J:Hepatology (Baltimore, Md.)

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT249347 Binding of FOS and JUN 4 1 0.19 6.15 0.89
2 INT294451 KLK4 Negative_regulation of IL8 1 2 0.01 0 0.1
3 INT294449 KLK4 Negative_regulation of MMP9 1 2 0.01 0 0.1
4 INT294445 KLK4 Negative_regulation of COL1A1 1 2 0.01 0 0.1
5 INT294440 KLK4 Negative_regulation of LIF 1 2 0.00 0 0.1
6 INT294456 KLK4 Negative_regulation of SERPINB2 1 2 0.01 0 0.1
7 INT294446 KLK4 Negative_regulation of HAS2 1 2 0.01 0 0.1
8 INT294454 KLK4 Negative_regulation of PTGS2 1 2 0.01 0 0.1
9 INT294441 KLK4 Negative_regulation of CXCR4 1 2 0.01 0 0.1
10 INT294452 KLK4 Negative_regulation of CCL4 1 2 0.00 0 0.1
11 INT294438 KLK4 Negative_regulation of IL1A 1 2 0.00 0 0.1
12 INT156749 Gpt Positive_regulation of Gene_expression of Gpt2 1 1 0.50 0.22 0.1
13 INT294437 KLK4 Negative_regulation of CXCL1 1 2 0.00 0 0.1
14 INT294453 KLK4 Negative_regulation of CCL2 1 2 0.00 0 0.1
15 INT294442 KLK4 Negative_regulation of IL6 1 2 0.00 0 0.1
16 INT294455 KLK4 Negative_regulation of HIF1A 1 2 0.01 0 0.1
17 INT294450 KLK4 Negative_regulation of SERPINE1 1 2 0.01 0 0.1
18 INT156751 Gpt2 Positive_regulation of Gpt 1 1 0.12 0.21 0.1
19 INT294457 KLK4 Negative_regulation of MMP2 1 2 0.01 0 0.1
20 INT294448 KLK4 Negative_regulation of CTGF 1 2 0.01 0 0.1
21 INT294439 KLK4 Negative_regulation of THBS1 1 2 0.01 0 0.1
22 INT294443 KLK4 Negative_regulation of CXCL5 1 2 0.00 0 0.1
23 INT156750 Gpt Positive_regulation of Gpt 1 1 0.27 0.22 0.1
24 INT294444 KLK4 Negative_regulation of CCL3 1 2 0.00 0 0.1
25 INT153696 Binding of GSTM1 and Gstt1 1 1 0.06 0.71 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
2 INT34869 Negative_regulation of PTGS2 2 778 0.59 366.76 319.85
3 INT10832 Gene_expression of IL8 8 1050 0.78 698.72 270
4 INT6665 Gene_expression of FOS 1 520 0.77 165.31 217.66
5 INT9852 Positive_regulation of Gpt 10 563 0.70 364.64 146.82
6 INT65600 Positive_regulation of Casp3 2 376 0.70 198.44 128.03
7 INT17612 Gene_expression of CRP 1 676 0.78 580.61 119.03
8 INT50674 Gene_expression of PTGS2 2 459 0.78 253.33 118.51
9 INT10838 Positive_regulation of IL8 4 381 0.70 295.51 101.62
10 INT17459 Positive_regulation of Gene_expression of FOS 1 182 0.67 53.45 96.38
11 INT77435 Positive_regulation of Nos2 6 343 0.70 208.49 91.43
12 INT10837 Positive_regulation of Gene_expression of IL8 5 294 0.70 190.08 70.34
13 INT17564 Gene_expression of Gpt 9 322 0.75 208.51 60.36
14 INT31116 Gene_expression of Casp3 1 192 0.78 78.21 57.43
15 INT5356 Positive_regulation of FOS 1 153 0.69 54.21 56.74
16 INT55135 Positive_regulation of Gene_expression of PTGS2 1 137 0.70 80.32 38.46
17 INT88318 Gene_expression of CXCR4 2 208 0.77 189.67 31.72
18 INT11650 Negative_regulation of Gpt 4 122 0.59 69.15 30.36
19 INT65597 Negative_regulation of Casp3 2 69 0.59 39.19 29.32
20 INT65598 Negative_regulation of Positive_regulation of Casp3 2 45 0.59 18.36 28.59
21 INT3286 Positive_regulation of Gpt 2 90 0.69 45.08 28.34
22 INT11361 Gene_expression of SERPINE1 1 183 0.78 136.45 27.97
23 INT21687 Positive_regulation of ras 6 143 0.58 97.34 27.31
24 INT17331 Positive_regulation of JUN 1 132 0.69 60.4 27.03
25 INT50490 Regulation of PTGS2 3 80 0.48 39.51 25.85
26 INT43486 Positive_regulation of Ifng 1 52 0.69 32.71 24.77
27 INT10835 Regulation of IL8 1 79 0.49 53.04 24.14
28 INT34488 Negative_regulation of MMP2 2 85 0.59 41.98 21.72
29 INT52107 Transcription of IL8 4 63 0.72 41.66 16.06
30 INT505 Positive_regulation of GPT 3 89 0.67 69.38 14.94
31 INT60197 Gene_expression of JUN 1 90 0.78 42.32 14.61
32 INT15246 Regulation of FOS 1 32 0.60 15.34 12.94
33 INT107033 Gene_expression of Slc37a4 3 66 0.62 27.34 12.35
34 INT81626 Positive_regulation of Positive_regulation of Casp3 1 34 0.69 16.75 12.18
35 INT93715 Negative_regulation of MMP9 2 69 0.55 36.05 11.73
36 INT97381 Negative_regulation of Positive_regulation of Nos2 2 34 0.59 16.66 11.6
37 INT118390 Positive_regulation of Nfe2l2 11 82 0.70 20.41 10.61
38 INT89282 Regulation of MMP9 2 39 0.60 25.45 10.34
39 INT2378 Negative_regulation of SERPINE1 2 47 0.59 34.55 9.9
40 INT62166 Positive_regulation of Gene_expression of Gpt 3 64 0.50 39.13 9.69
41 INT3287 Gene_expression of Gpt 9 50 0.75 23.69 8.57
42 INT83954 Binding of Cxcr2 1 21 0.37 17.27 7.65
43 INT22919 Negative_regulation of Gpt 1 18 0.55 6.84 7.4
44 INT75497 Regulation of JUN 1 28 0.61 11.04 7.09
45 INT3438 Negative_regulation of Dock7 3 11 0.00 1.03 6.72
46 INT9951 Gene_expression of ANGPTL5 1 45 0.53 37.2 6.44
47 INT29561 Binding of GSTM1 1 35 0.48 25.86 6.24
48 INT108628 Regulation of MMP2 2 27 0.60 14.85 6.06
49 INT75832 Positive_regulation of Positive_regulation of IL8 2 30 0.70 20.77 6.05
50 INT75831 Positive_regulation of Transcription of IL8 3 21 0.63 13.56 4.98
51 INT47451 Positive_regulation of Positive_regulation of ras 2 18 0.35 10.07 4.6
52 INT11634 Regulation of SERPINE1 5 24 0.62 20.06 4.26
53 INT64170 Gene_expression of GLI2 1 31 0.46 14.96 3.99
54 INT84430 Negative_regulation of Smpd1 1 22 0.59 10.33 3.95
55 INT81453 Positive_regulation of Gene_expression of JUN 1 18 0.50 9.39 3.23
56 INT112365 Regulation of HIF1A 3 27 0.60 21.24 3.05
57 INT162835 Positive_regulation of Cybb 1 38 0.68 16.09 3.02
58 INT113041 Gene_expression of IHH 4 9 0.78 5.83 2.87
59 INT118394 Positive_regulation of Positive_regulation of Nfe2l2 3 13 0.70 1.4 2.81
60 INT112364 Negative_regulation of HIF1A 2 22 0.57 16.95 2.13
61 INT54506 Gene_expression of KRR1 2 5 0.75 6.68 2.1
62 INT154651 Negative_regulation of Nfe2l2 2 19 0.59 10.48 2.01
63 INT48720 Transcription of SERPINE1 1 11 0.68 4.76 1.67
64 INT113111 Regulation of CXCR4 1 14 0.61 12.81 1.39
65 INT140296 Negative_regulation of XIAP 2 9 0.45 13.61 1.37
66 INT63223 Transcription of Gpt 3 4 0.65 3.38 1.27
67 INT3288 Positive_regulation of Gene_expression of Gpt 2 9 0.49 5.55 1.1
68 INT34692 Negative_regulation of Positive_regulation of ras 1 5 0.45 3.86 1.08
69 INT99767 Regulation of THBS1 3 18 0.42 11.51 1.03
70 INT165835 Positive_regulation of Lct 2 3 0.49 1.03 0.99
71 INT182211 Transcription of CXCR4 1 5 0.69 3.8 0.95
72 INT105697 Negative_regulation of KLK4 2 7 0.43 2.78 0.93
73 INT150108 Positive_regulation of Gene_expression of Slc37a4 1 5 0.35 2.09 0.83
74 INT154654 Positive_regulation of Keap1 2 4 0.68 1.55 0.82
75 INT95667 Positive_regulation of Nfkb2 1 3 0.22 3.95 0.8
76 INT240781 Negative_regulation of HGFAC 2 3 0.01 3.93 0.8
77 INT17051 Regulation of SERPINB2 2 2 0.41 2.41 0.74
78 INT165838 Positive_regulation of TBCE 1 3 0.07 1.3 0.71
79 INT169545 Positive_regulation of Negative_regulation of XIAP 1 1 0.00 1.15 0.67
80 INT252993 Negative_regulation of THBS1 2 8 0.55 6.93 0.59
81 INT96016 Negative_regulation of Lct 1 2 0.41 0.69 0.58
82 INT131597 Gene_expression of Keap1 1 17 0.76 6.65 0.55
83 INT9207 Negative_regulation of SERPINB2 2 2 0.38 2.34 0.51
84 INT165836 Positive_regulation of Positive_regulation of Lct 1 2 0.49 0.52 0.5
85 INT165839 Negative_regulation of Positive_regulation of TBCE 1 1 0.03 0.51 0.49
86 INT165837 Negative_regulation of Positive_regulation of Lct 1 1 0.41 0.51 0.49
87 INT156744 Gene_expression of Gpt2 8 1 0.72 5.1 0.49
88 INT150103 Negative_regulation of Gene_expression of Slc37a4 1 3 0.32 0.81 0.41
89 INT268558 Regulation of CTGF 2 5 0.23 4.7 0.37
90 INT150106 Gene_expression of Ugt1a7a-ps 3 1 0.09 0 0.35
91 INT154653 Negative_regulation of Positive_regulation of Keap1 1 2 0.36 0.59 0.34
92 INT137056 Regulation of Gene_expression of Gpt 2 9 0.39 3.92 0.33
93 INT40753 Gene_expression of GLI1 2 9 0.75 5.98 0.33
94 INT294475 Regulation of HAS2 2 1 0.07 2.03 0.33
95 INT294474 Negative_regulation of HAS2 2 1 0.25 1.87 0.29
96 INT294476 Negative_regulation of CTGF 2 1 0.27 1.86 0.29
97 INT154655 Negative_regulation of Negative_regulation of Nfe2l2 1 3 0.43 0.72 0.28
98 INT154656 Regulation of Keap1 1 2 0.46 1.9 0.25
99 INT132595 Binding of Gstt1 1 2 0.13 1.78 0.24
100 INT183062 Gene_expression of SHH 2 12 0.65 5.28 0.21
101 INT278241 Regulation of IHH 3 2 0.31 1.16 0.14
102 INT150107 Negative_regulation of Gck 1 2 0.31 0.89 0.12
103 INT150109 Gene_expression of Pdk4 1 2 0.53 3.79 0.12
104 INT150105 Positive_regulation of Gene_expression of Pdk4 1 2 0.41 2.96 0.12
105 INT114901 Binding of TBP 1 6 0.17 2.45 0.11
106 INT156747 Positive_regulation of Gpt2 1 1 0.43 0.21 0.1
107 INT156746 Negative_regulation of Gene_expression of Gpt2 1 1 0.40 0.59 0.09
108 INT156745 Localization of Gpt2 1 1 0.75 0.44 0.09
109 INT294471 Gene_expression of GLI4 2 1 0.48 0.94 0.08
110 INT183069 Gene_expression of DHH 1 2 0.50 0.87 0.06
111 INT150104 Regulation of Gene_expression of Ugt1a7a-ps 1 1 0.04 0 0.05
112 INT294468 Regulation of URGCP 1 1 0.00 0.2 0.04
113 INT294469 Transcription of THBS1 1 2 0.66 0.46 0.03
114 INT294473 Gene_expression of GLI3 1 1 0.37 0.63 0.03
115 INT294470 Transcription of IHH 1 1 0.16 0.28 0.03
116 INT287187 Regulation of TBP 1 3 0.13 2.42 0
117 INT294466 Positive_regulation of Rplp0 1 1 0.49 0 0
118 INT294465 Regulation of Rplp0 1 1 0.26 0.48 0
119 INT294464 Binding of Rplp0 1 1 0.36 0.73 0
120 INT294467 Transcription of DHH 1 1 0.32 0.45 0
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