J:Hepatology

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 2 0.21 0.93 0.94
2 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 1 0.40 0.49 0.48
3 INT118396 Nfe2l2 Positive_regulation of Gene_expression of Cars 1 1 0.05 0.26 0.47
4 INT102552 HGF Positive_regulation of MAPK3 1 1 0.38 0.47 0.47
5 INT102556 HGF Positive_regulation of Phosphorylation of ELK1 1 1 0.10 0.46 0.47
6 INT102555 HGF Positive_regulation of MAPK1 1 1 0.38 0.47 0.47
7 INT17726 Positive_regulation of Binding of AKR1A1 and Aldh2 1 1 0.11 0.35 0.41
8 INT17725 Binding of AKR1A1 and Aldh2 1 1 0.08 0.35 0.4
9 INT110758 Tnfaip8 Positive_regulation of Positive_regulation of Nos2 1 1 0.14 0.88 0.34
10 INT110760 Tnfaip8 Positive_regulation of Positive_regulation of Nfkb1 1 1 0.14 0.87 0.34
11 INT110761 Tnfaip8 Positive_regulation of Nos2 1 1 0.13 0.88 0.34
12 INT110759 Tnfaip8 Positive_regulation of Nfkb1 1 1 0.13 0.87 0.34
13 INT129594 St13 Positive_regulation of Positive_regulation of Tnf 1 1 0.26 0.85 0.21
14 INT69949 Car2 Positive_regulation of MTAP 1 1 0.02 0.41 0.18
15 INT129592 St13 Positive_regulation of Protein_catabolism of Stat3 1 1 0.26 0.84 0.16
16 INT129593 St13 Positive_regulation of Positive_regulation of Stat3 1 1 0.28 0.84 0.16
17 INT89723 RYBP Positive_regulation of Fos 1 1 0.01 0.31 0.08
18 INT89725 RYBP Positive_regulation of Transcription of Fos 1 1 0.01 0.31 0.08
19 INT89726 RYBP Positive_regulation of Jun 1 1 0.01 0.31 0.08
20 INT89724 RYBP Positive_regulation of Gclc 1 1 0.01 0.21 0.07
21 INT110751 IL12A Negative_regulation of KRR1 1 1 0.64 0.57 0.05
22 INT142932 Binding of Arid1a and Samsn1 1 1 0.01 1.55 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 5 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
3 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
4 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
5 INT439 Localization of Gnrh1 1 976 0.81 100.96 363.25
6 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
7 INT49750 Negative_regulation of CPOX 3 735 0.58 360.06 274.19
8 INT6852 Localization of TNF 3 883 0.81 705.95 270.84
9 INT16868 Gene_expression of Il6 2 807 0.78 499.48 256.57
10 INT1562 Localization of Crh 3 499 0.81 126.74 236.68
11 INT48955 Gene_expression of Nos2 2 753 0.78 403.87 208.08
12 INT2391 Negative_regulation of PTGS1 2 501 0.59 207.62 205.6
13 INT6488 Gene_expression of Tnf 2 484 0.78 339.61 191.58
14 INT1652 Regulation of Pomc 1 387 0.62 61.01 186.51
15 INT10194 Positive_regulation of IL6 2 702 0.70 600.62 183.38
16 INT19472 Gene_expression of Il1 1 554 0.76 419.75 175.35
17 INT867 Gene_expression of IFNA1 2 930 0.78 594.85 168.03
18 INT66280 Gene_expression of Nos2 2 534 0.78 330.78 157.07
19 INT60694 Gene_expression of Il10 2 567 0.78 369.48 143.69
20 INT9660 Regulation of TNF 3 363 0.62 312.94 139.99
21 INT48895 Gene_expression of Il10 1 333 0.78 221.2 138.52
22 INT48953 Positive_regulation of Nos2 2 486 0.70 239.85 131.87
23 INT8243 Positive_regulation of Il6 2 451 0.70 358.24 119.28
24 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
25 INT50674 Gene_expression of PTGS2 1 459 0.78 253.33 118.51
26 INT27096 Positive_regulation of Nfkb1 8 325 0.70 195.11 109.06
27 INT3038 Gene_expression of INS 1 1583 0.78 1174.16 107.01
28 INT69440 Gene_expression of ROS1 2 752 0.78 477.64 103.83
29 INT1898 Regulation of Crh 1 220 0.62 61.33 102.64
30 INT2159 Regulation of Localization of Gnrh1 1 200 0.62 13.28 99.07
31 INT7944 Positive_regulation of Fos 2 193 0.70 60.69 98.31
32 INT54571 Positive_regulation of NFKB1 1 263 0.70 138.99 87.32
33 INT22967 Positive_regulation of RYBP 3 94 0.56 37.04 85.92
34 INT5617 Localization of Nppa 2 266 0.81 83.51 83.89
35 INT56291 Gene_expression of Ros1 3 503 0.63 274.12 81.5
36 INT48244 Gene_expression of Il4 1 172 0.76 132.38 73.42
37 INT7534 Gene_expression of Ifng 1 193 0.78 111.02 68.6
38 INT6489 Positive_regulation of Gene_expression of Tnf 2 140 0.70 92.31 67.85
39 INT19511 Localization of Il6 1 212 0.81 118.17 67.67
40 INT102546 Gene_expression of Ccl2 1 197 0.78 192.8 67.41
41 INT6486 Positive_regulation of Tnf 1 168 0.70 123.47 66.05
42 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
43 INT5058 Positive_regulation of IFNA1 2 356 0.70 245.75 60.52
44 INT103924 Positive_regulation of Akt1 1 359 0.69 158.94 60.34
45 INT50672 Positive_regulation of CPOX 1 205 0.44 125.93 60.06
46 INT18883 Negative_regulation of RYBP 2 53 0.56 21.14 57.52
47 INT48891 Positive_regulation of Il10 1 143 0.70 101.42 56.72
48 INT314 Positive_regulation of Ren 1 212 0.70 66.68 55.56
49 INT69876 Negative_regulation of Nfkb1 5 147 0.58 89.81 55.5
50 INT63975 Positive_regulation of Il10 1 175 0.68 134.13 54.69
51 INT5509 Positive_regulation of Localization of Crh 1 91 0.70 30.65 53.92
52 INT48952 Negative_regulation of Nos2 2 204 0.59 101.73 53.15
53 INT62543 Gene_expression of Icam1 1 231 0.78 187.58 52.71
54 INT5623 Positive_regulation of Nppa 1 174 0.70 69.96 52.33
55 INT72182 Gene_expression of Mcpt1 3 167 0.75 123.7 52.15
56 INT2604 Positive_regulation of Got1 6 223 0.70 154.78 49.51
57 INT2463 Localization of CCK 1 101 0.81 37.54 47.59
58 INT55670 Negative_regulation of Gene_expression of Tnf 1 83 0.59 57.16 46.33
59 INT4656 Localization of RYBP 3 49 0.77 5.28 46.21
60 INT71786 Phosphorylation of MAPK1 1 256 0.82 110.09 46.17
61 INT16364 Gene_expression of HLA-DRA 10 234 0.78 118.81 45.01
62 INT100939 Gene_expression of Il13 1 176 0.73 125.1 43.38
63 INT60695 Positive_regulation of Gene_expression of Il10 1 154 0.70 120.28 43.07
64 INT52531 Gene_expression of Nfkb1 2 153 0.75 82.84 42.9
65 INT85943 Negative_regulation of Nos2 1 161 0.59 108.56 42.65
66 INT1931 Positive_regulation of Gene_expression of POMC 1 116 0.70 37.26 38.67
67 INT55135 Positive_regulation of Gene_expression of PTGS2 1 137 0.70 80.32 38.46
68 INT3971 Positive_regulation of Alb 2 175 0.70 98.46 36.45
69 INT53577 Negative_regulation of Localization of TNF 2 110 0.59 59.28 35.23
70 INT79060 Gene_expression of NOS2 3 116 0.78 69.25 34.84
71 INT234 Binding of Alb 3 151 0.48 52.34 32.97
72 INT6302 Binding of IFNA1 1 196 0.48 133.85 32.73
73 INT20307 Positive_regulation of Cyp2e1 9 70 0.70 23.59 32.49
74 INT96913 Positive_regulation of Mapk8 2 179 0.69 130.44 32.2
75 INT2884 Positive_regulation of CCK 2 66 0.69 25.25 30.6
76 INT6660 Positive_regulation of Jun 3 148 0.69 67.58 29.73
77 INT660 Negative_regulation of REN 1 194 0.59 82.06 29.46
78 INT5514 Negative_regulation of Localization of Crh 1 64 0.58 8.12 29.29
79 INT87212 Negative_regulation of Positive_regulation of Nfkb1 4 74 0.57 38.21 28.31
80 INT8205 Negative_regulation of Nppa 1 77 0.59 26.43 25.72
81 INT5622 Gene_expression of Nppa 1 101 0.78 49.46 25.31
82 INT93626 Gene_expression of Fasl 2 118 0.75 115.24 25.11
83 INT50039 Positive_regulation of Il4 1 48 0.55 34.8 23.34
84 INT18884 Regulation of RYBP 2 25 0.38 11.43 23.2
85 INT71875 Localization of Nfkb1 2 92 0.78 48.13 22.94
86 INT17962 Regulation of Car2 1 124 0.41 33.98 22.71
87 INT47859 Negative_regulation of Cyp2e1 2 41 0.59 16.92 21.72
88 INT14700 Regulation of IFNA1 1 111 0.45 66.16 21.52
89 INT69877 Positive_regulation of Positive_regulation of Nfkb1 1 53 0.68 31.44 20.7
90 INT53575 Regulation of Gene_expression of Tnf 1 46 0.62 34.35 20.63
91 INT86751 Negative_regulation of Il10 1 62 0.59 40.1 20.51
92 INT14701 Negative_regulation of IFNA1 3 118 0.54 84.19 20.08
93 INT102545 Gene_expression of Ccr2 1 42 0.78 61.43 19.81
94 INT3952 Negative_regulation of ALB 1 116 0.59 72.18 18.35
95 INT14111 Positive_regulation of Cyp2c22 1 41 0.67 7.24 17.88
96 INT109316 Negative_regulation of Mapk8 1 72 0.59 50.59 17.24
97 INT61513 Positive_regulation of Gpx1 1 71 0.64 37.91 17.07
98 INT48690 Localization of Grip2 2 33 0.61 6.13 16.81
99 INT48892 Transcription of Il10 1 31 0.71 27.26 16.77
100 INT6150 Positive_regulation of Negative_regulation of Calca 1 20 0.68 4.06 16.26
101 INT10323 Gene_expression of Fam166a 1 48 0.00 11.76 15.68
102 INT75531 Regulation of MAPK1 1 70 0.61 34.39 15.42
103 INT81627 Gene_expression of Fas 2 120 0.78 115.51 15.36
104 INT1154 Negative_regulation of CCK 1 24 0.59 9.3 15.32
105 INT129584 Positive_regulation of Stat3 6 97 0.68 87.07 14.86
106 INT11340 Positive_regulation of SLC17A5 3 120 0.67 113.52 14.5
107 INT11762 Regulation of Dbi 1 40 0.62 7.83 14.48
108 INT100938 Positive_regulation of Il13 1 47 0.69 42.11 14.36
109 INT19408 Negative_regulation of Cyp2c22 2 37 0.59 6.23 14.22
110 INT16919 Gene_expression of IL36RN 2 48 0.48 32.78 13.83
111 INT69435 Negative_regulation of ROS1 1 74 0.51 50.38 13.71
112 INT17565 Regulation of Gpt 3 85 0.60 43.64 13.68
113 INT71879 Negative_regulation of Localization of Nfkb1 2 30 0.57 21.8 13.48
114 INT80222 Negative_regulation of Bcl2 1 82 0.58 69.16 13.18
115 INT81629 Positive_regulation of Fas 1 58 0.70 59.63 12.94
116 INT10585 Localization of NAGLU 2 53 0.80 23.32 12.75
117 INT12135 Gene_expression of PLEK 1 62 0.75 34.13 12.47
118 INT3969 Positive_regulation of Sds 1 27 0.69 7.52 12.31
119 INT69436 Negative_regulation of Gene_expression of ROS1 1 81 0.38 46.58 12.22
120 INT8629 Positive_regulation of COL7A1 1 72 0.69 40.66 12.09
121 INT61946 Positive_regulation of HGF 1 57 0.69 38.93 11.99
122 INT11121 Positive_regulation of NPPA 1 64 0.70 34.09 11.96
123 INT96915 Phosphorylation of Mapk8 1 73 0.81 40.69 11.44
124 INT95369 Positive_regulation of Gene_expression of NOS2 1 36 0.55 25.09 11.37
125 INT73959 Positive_regulation of NOSTRIN 1 49 0.61 31.1 11.27
126 INT71189 Gene_expression of Cyp1a2 2 24 0.78 11.39 11.12
127 INT62580 Gene_expression of Cyp2e1 1 31 0.78 15.4 11.08
128 INT96271 Positive_regulation of Gene_expression of Mcpt1 1 30 0.53 21.34 11.06
129 INT62895 Gene_expression of NOSTRIN 1 51 0.75 28.8 10.68
130 INT11936 Positive_regulation of Positive_regulation of Il6 1 34 0.50 26.85 10.59
131 INT23177 Negative_regulation of Gene_expression of HLA-DRA 3 50 0.44 16.99 10.55
132 INT9385 Localization of LDHA 1 74 0.81 31.67 10.5
133 INT78695 Regulation of Casp3 1 24 0.44 9.43 10.48
134 INT39699 Negative_regulation of Positive_regulation of RYBP 2 11 0.41 3.73 10.42
135 INT87451 Positive_regulation of Mapk3 1 34 0.67 12.82 10.38
136 INT35612 Gene_expression of REG3A 6 37 0.78 33.33 10.13
137 INT47860 Negative_regulation of Cyp1a2 1 20 0.57 6.06 10
138 INT7995 Positive_regulation of Lta 1 28 0.66 14.98 9.8
139 INT8527 Positive_regulation of Positive_regulation of Fos 1 20 0.70 6.87 9.62
140 INT11679 Negative_regulation of F13A1 1 55 0.54 33.69 9.43
141 INT129585 Gene_expression of St13 2 17 0.59 4.46 9.3
142 INT6510 Gene_expression of AFP 2 130 0.78 119.2 9.19
143 INT285 Positive_regulation of Salpa1 2 73 0.68 61.47 9.19
144 INT94196 Negative_regulation of Phosphorylation of MAPK1 1 60 0.59 31.64 9.16
145 INT69264 Gene_expression of KIT 1 207 0.78 179.41 8.95
146 INT2885 Positive_regulation of Localization of CCK 1 19 0.70 9.92 8.94
147 INT61264 Regulation of Jun 1 36 0.61 18.42 8.71
148 INT64815 Binding of Jun 1 49 0.48 21.47 8.59
149 INT97331 Positive_regulation of Timp1 2 20 0.45 13.32 8.57
150 INT96912 Positive_regulation of Phosphorylation of Mapk8 1 29 0.69 18.33 8.14
151 INT82450 Negative_regulation of Hmox1 1 33 0.55 19.07 8.12
152 INT80220 Positive_regulation of Bcl2 2 71 0.58 57.73 7.86
153 INT85751 Positive_regulation of Positive_regulation of Nos2 1 40 0.60 23.53 7.72
154 INT8669 Positive_regulation of Afp 5 66 0.70 58.21 7.67
155 INT64816 Transcription of Jun 1 31 0.69 16.01 7.64
156 INT103925 Negative_regulation of Positive_regulation of Akt1 1 32 0.58 15.19 7.39
157 INT102548 Negative_regulation of Ccr2 1 14 0.59 19.84 7.22
158 INT6210 Binding of Nppa 1 39 0.47 14.35 7.21
159 INT717 Regulation of F2 1 29 0.61 17.46 6.99
160 INT5864 Localization of IL36RN 1 19 0.44 14.5 6.87
161 INT112459 Localization of Gba 4 12 0.80 1.45 6.4
162 INT11177 Localization of Ldha 1 17 0.81 5.74 6.13
163 INT17779 Negative_regulation of Got1 1 12 0.40 3.5 6.08
164 INT67397 Transcription of Il4 1 15 0.54 11.36 6.06
165 INT88873 Negative_regulation of Gene_expression of Nfkb1 1 24 0.56 9.93 5.97
166 INT118388 Localization of Nfe2l2 2 40 0.81 9.59 5.89
167 INT95616 Gene_expression of Thpo 3 48 0.78 21.51 5.88
168 INT48004 Positive_regulation of Negative_regulation of PTGS1 1 12 0.49 4.07 5.87
169 INT18677 Gene_expression of F3 1 50 0.65 30.86 5.86
170 INT42378 Positive_regulation of Socs3 1 21 0.67 15.81 5.71
171 INT38671 Positive_regulation of KRT20 1 62 0.53 40.17 5.6
172 INT8866 Positive_regulation of TAT 2 30 0.67 18.06 5.57
173 INT22839 Gene_expression of F2 1 31 0.74 15.53 5.56
174 INT62579 Negative_regulation of Gene_expression of Cyp2e1 1 8 0.59 2.95 5.48
175 INT102547 Gene_expression of Cd68 2 25 0.75 14.47 5.22
176 INT27415 Negative_regulation of Positive_regulation of Got1 3 15 0.51 10.99 5.14
177 INT38251 Negative_regulation of Gclc 1 7 0.57 1.37 5.06
178 INT1317 Negative_regulation of Sds 1 23 0.48 6.97 5.03
179 INT111594 Positive_regulation of Gene_expression of NOSTRIN 1 20 0.32 8.69 5
180 INT106131 Negative_regulation of Abcc3 1 8 0.58 3.17 4.86
181 INT108919 Positive_regulation of Mapk9 1 9 0.34 3.55 4.74
182 INT69966 Positive_regulation of Negative_regulation of CPOX 1 11 0.45 6.18 4.64
183 INT80696 Positive_regulation of Thpo 2 16 0.70 13.75 4.49
184 INT47766 Transcription of Fos 1 25 0.69 8.78 4.42
185 INT5619 Positive_regulation of Gene_expression of Nppa 1 21 0.70 11.95 4.41
186 INT85126 Negative_regulation of MAP2K6 1 19 0.39 12.12 4.39
187 INT4134 Negative_regulation of Glce 4 11 0.58 2.97 4.28
188 INT745 Gene_expression of Afp 1 65 0.78 52.89 4.24
189 INT127039 Negative_regulation of Ppig 1 13 0.21 5.29 3.87
190 INT95423 Negative_regulation of Bcl2l1 3 26 0.41 21.66 3.81
191 INT64817 Positive_regulation of Binding of Jun 1 16 0.69 6.78 3.81
192 INT79096 Binding of Cyp2e1 2 12 0.48 4.41 3.8
193 INT10325 Positive_regulation of Gene_expression of Fam166a 2 11 0.08 6.07 3.74
194 INT38065 Localization of Sfat 1 3 0.03 1.26 3.71
195 INT17716 Gene_expression of Aldh2 2 14 0.77 4.38 3.61
196 INT89966 Negative_regulation of Fas 1 26 0.58 24.83 3.5
197 INT2723 Gene_expression of Salpa1 1 16 0.64 11.78 3.5
198 INT38303 Binding of Gpt 1 21 0.47 15.84 3.43
199 INT8539 Negative_regulation of Serpina1a 1 21 0.58 12.65 3.39
200 INT118393 Positive_regulation of Localization of Nfe2l2 2 9 0.70 2.82 3.3
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