J:Handb Exp Pharmacol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT139723 PROC Positive_regulation of MAPK8 1 2 0.01 2.98 2.33
2 INT139722 PROC Positive_regulation of CDCP1 1 1 0.00 1.61 1.29
3 INT139724 PROC Positive_regulation of MAPK14 1 1 0.00 1.57 1.25

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2543 Positive_regulation of Calca 1 787 0.70 331.13 592.08
2 INT50058 Negative_regulation of Cpox 1 907 0.58 426.28 428.29
3 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
4 INT720 Positive_regulation of POMC 2 807 0.70 237.37 353.83
5 INT9381 Positive_regulation of TRPV1 4 523 0.70 187.4 276.05
6 INT1562 Localization of Crh 2 499 0.81 126.74 236.68
7 INT626 Localization of CALCA 1 289 0.81 125.39 221.15
8 INT24326 Gene_expression of Ngf 1 346 0.78 218.67 184.71
9 INT6323 Positive_regulation of Gabrg1 2 213 0.70 45.08 124.34
10 INT8413 Gene_expression of Ptgs1 1 248 0.78 110.17 108.58
11 INT74376 Gene_expression of Cnr1 2 173 0.78 73.43 89.7
12 INT12476 Negative_regulation of TRPV1 1 124 0.59 47.95 77.98
13 INT9382 Regulation of TRPV1 2 149 0.62 53.99 77.46
14 INT65733 Positive_regulation of Cnr1 1 125 0.70 40.27 67.33
15 INT1599 Positive_regulation of ADCY1 1 146 0.67 30.05 64.9
16 INT6894 Gene_expression of CNR1 1 168 0.78 74.07 62.84
17 INT69876 Negative_regulation of Nfkb1 1 147 0.58 89.81 55.5
18 INT5509 Positive_regulation of Localization of Crh 2 91 0.70 30.65 53.92
19 INT8700 Positive_regulation of Positive_regulation of Calca 1 56 0.67 21.69 53.66
20 INT5338 Regulation of Npy 1 92 0.62 25.54 51.24
21 INT76620 Gene_expression of Cnr2 1 93 0.78 34.7 50.14
22 INT64436 Gene_expression of P2rx1 1 93 0.78 32.69 36.12
23 INT109820 Gene_expression of Trpv4 1 121 0.78 39.69 33.11
24 INT96913 Positive_regulation of Mapk8 2 179 0.69 130.44 32.2
25 INT22239 Negative_regulation of TAC1 1 52 0.57 12.96 31.41
26 INT46833 Positive_regulation of SGSM3 3 56 0.67 24.49 30.31
27 INT5507 Regulation of Localization of Crh 1 57 0.61 8.43 30.26
28 INT6660 Positive_regulation of Jun 1 148 0.69 67.58 29.73
29 INT7832 Localization of Cck 2 39 0.81 6.81 26.54
30 INT101592 Gene_expression of TRPM8 1 82 0.78 70.61 22.89
31 INT3364 Binding of SGCG 1 87 0.47 31.93 17.24
32 INT109316 Negative_regulation of Mapk8 2 72 0.59 50.59 17.24
33 INT48238 Regulation of Gene_expression of Ngf 1 25 0.62 11.48 16.42
34 INT75521 Positive_regulation of Positive_regulation of SGSM3 2 13 0.67 7.99 13.54
35 INT83894 Positive_regulation of TRPM8 1 37 0.70 18.28 11.7
36 INT36715 Gene_expression of Trpc4 1 50 0.68 4.18 11.13
37 INT14132 Negative_regulation of HTR1A 1 25 0.57 4.93 10.91
38 INT86729 Positive_regulation of CDCP1 1 37 0.07 18.74 10.76
39 INT127978 Gene_expression of Trpc5 1 58 0.67 3.11 10.21
40 INT51837 Negative_regulation of TACR1 2 17 0.43 6.5 9.12
41 INT75250 Negative_regulation of Positive_regulation of SGSM3 1 5 0.57 2.47 5.24
42 INT101593 Positive_regulation of Gene_expression of TRPM8 1 16 0.70 13.79 4.23
43 INT108823 Binding of COX5A 2 8 0.47 4.06 4.14
44 INT6661 Positive_regulation of Positive_regulation of Jun 1 31 0.50 7.12 3.89
45 INT93110 Regulation of CDCP1 1 16 0.03 7.98 3.83
46 INT109851 Negative_regulation of P2RX3 1 7 0.57 3.55 3.61
47 INT101068 Negative_regulation of CDCP1 1 27 0.03 17.67 3.45
48 INT57811 Regulation of Localization of Cck 2 3 0.60 2.17 2.62
49 INT114773 Negative_regulation of GABBR1 1 4 0.43 0.55 2.33
50 INT81155 Localization of CDCP1 1 5 0.08 4.49 1.4
51 INT139725 Binding of CDCP1 1 3 0.01 2.1 1.4
52 INT139727 Positive_regulation of Localization of CDCP1 1 1 0.01 1.64 1.3
53 INT138815 Regulation of Binding of COX5A 2 3 0.44 1.06 1.29
54 INT162064 Gene_expression of PKD2L1 1 12 0.63 2.71 1.1
55 INT2142 Regulation of Ptgir 1 7 0.42 3.35 1.02
56 INT139726 Negative_regulation of MS 1 1 0.02 1.16 0.83
57 INT165104 Negative_regulation of Negative_regulation of Mapk8 1 5 0.43 4.21 0.77
58 INT165105 Localization of Mapk8 1 7 0.69 4.45 0.76
59 INT137850 Gene_expression of PKD2 1 9 0.65 6.68 0.63
60 INT154998 Negative_regulation of NOP56P1 1 1 0.10 0.39 0.58
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