J:Gen. Comp. Endocrinol.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT10268 Binding of PDYN and POMC 11 2 0.39 0.08 10.36
2 INT16891 GHRH Regulation of GH1 5 1 0.37 1.94 1.82
3 INT51749 Penk Negative_regulation of Localization of RMRP 1 1 0.01 0.08 0.59
4 INT41192 Trh Positive_regulation of Localization of POMC 1 2 0.04 0 0.29
5 INT124236 Crh Regulation of Localization of BTF3 1 2 0.00 0.32 0.18
6 INT124235 Crh Regulation of BTF3 1 1 0.00 0.16 0.09
7 INT39202 TRH Regulation of GH1 1 1 0.22 0 0
8 INT39205 TRH Positive_regulation of GH1 1 1 0.44 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 6 1902 0.78 275.47 1057.59
2 INT158 Localization of Prl 6 2431 0.81 378.96 952.2
3 INT292 Localization of Penk 1 876 0.81 88.44 669.14
4 INT155 Positive_regulation of Prl 8 1233 0.70 317.93 457.82
5 INT443 Localization of POMC 5 1020 0.81 284.52 443.17
6 INT467 Gene_expression of POMC 23 1048 0.78 332.8 394.16
7 INT1395 Negative_regulation of Penk 1 537 0.59 87.33 389.81
8 INT157 Positive_regulation of Localization of Prl 1 790 0.70 104.54 374.78
9 INT439 Localization of Gnrh1 1 976 0.81 100.96 363.25
10 INT720 Positive_regulation of POMC 6 807 0.70 237.37 353.83
11 INT162 Regulation of Prl 3 794 0.62 165.01 322.24
12 INT161 Regulation of Localization of Prl 4 615 0.62 65.37 298.66
13 INT886 Gene_expression of Pomc 2 676 0.78 129.87 295.98
14 INT1893 Localization of Gh 7 1041 0.79 340.23 256.58
15 INT3948 Regulation of Cck 1 291 0.62 58.07 255.88
16 INT5501 Regulation of Oprd1 2 283 0.62 55.1 249.9
17 INT738 Regulation of POMC 3 459 0.62 111.19 243.74
18 INT1902 Gene_expression of Cck 1 348 0.78 70.33 241.92
19 INT1562 Localization of Crh 5 499 0.81 126.74 236.68
20 INT2651 Positive_regulation of Pomc 5 403 0.70 95.72 206.24
21 INT798 Positive_regulation of Gene_expression of Penk 2 394 0.70 78.53 203.07
22 INT528 Gene_expression of Prl 1 693 0.78 217.18 192.2
23 INT1429 Gene_expression of PDYN 7 308 0.78 61.33 175.65
24 INT438 Gene_expression of Crh 2 376 0.78 159.11 169.17
25 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
26 INT5127 Localization of Lhb 11 488 0.80 50.48 162.66
27 INT3448 Positive_regulation of Gh 5 521 0.69 180.03 161.18
28 INT5513 Negative_regulation of Pomc 2 295 0.59 60.9 158.63
29 INT2640 Gene_expression of Pomc 4 424 0.78 120.72 155.37
30 INT4740 Gene_expression of Th 1 298 0.78 61.27 154.03
31 INT1273 Gene_expression of Avp 5 356 0.78 90.56 138.7
32 INT1614 Gene_expression of Oprl1 1 164 0.78 31.43 127.74
33 INT695 Binding of POMC 4 304 0.48 56.66 126.85
34 INT252 Localization of GH1 3 529 0.80 227.4 122.05
35 INT7395 Localization of GNRH1 14 399 0.81 62.88 117.68
36 INT1438 Localization of Pomc 2 360 0.81 101.26 116.47
37 INT1793 Localization of CGA 3 379 0.81 67.38 114.69
38 INT1530 Regulation of Gh 8 382 0.61 115.96 112.47
39 INT915 Positive_regulation of PRL 1 342 0.70 141.96 104.31
40 INT5940 Negative_regulation of Avp 2 236 0.59 67.86 101.2
41 INT5865 Positive_regulation of Localization of Gh 1 282 0.69 84.86 93.5
42 INT203 Positive_regulation of Pomc 1 257 0.70 90.56 92.84
43 INT214 Localization of AVP 2 370 0.81 208.51 91.09
44 INT4798 Gene_expression of Nts 1 169 0.77 29.56 86.04
45 INT914 Positive_regulation of GH1 8 292 0.69 100.7 84.91
46 INT339 Regulation of Trh 1 156 0.62 39.27 83.55
47 INT403 Localization of Trh 2 241 0.81 28.55 81.45
48 INT1498 Gene_expression of Gh 3 521 0.75 220.84 81.16
49 INT1497 Negative_regulation of Gh 4 415 0.59 192.95 74.71
50 INT5128 Positive_regulation of Lhb 4 232 0.69 44.23 71.26
51 INT2055 Regulation of Gnrh1 1 185 0.62 23.65 71.26
52 INT1377 Positive_regulation of Trh 1 172 0.70 40.55 69.83
53 INT253 Regulation of PRL 1 184 0.62 47.27 65.79
54 INT1536 Negative_regulation of NA 1 244 0.55 52.67 59.79
55 INT3161 Regulation of Localization of Gh 5 163 0.61 35.43 59.45
56 INT1794 Regulation of Localization of CGA 2 136 0.57 13.39 59.07
57 INT5710 Negative_regulation of Localization of Lhb 4 146 0.57 20.51 58.33
58 INT1510 Binding of PDYN 1 94 0.48 4.68 56.44
59 INT5453 Regulation of Localization of POMC 1 114 0.62 20.56 56.34
60 INT1463 Binding of Pomc 2 129 0.48 15.89 56.27
61 INT5034 Negative_regulation of Insr 1 100 0.55 28.08 54.5
62 INT5509 Positive_regulation of Localization of Crh 1 91 0.70 30.65 53.92
63 INT771 Regulation of Nts 2 93 0.61 13.13 53.57
64 INT249 Localization of GHRH 9 215 0.80 78.02 51.87
65 INT921 Regulation of GH1 2 172 0.60 52.88 51.04
66 INT6299 Regulation of Localization of Lhb 3 104 0.61 8.98 48.79
67 INT531 Gene_expression of GH1 2 376 0.75 193.45 46.24
68 INT2262 Negative_regulation of Lhb 5 142 0.59 25.47 44.81
69 INT8824 Regulation of Vip 1 95 0.62 15.7 43.63
70 INT1894 Negative_regulation of Localization of Gh 2 168 0.58 64.12 43.56
71 INT1295 Binding of Pomc 1 85 0.48 12.92 42.8
72 INT64440 Gene_expression of Pnoc 1 66 0.78 13.61 41.76
73 INT957 Positive_regulation of GHRH 3 136 0.70 36.84 40.52
74 INT14009 Gene_expression of Sst 1 66 0.77 19.6 37.3
75 INT5711 Positive_regulation of Localization of Lhb 5 90 0.70 10.92 36.76
76 INT7675 Gene_expression of ENG 2 146 0.77 45.35 34.6
77 INT11764 Positive_regulation of ENG 1 78 0.61 27.65 33.69
78 INT248 Positive_regulation of Localization of GH1 2 137 0.69 49.25 32.92
79 INT5868 Positive_regulation of GNRH1 2 122 0.69 20.96 32.8
80 INT985 Negative_regulation of GH1 3 213 0.57 89.53 32.39
81 INT7396 Regulation of Localization of GNRH1 7 81 0.62 6.57 31.31
82 INT6277 Positive_regulation of Gene_expression of Pomc 1 76 0.70 21.45 31.09
83 INT8691 Localization of Insr 4 85 0.80 9.27 30.32
84 INT5507 Regulation of Localization of Crh 2 57 0.61 8.43 30.26
85 INT28 Regulation of Gast 1 106 0.62 26.37 29.85
86 INT7397 Negative_regulation of Localization of GNRH1 5 86 0.59 15.45 29.78
87 INT5514 Negative_regulation of Localization of Crh 1 64 0.58 8.12 29.29
88 INT7035 Regulation of CGA 2 87 0.45 29.04 28.45
89 INT16879 Binding of Crh 1 72 0.48 21.65 28.43
90 INT2408 Regulation of CCK 1 37 0.61 10.01 26.66
91 INT2261 Gene_expression of Lhb 1 121 0.77 42.78 26.04
92 INT7394 Positive_regulation of Localization of GNRH1 3 67 0.69 7.22 25.29
93 INT2614 Gene_expression of CGA 1 187 0.78 105.89 24.77
94 INT2290 Protein_catabolism of POMC 1 41 0.99 4.86 23.36
95 INT250 Regulation of GHRH 1 65 0.61 17.46 23.19
96 INT825 Negative_regulation of ADRA1D 1 54 0.58 20.25 22.78
97 INT1327 Regulation of Localization of Trh 1 45 0.62 6.05 22.09
98 INT3299 Positive_regulation of AGT 1 126 0.68 79.45 21.91
99 INT6127 Regulation of Localization of AVP 1 60 0.62 15.12 20.84
100 INT1792 Positive_regulation of CGA 1 123 0.70 64.73 20.79
101 INT955 Gene_expression of GHRH 2 126 0.78 59.91 20.74
102 INT26408 Negative_regulation of da 1 36 0.18 13.46 20.32
103 INT14436 Gene_expression of Dbh 2 42 0.72 9.9 19.85
104 INT8075 Localization of Crh 2 64 0.81 25.41 19.45
105 INT11628 Regulation of Localization of Pomc 2 44 0.61 10.46 18.66
106 INT984 Positive_regulation of Localization of GHRH 3 58 0.70 12.66 16.51
107 INT6947 Negative_regulation of Gene_expression of POMC 1 37 0.59 10.32 14.14
108 INT9678 Positive_regulation of Positive_regulation of GH1 1 32 0.68 8.14 12.97
109 INT7234 Binding of GNRH1 1 43 0.47 21.59 12.36
110 INT987 Localization of TRH 2 37 0.78 10.53 11.1
111 INT10009 Positive_regulation of TRH 2 31 0.67 8.94 11.03
112 INT952 Negative_regulation of GHRH 2 57 0.56 25.3 10.34
113 INT3922 Negative_regulation of Pnmt 2 29 0.59 3.18 8.96
114 INT892 Regulation of TRH 1 23 0.60 8.46 8.54
115 INT15459 Gene_expression of TRH 1 17 0.78 4.89 8.17
116 INT34741 Positive_regulation of Gene_expression of GH1 1 58 0.67 35.06 7.8
117 INT11839 Protein_catabolism of Pomc 1 15 0.98 0.77 6.99
118 INT24622 Positive_regulation of Localization of Insr 2 15 0.69 0.32 6.85
119 INT40436 Positive_regulation of Eda 10 21 0.70 8.09 6.15
120 INT10843 Regulation of Regulation of Gh 1 14 0.22 5.56 5.93
121 INT19900 Binding of GHRH 2 22 0.37 5.75 5
122 INT7393 Negative_regulation of Positive_regulation of GNRH1 1 11 0.58 0.39 4.26
123 INT29424 Negative_regulation of Positive_regulation of Lhb 2 21 0.56 4.58 4.03
124 INT19104 Regulation of Gene_expression of Gh 1 24 0.40 8.42 3.88
125 INT949 Negative_regulation of TRH 1 12 0.43 3.06 3.4
126 INT51747 Localization of RMRP 3 5 0.65 0.22 3.06
127 INT45503 Binding of EPO 1 42 0.48 24.85 2.88
128 INT7976 Regulation of Gene_expression of CGA 1 8 0.19 1.09 2.71
129 INT25159 Regulation of Positive_regulation of TRH 1 4 0.44 0.35 2.28
130 INT114768 Regulation of Eda 5 6 0.62 1.8 2.08
131 INT51748 Negative_regulation of Localization of RMRP 2 3 0.35 0.16 2.01
132 INT29084 Regulation of Localization of Crh 2 4 0.29 1.24 1.72
133 INT954 Positive_regulation of Gene_expression of GHRH 2 18 0.50 7.6 1.63
134 INT30683 Binding of TRH 1 4 0.36 0.96 1.55
135 INT42116 Positive_regulation of ME1 1 5 0.05 1.56 1.33
136 INT77555 Positive_regulation of thd 1 8 0.05 7.82 1.06
137 INT59628 Regulation of RMRP 2 3 0.43 0 0.98
138 INT125415 Negative_regulation of Eda 1 5 0.59 0.93 0.9
139 INT114769 Regulation of Enpep 3 6 0.14 0.58 0.89
140 INT93025 Positive_regulation of RMRP 1 2 0.47 0.08 0.89
141 INT51744 Regulation of Uts2 5 8 0.56 0.23 0.86
142 INT120441 Localization of BTF3 5 2 0.06 1.25 0.81
143 INT31046 Negative_regulation of Uts2 3 6 0.42 0.44 0.76
144 INT26961 Regulation of Pyy 1 4 0.45 0.2 0.73
145 INT17698 Positive_regulation of Regulation of GH1 1 6 0.46 0.9 0.65
146 INT101016 Gene_expression of RMRP 1 4 0.63 0 0.49
147 INT120439 Positive_regulation of BTF3 1 2 0.04 0.49 0.49
148 INT33933 Negative_regulation of Hexb 2 4 0.51 0.57 0.48
149 INT72410 Regulation of Trni 2 1 0.22 1.83 0.38
150 INT144599 Gene_expression of Crhr2 1 3 0.49 2.16 0.36
151 INT51743 Gene_expression of Uts2 3 5 0.76 0.3 0.33
152 INT53854 Regulation of Negative_regulation of Uts2 2 3 0.44 0 0.29
153 INT72409 Positive_regulation of Trni 3 1 0.00 1.55 0.25
154 INT131558 Protein_catabolism of ENG 1 1 0.01 0 0.18
155 INT124232 Negative_regulation of BTF3 1 1 0.00 0.26 0.17
156 INT124233 Negative_regulation of Localization of BTF3 1 1 0.01 0.26 0.17
157 INT39203 Positive_regulation of Negative_regulation of TRH 1 2 0.49 1.08 0.14
158 INT53855 Positive_regulation of Gene_expression of Uts2 2 1 0.49 0 0.11
159 INT51742 Binding of Uts2 1 1 0.34 0 0.08
160 INT72411 Positive_regulation of Positive_regulation of Trni 1 1 0.00 0.52 0.08
161 INT19287 Negative_regulation of TIPRL 1 5 0.50 1.14 0.07
162 INT124234 Regulation of BTF3 1 1 0.00 0.17 0.07
163 INT39204 Positive_regulation of Negative_regulation of GHRH 1 1 0.49 0 0
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