J:Gastroenterology

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT13966 Calca Positive_regulation of Localization of Sst 5 1 0.49 0.75 3.91
2 INT13979 Gast Positive_regulation of Localization of Sst 3 1 0.69 0.05 1.75
3 INT30872 Abat Positive_regulation of Localization of Gast 1 2 0.26 0 1.43
4 INT18589 Gast Regulation of Localization of Sst 1 2 0.61 0.15 1.37
5 INT30871 Abat Regulation of Localization of Sst 1 2 0.13 0 1.17
6 INT142847 IRF6 Positive_regulation of IL6 5 1 0.07 1.09 0.73
7 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 1 0.19 1.38 0.58
8 INT2462 CCK Regulation of Localization of GAST 1 1 0.09 0.21 0.51
9 INT15273 Calca Regulation of Tacr1 1 1 0.22 0 0.5
10 INT67193 IL8 Regulation of Localization of SST 1 1 0.00 0.66 0.28
11 INT67199 Tgfa Regulation of Localization of IL8 1 1 0.00 0.66 0.28
12 INT80873 Positive_regulation of Nfkb1 Positive_regulation of Protein_catabolism of Nfkbia 2 1 0.01 0.58 0.27
13 INT67198 IL8 Regulation of Tgfa 1 1 0.00 0.65 0.27
14 INT5645 Sult2a1 Positive_regulation of Positive_regulation of IGKV2-29 1 2 0.00 0.39 0.22
15 INT5646 Sult2a1 Positive_regulation of IGKV2-29 1 2 0.00 0.39 0.22
16 INT49154 Binding of CALCA and Gast 1 1 0.15 0 0.2
17 INT24759 Sct Positive_regulation of Gene_expression of Gast 1 1 0.08 0.63 0.18
18 INT47584 Oxt Positive_regulation of Vip 1 1 0.02 0 0.06
19 INT126931 Slc8a2 Positive_regulation of Localization of Il10 1 1 0.12 0.08 0
20 INT93806 Bgn Positive_regulation of Localization of Calca 1 1 0.11 0 0
21 INT81588 Positive_regulation of Tnf Positive_regulation of RFFL 1 1 0.00 0 0
22 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 1 0.51 0.12 0
23 INT20322 Binding of CYP1A2 and CYP26A1 1 1 0.00 0 0
24 INT81587 Tnf Positive_regulation of RFFL 1 1 0.00 0 0
25 INT20325 Binding of CYP2D6 and CYP21A2 1 1 0.00 0 0
26 INT20326 Binding of CYP1A2 and CYP21A2 1 1 0.01 0 0
27 INT105613 Binding of Abpa and Spink1 1 1 0.01 0.06 0
28 INT20324 Binding of CYP2D6 and CYP26A1 1 1 0.00 0 0
29 INT126934 Ltb4r Positive_regulation of Positive_regulation of Trpv1 1 1 0.05 0 0
30 INT126932 Slc8a2 Positive_regulation of Il10 1 1 0.09 0.06 0
31 INT141576 Slc6a14 Positive_regulation of Gene_expression of Tnf 1 1 0.05 0.07 0
32 INT20321 Binding of CYP2E1 and CYP21A2 1 1 0.00 0 0
33 INT136915 RYBP Positive_regulation of Localization of Bax 1 1 0.01 0.12 0
34 INT20323 Binding of CYP2E1 and CYP26A1 1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 5 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 15 2008 0.81 518.3 1408.65
3 INT6483 Gene_expression of TNF 7 3152 0.78 2515.62 929.82
4 INT1912 Gene_expression of Calca 4 1152 0.78 453.25 739.84
5 INT3439 Localization of Abat 2 1017 0.78 112.39 727.06
6 INT5202 Positive_regulation of Gene_expression of Fos 1 1163 0.70 319.28 684
7 INT292 Localization of Penk 2 876 0.81 88.44 669.14
8 INT58061 Gene_expression of Trpv1 6 1117 0.78 451.54 637.59
9 INT2543 Positive_regulation of Calca 3 787 0.70 331.13 592.08
10 INT443 Localization of POMC 5 1020 0.81 284.52 443.17
11 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
12 INT4758 Positive_regulation of Localization of Calca 4 557 0.70 138.55 411.04
13 INT64202 Positive_regulation of Trpv1 2 643 0.70 249.66 397.42
14 INT467 Gene_expression of POMC 7 1048 0.78 332.8 394.16
15 INT1395 Negative_regulation of Penk 2 537 0.59 87.33 389.81
16 INT6056 Negative_regulation of Gene_expression of Fos 1 601 0.59 193.05 386.84
17 INT287 Localization of Cck 8 518 0.81 86.84 364.04
18 INT720 Positive_regulation of POMC 6 807 0.70 237.37 353.83
19 INT34869 Negative_regulation of PTGS2 4 778 0.59 366.76 319.85
20 INT5680 Gene_expression of Ngf 6 530 0.78 264.29 310.56
21 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
22 INT9158 Gene_expression of Tnf 2 722 0.78 522.01 277.68
23 INT2365 Positive_regulation of Cck 12 354 0.70 87.8 277.41
24 INT49750 Negative_regulation of CPOX 2 735 0.58 360.06 274.19
25 INT6852 Localization of TNF 2 883 0.81 705.95 270.84
26 INT10832 Gene_expression of IL8 1 1050 0.78 698.72 270
27 INT3948 Regulation of Cck 4 291 0.62 58.07 255.88
28 INT1005 Localization of Sst 29 385 0.81 26.31 244.56
29 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
30 INT1902 Gene_expression of Cck 6 348 0.78 70.33 241.92
31 INT11377 Positive_regulation of Ngf 2 331 0.70 206.5 238
32 INT626 Localization of CALCA 1 289 0.81 125.39 221.15
33 INT1308 Localization of Pomc 3 457 0.81 66.83 217.5
34 INT6293 Gene_expression of Oprm1 1 312 0.78 48.73 215.61
35 INT767 Localization of Gnrhr 1 565 0.80 106.68 214.57
36 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
37 INT63934 Phosphorylation of Ephb1 1 377 0.82 150.52 188.66
38 INT6354 Localization of Gabrg1 2 321 0.74 41.41 186.74
39 INT1652 Regulation of Pomc 1 387 0.62 61.01 186.51
40 INT10194 Positive_regulation of IL6 2 702 0.70 600.62 183.38
41 INT1429 Gene_expression of PDYN 3 308 0.78 61.33 175.65
42 INT943 Negative_regulation of Cck 2 205 0.59 38.42 174.78
43 INT4937 Negative_regulation of Oprd1 2 224 0.59 44.51 171.11
44 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
45 INT4768 Positive_regulation of OPRM1 1 212 0.70 31.09 164.28
46 INT2366 Binding of Cck 4 192 0.48 30.64 163.46
47 INT5513 Negative_regulation of Pomc 1 295 0.59 60.9 158.63
48 INT768 Positive_regulation of Oprl1 1 179 0.70 40.05 156.93
49 INT2640 Gene_expression of Pomc 2 424 0.78 120.72 155.37
50 INT6042 Binding of Oprm1 1 248 0.48 31.77 154.34
51 INT4829 Positive_regulation of Localization of Abat 1 199 0.55 20.91 150.48
52 INT2867 Gene_expression of CALCA 1 247 0.78 78.78 138.47
53 INT60126 Regulation of Trpv1 1 186 0.62 85.53 133.4
54 INT695 Binding of POMC 1 304 0.48 56.66 126.85
55 INT65054 Positive_regulation of Nfkb1 2 285 0.70 149.33 126.73
56 INT5931 Regulation of Oprm1 1 149 0.62 18.15 125.93
57 INT4824 Positive_regulation of Tacr1 4 169 0.70 66.1 123.46
58 INT6128 Positive_regulation of Localization of POMC 1 256 0.70 68.77 121.64
59 INT64201 Negative_regulation of Trpv1 1 203 0.59 79.18 119.75
60 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
61 INT50674 Gene_expression of PTGS2 1 459 0.78 253.33 118.51
62 INT12339 Localization of IL8 1 437 0.81 251.87 117.39
63 INT1438 Localization of Pomc 1 360 0.81 101.26 116.47
64 INT90 Localization of Gast 32 400 0.81 137.67 113
65 INT7362 Gene_expression of Sst 1 185 0.78 41.73 111.37
66 INT47243 Gene_expression of Prkcg 5 195 0.78 58.05 108.44
67 INT9012 Localization of Vip 12 283 0.81 31.71 106.16
68 INT89054 Positive_regulation of Gene_expression of Trpv1 2 156 0.70 90.78 102.03
69 INT5906 Negative_regulation of Oprm1 1 125 0.59 19.58 101.57
70 INT5587 Regulation of Fos 1 191 0.62 40.81 99.7
71 INT293 Protein_catabolism of Penk 1 161 1.00 11.71 98.45
72 INT4860 Positive_regulation of CALCA 3 148 0.00 73.35 97.61
73 INT940 Negative_regulation of Ptgs1 2 219 0.59 104.34 95.97
74 INT74058 Gene_expression of Nos1 1 260 0.78 80.04 95.71
75 INT1004 Regulation of Sst 8 140 0.62 18.52 94.84
76 INT2862 Positive_regulation of Localization of Cck 2 108 0.70 20.75 94.25
77 INT18755 Positive_regulation of Rvm 1 79 0.60 60 92.93
78 INT9516 Negative_regulation of Gabrg1 1 149 0.53 27.83 91.02
79 INT10166 Localization of Tnf 2 237 0.81 153.95 88.64
80 INT1635 Gene_expression of Vip 2 245 0.78 53.36 88.13
81 INT3441 Regulation of Localization of Abat 1 117 0.38 8.67 87.59
82 INT4631 Positive_regulation of Sst 8 127 0.70 17.37 83.29
83 INT16254 Positive_regulation of Gene_expression of Ngf 2 144 0.70 80.61 82.08
84 INT8650 Gene_expression of Gal 2 152 0.78 61.97 81.72
85 INT48406 Gene_expression of Icam1 7 277 0.78 238.28 81.71
86 INT403 Localization of Trh 3 241 0.81 28.55 81.45
87 INT55944 Positive_regulation of Cpox 3 214 0.57 105.14 81.4
88 INT2431 Positive_regulation of Mpo 2 275 0.70 211.99 78.47
89 INT2155 Negative_regulation of Sst 5 111 0.59 16.58 77.74
90 INT9236 Regulation of Gene_expression of TNF 2 204 0.62 162.66 72.99
91 INT3034 Localization of Ngf 1 126 0.81 50.81 72.84
92 INT8346 Gene_expression of Qrfp 1 136 0.70 19.49 70.21
93 INT1376 Binding of Trh 1 121 0.48 20 69.86
94 INT7534 Gene_expression of Ifng 2 193 0.78 111.02 68.6
95 INT15613 Negative_regulation of Ptgs2 3 160 0.59 71.08 65.08
96 INT7280 Positive_regulation of Localization of Sst 10 97 0.70 5.64 63.37
97 INT217 Negative_regulation of Th 1 134 0.59 26.83 62.63
98 INT46 Localization of Ren 1 233 0.81 46.15 62.44
99 INT6761 Binding of CALCA 3 100 0.48 26.71 62.05
100 INT9196 Gene_expression of PTGS1 1 215 0.77 96.99 60.5
101 INT17564 Gene_expression of Gpt 2 322 0.75 208.51 60.36
102 INT14740 Gene_expression of TGFB1 11 272 0.78 168.48 60.18
103 INT1536 Negative_regulation of NA 1 244 0.55 52.67 59.79
104 INT5016 Negative_regulation of Crh 1 129 0.59 36.74 59.28
105 INT49170 Negative_regulation of Nos1 1 116 0.59 60.66 58.87
106 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
107 INT5017 Negative_regulation of Tacr1 1 76 0.58 17 57.07
108 INT52800 Negative_regulation of Gene_expression of Tnf 1 142 0.59 92.27 55.47
109 INT4241 Regulation of CALCA 2 87 0.62 28.19 55.29
110 INT771 Regulation of Nts 1 93 0.61 13.13 53.57
111 INT5759 Positive_regulation of Ptgs1 1 127 0.69 53.45 53.04
112 INT52611 Negative_regulation of Ptgs2 4 142 0.59 66.31 52.71
113 INT22112 Positive_regulation of Localization of TNF 1 164 0.70 115.66 52.18
114 INT72182 Gene_expression of Mcpt1 6 167 0.75 123.7 52.15
115 INT5118 Regulation of SST 1 97 0.62 34.35 51.74
116 INT8490 Negative_regulation of CALCA 1 87 0.59 29.73 51.34
117 INT5098 Negative_regulation of Localization of Sst 6 70 0.58 3.56 51.17
118 INT2604 Positive_regulation of Got1 3 223 0.70 154.78 49.51
119 INT16850 Negative_regulation of Localization of Gabrg1 1 73 0.51 8.28 47.89
120 INT671 Positive_regulation of Cea 1 221 0.69 164.5 47.79
121 INT2463 Localization of CCK 3 101 0.81 37.54 47.59
122 INT5337 Negative_regulation of Npy 1 87 0.59 19.6 46.75
123 INT2406 Gene_expression of CCK 2 85 0.78 28.04 46.67
124 INT4776 Localization of TAC1 1 82 0.78 16.89 45.21
125 INT14853 Negative_regulation of Tac1 1 80 0.59 30.87 45.06
126 INT89 Positive_regulation of Gast 18 187 0.70 80.49 42.07
127 INT2364 Localization of Sct 3 134 0.80 26.21 41.47
128 INT30 Gene_expression of Gast 9 158 0.78 99 41.45
129 INT4862 Localization of PENK 1 62 0.81 11.57 40.28
130 INT2429 Negative_regulation of Mpo 1 128 0.59 93.76 39.57
131 INT6357 Positive_regulation of Localization of Gabrg1 1 53 0.41 7.03 39.21
132 INT1931 Positive_regulation of Gene_expression of POMC 1 116 0.70 37.26 38.67
133 INT55135 Positive_regulation of Gene_expression of PTGS2 1 137 0.70 80.32 38.46
134 INT4449 Positive_regulation of NA 1 179 0.55 40.26 37.82
135 INT5039 Positive_regulation of Gal 1 67 0.68 27.97 37.36
136 INT8837 Positive_regulation of TAC1 1 59 0.67 21.94 35.97
137 INT7282 Regulation of Localization of Sst 4 58 0.62 1.92 34.83
138 INT76531 Transcription of Trpv1 1 62 0.72 23.69 34.77
139 INT692 Negative_regulation of SST 1 72 0.59 28.68 34.52
140 INT946 Negative_regulation of Nts 1 60 0.57 4.61 34.44
141 INT96624 Positive_regulation of Positive_regulation of Trpv1 1 62 0.70 20.5 34.28
142 INT49214 Gene_expression of Cd4 1 269 0.78 154.22 34.05
143 INT64171 Regulation of CPOX 1 109 0.36 55.36 32.96
144 INT51698 Positive_regulation of Gene_expression of Prkcg 2 44 0.68 14.02 32.9
145 INT6302 Binding of IFNA1 1 196 0.48 133.85 32.73
146 INT691 Binding of SST 1 67 0.48 24.66 32.67
147 INT3117 Regulation of Oxt 1 103 0.61 17.93 32.28
148 INT13897 Localization of Sst 7 65 0.81 14.91 32.24
149 INT6053 Transcription of Fos 2 107 0.72 20.97 31.88
150 INT5418 Negative_regulation of Alox5 1 108 0.57 42.09 31.17
151 INT8027 Regulation of Gene_expression of Ngf 2 34 0.62 26.32 31.16
152 INT6277 Positive_regulation of Gene_expression of Pomc 2 76 0.70 21.45 31.09
153 INT15347 Positive_regulation of Localization of Pomc 1 81 0.70 28.1 31.01
154 INT2278 Regulation of Localization of Gast 7 81 0.62 16.93 30.64
155 INT1179 Negative_regulation of Ace 2 157 0.59 67.03 30.46
156 INT90792 Localization of Il10 2 144 0.80 87.88 30.03
157 INT52690 Positive_regulation of Ptgs2 1 65 0.68 39.51 30.02
158 INT28 Regulation of Gast 7 106 0.62 26.37 29.85
159 INT91 Positive_regulation of Localization of Gast 12 96 0.70 23.22 29.36
160 INT2389 Regulation of PTGS1 1 86 0.61 31.23 28.95
161 INT84494 Negative_regulation of Phosphorylation of Ephb1 1 44 0.59 22.34 28.68
162 INT16814 Negative_regulation of COX5A 1 74 0.57 33.72 28.63
163 INT4861 Localization of GRP 5 84 0.80 8.26 28.03
164 INT11361 Gene_expression of SERPINE1 1 183 0.78 136.45 27.97
165 INT48202 Gene_expression of Tgfb1 1 146 0.78 89.93 27.76
166 INT8698 Localization of Nka1 3 50 0.78 5.8 27.67
167 INT9296 Negative_regulation of PLEK 2 100 0.57 36.65 27.52
168 INT7894 Negative_regulation of Vip 2 59 0.59 11.76 27.36
169 INT703 Positive_regulation of Pth 1 177 0.70 127.09 27.26
170 INT50490 Regulation of PTGS2 1 80 0.48 39.51 25.85
171 INT47075 Positive_regulation of Ptger2 1 142 0.70 78.55 25.47
172 INT93626 Gene_expression of Fasl 1 118 0.75 115.24 25.11
173 INT29 Negative_regulation of Gast 1 74 0.59 24.85 24.96
174 INT288 Positive_regulation of Sct 6 88 0.70 32.83 24.5
175 INT10240 Gene_expression of Gap43 2 58 0.78 22.11 24.45
176 INT58301 Positive_regulation of Mpo 1 87 0.70 80.19 23.99
177 INT16431 Localization of Lnpep 1 62 0.70 6.28 23.94
178 INT7383 Localization of VIP 1 53 0.81 17.7 22.65
179 INT8699 Gene_expression of Nka1 3 45 0.67 6.41 22.56
180 INT14733 Positive_regulation of Gene_expression of TGFB1 5 71 0.69 49.89 22.2
181 INT48407 Positive_regulation of Gene_expression of Icam1 5 61 0.70 57.91 21.54
182 INT74059 Positive_regulation of Gene_expression of Nos1 1 55 0.70 11.5 21.39
183 INT5040 Regulation of Gal 1 42 0.60 12.72 21.18
184 INT90849 Gene_expression of F2rl1 1 55 0.78 31.31 20.65
185 INT14701 Negative_regulation of IFNA1 1 118 0.54 84.19 20.08
186 INT7253 Negative_regulation of Localization of Gast 5 70 0.59 21.06 20.06
187 INT12243 Positive_regulation of PRSS1 1 91 0.70 52.87 19.48
188 INT66751 Negative_regulation of Localization of Tnf 1 48 0.59 26 19.36
189 INT11243 Localization of NPY 1 33 0.78 11.18 19.24
190 INT11509 Localization of Slc4a4 7 66 0.67 2.34 19.05
191 INT9230 Gene_expression of Htr3a 6 43 0.78 10.54 18.81
192 INT101988 Positive_regulation of GDF15 1 71 0.69 51.03 18.56
193 INT14114 Binding of Adra2a 1 30 0.48 4.24 18.53
194 INT35086 Positive_regulation of Gene_expression of Ifng 4 40 0.69 22.55 18.35
195 INT28215 Gene_expression of CDKN1A 9 196 0.76 113.9 18.3
196 INT18457 Transcription of Sst 1 25 0.69 4.28 18.25
197 INT11525 Negative_regulation of Localization of Vip 1 42 0.49 6.91 18.04
198 INT12081 Localization of TGFB1 1 64 0.81 35.4 17.47
199 INT29555 Positive_regulation of CALM1 1 58 0.69 14.09 17.37
200 INT12875 Regulation of Adra2a 1 26 0.45 7.51 17.35
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