J:Gut

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT104855 Prkaca Regulation of TRPV1 3 1 0.06 1.52 1.92
2 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 1 0.14 3.26 1.54
3 INT164902 Binding of IL1RL1 and IL33 4 3 0.37 1.2 0.53
4 INT164890 Binding of IL1RAP and IL33 1 3 0.09 0.2 0.36
5 INT164904 Binding of IL1A and IL33 1 2 0.39 0.19 0.35
6 INT156448 ANGPTL5 Positive_regulation of Gene_expression of COL7A1 1 1 0.00 0.46 0.33
7 INT164892 IL33 Regulation of Gene_expression of IL1RAP 1 1 0.06 0.2 0.18
8 INT164894 Binding of IL1A and IL1RAP 1 1 0.08 0.1 0.18
9 INT164908 Binding of IL1RAP and IL1RL1 1 2 0.08 0.1 0.18
10 INT252177 VEGFA Regulation of Gene_expression of CPOX 1 1 0.03 0.56 0.14
11 INT342518 HSP90B1 Positive_regulation of Gene_expression of TLR4 1 1 0.04 0.4 0.13
12 INT342520 HSP90B1 Positive_regulation of Gene_expression of TLR2 1 1 0.06 0.4 0.13
13 INT342512 Hsp90b1 Positive_regulation of Gene_expression of HSP90B1 1 1 0.24 0.62 0.03
14 INT164899 IL33 Positive_regulation of IFNG 1 1 0.25 0.05 0
15 INT156450 ANGPTL5 Positive_regulation of Positive_regulation of NFKB1 1 1 0.03 0 0
16 INT147785 POMC Positive_regulation of Gene_expression of FUT1 1 1 0.04 0 0
17 INT164907 IFNG Positive_regulation of Gene_expression of IL1RL1 1 2 0.31 0.11 0
18 INT164895 IL33 Positive_regulation of Gene_expression of CCL2 1 1 0.16 0.05 0
19 INT144261 CRH Positive_regulation of SEMA6A 1 1 0.56 0 0
20 INT164901 IL33 Positive_regulation of Gene_expression of CXCL10 1 1 0.16 0.05 0
21 INT164906 IL33 Positive_regulation of Gene_expression of IL4 1 1 0.43 0.05 0
22 INT164910 IL33 Positive_regulation of Gene_expression of CXCL1 1 1 0.12 0.05 0
23 INT164736 MIR29A Regulation of Glul 1 1 0.59 0.06 0
24 INT164896 Binding of IL1RAP and ITS 1 1 0.11 0 0
25 INT164900 STAT6 Positive_regulation of Gene_expression of IL1RL1 1 1 0.42 0.06 0
26 INT157902 hs Positive_regulation of Gene_expression of Fos 1 1 0.01 0.08 0
27 INT164891 STAT1 Positive_regulation of Gene_expression of IL1RL1 1 1 0.41 0.06 0
28 INT164905 IL1B Positive_regulation of JUN 1 1 0.13 0.07 0
29 INT156454 ANGPTL5 Positive_regulation of Pscs 1 1 0.01 0 0
30 INT164911 Binding of IL1RL1 and ITS 1 1 0.48 0 0
31 INT164897 IL4 Positive_regulation of Gene_expression of IL1RL1 1 1 0.54 0.06 0
32 INT157901 hs Positive_regulation of Fos 1 1 0.01 0.07 0
33 INT157903 Negative_regulation of hs Positive_regulation of Fos 1 1 0.01 0.07 0
34 INT156451 Negative_regulation of NFKB1 Negative_regulation of Gene_expression of ANGPTL5 1 1 0.03 0 0
35 INT163614 POMC Regulation of MME 1 2 0.08 0.39 0
36 INT164912 IL33 Positive_regulation of Gene_expression of IL8 1 1 0.45 0.05 0
37 INT156449 ANGPTL5 Positive_regulation of Gene_expression of MAPK1 1 1 0.04 0 0
38 INT164903 IL33 Positive_regulation of Gene_expression of CXCL2 1 1 0.12 0.05 0
39 INT164889 IL33 Positive_regulation of Gene_expression of IFNG 1 1 0.25 0.05 0
40 INT164898 TNF Positive_regulation of JUN 1 1 0.06 0.07 0
41 INT164909 IL33 Positive_regulation of Phosphorylation of NFKBIA 1 1 0.53 0.05 0
42 INT156452 ANGPTL5 Positive_regulation of Gene_expression of IL6 1 1 0.04 0 0
43 INT164893 IL33 Positive_regulation of Gene_expression of IL6 1 1 0.46 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 6 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1 1163 0.70 319.28 684
3 INT58061 Gene_expression of Trpv1 7 1117 0.78 451.54 637.59
4 INT9238 Gene_expression of IL6 4 1575 0.78 1135.66 424.22
5 INT64202 Positive_regulation of Trpv1 1 643 0.70 249.66 397.42
6 INT6056 Negative_regulation of Gene_expression of Fos 1 601 0.59 193.05 386.84
7 INT18357 Gene_expression of TRPV1 19 825 0.78 307.11 382.81
8 INT5680 Gene_expression of Ngf 2 530 0.78 264.29 310.56
9 INT63932 Positive_regulation of Ephb1 1 537 0.70 259.67 296.14
10 INT5379 Gene_expression of Fos 2 656 0.78 255.5 292.54
11 INT9158 Gene_expression of Tnf 1 722 0.78 522.01 277.68
12 INT9381 Positive_regulation of TRPV1 16 523 0.70 187.4 276.05
13 INT10832 Gene_expression of IL8 7 1050 0.78 698.72 270
14 INT5591 Regulation of Gene_expression of Fos 1 425 0.62 129.06 265.78
15 INT68684 Gene_expression of VEGFA 6 2371 0.78 1742.52 259.2
16 INT16868 Gene_expression of Il6 2 807 0.78 499.48 256.57
17 INT11377 Positive_regulation of Ngf 1 331 0.70 206.5 238
18 INT50670 Gene_expression of CPOX 3 763 0.76 442.13 195.02
19 INT55879 Gene_expression of CCL2 3 421 0.78 240.74 166.02
20 INT60126 Regulation of Trpv1 1 186 0.62 85.53 133.4
21 INT5380 Positive_regulation of Gene_expression of Fos 1 243 0.70 105.65 131.05
22 INT7533 Gene_expression of Tlr4 1 720 0.78 343.22 121.57
23 INT64201 Negative_regulation of Trpv1 1 203 0.59 79.18 119.75
24 INT12339 Localization of IL8 1 437 0.81 251.87 117.39
25 INT90091 Gene_expression of GOPC 1 967 0.67 366.22 103.6
26 INT89054 Positive_regulation of Gene_expression of Trpv1 2 156 0.70 90.78 102.03
27 INT7944 Positive_regulation of Fos 1 193 0.70 60.69 98.31
28 INT1760 Gene_expression of PTGER2 7 524 0.57 226.94 96.4
29 INT69764 Positive_regulation of Cnr1 1 126 0.70 67.8 91.49
30 INT74376 Gene_expression of Cnr1 1 173 0.78 73.43 89.7
31 INT71789 Positive_regulation of MAPK1 1 396 0.70 234.44 89.27
32 INT48408 Gene_expression of ICAM1 2 494 0.78 340.08 88.6
33 INT54571 Positive_regulation of NFKB1 2 263 0.70 138.99 87.32
34 INT4830 Binding of Trpv1 1 158 0.48 45.11 84.2
35 INT92434 Phosphorylation of Mapk1 3 287 0.82 91.65 83.46
36 INT8534 Localization of Pax3 1 85 0.59 28.71 82.82
37 INT16254 Positive_regulation of Gene_expression of Ngf 2 144 0.70 80.61 82.08
38 INT68682 Positive_regulation of VEGFA 9 640 0.70 454.14 81.65
39 INT12476 Negative_regulation of TRPV1 1 124 0.59 47.95 77.98
40 INT9382 Regulation of TRPV1 1 149 0.62 53.99 77.46
41 INT5056 Gene_expression of IFNG 1 216 0.78 137.52 74.57
42 INT56298 Gene_expression of IL4 1 306 0.78 182.18 72.92
43 INT49995 Positive_regulation of Gene_expression of Tnf 1 187 0.70 125.07 70.54
44 INT10837 Positive_regulation of Gene_expression of IL8 1 294 0.70 190.08 70.34
45 INT79494 Positive_regulation of Gene_expression of VEGFA 1 577 0.70 442.94 69.73
46 INT14624 Gene_expression of Pax3 2 100 0.38 33.22 69.47
47 INT7344 Gene_expression of TAC1 1 132 0.75 35.48 68.26
48 INT5374 Gene_expression of Esr1 8 412 0.77 263.89 67.34
49 INT109431 Gene_expression of Trpa1 3 123 0.78 51.84 59.98
50 INT46637 Gene_expression of CXCL10 1 172 0.78 121.94 57.74
51 INT83602 Positive_regulation of Gene_expression of TRPV1 7 114 0.70 51.19 56.35
52 INT33567 Gene_expression of CALM1 6 139 0.67 48.85 56.14
53 INT117223 Gene_expression of TLR4 1 348 0.78 206.18 54.42
54 INT84495 Positive_regulation of Positive_regulation of Ephb1 1 85 0.70 46.12 54.11
55 INT9234 Negative_regulation of Gene_expression of IL6 1 171 0.59 101.61 53.15
56 INT72182 Gene_expression of Mcpt1 1 167 0.75 123.7 52.15
57 INT40777 Positive_regulation of Akt1 1 163 0.69 59.41 49.43
58 INT109430 Positive_regulation of Trpa1 1 119 0.70 44 49.14
59 INT71786 Phosphorylation of MAPK1 3 256 0.82 110.09 46.17
60 INT80124 Negative_regulation of VEGFA 1 450 0.58 311.19 44.53
61 INT66383 Phosphorylation of Prkaca 1 143 0.80 30.85 43.38
62 INT157666 Positive_regulation of GOPC 2 335 0.60 120.19 42.75
63 INT13556 Gene_expression of CD4 1 367 0.78 230.82 41.74
64 INT5454 Localization of CRH 1 124 0.79 79.18 41.53
65 INT9094 Gene_expression of COL7A1 1 277 0.77 143.42 38.73
66 INT58062 Negative_regulation of Gene_expression of Trpv1 1 66 0.59 22.34 38.02
67 INT48222 Positive_regulation of Localization of IL8 1 123 0.59 78.04 37.2
68 INT80690 Positive_regulation of MAPK8 1 223 0.68 125.63 36.75
69 INT133028 Gene_expression of TLR2 1 209 0.73 131.92 36.17
70 INT48924 Positive_regulation of Mapk3 2 107 0.67 50.53 34.05
71 INT7133 Negative_regulation of MME 1 85 0.59 29.22 33.1
72 INT62830 Gene_expression of VCAM1 1 149 0.78 125.23 32.4
73 INT7082 Gene_expression of CRH 1 180 0.78 64.66 31.74
74 INT8027 Regulation of Gene_expression of Ngf 1 34 0.62 26.32 31.16
75 INT99688 Negative_regulation of Gene_expression of VEGFA 2 274 0.58 201.8 31.1
76 INT98522 Gene_expression of Accn3 1 68 0.78 26.95 28.6
77 INT56072 Negative_regulation of NFKB1 1 94 0.59 53.16 28.19
78 INT75418 Negative_regulation of Cnr1 1 41 0.59 14.65 27.28
79 INT95481 Regulation of Gene_expression of TRPV1 1 48 0.62 29.3 26.28
80 INT1761 Positive_regulation of PTGER2 1 135 0.49 90.17 26.26
81 INT53015 Gene_expression of TP53INP2 1 50 0.78 9.05 26.23
82 INT12124 Gene_expression of MAPK1 2 141 0.75 82.4 25.58
83 INT4877 Gene_expression of MME 5 184 0.78 122.82 24.78
84 INT74377 Regulation of Cnr1 1 38 0.59 16.93 24.77
85 INT6441 Positive_regulation of CRH 1 98 0.69 57.22 24.12
86 INT9155 Gene_expression of Glul 3 60 0.77 17.97 23.95
87 INT74423 Localization of IL10 1 91 0.80 61.6 22.95
88 INT49196 Gene_expression of SELE 1 105 0.78 107.29 22.92
89 INT91891 Gene_expression of Kit 4 268 0.78 158.89 22.67
90 INT89056 Phosphorylation of Trpv1 3 46 0.82 13.52 22.16
91 INT96511 Negative_regulation of Positive_regulation of Trpv1 1 35 0.59 10.95 19.79
92 INT1764 Negative_regulation of Gene_expression of PTGER2 2 81 0.34 34.74 19.45
93 INT62826 Negative_regulation of Gene_expression of ICAM1 1 75 0.58 46.39 17.72
94 INT116950 Negative_regulation of MAPK8 1 103 0.57 44.48 17.53
95 INT8526 Negative_regulation of Positive_regulation of Fos 1 26 0.59 5.99 17.52
96 INT35487 Localization of PTGER2 1 103 0.46 51.24 17.45
97 INT68681 Transcription of VEGFA 1 132 0.71 80.47 17.03
98 INT120966 Positive_regulation of Pik3cb 1 34 0.68 15.15 16.59
99 INT109929 Phosphorylation of MAPK8 1 102 0.81 39.98 16.54
100 INT170855 Negative_regulation of GOPC 2 188 0.38 70.92 15.41
101 INT24798 Negative_regulation of Glul 1 52 0.55 27.25 15.17
102 INT75540 Positive_regulation of TH1L 1 62 0.67 43.45 15.02
103 INT10709 Negative_regulation of CD4 1 106 0.59 95.6 14.89
104 INT67641 Negative_regulation of Gene_expression of Tlr4 1 90 0.58 46 14.6
105 INT16321 Gene_expression of Cd3e 2 111 0.72 49.9 14.21
106 INT79149 Gene_expression of CSE 2 26 0.58 11.76 14.16
107 INT103828 Negative_regulation of Gene_expression of TRPV1 1 23 0.59 13.63 13.81
108 INT52905 Gene_expression of Cd4 1 84 0.78 45.68 12.75
109 INT83201 Gene_expression of NOS3 1 93 0.78 47.16 12.48
110 INT121223 Positive_regulation of Gene_expression of Pax3 1 17 0.16 4.52 12.06
111 INT102272 Regulation of TH1L 2 41 0.44 30.89 11.63
112 INT148639 Gene_expression of Uchl1 1 30 0.59 16.76 11.54
113 INT1762 Negative_regulation of PTGER2 1 64 0.43 28.21 11.27
114 INT49266 Positive_regulation of Arigg4 1 37 0.47 53.79 11.2
115 INT96271 Positive_regulation of Gene_expression of Mcpt1 1 30 0.53 21.34 11.06
116 INT62895 Gene_expression of NOSTRIN 1 51 0.75 28.8 10.68
117 INT244490 Gene_expression of HSP90B1 43 4 0.33 41.16 10.37
118 INT89053 Positive_regulation of Phosphorylation of Trpv1 1 16 0.70 8.89 9.39
119 INT101105 Positive_regulation of FUT1 2 62 0.30 55.96 9.28
120 INT94196 Negative_regulation of Phosphorylation of MAPK1 1 60 0.59 31.64 9.16
121 INT17024 Gene_expression of COL1A2 1 69 0.77 36.38 8.29
122 INT130502 Negative_regulation of Trpa1 1 17 0.59 5.75 8.06
123 INT24799 Regulation of Glul 1 22 0.45 8.3 8
124 INT88868 Binding of MCS 1 45 0.40 37.43 7.98
125 INT82762 Positive_regulation of Positive_regulation of Mapk3 1 23 0.67 7.72 7.91
126 INT36135 Negative_regulation of CSE 1 19 0.50 1.77 7.81
127 INT96994 Phosphorylation of EGFR 1 99 0.82 52.75 7.33
128 INT14599 Localization of Tpsab1 3 36 0.79 14.58 7.18
129 INT58083 Positive_regulation of DYT10 1 10 0.67 3.66 7.12
130 INT127691 Gene_expression of CXCL1 1 23 0.66 18.11 7.04
131 INT175482 Positive_regulation of Gene_expression of CALM1 1 12 0.44 3.47 6.54
132 INT9951 Gene_expression of ANGPTL5 3 45 0.53 37.2 6.44
133 INT9118 Gene_expression of Ceacam1 1 37 0.75 17.19 6.12
134 INT93007 Regulation of Gene_expression of CALM1 2 7 0.41 3.47 6.08
135 INT86111 Positive_regulation of Positive_regulation of VEGFA 1 38 0.69 33.81 5.78
136 INT43997 Positive_regulation of Gene_expression of Esr1 3 57 0.51 36.66 5.51
137 INT62510 Positive_regulation of MCS 1 32 0.60 11.79 5.45
138 INT11062 Positive_regulation of MME 1 24 0.63 14.37 5.26
139 INT62832 Negative_regulation of Gene_expression of SELE 1 16 0.49 10.6 5.12
140 INT61452 Gene_expression of IL1RAP 5 15 0.58 7.21 5.09
141 INT83680 Gene_expression of FUT1 5 40 0.26 25.45 4.98
142 INT99690 Negative_regulation of Positive_regulation of VEGFA 3 30 0.58 14.56 4.79
143 INT70654 Gene_expression of Actg2 1 27 0.67 18.62 4.79
144 INT83837 Gene_expression of CEACAM6 9 7 0.76 13.8 4.59
145 INT62813 Negative_regulation of ZNF398 2 12 0.09 6.2 4.49
146 INT62821 Negative_regulation of Gene_expression of VCAM1 1 21 0.54 12.24 4.41
147 INT142752 Positive_regulation of Myd88 1 26 0.66 12.07 4.4
148 INT88278 Binding of Kit 1 33 0.37 24.45 4.13
149 INT145693 Gene_expression of Slc10a2 4 5 0.78 2.54 4.13
150 INT147028 Negative_regulation of Accn2 1 6 0.14 2.06 3.92
151 INT83887 Gene_expression of HMOX2 1 10 0.77 7.99 3.85
152 INT7559 Transcription of CRH 2 37 0.69 4.84 3.61
153 INT50648 Negative_regulation of Gene_expression of Glul 1 9 0.58 2.7 3.53
154 INT15299 Gene_expression of IL1RL1 7 37 0.69 10.09 3.43
155 INT14281 Gene_expression of Hspa5 4 44 0.63 34.19 3.31
156 INT109914 Positive_regulation of MAPK9 1 16 0.56 7.64 3.27
157 INT99687 Negative_regulation of Transcription of VEGFA 1 17 0.43 10.3 3.25
158 INT164920 Gene_expression of IL33 6 22 0.76 13.63 3.16
159 INT138350 Regulation of Phosphorylation of Trpv1 2 6 0.58 1.87 3.16
160 INT25122 Binding of PTGER2 1 31 0.31 13.83 3.12
161 INT244512 Positive_regulation of Gene_expression of HSP90B1 14 2 0.30 12.08 3.12
162 INT157904 Positive_regulation of Gene_expression of CSE 1 2 0.39 1.35 3.01
163 INT195978 Gene_expression of Hsp90b1 2 26 0.65 11.28 2.88
164 INT16447 Binding of IL1A 1 10 0.45 4.01 2.78
165 INT73837 Positive_regulation of Gene_expression of TAC1 1 6 0.67 3.49 2.68
166 INT169987 Transcription of GOPC 1 45 0.60 21.88 2.61
167 INT122003 Phosphorylation of NFKBIA 1 9 0.59 5.44 2.51
168 INT4879 Positive_regulation of Gene_expression of MME 1 17 0.69 12.48 2.46
169 INT111016 Gene_expression of F2rl1 1 11 0.73 3.58 2.37
170 INT110304 Negative_regulation of Gene_expression of NOSTRIN 1 6 0.55 2.22 2.27
171 INT128745 Positive_regulation of Positive_regulation of Pik3cb 1 4 0.56 0.95 2.24
172 INT149031 Gene_expression of Tjp1 2 43 0.75 19.1 2.06
173 INT195968 Positive_regulation of Gene_expression of Hsp90b1 3 10 0.49 5.21 2.02
174 INT152771 Gene_expression of TJP1 2 19 0.75 14.95 1.98
175 INT101148 Gene_expression of UCHL1 1 20 0.70 9.61 1.8
176 INT82760 Negative_regulation of Positive_regulation of Mapk3 1 7 0.57 3.18 1.78
177 INT118292 Negative_regulation of Phosphorylation of EGFR 1 27 0.59 13.62 1.54
178 INT156485 Positive_regulation of Gene_expression of CEACAM6 3 3 0.49 6.5 1.54
179 INT299114 Localization of FANCE 1 5 0.53 3.37 1.49
180 INT123926 Gene_expression of Angpt1 2 28 0.54 21.74 1.47
181 INT308527 Regulation of Gene_expression of HSP90B1 5 2 0.26 5.31 1.46
182 INT112109 Gene_expression of FIGF 2 13 0.31 8.31 1.44
183 INT147788 Regulation of FUT1 1 11 0.12 7.72 1.44
184 INT121820 Binding of STAT1 1 9 0.46 2.54 1.4
185 INT164915 Gene_expression of CXCL2 1 7 0.55 5.25 1.4
186 INT91863 Negative_regulation of Gene_expression of NOS3 1 13 0.51 9.43 1.34
187 INT118910 Gene_expression of S100a10 1 3 0.49 1.6 1.28
188 INT6630 Binding of IL1RAP 1 4 0.17 1.07 1.08
189 INT117622 Positive_regulation of HSP90B1 4 3 0.43 4.84 1.02
190 INT232636 Positive_regulation of Binding of Kit 1 4 0.39 1.98 0.98
191 INT184418 Negative_regulation of Positive_regulation of GOPC 2 15 0.26 5.47 0.87
192 INT178498 Negative_regulation of Fgf2 1 11 0.42 4.21 0.84
193 INT337008 Binding of HSP90B1 9 2 0.20 4.91 0.81
194 INT145692 Regulation of Gene_expression of Slc10a2 1 2 0.61 0.71 0.8
195 INT127591 Binding of Ceacam1 1 7 0.35 2.18 0.79
196 INT98567 Negative_regulation of Gene_expression of Cd4 1 8 0.40 6.1 0.75
197 INT256673 Positive_regulation of Hsp90b1 1 12 0.49 8.49 0.68
198 INT342507 Regulation of HSP90B1 2 1 0.26 2.29 0.67
199 INT164916 Binding of IL1RL1 1 9 0.33 1.84 0.66
200 INT322286 Localization of CEACAM6 3 2 0.41 2.3 0.57
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