria1 3 67 0.75 15.07 22.78
70 INT15326 Phosphorylation of Trib3 2 83 0.55 30.96 22.27
71 INT2386 Gene_expression of Pgr 1 112 0.78 45.46 22.19
72 INT28728 Regulation of Cfp 5 49 0.46 13.15 21.43
73 INT24569 Negative_regulation of Pain1 1 26 0.41 21.82 21.08
74 INT117527 Binding of Prkca 2 25 0.48 6.43 21.05
75 INT129987 Phosphorylation of Gria1 1 63 0.80 20.65 21.02
76 INT102203 Transcription of Bdnf 1 35 0.71 18.26 20.59
77 INT109379 Regulation of Phosphorylation of Ephb1 3 22 0.59 12.58 18.84
78 INT62577 Negative_regulation of Creb1 1 55 0.59 19.68 18.1
79 INT95930 Negative_regulation of Gria2 1 63 0.56 18.37 17.04
80 INT102023 Regulation of Creb1 1 51 0.62 16.29 16.71
81 INT197375 Gene_expression of Car1 1 84 0.65 16.46 16.45
82 INT209 Positive_regulation of Pde5a 1 30 0.21 2.54 16.31
83 INT62861 Regulation of Gria2 1 45 0.60 13.35 16.07
84 INT79458 Localization of Prkca 1 30 0.81 11.13 15.78
85 INT115650 Positive_regulation of Gene_expression of Camk2a 1 37 0.70 17.68 15.73
86 INT125384 Positive_regulation of Pain1 2 23 0.49 17.1 14.83
87 INT11795 Negative_regulation of Helt 1 33 0.28 6.51 14.76
88 INT11855 Positive_regulation of Gene_expression of Il1rl1 1 19 0.69 12.22 14.57
89 INT57878 Positive_regulation of Gene_expression of Egr1 5 36 0.70 20.42 14.45
90 INT84496 Regulation of Positive_regulation of Ephb1 1 18 0.61 10.16 13.92
91 INT13572 Localization of Helt 1 31 0.36 5.85 13.41
92 INT121783 Positive_regulation of Gene_expression of Arc 1 30 0.70 29.22 13.02
93 INT9483 Gene_expression of Junb 1 34 0.78 3.24 12.08
94 INT21850 Gene_expression of Spna1 15 107 0.50 51.4 11.81
95 INT148639 Gene_expression of Uchl1 2 30 0.59 16.76 11.54
96 INT54466 Negative_regulation of Gene_expression of Ltp 1 19 0.38 5.44 10.91
97 INT3301 Positive_regulation of Slc43a3 4 26 0.55 5.48 10.81
98 INT62576 Transcription of Creb1 1 34 0.69 16.97 10.6
99 INT151168 Gene_expression of Pten 1 60 0.78 35.63 10.54
100 INT104441 Binding of NOVA2 2 72 0.42 16.41 10.51
101 INT96298 Negative_regulation of Gria1 10 25 0.57 10.61 9.7
102 INT57876 Positive_regulation of Egr1 14 46 0.70 25.6 9.41
103 INT21846 Localization of Spna1 3 27 0.78 5.14 9.22
104 INT10597 Gene_expression of Cyp19a1 2 27 0.78 7.48 9.11
105 INT119527 Regulation of Camk2a 1 26 0.60 5.55 9.01
106 INT61399 Positive_regulation of Ik 3 21 0.22 10.17 8.75
107 INT34372 Gene_expression of Cfp 3 102 0.67 37.66 8.72
108 INT108643 Gene_expression of Dlg4 1 61 0.76 8.63 8.58
109 INT33944 Regulation of Helt 2 13 0.24 2.86 8.49
110 INT70572 Gene_expression of Fst 1 33 0.78 5.22 8.24
111 INT193663 Binding of Pain1 2 9 0.36 8.84 8.04
112 INT67037 Gene_expression of Sod1 1 121 0.78 59.32 7.99
113 INT101189 Transcription of Gtf3a 3 49 0.17 24.39 7.93
114 INT78226 Gene_expression of Mbp 2 43 0.75 22.14 7.79
115 INT153371 Binding of Cfp 1 27 0.47 7.33 7.48
116 INT202868 Positive_regulation of Car1 1 30 0.44 15.48 7.42
117 INT73760 Transcription of Drd2 1 14 0.72 2.11 7.19
118 INT6057 Negative_regulation of Gene_expression of Egr1 2 17 0.57 4.17 7.17
119 INT23782 Positive_regulation of Spna1 1 58 0.50 35.41 6.94
120 INT9289 Gene_expression of Htr3a 4 15 0.75 4.43 6.69
121 INT53311 Positive_regulation of Gene_expression of Cfp 4 20 0.42 4.39 6.62
122 INT48922 Regulation of Gene_expression of Ephb1 1 14 0.50 5.73 6.47
123 INT66925 Positive_regulation of Gene_expression of Ik 1 22 0.15 10.47 6.4
124 INT92971 Binding of Creb1 1 31 0.47 11.3 6.22
125 INT34370 Positive_regulation of Cfp 3 26 0.46 15.21 6.12
126 INT245587 Regulation of Car1 1 13 0.27 4.68 5.72
127 INT91754 Gene_expression of Cp 4 42 0.77 21.97 5.38
128 INT125996 Gene_expression of Nsf 1 7 0.75 1.73 5.3
129 INT119711 Positive_regulation of Slc6a4 1 16 0.69 4.44 5.21
130 INT22825 Regulation of Gtf3a 1 36 0.25 19.93 5.03
131 INT328620 Phosphorylation of Cfp 7 8 0.39 5.05 4.87
132 INT79460 Positive_regulation of Localization of Prkca 1 11 0.70 2.72 4.71
133 INT54911 Localization of FOS 1 20 0.78 3.27 4.56
134 INT113107 Phosphorylation of Hist1h3f 1 21 0.51 8.01 4.45
135 INT117936 Regulation of Gene_expression of Egr1 2 18 0.60 9.37 4.45
136 INT65056 Binding of Ntrk2 1 20 0.36 3.72 4.42
137 INT192680 Localization of Pain1 1 6 0.73 5.01 4.42
138 INT88156 Regulation of Gria1 1 12 0.54 2.5 4.06
139 INT159119 Negative_regulation of Car1 1 17 0.37 6.6 4.01
140 INT210975 Regulation of Cfp 1 10 0.24 5.3 3.93
141 INT217102 Gene_expression of Egr2 24 50 0.78 10.91 3.89
142 INT129990 Positive_regulation of Phosphorylation of Gria1 1 11 0.61 3.44 3.87
143 INT100161 Positive_regulation of Phgdh 1 6 0.49 0.77 3.81
144 INT58602 Gene_expression of HMI 9 34 0.65 25.26 3.74
145 INT24711 Negative_regulation of Spna1 1 22 0.35 14.75 3.59
146 INT212563 Gene_expression of Adrm1 2 26 0.13 11.46 3.58
147 INT151171 Positive_regulation of Pten 1 20 0.55 13.3 3.54
148 INT61875 Negative_regulation of Arc 1 4 0.34 5.61 3.49
149 INT22502 Gene_expression of Hal 3 21 0.53 9.8 3.32
150 INT206194 Transcription of Ltp 1 6 0.58 3.28 3.32
151 INT39884 Negative_regulation of Mbp 6 23 0.56 11.93 3.21
152 INT126575 Negative_regulation of Ppi-rs 3 21 0.14 12.94 3.2
153 INT39249 Positive_regulation of NPL 1 5 0.41 2.72 3.18
154 INT113996 Gene_expression of RS1 1 23 0.72 7.7 3.16
155 INT67770 Regulation of NPL 2 4 0.18 0.85 3.13
156 INT146300 Binding of RS1 1 31 0.22 29.55 3.04
157 INT126577 Gene_expression of Ppi-rs 3 25 0.14 19.1 2.74
158 INT143189 Positive_regulation of Binding of Cnr1 1 3 0.35 0.37 2.74
159 INT52655 Regulation of Ik 1 6 0.23 2.09 2.68
160 INT91899 Binding of Sod1 1 17 0.47 11.56 2.63
161 INT201646 Negative_regulation of Transcription of Bdnf 1 8 0.58 7.14 2.59
162 INT139148 Negative_regulation of Gene_expression of Gria1 1 6 0.51 0.89 2.56
163 INT39180 Gene_expression of NPL 3 7 0.38 3.61 2.48
164 INT249036 Gene_expression of Rnf103 13 1 0.78 7.53 2.42
165 INT74262 Negative_regulation of Egr1 3 15 0.57 7.51 2.41
166 INT139556 Positive_regulation of Chrna4 1 10 0.25 4.52 2.36
167 INT110184 Binding of HMI 1 9 0.28 5.52 2.24
168 INT52601 Positive_regulation of Il1rl1 1 12 0.66 1.34 2.22
169 INT81154 Gene_expression of HCRT 1 10 0.75 5.32 2.22
170 INT49631 Gene_expression of Slc43a3 2 14 0.59 4.15 2.15
171 INT15243 Regulation of Egr1 7 19 0.61 7.6 2.13
172 INT113999 Positive_regulation of RS1 1 12 0.64 2.41 2.04
173 INT163980 Gene_expression of Hdc 6 12 0.65 4.47 1.96
174 INT81347 Regulation of Cyp19a1 1 7 0.40 2.1 1.94
175 INT71807 Negative_regulation of Cp 3 18 0.58 8.9 1.88
176 INT217094 Positive_regulation of Egr2 10 17 0.69 5.31 1.87
177 INT14257 Localization of TSPO 1 9 0.73 1.48 1.87
178 INT328618 Negative_regulation of Phosphorylation of Cfp 2 3 0.28 2.51 1.81
179 INT158374 Negative_regulation of Aadac 1 13 0.07 7.19 1.76
180 INT99444 Positive_regulation of Proc 1 15 0.45 9.18 1.75
181 INT57875 Positive_regulation of Positive_regulation of Egr1 1 6 0.49 2.74 1.75
182 INT29833 Binding of Spna1 2 39 0.27 19.4 1.74
183 INT137689 Regulation of Gene_expression of Cfp 1 4 0.23 0.91 1.7
184 INT42311 Regulation of HMI 1 9 0.43 0 1.64
185 INT168558 Positive_regulation of Gene_expression of Cfp 1 10 0.43 4.54 1.59
186 INT57877 Negative_regulation of Positive_regulation of Egr1 1 4 0.42 1.63 1.57
187 INT163535 Negative_regulation of Sgpp1 2 6 0.13 3.35 1.52
188 INT91900 Localization of Sod1 1 12 0.77 6.62 1.51
189 INT192679 Positive_regulation of Localization of Pain1 1 3 0.49 1.94 1.41
190 INT99639 Regulation of Phosphorylation of Trib3 1 6 0.14 0.44 1.36
191 INT141344 Transcription of Egr1 3 11 0.70 5.59 1.34
192 INT261406 Positive_regulation of Positive_regulation of Car1 1 1 0.27 1.09 1.34
193 INT26786 Positive_regulation of Uchl1 1 7 0.34 1.37 1.32
194 INT328619 Positive_regulation of Phosphorylation of Cfp 1 2 0.33 1.4 1.31
195 INT249038 Positive_regulation of Gene_expression of Rnf103 6 1 0.70 3.66 1.29
196 INT243771 Negative_regulation of Safb 1 7 0.26 0.77 1.23
197 INT218779 Negative_regulation of Cfp 4 7 0.14 2.89 1.2
198 INT328623 Phosphorylation of NPL 4 1 0.05 0.5 1.17
199 INT111588 Gene_expression of Alox12 1 3 0.59 0.4 1.16
200 INT84855 Negative_regulation of Rps6ka3 1 3 0.37 0.38 1.13
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