J:Frontiers in Neuroanatomy

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT112914 Ppp1r1b Negative_regulation of Prkaca 3 1 0.22 0.13 0.86
2 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 2 0.01 0 0.84
3 INT348129 Bgn Regulation of Regulation of Hspg2 1 1 0.00 0.69 0.69
4 INT344115 Positive_regulation of Slc3a1 Positive_regulation of GYPE 1 1 0.01 0 0.58
5 INT344114 Slc3a1 Positive_regulation of GYPE 1 1 0.01 0 0.57
6 INT344104 Binding of Slc6a3 and Obfc1 1 2 0.00 0 0.43
7 INT348136 GYPE Regulation of Gene_expression of Slc3a1 1 1 0.01 0.14 0.4
8 INT344103 Positive_regulation of Drd1a Positive_regulation of Obfc1 1 1 0.00 0 0.38
9 INT337115 Tg(CAG-EGFP)D4Nagy Positive_regulation of Gene_expression of PDYN 1 1 0.04 0.07 0.36
10 INT337114 Tg(CAG-EGFP)D4Nagy Positive_regulation of Gene_expression of TAC1 1 1 0.04 0.07 0.36
11 INT337112 Negative_regulation of Nr1d2-rs2 Positive_regulation of Mapk1 1 1 0.00 0.14 0.33
12 INT337110 Negative_regulation of Nr1d2-rs2 Positive_regulation of Phosphorylation of Hist1h3f 1 1 0.00 0.14 0.33
13 INT337111 Positive_regulation of Nr1d2-rs2 Negative_regulation of Positive_regulation of Mapk1 1 1 0.00 0.15 0.31
14 INT348137 Binding of GYPE and Gpi 1 1 0.01 1.29 0.29
15 INT334737 Binding of Oprd1 and Gpi 1 1 0.01 0.71 0.28
16 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 2 0.11 0.28 0.27
17 INT243802 Binding of co and Decr1 1 1 0.00 0 0.27
18 INT342732 Arrd1 Negative_regulation of da 1 1 0.00 0.72 0.16
19 INT303500 Regulation of Ebf2 Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 1 0.13 0.16 0.05
20 INT243783 FGFR1 Positive_regulation of FGF20 1 1 0.05 0 0.04
21 INT342726 Binding of Laptm5 and Park2 1 1 0.03 0.64 0.04
22 INT342733 Gene_expression of Lrrk2 Positive_regulation of Apaf1 1 1 0.10 0.74 0.03
23 INT342725 Pink1 Positive_regulation of Phosphorylation of Park2 1 1 0.29 0.62 0
24 INT342730 Pink1 Positive_regulation of Phosphorylation of Trap1 1 2 0.17 0.98 0
25 INT342737 Pink1 Positive_regulation of HTRA2 1 1 0.29 0.58 0
26 INT342728 Pink1 Positive_regulation of Trap1 1 2 0.17 0.98 0
27 INT342731 Pink1 Regulation of Localization of Gfm1 1 1 0.00 0.61 0
28 INT342727 Pink1 Positive_regulation of Park2 1 1 0.29 0.62 0
29 INT342736 Pink1 Positive_regulation of Phosphorylation of HTRA2 1 1 0.29 0.58 0
30 INT342729 Pink1 Regulation of Phosphorylation of Trap1 1 1 0.09 0.48 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 11 3083 0.78 894.43 1639.02
2 INT796 Gene_expression of Penk 3 1902 0.78 275.47 1057.59
3 INT3439 Localization of Abat 17 1017 0.78 112.39 727.06
4 INT5202 Positive_regulation of Gene_expression of Fos 5 1163 0.70 319.28 684
5 INT6056 Negative_regulation of Gene_expression of Fos 1 601 0.59 193.05 386.84
6 INT76660 Gene_expression of Trpv1 3 691 0.78 329.46 386.42
7 INT5979 Gene_expression of Oprd1 1 428 0.78 75.64 320.32
8 INT5591 Regulation of Gene_expression of Fos 3 425 0.62 129.06 265.78
9 INT87687 Positive_regulation of Trpv1 2 409 0.70 210.24 257.59
10 INT2909 Positive_regulation of Abat 1 334 0.70 62.1 256.43
11 INT9987 Gene_expression of Abat 4 296 0.78 95.46 226.34
12 INT95787 Positive_regulation of Mapk1 7 568 0.70 226.51 220.94
13 INT6665 Gene_expression of FOS 20 520 0.77 165.31 217.66
14 INT798 Positive_regulation of Gene_expression of Penk 1 394 0.70 78.53 203.07
15 INT2211 Negative_regulation of Abat 2 267 0.59 66.51 200.98
16 INT6354 Localization of Gabrg1 1 321 0.74 41.41 186.74
17 INT3440 Negative_regulation of Localization of Abat 10 221 0.57 33.94 180.36
18 INT1429 Gene_expression of PDYN 1 308 0.78 61.33 175.65
19 INT867 Gene_expression of IFNA1 1 930 0.78 594.85 168.03
20 INT4829 Positive_regulation of Localization of Abat 8 199 0.55 20.91 150.48
21 INT14843 Gene_expression of Gabrg1 7 301 0.77 62.63 139.16
22 INT6323 Positive_regulation of Gabrg1 1 213 0.70 45.08 124.34
23 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 19 1138 0.72 311.58 119.18
24 INT62124 Gene_expression of NOS1 7 444 0.78 218.08 114.85
25 INT48593 Positive_regulation of NOS1 1 420 0.68 226.15 114.71
26 INT7362 Gene_expression of Sst 1 185 0.78 41.73 111.37
27 INT17459 Positive_regulation of Gene_expression of FOS 5 182 0.67 53.45 96.38
28 INT48767 Negative_regulation of NOS1 2 312 0.59 154.25 90.32
29 INT75999 Gene_expression of BDNF 1 344 0.78 114.19 83.12
30 INT62374 Gene_expression of NGF 2 158 0.78 77.87 76.45
31 INT25363 Negative_regulation of Trpv1 1 144 0.59 64.78 75.7
32 INT31774 Positive_regulation of Vta1 1 67 0.44 14.52 71.79
33 INT8962 Gene_expression of Cpe 3 110 0.71 39.67 71.67
34 INT53964 Negative_regulation of Prkaca 1 131 0.58 38.76 69.52
35 INT87686 Positive_regulation of Gene_expression of Trpv1 1 101 0.70 72.41 69.15
36 INT7344 Gene_expression of TAC1 1 132 0.75 35.48 68.26
37 INT5573 Negative_regulation of Gene_expression of Penk 1 113 0.59 21.83 64.66
38 INT96622 Localization of Trpv1 1 110 0.81 59.82 63.25
39 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
40 INT5356 Positive_regulation of FOS 4 153 0.69 54.21 56.74
41 INT17458 Negative_regulation of Gene_expression of FOS 6 98 0.57 36.77 55.69
42 INT7898 Gene_expression of Homer1 1 123 0.78 31.52 53.67
43 INT6034 Binding of Gabrg1 6 115 0.47 17.48 51.92
44 INT5704 Binding of Slc3a1 1 78 0.43 8.52 51.78
45 INT5858 Positive_regulation of Drd1a 14 66 0.69 4.51 51.73
46 INT30170 Gene_expression of Car2 2 330 0.66 77.26 46.76
47 INT8152 Gene_expression of Vta1 4 40 0.58 19.9 46.28
48 INT2783 Gene_expression of Slc3a1 10 86 0.65 8.84 45.4
49 INT17561 Localization of Car2 3 303 0.79 60.95 44.52
50 INT66383 Phosphorylation of Prkaca 1 143 0.80 30.85 43.38
51 INT26788 Gene_expression of Gad1 5 93 0.78 27.05 42.71
52 INT12228 Positive_regulation of Gene_expression of Abat 1 44 0.65 17.51 40.55
53 INT114751 Gene_expression of Mapk1 2 137 0.76 60.14 39.98
54 INT11560 Positive_regulation of CASP3 1 236 0.70 184.33 39.38
55 INT102611 Negative_regulation of Positive_regulation of Mapk1 1 74 0.58 35.57 39.37
56 INT16455 Gene_expression of Drd2 23 116 0.78 22.71 38.47
57 INT14009 Gene_expression of Sst 1 66 0.77 19.6 37.3
58 INT12029 Gene_expression of Car1 5 143 0.67 29.69 36.39
59 INT13501 Binding of Drd2 2 65 0.48 23.76 35.6
60 INT6302 Binding of IFNA1 1 196 0.48 133.85 32.73
61 INT10453 Positive_regulation of Gad1 4 65 0.70 10.75 31.9
62 INT11087 Positive_regulation of Drd2 3 54 0.69 12.4 31.43
63 INT8531 Transcription of PDYN 1 56 0.72 19.51 30.99
64 INT1616 Regulation of Gad1 1 46 0.61 10.2 28.64
65 INT154007 Gene_expression of da 11 46 0.56 15.28 28.22
66 INT2650 Positive_regulation of Slc3a1 17 50 0.57 2.95 27.52
67 INT14575 Positive_regulation of Ppt1 1 60 0.70 9.97 27.4
68 INT9647 Gene_expression of PROC 6 163 0.65 89.76 26.75
69 INT93360 Gene_expression of Slc6a3 6 63 0.78 19.54 26.55
70 INT7899 Positive_regulation of Gene_expression of Homer1 1 41 0.70 7.29 25.98
71 INT48979 Regulation of Gene_expression of FOS 1 52 0.61 14.4 25.95
72 INT80791 Gene_expression of Slc6a3 2 113 0.78 11.89 25.76
73 INT12392 Regulation of Slc3a1 2 45 0.36 7.57 25.66
74 INT13334 Gene_expression of Drd1a 4 43 0.62 7.73 24.43
75 INT4781 Gene_expression of TH 7 68 0.73 26.92 24.01
76 INT13838 Positive_regulation of Drd1a 1 48 0.70 9.83 23.42
77 INT82461 Gene_expression of Gad2 2 40 0.78 19.12 22.79
78 INT17962 Regulation of Car2 1 124 0.41 33.98 22.71
79 INT7715 Regulation of Drd2 2 35 0.62 10.79 22.3
80 INT4890 Gene_expression of Ppt1 1 51 0.77 8.93 21.83
81 INT61825 Negative_regulation of Slc6a3 2 47 0.59 6.52 21.27
82 INT16326 Transcription of Gad1 3 58 0.71 15.78 20.45
83 INT26408 Negative_regulation of da 8 36 0.18 13.46 20.32
84 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 134 0.61 34.87 20.15
85 INT107930 Gene_expression of Slc17a7 3 39 0.78 6.53 18.86
86 INT90937 Negative_regulation of Gene_expression of Trpv1 1 34 0.59 22.74 18.12
87 INT5198 Negative_regulation of Vta1 1 21 0.59 4.78 18.07
88 INT6461 Gene_expression of Npr1 1 35 0.75 10.38 17.58
89 INT51779 Gene_expression of Drd1a 5 46 0.66 11.18 17.51
90 INT34057 Negative_regulation of Gene_expression of IFNA1 1 65 0.58 43.46 17.25
91 INT7020 Negative_regulation of Drd1a 1 25 0.57 1.84 17.1
92 INT65214 Binding of Slc6a3 3 54 0.48 4.77 16.79
93 INT13989 Negative_regulation of Slc3a1 4 27 0.24 5.34 16.76
94 INT107928 Gene_expression of Slc17a6 1 34 0.76 3.76 16.64
95 INT112908 Phosphorylation of Ppp1r1b 4 65 0.77 1.27 16.42
96 INT108588 Gene_expression of CASP3 1 126 0.78 84.49 16.2
97 INT13716 Positive_regulation of TH 1 33 0.68 19.11 16
98 INT50618 Gene_expression of Dio1 5 48 0.74 17.37 15.91
99 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 3 95 0.43 24.83 15.69
100 INT7952 Localization of Slc3a1 2 32 0.81 1.28 15.69
101 INT5859 Positive_regulation of Positive_regulation of Drd1a 5 20 0.55 2.05 15.61
102 INT22143 Gene_expression of Gad1 1 35 0.76 14.4 15.4
103 INT54356 Regulation of Slc6a3 2 48 0.58 5.86 15.24
104 INT26729 Negative_regulation of Drd2 1 28 0.55 9.32 15.17
105 INT28510 Positive_regulation of Gpi 12 21 0.68 6.75 14.27
106 INT6869 Positive_regulation of Car3 1 34 0.61 5.15 14.21
107 INT33095 Localization of da 7 16 0.62 3.76 13.92
108 INT28314 Negative_regulation of Gene_expression of Gabrg1 1 29 0.44 12.56 13.8
109 INT2038 Localization of Esr1 2 104 0.79 40.12 13.27
110 INT15246 Regulation of FOS 2 32 0.60 15.34 12.94
111 INT90909 Negative_regulation of Gene_expression of NOS1 1 44 0.55 23.83 12.47
112 INT32336 Positive_regulation of da 5 16 0.42 4.69 12.38
113 INT27507 Positive_regulation of Dio1 3 23 0.44 3.43 12.11
114 INT116433 Gene_expression of CYBB 1 93 0.70 50.44 11.91
115 INT7682 Binding of Drd1a 1 22 0.48 1.8 11.83
116 INT7903 Positive_regulation of Fosl1 1 21 0.70 3.53 11.36
117 INT6748 Regulation of Dio1 1 15 0.45 2.63 11.18
118 INT84077 Gene_expression of Hmox2 1 18 0.77 6.41 10.66
119 INT52657 Phosphorylation of Fos 1 20 0.80 6.36 10.64
120 INT127123 Positive_regulation of Snca 1 35 0.70 14.76 10.1
121 INT98130 Positive_regulation of CASP8 4 79 0.67 65.29 10.08
122 INT75955 Gene_expression of Drd3 2 19 0.77 4.39 10.07
123 INT32239 Gene_expression of Car3 4 38 0.67 6.86 9.76
124 INT66382 Positive_regulation of Phosphorylation of Prkaca 1 33 0.49 7.05 9.69
125 INT57039 Positive_regulation of Gene_expression of Drd2 3 16 0.50 1.98 9.48
126 INT1129 Binding of Car2 1 69 0.35 14.01 9.2
127 INT48978 Negative_regulation of FOS 4 41 0.57 11.94 9.14
128 INT1168 Binding of PROC 1 62 0.38 44.15 9.04
129 INT26789 Positive_regulation of Gene_expression of Gad1 4 22 0.70 7.39 9.02
130 INT34544 Gene_expression of L1cam 1 43 0.77 5.3 8.89
131 INT220 Negative_regulation of Ddc 1 16 0.59 2.94 8.66
132 INT26795 Gene_expression of Mtpn 2 44 0.62 27.66 8.62
133 INT939 Gene_expression of PAEP 1 86 0.77 31.02 8.59
134 INT15308 Localization of Chat 1 29 0.81 2.35 8.47
135 INT16735 Localization of Drd1a 3 11 0.61 0.35 8.42
136 INT48908 Transcription of NOS1 1 27 0.55 13.46 8.39
137 INT146343 Regulation of Slc6a3 2 17 0.60 7.33 8.27
138 INT22056 Positive_regulation of CYBB 1 88 0.68 32.13 7.95
139 INT12028 Regulation of Car1 2 28 0.43 9.01 7.84
140 INT73595 Positive_regulation of BAX 1 61 0.61 56.97 7.82
141 INT52465 Negative_regulation of Dio1 1 17 0.58 4.45 7.76
142 INT18524 Regulation of Gene_expression of IFNA1 1 37 0.44 18.79 7.62
143 INT76892 Gene_expression of FGFR1 2 45 0.69 23.6 7.56
144 INT43901 Negative_regulation of Ptpn2 1 65 0.37 56.32 7.48
145 INT161107 Gene_expression of Ptpn2 2 58 0.58 49.92 7.4
146 INT75063 Regulation of Gene_expression of Drd2 3 10 0.62 2.82 7.38
147 INT120401 Positive_regulation of PIK3CD 1 33 0.45 14.89 7.37
148 INT73760 Transcription of Drd2 2 14 0.72 2.11 7.19
149 INT5774 Regulation of Ppt1 1 22 0.60 4.97 7.1
150 INT60196 Binding of FOS 1 33 0.47 13.11 6.95
151 INT102749 Positive_regulation of Positive_regulation of CASP3 1 32 0.67 26.07 6.93
152 INT62691 Transcription of Cpe 1 11 0.40 3.5 6.66
153 INT158280 Positive_regulation of Gene_expression of da 2 9 0.42 2.29 6.64
154 INT25022 Binding of PAEP 1 66 0.42 22.83 6.59
155 INT48239 Binding of Gtf3a 1 52 0.33 23.14 6.45
156 INT5847 Transcription of FOS 4 31 0.69 11.11 6.41
157 INT86772 Localization of Drd2 7 14 0.80 1.93 6.17
158 INT223568 Gene_expression of GYPE 15 21 0.65 5.83 6.12
159 INT21552 Regulation of Drd1a 1 10 0.57 3.7 6.05
160 INT48911 Binding of NOS1 2 24 0.40 11.21 5.89
161 INT147263 Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 51 0.53 15.32 5.86
162 INT75978 Transcription of Gad2 2 11 0.69 2.28 5.68
163 INT104673 Positive_regulation of Obfc1 13 10 0.41 4.26 5.61
164 INT18366 Negative_regulation of Positive_regulation of Drd1a 4 6 0.42 0.49 5.54
165 INT35248 Gene_expression of Gpi 10 14 0.51 2.38 5.49
166 INT151387 Gene_expression of Cav3 1 14 0.78 4 5.31
167 INT74051 Negative_regulation of Localization of Car2 1 27 0.38 9.58 5.1
168 INT23284 Negative_regulation of Gpi 7 5 0.58 1.84 4.96
169 INT25831 Gene_expression of NR4A2 1 20 0.74 2.73 4.92
170 INT204971 Gene_expression of Pink1 1 42 0.77 23.95 4.75
171 INT66388 Positive_regulation of Transcription of Gad1 1 14 0.67 2.45 4.67
172 INT203443 Gene_expression of Isl1 12 27 0.67 11.12 4.65
173 INT24011 Binding of Drd3 1 13 0.47 3.03 4.64
174 INT138348 Positive_regulation of Phosphorylation of Ppp1r1b 1 16 0.56 1.4 4.63
175 INT2836 Positive_regulation of PAEP 2 51 0.67 26.69 4.57
176 INT54911 Localization of FOS 1 20 0.78 3.27 4.56
177 INT48567 Transcription of Drd1a 1 7 0.51 2.44 4.54
178 INT113107 Phosphorylation of Hist1h3f 2 21 0.51 8.01 4.45
179 INT86516 Positive_regulation of Hmox2 1 6 0.69 3.22 4.39
180 INT16450 Positive_regulation of Positive_regulation of Slc3a1 1 9 0.41 0 4.33
181 INT63740 Positive_regulation of Gad2 1 11 0.66 0.78 4.32
182 INT76467 Regulation of Gene_expression of Car2 1 41 0.37 12.88 4.21
183 INT113137 Positive_regulation of Ppp1r1b 1 14 0.65 0.89 4.21
184 INT43903 Regulation of Ptpn2 1 21 0.41 15.51 4.08
185 INT184913 Negative_regulation of Gene_expression of da 1 7 0.18 2.48 4.05
186 INT125836 Gene_expression of Slc18a2 1 8 0.72 2.65 4.03
187 INT196736 Gene_expression of Ppp1r1b 2 24 0.55 2.01 3.99
188 INT88805 Protein_catabolism of CASP3 1 24 0.86 18.38 3.7
189 INT75869 Gene_expression of Acsl1 1 24 0.45 27.76 3.66
190 INT5579 Binding of da 5 5 0.31 3.14 3.56
191 INT41541 Regulation of Gene_expression of Car1 2 9 0.41 3.82 3.52
192 INT124579 Localization of BAX 1 35 0.78 30.31 3.43
193 INT76869 Localization of PAEP 1 15 0.73 6.57 3.36
194 INT137679 Localization of Gfm1 1 18 0.08 9.58 3.24
195 INT109095 Binding of Drd4 1 7 0.40 3.6 3.18
196 INT2837 Regulation of PAEP 1 17 0.53 7.84 3.17
197 INT112907 Regulation of Phosphorylation of Ppp1r1b 1 11 0.21 0.06 3.15
198 INT114622 Negative_regulation of Localization of da 1 4 0.33 0.95 3.1
199 INT149795 Gene_expression of Ddc 1 8 0.73 1.5 3.06
200 INT88273 Gene_expression of Drd4 1 6 0.54 1.84 3.01
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