J:Hum. Reprod.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT13098 POMC Regulation of Localization of CGA 1 2 0.58 0 1.14
2 INT60536 Gnrh1 Positive_regulation of Localization of Prl 2 1 0.22 1.12 0.6
3 INT60537 Gnrh1 Positive_regulation of Localization of FSHR 1 1 0.00 0.19 0.6
4 INT60538 Gnrh1 Positive_regulation of Localization of LHB 1 1 0.00 0.19 0.59
5 INT58356 Gabrg1 Regulation of Localization of Lhb 1 1 0.01 0 0.48
6 INT76154 Binding of NCOR2 and Negative_regulation of Localization of PLOD1 1 1 0.02 0 0.42
7 INT76153 Binding of NCOR2 and Negative_regulation of Localization of LHB 1 1 0.00 0 0.42
8 INT13097 POMC Negative_regulation of Localization of CGA 1 1 0.46 0 0.39
9 INT131020 Binding of GNRH1 and T1DM 1 1 0.10 0.99 0.08
10 INT138826 GNRH1 Regulation of Oprm1 1 1 0.01 0.07 0
11 INT138825 GNRH1 Regulation of Gene_expression of Oprm1 1 1 0.01 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT158 Localization of Prl 6 2431 0.81 378.96 952.2
2 INT443 Localization of POMC 7 1020 0.81 284.52 443.17
3 INT5895 Gene_expression of Oprm1 5 525 0.78 120.67 407.29
4 INT157 Positive_regulation of Localization of Prl 1 790 0.70 104.54 374.78
5 INT439 Localization of Gnrh1 1 976 0.81 100.96 363.25
6 INT720 Positive_regulation of POMC 1 807 0.70 237.37 353.83
7 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
8 INT162 Regulation of Prl 2 794 0.62 165.01 322.24
9 INT161 Regulation of Localization of Prl 4 615 0.62 65.37 298.66
10 INT10832 Gene_expression of IL8 3 1050 0.78 698.72 270
11 INT68684 Gene_expression of VEGFA 11 2371 0.78 1742.52 259.2
12 INT16868 Gene_expression of Il6 1 807 0.78 499.48 256.57
13 INT738 Regulation of POMC 2 459 0.62 111.19 243.74
14 INT767 Localization of Gnrhr 2 565 0.80 106.68 214.57
15 INT11313 Positive_regulation of Il6 1 526 0.70 331.27 201.59
16 INT156 Negative_regulation of Prl 4 542 0.59 131.97 192.24
17 INT528 Gene_expression of Prl 1 693 0.78 217.18 192.2
18 INT10194 Positive_regulation of IL6 2 702 0.70 600.62 183.38
19 INT12602 Negative_regulation of Oprm1 1 190 0.59 36.11 177.85
20 INT26472 Regulation of Oprm1 1 191 0.62 35.84 173.1
21 INT159 Negative_regulation of Localization of Prl 1 416 0.59 55.34 171.8
22 INT739 Negative_regulation of POMC 1 358 0.59 102.28 166.77
23 INT55879 Gene_expression of CCL2 6 421 0.78 240.74 166.02
24 INT5127 Localization of Lhb 3 488 0.80 50.48 162.66
25 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
26 INT6323 Positive_regulation of Gabrg1 1 213 0.70 45.08 124.34
27 INT50674 Gene_expression of PTGS2 1 459 0.78 253.33 118.51
28 INT7395 Localization of GNRH1 16 399 0.81 62.88 117.68
29 INT1438 Localization of Pomc 1 360 0.81 101.26 116.47
30 INT62124 Gene_expression of NOS1 2 444 0.78 218.08 114.85
31 INT48593 Positive_regulation of NOS1 1 420 0.68 226.15 114.71
32 INT1793 Localization of CGA 19 379 0.81 67.38 114.69
33 INT12082 Localization of IL6 1 365 0.81 241.78 105.78
34 INT2159 Regulation of Localization of Gnrh1 1 200 0.62 13.28 99.07
35 INT4860 Positive_regulation of CALCA 1 148 0.00 73.35 97.61
36 INT1639 Negative_regulation of OPRM1 1 107 0.59 13.86 90.37
37 INT914 Positive_regulation of GH1 2 292 0.69 100.7 84.91
38 INT16254 Positive_regulation of Gene_expression of Ngf 2 144 0.70 80.61 82.08
39 INT920 Localization of PLOD1 4 223 0.81 42.25 78.7
40 INT1335 Negative_regulation of Oprl1 1 123 0.59 18.02 77.13
41 INT12001 Regulation of Ngf 2 97 0.62 54.64 76.25
42 INT79494 Positive_regulation of Gene_expression of VEGFA 4 577 0.70 442.94 69.73
43 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
44 INT15613 Negative_regulation of Ptgs2 1 160 0.59 71.08 65.08
45 INT1794 Regulation of Localization of CGA 4 136 0.57 13.39 59.07
46 INT5710 Negative_regulation of Localization of Lhb 2 146 0.57 20.51 58.33
47 INT68813 Transcription of Oprm1 2 93 0.71 20.11 57.65
48 INT15091 Gene_expression of SLC6A4 1 101 0.78 29.91 53.64
49 INT921 Regulation of GH1 1 172 0.60 52.88 51.04
50 INT9210 Regulation of IL6 1 166 0.62 125.61 49.95
51 INT17881 Gene_expression of LEP 1 278 0.78 221.61 48.31
52 INT1197 Negative_regulation of Localization of POMC 1 109 0.59 28.29 48.02
53 INT789 Positive_regulation of YY1 1 69 0.67 14.07 47.06
54 INT81498 Positive_regulation of Gene_expression of CCL2 1 107 0.70 53.89 45.22
55 INT80124 Negative_regulation of VEGFA 1 450 0.58 311.19 44.53
56 INT50957 Negative_regulation of Il6 1 134 0.59 79.08 42.67
57 INT5130 Regulation of GNRH1 5 139 0.62 31.95 42.08
58 INT3933 Positive_regulation of PLOD1 1 128 0.70 30.76 42.03
59 INT957 Positive_regulation of GHRH 1 136 0.70 36.84 40.52
60 INT88081 Negative_regulation of Gene_expression of Oprm1 2 45 0.59 16.56 37.5
61 INT1361 Negative_regulation of Gnrhr 1 118 0.58 57.77 35.54
62 INT10796 Gene_expression of CYP2B6 2 131 0.77 30.14 35.27
63 INT79060 Gene_expression of NOS2 1 116 0.78 69.25 34.84
64 INT5868 Positive_regulation of GNRH1 2 122 0.69 20.96 32.8
65 INT7396 Regulation of Localization of GNRH1 3 81 0.62 6.57 31.31
66 INT10285 Binding of ADRA1D 1 102 0.47 25.82 31.11
67 INT99688 Negative_regulation of Gene_expression of VEGFA 2 274 0.58 201.8 31.1
68 INT65960 Gene_expression of BCL2 9 352 0.78 312.03 30.73
69 INT7975 Regulation of PLOD1 2 97 0.62 20.9 30.51
70 INT7397 Negative_regulation of Localization of GNRH1 3 86 0.59 15.45 29.78
71 INT15000 Transcription of Oprd1 1 32 0.72 5.7 29.22
72 INT6855 Binding of NCOR2 1 71 0.41 15.64 28.96
73 INT7035 Regulation of CGA 3 87 0.45 29.04 28.45
74 INT5135 Negative_regulation of GNRH1 5 106 0.58 36.63 27.71
75 INT5206 Gene_expression of AR 1 316 0.78 113.83 27.29
76 INT72677 Regulation of Gene_expression of Oprm1 1 45 0.62 13.95 26.75
77 INT1638 Negative_regulation of PLOD1 1 92 0.59 21.69 26.61
78 INT3559 Negative_regulation of Localization of Gnrhr 1 73 0.58 18.89 26.41
79 INT2261 Gene_expression of Lhb 1 121 0.77 42.78 26.04
80 INT7394 Positive_regulation of Localization of GNRH1 3 67 0.69 7.22 25.29
81 INT4877 Gene_expression of MME 1 184 0.78 122.82 24.78
82 INT2614 Gene_expression of CGA 7 187 0.78 105.89 24.77
83 INT10836 Negative_regulation of IL8 1 95 0.59 52.59 24.71
84 INT79061 Positive_regulation of NOS2 2 92 0.65 58.89 23.96
85 INT5131 Gene_expression of GNRH1 4 109 0.78 28.79 23.94
86 INT4465 Gene_expression of CEL 1 116 0.77 98.35 23.58
87 INT35716 Positive_regulation of NCOR2 1 45 0.60 18 23.54
88 INT250 Regulation of GHRH 2 65 0.61 17.46 23.19
89 INT917 Positive_regulation of Localization of PLOD1 1 51 0.69 8.53 22.87
90 INT4612 Positive_regulation of Localization of CGA 1 64 0.64 8.51 22.39
91 INT71047 Gene_expression of CYP19A1 3 122 0.78 68.78 22.21
92 INT2386 Gene_expression of Pgr 1 112 0.78 45.46 22.19
93 INT3589 Positive_regulation of SCN5A 1 101 0.57 46.01 21.73
94 INT1644 Regulation of FSHR 4 77 0.55 15.62 21.49
95 INT1792 Positive_regulation of CGA 3 123 0.70 64.73 20.79
96 INT82434 Positive_regulation of LEP 4 117 0.70 95.45 20.22
97 INT68683 Regulation of Gene_expression of VEGFA 5 143 0.62 104.19 20.14
98 INT5372 Localization of LHB 4 55 0.68 9.47 19
99 INT1642 Negative_regulation of Localization of PLOD1 2 40 0.58 10.67 17.95
100 INT6782 Gene_expression of SCN5A 1 156 0.78 33.13 17.88
101 INT4769 Regulation of OPRD1 1 20 0.44 2.05 15.97
102 INT912 Localization of FSHR 1 91 0.79 23.61 15.58
103 INT26538 Positive_regulation of FSHR 6 103 0.69 30.95 15.33
104 INT11918 Localization of CGB 1 35 0.51 8.21 15.01
105 INT4145 Gene_expression of FSHR 2 124 0.77 44.98 13.04
106 INT83201 Gene_expression of NOS3 1 93 0.78 47.16 12.48
107 INT7234 Binding of GNRH1 1 43 0.47 21.59 12.36
108 INT3104 Negative_regulation of CGA 5 76 0.54 29.81 12.23
109 INT520 Binding of Comt 1 24 0.48 8.98 12.21
110 INT8547 Gene_expression of MUC16 5 116 0.78 75.97 12.18
111 INT5045 Regulation of VIP 1 26 0.62 7.15 11.61
112 INT8546 Positive_regulation of MUC16 5 99 0.69 74.98 11.26
113 INT9946 Regulation of Localization of LHB 3 27 0.52 2.47 11.08
114 INT73223 Gene_expression of UPF1 1 78 0.41 31.44 9.94
115 INT1648 Regulation of LHB 1 21 0.61 3.32 9.6
116 INT1647 Negative_regulation of FSHR 1 54 0.45 13.44 8.87
117 INT591 Negative_regulation of Serpinc1 1 44 0.57 31.73 8.82
118 INT75907 Binding of LEP 1 53 0.46 46.65 8.44
119 INT13346 Regulation of Localization of CGB 1 18 0.30 1.29 8.32
120 INT65959 Positive_regulation of Gene_expression of BCL2 4 75 0.70 77.3 8.27
121 INT7588 Regulation of NPY 1 13 0.44 6.97 7.97
122 INT76091 Positive_regulation of NOS3 1 48 0.61 18.4 7.92
123 INT39417 Gene_expression of Fcer2a 1 65 0.76 32.1 7.37
124 INT78404 Gene_expression of COX5A 1 24 0.75 9.73 7.07
125 INT79062 Gene_expression of B4GALNT1 1 42 0.14 18.89 6.98
126 INT31333 Gene_expression of Esr2 1 19 0.69 8.78 6.83
127 INT50712 Gene_expression of Comt 1 13 0.68 6.33 6.23
128 INT4144 Gene_expression of SHBG 1 64 0.68 39.94 6.08
129 INT16568 Positive_regulation of HTR3A 1 14 0.67 4.82 6.01
130 INT4629 Regulation of Fshb 1 12 0.49 1.93 5.95
131 INT70613 Negative_regulation of Gene_expression of BCL2 1 48 0.59 38.91 5.22
132 INT14715 Negative_regulation of Positive_regulation of CALCA 1 5 0.43 2.22 5.2
133 INT924 Regulation of Localization of FSHR 1 15 0.45 1.4 5.07
134 INT23245 Positive_regulation of Gene_expression of CEL 1 19 0.69 14.81 4.92
135 INT5205 Localization of AR 4 43 0.80 12.87 4.63
136 INT14714 Negative_regulation of NPY 1 10 0.58 4.41 4.52
137 INT70756 Gene_expression of Adm 2 28 0.77 13.33 4.22
138 INT11370 Positive_regulation of LHB 1 15 0.28 5.45 4.01
139 INT119641 Gene_expression of EBAG9 2 25 0.76 33.2 3.96
140 INT11230 Regulation of MUC16 2 23 0.60 19.54 3.93
141 INT5204 Positive_regulation of Gene_expression of AR 1 60 0.67 23.54 3.53
142 INT4632 Regulation of CGB 1 9 0.38 1.81 3.53
143 INT78284 Positive_regulation of PTPRC 1 40 0.49 27.17 3.45
144 INT13347 Regulation of Negative_regulation of OPRM1 1 5 0.45 0.64 3.38
145 INT15609 Positive_regulation of Gene_expression of GNRH1 2 17 0.49 5.15 3.34
146 INT66617 Localization of HTR2A 1 6 0.80 1.35 3.32
147 INT53889 Negative_regulation of Positive_regulation of YY1 1 6 0.41 0.57 3.05
148 INT50765 Positive_regulation of Fcer2a 2 23 0.68 10.22 2.92
149 INT4147 Gene_expression of LHB 1 8 0.49 3.94 2.88
150 INT45112 Positive_regulation of PRB1 1 20 0.60 6.49 2.85
151 INT8095 Gene_expression of ERBB3 3 47 0.77 24.85 2.82
152 INT919 Regulation of Positive_regulation of GH1 1 7 0.47 1.09 2.75
153 INT16715 Positive_regulation of Transcription of Oprd1 1 3 0.66 0.6 2.74
154 INT91594 Localization of NOS3 1 12 0.78 5.39 2.02
155 INT19409 Binding of Cyp1a1 1 12 0.48 2.58 1.97
156 INT15576 Regulation of Regulation of GNRH1 1 4 0.34 0.27 1.97
157 INT119639 Gene_expression of KIR3DL1 3 5 0.77 2.96 1.91
158 INT11033 Positive_regulation of Gene_expression of MUC16 1 21 0.69 15.75 1.89
159 INT43479 Positive_regulation of Positive_regulation of CGA 1 9 0.39 4.24 1.46
160 INT11887 Localization of MUC16 1 16 0.80 10.66 1.26
161 INT13674 Gene_expression of Cyp1a1 1 13 0.65 2.22 1.25
162 INT81757 Regulation of Gene_expression of Adm 2 6 0.44 2.86 1.16
163 INT119638 Gene_expression of KIR2DL3 3 6 0.75 1.35 0.69
164 INT11032 Positive_regulation of Positive_regulation of MUC16 1 2 0.49 2.38 0.67
165 INT61025 Negative_regulation of Negative_regulation of Il6 1 3 0.43 1.15 0.56
166 INT14713 Negative_regulation of Regulation of VIP 1 1 0.33 0.09 0.56
167 INT7067 Negative_regulation of Gene_expression of SHBG 1 7 0.41 5.08 0.48
168 INT55850 Negative_regulation of Positive_regulation of CGA 1 2 0.55 0.08 0.46
169 INT73100 Negative_regulation of PADI4 1 3 0.57 3.42 0.37
170 INT131019 Binding of T2DM 1 6 0.47 6.97 0.31
171 INT116997 Gene_expression of Il18r1 3 3 0.04 0.82 0.26
172 INT134130 Gene_expression of CYP17A1 1 2 0.65 2.38 0.26
173 INT74138 Positive_regulation of Negative_regulation of KCNC4 1 1 0.45 0.1 0.26
174 INT74137 Negative_regulation of KCNC4 1 1 0.57 0.1 0.25
175 INT68847 Gene_expression of FCGRT 1 3 0.58 0.91 0.2
176 INT57198 Negative_regulation of Positive_regulation of SCN5A 1 2 0.30 0.17 0.12
177 INT134131 Binding of CYP17A1 1 1 0.36 0.12 0
178 INT119635 Gene_expression of Klrd1 2 1 0.07 0.37 0
179 INT119637 Negative_regulation of Gene_expression of KIR2DL3 1 1 0.07 0.17 0
180 INT119640 Negative_regulation of Gene_expression of KIR3DL1 1 1 0.17 0.17 0
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