J:Frontiers in Cellular Neuroscience

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT302369 Binding of Arx and Dlx1 1 1 0.34 0 0.43
2 INT302371 Dlx1 Regulation of Gene_expression of Arx 1 1 0.28 0 0.35
3 INT302367 Dlx2 Regulation of Gene_expression of Arx 1 1 0.59 0.23 0.22
4 INT302372 Arx Negative_regulation of Gene_expression of Calb2 1 1 0.13 0.05 0.18
5 INT307651 Gabbr1 Regulation of Gene_expression of Bdnf 1 1 0.00 0 0.16
6 INT307652 Gabbr1 Regulation of Localization of Bdnf 1 1 0.00 0 0.16
7 INT345999 Binding of Fgf2 and Gfap 1 2 0.37 0.09 0.16
8 INT345996 Fgf2 Positive_regulation of Gene_expression of Gfap 1 1 0.71 0.13 0.15
9 INT307650 Gabrg1 Regulation of Bdnf 1 1 0.06 0 0.15
10 INT345998 Fgf2 Positive_regulation of Gfap 1 1 0.48 0.09 0.13
11 INT345997 Binding of Gfap and Scq1 1 1 0.15 0.09 0.12
12 INT302364 Binding of Arx and Reln 1 1 0.32 1.25 0
13 INT302370 Binding of Arx and Dcx 1 1 0.35 1.25 0
14 INT302373 Binding of Arx and Tuba1a 1 1 0.30 1.26 0
15 INT302368 Binding of Arx and Pafah1b1 1 1 0.27 1.25 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT7114 Positive_regulation of Ltp 3 1192 0.62 290.76 755.77
2 INT3439 Localization of Abat 4 1017 0.78 112.39 727.06
3 INT76660 Gene_expression of Trpv1 1 691 0.78 329.46 386.42
4 INT16260 Gene_expression of Bdnf 2 671 0.78 283.44 339.1
5 INT2909 Positive_regulation of Abat 2 334 0.70 62.1 256.43
6 INT11009 Phosphorylation of Creb1 4 458 0.82 111.34 221.97
7 INT2211 Negative_regulation of Abat 1 267 0.59 66.51 200.98
8 INT6354 Localization of Gabrg1 5 321 0.74 41.41 186.74
9 INT4829 Positive_regulation of Localization of Abat 2 199 0.55 20.91 150.48
10 INT7628 Gene_expression of Ltp 1 273 0.77 70.21 147.87
11 INT14843 Gene_expression of Gabrg1 31 301 0.77 62.63 139.16
12 INT64161 Positive_regulation of Prkca 1 213 0.70 85.06 129.91
13 INT6323 Positive_regulation of Gabrg1 11 213 0.70 45.08 124.34
14 INT92669 Gene_expression of Bdnf 6 309 0.78 178.26 116.68
15 INT11011 Positive_regulation of Phosphorylation of Creb1 1 190 0.70 49.25 112.01
16 INT49651 Gene_expression of Creb1 1 276 0.78 114.77 111.96
17 INT3537 Positive_regulation of Car2 3 413 0.56 103.51 94.35
18 INT9516 Negative_regulation of Gabrg1 12 149 0.53 27.83 91.02
19 INT67682 Localization of Bdnf 1 204 0.81 72.36 88.92
20 INT8962 Gene_expression of Cpe 1 110 0.71 39.67 71.67
21 INT6894 Gene_expression of CNR1 3 168 0.78 74.07 62.84
22 INT18981 Gene_expression of ABAT 9 78 0.68 38.35 61.36
23 INT2761 Regulation of Gabrg1 4 119 0.61 18.8 60.52
24 INT6034 Binding of Gabrg1 4 115 0.47 17.48 51.92
25 INT62630 Positive_regulation of CNR1 1 86 0.70 40.34 51.51
26 INT19488 Localization of ABAT 4 56 0.69 21.51 50.56
27 INT30170 Gene_expression of Car2 2 330 0.66 77.26 46.76
28 INT42980 Gene_expression of GAD1 4 139 0.69 94.77 45.11
29 INT47683 Negative_regulation of Bdnf 2 92 0.59 47.53 43.55
30 INT60388 Gene_expression of Helt 5 90 0.07 19.18 41.72
31 INT16261 Transcription of Bdnf 1 101 0.72 49.41 40.64
32 INT16455 Gene_expression of Drd2 1 116 0.78 22.71 38.47
33 INT43507 Gene_expression of Gabbr1 1 79 0.78 28.53 38.22
34 INT6417 Negative_regulation of ABAT 2 49 0.51 19.6 36.81
35 INT12029 Gene_expression of Car1 3 143 0.67 29.69 36.39
36 INT103172 Gene_expression of Slc12a5 12 81 0.77 39.45 36.22
37 INT14031 Gene_expression of Npy 1 107 0.78 36.48 35.4
38 INT11087 Positive_regulation of Drd2 1 54 0.69 12.4 31.43
39 INT64164 Regulation of Prkca 1 34 0.62 10.44 30.99
40 INT106554 Positive_regulation of Gene_expression of Bdnf 1 73 0.70 42.58 30.77
41 INT66200 Gene_expression of Gfap 7 215 0.78 88.04 28.25
42 INT13145 Positive_regulation of Car1 1 60 0.70 16.32 23.23
43 INT17962 Regulation of Car2 5 124 0.41 33.98 22.71
44 INT23564 Negative_regulation of Car2 3 103 0.50 27.28 21.86
45 INT103169 Negative_regulation of Slc12a5 1 38 0.58 27.75 20.81
46 INT10442 Negative_regulation of CNR1 1 47 0.59 20.88 20.2
47 INT33327 Positive_regulation of Gene_expression of Gabrg1 7 39 0.69 9.68 18.82
48 INT18621 Binding of ABAT 4 28 0.36 9.88 18.04
49 INT13244 Binding of Helt 1 30 0.31 4.56 18.01
50 INT21132 Gene_expression of GABRB3 19 36 0.33 11.32 17.61
51 INT102903 Regulation of Gene_expression of Bdnf 1 35 0.62 20.1 17.42
52 INT170335 Gene_expression of INCENP 1 176 0.54 91.62 15.31
53 INT11795 Negative_regulation of Helt 4 33 0.28 6.51 14.76
54 INT103170 Negative_regulation of Gene_expression of Slc12a5 1 26 0.58 17.25 14.4
55 INT28314 Negative_regulation of Gene_expression of Gabrg1 6 29 0.44 12.56 13.8
56 INT21646 Positive_regulation of Npy 1 40 0.70 31.31 13.57
57 INT57187 Positive_regulation of Gfap 3 49 0.69 27.59 11.46
58 INT101474 Positive_regulation of Gene_expression of Gfap 1 61 0.70 38.3 10.35
59 INT5476 Regulation of Gabbr1 1 21 0.45 4.01 10.26
60 INT35284 Positive_regulation of Chrm1 1 14 0.67 5.64 10.11
61 INT14881 Gene_expression of Car3 3 49 0.73 14.89 9.94
62 INT32239 Gene_expression of Car3 2 38 0.67 6.86 9.76
63 INT96637 Gene_expression of Gad2 3 21 0.76 8.15 9.53
64 INT57039 Positive_regulation of Gene_expression of Drd2 1 16 0.50 1.98 9.48
65 INT21794 Positive_regulation of Gene_expression of Npy 1 20 0.70 8.44 9.3
66 INT46112 Regulation of GAD1 1 15 0.52 11.09 8.37
67 INT92680 Gene_expression of Fgf2 20 59 0.77 28.11 8.12
68 INT10444 Positive_regulation of Gene_expression of CNR1 1 18 0.69 8.69 7.84
69 INT202868 Positive_regulation of Car1 3 30 0.44 15.48 7.42
70 INT12032 Negative_regulation of Gene_expression of Car1 1 16 0.34 7.23 7.03
71 INT155988 Regulation of Localization of ABAT 3 5 0.24 2.19 6.59
72 INT48239 Binding of Gtf3a 1 52 0.33 23.14 6.45
73 INT103171 Positive_regulation of Slc12a5 1 15 0.51 3.6 6.25
74 INT185252 Gene_expression of Dlx2 2 7 0.71 8.8 6.24
75 INT157121 Gene_expression of GAD2 9 15 0.67 7.21 5.91
76 INT56047 Negative_regulation of Transcription of Bdnf 1 16 0.59 8.02 5.67
77 INT170516 Negative_regulation of Gene_expression of Car2 1 35 0.35 9.4 5.48
78 INT91754 Gene_expression of Cp 3 42 0.77 21.97 5.38
79 INT30800 Localization of Car3 1 11 0.80 0.5 5.21
80 INT92679 Positive_regulation of Fgf2 11 13 0.69 11.43 5.18
81 INT45824 Regulation of Positive_regulation of Abat 1 6 0.24 1.2 5.16
82 INT146488 Gene_expression of Slc12a2 1 16 0.73 4.63 5.11
83 INT302338 Gene_expression of Arx 23 1 0.77 2.8 4.93
84 INT49060 Negative_regulation of Camk2a 1 10 0.45 2.59 4.67
85 INT128353 Negative_regulation of Car3 1 16 0.37 4.93 4.61
86 INT76884 Positive_regulation of Cp 2 22 0.69 12.84 4.6
87 INT75629 Gene_expression of Mtap2 2 41 0.66 8.19 4.51
88 INT15450 Positive_regulation of Gene_expression of Cpe 1 11 0.34 4.53 4.34
89 INT139130 Positive_regulation of Gene_expression of Slc12a5 7 8 0.51 4.43 4.33
90 INT76467 Regulation of Gene_expression of Car2 1 41 0.37 12.88 4.21
91 INT113137 Positive_regulation of Ppp1r1b 1 14 0.65 0.89 4.21
92 INT15001 Localization of Gfap 5 29 0.75 6.71 4.1
93 INT80405 Gene_expression of Gnptab 1 7 0.06 0.52 4.03
94 INT196736 Gene_expression of Ppp1r1b 2 24 0.55 2.01 3.99
95 INT183560 Binding of GABRB3 5 12 0.23 2.59 3.77
96 INT14880 Positive_regulation of Car3 1 14 0.65 9.19 3.73
97 INT15002 Regulation of Gfap 2 17 0.37 5.34 3.61
98 INT118644 Regulation of Slc12a2 1 5 0.45 2.43 3.6
99 INT127980 Gene_expression of Trpc3 1 13 0.75 2.53 3.52
100 INT168003 Localization of Fgf2 9 24 0.80 12.52 3.31
101 INT318271 Gene_expression of SLC32A1 6 7 0.44 2.74 3.28
102 INT163066 Transcription of Gfap 1 12 0.69 4.47 3.21
103 INT91418 Transcription of Gabrg1 2 11 0.62 1.12 3.16
104 INT261712 Regulation of GABRB3 1 6 0.09 3.03 3.14
105 INT10443 Regulation of Gene_expression of CNR1 1 10 0.50 3.96 3.06
106 INT98686 Gene_expression of Calb2 3 28 0.51 12.07 2.84
107 INT54495 Binding of GABBR1 1 9 0.35 1.82 2.76
108 INT14883 Regulation of Car3 1 8 0.58 5.57 2.75
109 INT152927 Negative_regulation of Mapk1 1 16 0.41 5.85 2.73
110 INT292993 Positive_regulation of Gene_expression of GABRB3 2 4 0.17 0.9 2.63
111 INT66199 Negative_regulation of Gfap 1 14 0.46 6.88 2.57
112 INT292992 Negative_regulation of Gene_expression of GABRB3 3 3 0.15 0.78 2.41
113 INT21130 Positive_regulation of GABRB3 2 4 0.27 1.88 2.21
114 INT24265 Negative_regulation of Ik 1 11 0.51 0 2.17
115 INT302340 Positive_regulation of Gene_expression of Dlx2 1 2 0.64 3.43 2.15
116 INT87436 Regulation of Fgf2 4 6 0.45 3.95 2.03
117 INT207830 Localization of GAD2 1 10 0.65 0.49 1.97
118 INT101475 Regulation of Gene_expression of Gfap 1 8 0.62 4.77 1.96
119 INT112980 Regulation of Positive_regulation of Gabrg1 1 5 0.26 0.62 1.94
120 INT15506 Localization of Cp 1 11 0.80 4.26 1.9
121 INT245669 Negative_regulation of Gene_expression of Car3 1 7 0.37 1.87 1.9
122 INT71807 Negative_regulation of Cp 3 18 0.58 8.9 1.88
123 INT210693 Positive_regulation of Gene_expression of Slc12a2 1 5 0.46 1.3 1.77
124 INT130264 Negative_regulation of Gene_expression of Car3 1 3 0.32 0.94 1.74
125 INT92677 Positive_regulation of Gene_expression of Fgf2 4 11 0.69 4.25 1.68
126 INT88726 Gene_expression of HPRT1 1 36 0.78 10.12 1.58
127 INT305756 Gene_expression of Isg15 2 4 0.59 0.46 1.52
128 INT243876 Gene_expression of GPHN 5 8 0.75 2.63 1.49
129 INT36148 Binding of GAD1 1 10 0.41 7.91 1.47
130 INT114080 Negative_regulation of Negative_regulation of ABAT 1 3 0.38 1.53 1.47
131 INT302345 Positive_regulation of Gene_expression of Arx 8 1 0.69 1.06 1.4
132 INT183557 Localization of GABRB3 4 3 0.46 1.01 1.34
133 INT13530 Negative_regulation of GABRB3 1 4 0.17 1.48 1.31
134 INT318286 Gene_expression of Od 11 1 0.45 0.5 1.31
135 INT134913 Positive_regulation of Localization of Gfap 1 3 0.50 1.02 1.29
136 INT1867 Positive_regulation of GABBR1 2 6 0.69 0.55 1.18
137 INT96643 Positive_regulation of Gene_expression of Gad2 2 3 0.49 0.15 1.18
138 INT292991 Negative_regulation of Localization of GABRB3 1 2 0.13 0.44 1.18
139 INT144509 Gene_expression of Scq1 1 2 0.28 0.91 1.16
140 INT89105 Gene_expression of Gapdh 1 27 0.75 4.32 1.15
141 INT161968 Positive_regulation of Gene_expression of GAD2 1 2 0.40 0.91 1.04
142 INT77856 Binding of Cps1 1 6 0.30 2.32 0.95
143 INT32693 Positive_regulation of Gene_expression of Car3 1 6 0.42 2.7 0.89
144 INT322477 Negative_regulation of Binding of Gabrg1 1 2 0.41 0.47 0.87
145 INT178498 Negative_regulation of Fgf2 2 11 0.42 4.21 0.84
146 INT122472 Positive_regulation of Positive_regulation of Npy 1 6 0.51 2.66 0.83
147 INT302342 Localization of Arx 6 1 0.80 0.94 0.83
148 INT294805 Gene_expression of Dlx1 2 4 0.70 0.45 0.81
149 INT92188 Positive_regulation of Isg15 2 4 0.19 2.21 0.8
150 INT318278 Regulation of Gene_expression of GABRB3 3 1 0.14 0.47 0.77
151 INT247935 Transcription of Car1 1 4 0.44 1.43 0.76
152 INT200750 Gene_expression of Rho 1 19 0.65 6.52 0.69
153 INT157186 Regulation of Cps1 1 4 0.22 0.54 0.67
154 INT302339 Regulation of Arx 4 1 0.45 1.23 0.66
155 INT35282 Positive_regulation of Chrm4 1 4 0.45 0.81 0.64
156 INT264628 Regulation of GABBR1 1 3 0.26 1.39 0.62
157 INT180244 Positive_regulation of Gad2 1 4 0.49 1.07 0.61
158 INT185240 Binding of Fgf2 2 14 0.37 7.39 0.59
159 INT345991 Negative_regulation of Scamp3 2 1 0.25 0.45 0.58
160 INT196774 Positive_regulation of Gene_expression of Ppp1r1b 1 4 0.31 0.29 0.56
161 INT243864 Gene_expression of DLG4 1 5 0.34 0.22 0.54
162 INT168225 Gene_expression of ge 1 3 0.12 0.09 0.5
163 INT302344 Localization of ge 1 1 0.04 0 0.47
164 INT266864 Gene_expression of Lfp1 2 5 0.14 0.08 0.46
165 INT248207 Positive_regulation of Calb2 1 3 0.20 0.49 0.46
166 INT302337 Positive_regulation of Gene_expression of ge 1 1 0.03 0 0.46
167 INT345989 Regulation of Scamp3 1 1 0.20 0.24 0.46
168 INT207836 Negative_regulation of GAD2 1 2 0.37 0.19 0.45
169 INT228262 Regulation of Cp 3 4 0.38 0.88 0.44
170 INT337348 Regulation of Gene_expression of Fgf2 2 2 0.45 0.54 0.44
171 INT328606 Regulation of Regulation of Slc12a2 1 1 0.10 0 0.42
172 INT302335 Gene_expression of Ebf1 2 1 0.55 0 0.41
173 INT300851 Negative_regulation of Positive_regulation of Fgf2 2 3 0.42 1.01 0.4
174 INT302352 Positive_regulation of Binding of Dlx1 1 1 0.45 0 0.4
175 INT302343 Negative_regulation of Arx 2 1 0.51 0.76 0.4
176 INT302357 Binding of Dlx1 1 1 0.33 0 0.39
177 INT318279 Negative_regulation of SLC32A1 1 1 0.31 0.15 0.38
178 INT318272 Negative_regulation of GPHN 1 1 0.29 0.1 0.37
179 INT243873 Regulation of Gene_expression of GPHN 1 2 0.60 0.62 0.36
180 INT318270 Positive_regulation of Negative_regulation of GABRB3 1 1 0.11 0.09 0.36
181 INT318285 Positive_regulation of Gene_expression of Od 3 1 0.29 0.11 0.36
182 INT23646 Negative_regulation of Scnn1a 1 6 0.57 1.8 0.35
183 INT302351 Regulation of Gene_expression of Arx 1 1 0.45 0 0.35
184 INT243808 Positive_regulation of Transcription of Sh2b2 1 1 0.29 0.86 0.33
185 INT243807 Transcription of Sh2b2 1 1 0.39 0.85 0.33
186 INT318273 Binding of GPHN 1 1 0.22 0.14 0.32
187 INT302349 Regulation of Negative_regulation of Arx 1 1 0.39 0.27 0.31
188 INT318276 Binding of SLC32A1 1 1 0.23 0.13 0.31
189 INT294806 Gene_expression of Dlx5 1 6 0.71 2.07 0.3
190 INT318287 Regulation of Od 2 1 0.16 0 0.3
191 INT302362 Positive_regulation of Positive_regulation of Calb2 1 1 0.11 0.12 0.3
192 INT318274 Regulation of Gene_expression of GAD2 1 1 0.39 0 0.3
193 INT345995 Negative_regulation of Gene_expression of Fgf2 1 1 0.43 0.43 0.29
194 INT320449 Regulation of Negative_regulation of Helt 1 1 0.03 0.55 0.27
195 INT302358 Positive_regulation of Gene_expression of Calb2 1 1 0.12 0.11 0.27
196 INT328605 Negative_regulation of Localization of Car3 1 1 0.20 0 0.26
197 INT345992 Localization of Scamp3 1 1 0.32 0.15 0.26
198 INT302350 Negative_regulation of Gene_expression of Arx 1 1 0.58 0.26 0.26
199 INT318277 Phosphorylation of GABRB3 1 1 0.19 0.45 0.25
200 INT208405 Gene_expression of Scamp3 1 2 0.29 0.87 0.24
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