J:Human Genomics and Proteomics : HGP

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 1 0.00 0.54 1.04
2 INT338892 TNFSF14 Regulation of Abat 1 1 0.00 0.61 1.01
3 INT338895 TNFSF14 Regulation of Regulation of Abat 1 1 0.00 0.62 1.01
4 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 1 0.07 0.59 0.94
5 INT338940 Fpgs Positive_regulation of Mtx1 1 1 0.32 0.32 0.47
6 INT338941 Binding of Ggh and Mtx1 1 1 0.30 0.47 0.27
7 INT338898 Binding of PECAM1 and PTPN11 1 2 0.04 0.38 0.19
8 INT338901 Binding of PECAM1 and PTPN6 1 1 0.03 0.18 0.1
9 INT338902 Binding of MAX and MYC 1 1 0.02 0.23 0.06
10 INT338900 MYC Positive_regulation of Gene_expression of TP73 1 1 0.05 0.27 0.03
11 INT338899 THPO Positive_regulation of STAT3 1 1 0.16 0 0
12 INT338896 Binding of JUN and Jun 1 1 0.01 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT16260 Gene_expression of Bdnf 2 671 0.78 283.44 339.1
2 INT2909 Positive_regulation of Abat 1 334 0.70 62.1 256.43
3 INT9987 Gene_expression of Abat 2 296 0.78 95.46 226.34
4 INT11009 Phosphorylation of Creb1 2 458 0.82 111.34 221.97
5 INT16259 Positive_regulation of Bdnf 3 336 0.70 183.48 209.82
6 INT2910 Regulation of Abat 2 169 0.62 36.95 153.53
7 INT16253 Positive_regulation of Gene_expression of Bdnf 1 196 0.70 92.67 113.01
8 INT11011 Positive_regulation of Phosphorylation of Creb1 1 190 0.70 49.25 112.01
9 INT49651 Gene_expression of Creb1 1 276 0.78 114.77 111.96
10 INT29708 Gene_expression of Gria1 1 177 0.78 56.36 77.37
11 INT24989 Positive_regulation of Cfp 1 125 0.61 29.55 64.9
12 INT47690 Regulation of Bdnf 1 118 0.62 53.02 64.5
13 INT88617 Positive_regulation of Gene_expression of Creb1 1 90 0.69 51.69 44.29
14 INT47683 Negative_regulation of Bdnf 1 92 0.59 47.53 43.55
15 INT12228 Positive_regulation of Gene_expression of Abat 2 44 0.65 17.51 40.55
16 INT11560 Positive_regulation of CASP3 1 236 0.70 184.33 39.38
17 INT16714 Regulation of Creb1 1 64 0.62 22.23 33.56
18 INT45365 Negative_regulation of Cfp 1 68 0.57 25.44 32.11
19 INT145594 Gene_expression of Mtx1 4 64 0.57 35.33 30.35
20 INT17331 Positive_regulation of JUN 1 132 0.69 60.4 27.03
21 INT12484 Binding of Drd2 1 45 0.48 15.17 24.72
22 INT71781 Phosphorylation of MAPK3 2 62 0.80 27.73 23.73
23 INT11346 Binding of Mtx1 3 39 0.41 24.88 21.21
24 INT49774 Binding of DRD2 1 48 0.48 17.42 20.73
25 INT12725 Positive_regulation of Racgap1 1 66 0.68 32.74 19.29
26 INT61158 Negative_regulation of Creb1 1 33 0.59 11.54 18.06
27 INT133647 Negative_regulation of HDAC9 1 149 0.57 106.84 17.9
28 INT65659 Positive_regulation of STAT3 1 132 0.70 69.56 15.95
29 INT60197 Gene_expression of JUN 1 90 0.78 42.32 14.61
30 INT20420 Gene_expression of MYC 2 99 0.75 49.32 14.36
31 INT108063 Gene_expression of Adora2a 4 29 0.78 13.11 13.78
32 INT16713 Binding of Creb1 2 53 0.48 20.24 13.06
33 INT39016 Transcription of Abat 2 19 0.53 3.92 10.82
34 INT60198 Binding of JUN 1 54 0.48 11.56 10.27
35 INT68372 Regulation of CYP2C9 1 28 0.62 5.64 9.53
36 INT137400 Regulation of Mtx1 2 16 0.52 9.19 9.45
37 INT46273 Gene_expression of PRNP 2 103 0.78 110.34 9.25
38 INT22285 Negative_regulation of Mtx1 1 16 0.49 7.84 8.98
39 INT44378 Gene_expression of GSTM1 1 69 0.76 34.61 8.81
40 INT66819 Binding of CYP2C9 1 41 0.48 8.23 8.76
41 INT70017 Positive_regulation of BCL2 1 87 0.67 66.62 8.68
42 INT61599 Positive_regulation of CYP2C9 1 43 0.69 11.1 8.33
43 INT73544 Gene_expression of Grm7 2 34 0.64 31.28 8.04
44 INT24232 Localization of Mtx1 3 24 0.65 8.06 7.99
45 INT54978 Binding of EDNRA 1 36 0.41 14.97 7.86
46 INT91930 Gene_expression of Kcnab3 1 10 0.16 4.41 7.77
47 INT17501 Negative_regulation of F2 1 70 0.58 32.23 7.51
48 INT75497 Regulation of JUN 1 28 0.61 11.04 7.09
49 INT34767 Gene_expression of PTGIR 1 36 0.42 14.79 6.69
50 INT24460 Localization of Drd2 1 12 0.73 2.96 6.46
51 INT69561 Positive_regulation of GSTM1 1 23 0.50 5.69 6.36
52 INT29561 Binding of GSTM1 1 35 0.48 25.86 6.24
53 INT79737 Positive_regulation of Ntrk1 1 12 0.49 3.98 6.24
54 INT138671 Gene_expression of TPH2 1 35 0.78 7.34 6.03
55 INT38686 Binding of NR3C1 1 20 0.48 9.25 5.99
56 INT134544 Negative_regulation of Positive_regulation of CASP3 1 23 0.57 18.48 5.95
57 INT139560 Gene_expression of Tph2 1 9 0.78 2.33 5.46
58 INT110666 Phosphorylation of Bdnf 1 12 0.69 5.67 5.21
59 INT2162 Regulation of Comt 1 13 0.60 2.9 5.18
60 INT86219 Negative_regulation of GSTK1 3 25 0.41 8.99 4.97
61 INT124375 Gene_expression of Wnt2 1 67 0.56 38.03 4.67
62 INT24011 Binding of Drd3 1 13 0.47 3.03 4.64
63 INT128746 Negative_regulation of Gsk3a 5 11 0.52 8.43 4.61
64 INT66366 Positive_regulation of Gsk3b 1 15 0.68 6.56 4.27
65 INT51898 Binding of PECAM1 1 26 0.36 18.87 4.22
66 INT57645 Gene_expression of GSTK1 7 54 0.62 21.05 4.2
67 INT121818 Binding of STAT3 1 25 0.47 11.16 3.67
68 INT130295 Gene_expression of Abcg2 2 21 0.75 9.75 3.42
69 INT118761 Positive_regulation of Per2 1 9 0.42 0.68 3.33
70 INT60541 Regulation of GSTK1 2 12 0.61 6.76 3.31
71 INT134413 Gene_expression of HPGDS 1 20 0.77 8.93 3.28
72 INT227515 Regulation of Gene_expression of Mtx1 1 5 0.38 4.34 3.24
73 INT15253 Binding of DBH 1 7 0.36 3.21 3.17
74 INT8103 Binding of TP53 1 46 0.44 40.2 2.96
75 INT63112 Binding of Hrh1 3 6 0.17 3.83 2.76
76 INT119516 Positive_regulation of Phosphorylation of Bdnf 1 3 0.21 2.81 2.68
77 INT14447 Localization of F2 1 20 0.79 12.77 2.67
78 INT254118 Negative_regulation of Gene_expression of Adora2a 4 3 0.42 2.54 2.43
79 INT92000 Gene_expression of Gsk3a 1 12 0.18 4.12 2.39
80 INT34796 Positive_regulation of TNFSF14 1 7 0.67 4.16 2.26
81 INT134944 Gene_expression of MOCS1 1 37 0.06 10.76 2.17
82 INT163713 Negative_regulation of Tph2 1 4 0.59 1.4 2.13
83 INT105008 Binding of DRD3 1 5 0.36 3.15 2.05
84 INT101243 Regulation of STAT3 1 12 0.62 9.98 1.92
85 INT20421 Positive_regulation of MYC 1 19 0.67 10.43 1.9
86 INT187492 Positive_regulation of ATIC 1 9 0.05 1.74 1.88
87 INT111675 Regulation of TNFSF14 2 3 0.26 3.41 1.85
88 INT138670 Negative_regulation of Gene_expression of TPH2 1 3 0.42 0.91 1.69
89 INT91928 Positive_regulation of Gene_expression of Kcnab3 1 2 0.06 0.89 1.69
90 INT78202 Binding of GSTK1 2 17 0.31 5.44 1.66
91 INT124418 Gene_expression of Mthfr 1 4 0.60 4.52 1.54
92 INT247263 Regulation of Mecp2 2 4 0.60 1.31 1.32
93 INT163506 Binding of Gsk3a 1 4 0.32 1.41 1.31
94 INT68359 Positive_regulation of HPGDS 1 9 0.32 4.63 1.18
95 INT103240 Negative_regulation of Tyms 1 4 0.57 1.7 0.99
96 INT164324 Negative_regulation of Gene_expression of Abcg2 1 4 0.45 1.03 0.99
97 INT82795 Binding of MYC 1 16 0.47 6.1 0.9
98 INT261360 Binding of Gsk3b 1 5 0.36 2.85 0.9
99 INT91995 Positive_regulation of Gsk3a 1 8 0.14 2.84 0.86
100 INT137284 Gene_expression of Vkorc1 1 2 0.33 0.54 0.85
101 INT69913 Binding of ATF2 1 6 0.13 0.83 0.84
102 INT190089 Binding of Abca1 1 5 0.36 2.21 0.83
103 INT307469 Regulation of Gsk3a 2 4 0.09 1.12 0.83
104 INT24234 Positive_regulation of Localization of Mtx1 1 2 0.34 0.32 0.77
105 INT137286 Regulation of Vkorc1 1 2 0.30 0.56 0.75
106 INT338858 Regulation of HADHA 1 1 0.03 0.61 0.72
107 INT338863 Positive_regulation of HADHA 1 1 0.03 0.61 0.72
108 INT108170 Gene_expression of Tyms 1 6 0.69 1.97 0.71
109 INT72981 Positive_regulation of Scg2 2 3 0.45 1.05 0.71
110 INT35048 Localization of TNFSF14 1 5 0.68 3.12 0.66
111 INT338936 Negative_regulation of Localization of Mtx1 1 2 0.30 1.08 0.64
112 INT70025 Positive_regulation of Positive_regulation of BCL2 1 3 0.27 0.96 0.58
113 INT338929 Gene_expression of Slc19a1 2 1 0.62 0.65 0.57
114 INT242168 Transcription of JUP 1 4 0.67 1.17 0.46
115 INT307472 Regulation of Negative_regulation of Gsk3a 2 2 0.05 0.83 0.45
116 INT338935 Binding of Itpa 1 1 0.08 0.93 0.45
117 INT338888 Positive_regulation of Transcription of Abat 2 1 0.03 0.13 0.44
118 INT338868 Binding of Mc2r 1 1 0.02 0.38 0.44
119 INT134412 Binding of HPGDS 3 9 0.42 1.7 0.43
120 INT302180 Positive_regulation of Gene_expression of Abcg2 1 6 0.61 3.13 0.43
121 INT162049 Phosphorylation of F2 1 3 0.47 0.99 0.39
122 INT338931 Binding of Slco1b2 1 1 0.05 0.47 0.39
123 INT338937 Positive_regulation of Gene_expression of Fpgs 1 1 0.48 0.13 0.37
124 INT338933 Gene_expression of Fpgs 1 1 0.54 0.13 0.37
125 INT113283 Negative_regulation of Tyms 1 2 0.41 0.4 0.35
126 INT338882 Regulation of Regulation of Mecp2 2 1 0.24 0.56 0.29
127 INT338928 Binding of Ggh 1 1 0.30 0.46 0.27
128 INT338875 Negative_regulation of Gene_expression of Tph2 1 1 0.17 0.44 0.26
129 INT252757 Negative_regulation of PTPN6 1 4 0.10 0.74 0.25
130 INT223645 Positive_regulation of Gene_expression of Grm7 1 2 0.25 1.16 0.21
131 INT111803 Phosphorylation of PLCG1 1 2 0.17 0.14 0.21
132 INT338934 Negative_regulation of Slc46a1 1 1 0.40 0.15 0.2
133 INT154147 Gene_expression of TP73 1 7 0.34 3.97 0.19
134 INT144005 Negative_regulation of PRKCB 1 2 0.28 0.2 0.19
135 INT338874 Binding of Fyn 1 1 0.08 0.53 0.19
136 INT338861 Positive_regulation of SIX1 1 1 0.13 0.47 0.18
137 INT338841 Regulation of Polr2a 1 1 0.01 0.08 0.17
138 INT338840 Protein_catabolism of Polr2a 1 1 0.02 0.08 0.17
139 INT113346 Binding of MDM2 2 10 0.35 5.73 0.15
140 INT318673 Negative_regulation of Xbp1 1 3 0.41 1.51 0.15
141 INT338869 Regulation of Regulation of Fmr1 1 1 0.11 0.29 0.15
142 INT338872 Regulation of Regulation of Creb1 1 1 0.21 0.28 0.15
143 INT338857 Gene_expression of SIX1 1 1 0.22 0.42 0.14
144 INT338870 Regulation of Fmr1 1 1 0.14 0.29 0.14
145 INT327818 Binding of GPRC6A 2 3 0.01 0.28 0.13
146 INT338915 Positive_regulation of Phosphorylation of PLCG1 1 1 0.13 0.06 0.12
147 INT218018 Regulation of Gene_expression of GSTK1 1 5 0.37 2.74 0.11
148 INT241305 Binding of PTPN11 1 9 0.46 6.08 0.1
149 INT267568 Negative_regulation of PTPN11 1 7 0.28 0.36 0.1
150 INT338914 Negative_regulation of Phosphorylation of CRK 1 1 0.08 0 0.1
151 INT338859 Binding of DGKH 3 1 0.35 2.45 0.1
152 INT338913 Phosphorylation of CRK 1 1 0.12 0 0.1
153 INT338877 Negative_regulation of Impa1 1 1 0.19 0.08 0.1
154 INT315092 Regulation of MIR34A 1 4 0.26 1.29 0.09
155 INT338884 Regulation of Grm7 1 1 0.13 0.42 0.09
156 INT338881 Regulation of Mir221 1 1 0.03 0.32 0.09
157 INT338883 Positive_regulation of Regulation of Grm7 1 1 0.22 0.42 0.09
158 INT175757 Positive_regulation of PER2 1 6 0.67 0.44 0.05
159 INT338873 Binding of Ank3 1 1 0.12 0.55 0.05
160 INT338891 Positive_regulation of Impa1 1 1 0.22 0.08 0.05
161 INT338942 Regulation of Gene_expression of Vkorc1 1 1 0.22 0 0.04
162 INT338876 Binding of Xbp1 1 1 0.18 0.32 0.04
163 INT172624 Binding of NCOA3 1 4 0.22 1.05 0.03
164 INT338871 Negative_regulation of Inpp1 1 1 0.18 0 0.03
165 INT338885 Gene_expression of Inpp1 1 1 0.33 0 0.03
166 INT338947 Regulation of GPRC6A 1 1 0.01 0.13 0
167 INT338860 Positive_regulation of PAFAH1B2 1 1 0.20 0.06 0
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