J:Immunome Res

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 1 0.25 1.3 1.12
2 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 1 0.14 3.53 0.9
3 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 1 0.32 1.93 0.78
4 INT233527 Tlr4 Positive_regulation of ADORA1 1 1 0.00 0.45 0.47
5 INT233503 Tlr4 Positive_regulation of Adora2b 1 1 0.06 0.45 0.47
6 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 1 0.04 0.45 0.46
7 INT233513 Pklr Negative_regulation of Localization of Il10 1 2 0.04 1.12 0.39
8 INT233515 Pklr Positive_regulation of Gene_expression of Tnf 1 2 0.05 1.12 0.27
9 INT233507 Tlr4 Regulation of Prokr1 1 1 0.04 0.48 0.2
10 INT233525 Tlr4 Regulation of Itm2b 1 1 0.00 0.48 0.2
11 INT233511 Tlr4 Negative_regulation of Transcription of Lpar6 1 1 0.05 0.1 0.15
12 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 1 0.03 0.33 0.1
13 INT233519 Binding of S1pr1 and S1pr2 1 1 0.13 0.2 0.08
14 INT233522 Tlr4 Positive_regulation of Gene_expression of Prokr1 1 1 0.08 0.44 0.07
15 INT233521 Binding of Pklr and Prokr1 1 1 0.17 0.44 0.07
16 INT233502 Fzd5 Positive_regulation of Gene_expression of Il12a 1 1 0.04 0.33 0.07
17 INT233514 Tlr4 Positive_regulation of Prokr1 1 2 0.10 0.45 0.05
18 INT233518 Tlr4 Positive_regulation of Itm2b 1 1 0.00 0.38 0.05
19 INT233506 Tlr4 Positive_regulation of Htr2b 1 1 0.06 0.09 0
20 INT233501 Itm2b Positive_regulation of Transcription of Gpr84 1 1 0.02 0.1 0
21 INT233504 Tlr4 Regulation of P2ry2 1 1 0.04 0.07 0
22 INT233520 Tlr4 Positive_regulation of Fzd1 1 1 0.03 0.09 0
23 INT233526 Tlr4 Regulation of Adrb2 1 1 0.03 0.07 0
24 INT233516 Tlr4 Regulation of Gpr18 1 1 0.04 0.07 0
25 INT233500 Tlr4 Negative_regulation of P2ry1 1 2 0.06 0.18 0
26 INT233523 Tlr4 Regulation of P2ry12 1 1 0.04 0.07 0
27 INT233517 Tlr4 Regulation of Gpr85 1 1 0.09 0 0
28 INT233509 Tlr4 Regulation of Gene_expression of Gprc5b 1 1 0.04 0.07 0
29 INT233505 Tlr4 Positive_regulation of Gpr84 1 1 0.11 0.09 0
30 INT233524 Negative_regulation of Tlr4 Positive_regulation of Gpr84 1 1 0.07 0.09 0
31 INT233512 Tlr4 Positive_regulation of Transcription of Gpr84 1 2 0.07 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3 3152 0.78 2515.62 929.82
2 INT10832 Gene_expression of IL8 1 1050 0.78 698.72 270
3 INT6488 Gene_expression of Tnf 2 484 0.78 339.61 191.58
4 INT60694 Gene_expression of Il10 1 567 0.78 369.48 143.69
5 INT7533 Gene_expression of Tlr4 6 720 0.78 343.22 121.57
6 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
7 INT60691 Gene_expression of Il12a 4 331 0.78 208.03 75.96
8 INT10837 Positive_regulation of Gene_expression of IL8 1 294 0.70 190.08 70.34
9 INT11937 Localization of Il6 1 228 0.81 139.83 64.39
10 INT65730 Gene_expression of Cnr2 1 129 0.78 60.15 63.1
11 INT1951 Positive_regulation of Tlr4 1 345 0.70 176.99 62.42
12 INT168410 Gene_expression of Cxcr3 3 81 0.75 84.03 37.01
13 INT81289 Positive_regulation of Gene_expression of Tlr4 3 192 0.69 104.5 33.89
14 INT77652 Negative_regulation of Gene_expression of IL8 1 99 0.59 67.57 30.21
15 INT90792 Localization of Il10 2 144 0.80 87.88 30.03
16 INT233457 Gene_expression of Gpr65 1 56 0.68 26.57 27.94
17 INT141612 Gene_expression of Ccr1 4 92 0.77 72.09 24.14
18 INT7535 Negative_regulation of Tlr4 1 111 0.56 56.84 21.37
19 INT49985 Transcription of Il6 1 62 0.72 40.13 20.29
20 INT102545 Gene_expression of Ccr2 5 42 0.78 61.43 19.81
21 INT118512 Gene_expression of F2r 1 33 0.63 26.56 18.26
22 INT11938 Positive_regulation of Localization of Il6 1 61 0.70 35.72 18.25
23 INT125947 Gene_expression of Adora2b 1 57 0.75 23.69 17
24 INT43906 Regulation of Tlr4 2 71 0.53 35.18 15.49
25 INT99784 Positive_regulation of Cxcr3 1 22 0.66 22.44 10.36
26 INT161222 Positive_regulation of Ccr2 1 13 0.55 13.77 8.89
27 INT135578 Gene_expression of Prokr1 1 22 0.70 11.71 8.31
28 INT168642 Gene_expression of Cx3cr1 3 15 0.77 21.73 8.1
29 INT166881 Positive_regulation of Ccr1 2 31 0.69 18.14 7.9
30 INT9350 Regulation of ADORA1 1 9 0.12 1.53 7.79
31 INT111680 Gene_expression of P2ry2 5 20 0.58 9.23 7.39
32 INT146055 Gene_expression of Gpr68 1 3 0.63 8.12 6.99
33 INT141611 Positive_regulation of Gene_expression of Ccr1 2 25 0.69 20.32 6.42
34 INT126481 Gene_expression of Cxcr4 3 69 0.77 34.99 6
35 INT103760 Regulation of Gene_expression of Tlr4 1 35 0.59 16.26 5.95
36 INT148968 Gene_expression of Gpbar1 11 29 0.56 11.9 5.66
37 INT111683 Gene_expression of P2ry1 2 22 0.74 7.96 5.59
38 INT233493 Gene_expression of Ccrl2 6 59 0.65 11.61 4.71
39 INT174427 Positive_regulation of Gene_expression of Cxcr3 2 8 0.66 10.7 4.66
40 INT29519 Gene_expression of Ednrb 1 8 0.66 1.99 4.55
41 INT165182 Gene_expression of P2ry12 1 4 0.65 4.29 4.08
42 INT161221 Positive_regulation of Positive_regulation of Ccr2 1 3 0.50 4.55 3.98
43 INT142984 Positive_regulation of S1pr1 1 13 0.70 7.9 3.84
44 INT168639 Positive_regulation of Cx3cr1 1 7 0.57 8.57 3.67
45 INT66924 Positive_regulation of Transcription of Il6 1 18 0.68 11.8 3.53
46 INT194848 Negative_regulation of Localization of Il10 2 11 0.36 8.29 3.38
47 INT228043 Gene_expression of Fpr3 1 3 0.51 33.57 2.78
48 INT215521 Negative_regulation of P2ry1 1 10 0.56 2.68 2.72
49 INT136522 Negative_regulation of Prokr1 2 9 0.58 3.53 2.71
50 INT128774 Regulation of Gene_expression of Ednrb 1 3 0.46 1 2.56
51 INT107846 Transcription of P2ry2 1 6 0.46 2.06 2.52
52 INT168638 Positive_regulation of Gene_expression of Cx3cr1 2 6 0.65 5.15 2.19
53 INT181015 Gene_expression of C3ar1 1 12 0.58 8.9 2.18
54 INT224047 Regulation of Adora2b 1 7 0.27 3.23 2.12
55 INT233458 Gene_expression of Gpr18 1 2 0.66 1.75 2.11
56 INT114434 Gene_expression of Calcrl 2 10 0.78 5.81 1.83
57 INT102348 Regulation of P2ry2 1 6 0.40 2.18 1.79
58 INT126476 Positive_regulation of Cxcr4 2 25 0.69 19.01 1.72
59 INT111682 Transcription of P2ry1 2 4 0.52 1.26 1.71
60 INT174425 Positive_regulation of Positive_regulation of Cxcr3 1 3 0.48 3.05 1.71
61 INT102550 Positive_regulation of Gene_expression of Ccr2 2 6 0.69 4.53 1.67
62 INT233488 Gene_expression of P2ry14 2 3 0.71 1.67 1.57
63 INT184359 Gene_expression of C5ar1 1 6 0.55 5.48 1.34
64 INT117966 Binding of P2ry2 1 5 0.36 0.44 1.31
65 INT91555 Positive_regulation of Gpr18 1 3 0.40 0.63 1.14
66 INT152225 Regulation of Positive_regulation of Tlr4 1 8 0.53 2.5 1.12
67 INT233466 Positive_regulation of Transcription of P2ry6 6 1 0.40 2.52 1.09
68 INT233456 Gene_expression of P2ry6 4 5 0.66 1.74 1.04
69 INT233471 Gene_expression of Gpr84 11 1 0.68 3.01 1.04
70 INT233453 Gene_expression of Itm2b 7 8 0.74 8.45 0.99
71 INT233450 Gene_expression of Cd97 1 2 0.54 1.45 0.95
72 INT233482 Positive_regulation of Gene_expression of P2ry2 3 4 0.43 0.76 0.92
73 INT217050 Positive_regulation of Gene_expression of Adora2b 1 3 0.50 1.19 0.92
74 INT226691 Positive_regulation of Gene_expression of Cxcr4 2 14 0.57 7.9 0.9
75 INT233474 Positive_regulation of P2ry6 3 4 0.40 2.04 0.84
76 INT169710 Gene_expression of Gpr35 1 13 0.67 5.27 0.78
77 INT233497 Positive_regulation of Ccrl2 1 2 0.58 2.7 0.74
78 INT233469 Transcription of P2ry6 5 1 0.45 2.02 0.73
79 INT10179 Gene_expression of Fpr1 1 5 0.48 0.54 0.66
80 INT233464 Binding of S1pr1 1 2 0.28 1.81 0.66
81 INT233460 Binding of P2ry14 2 3 0.34 0.3 0.56
82 INT233484 Positive_regulation of Gene_expression of P2ry1 3 4 0.43 0.95 0.5
83 INT233496 Regulation of Gene_expression of Gpbar1 6 1 0.21 1.34 0.5
84 INT233489 Regulation of Gene_expression of Ccrl2 1 4 0.38 0.74 0.49
85 INT233479 Gene_expression of Gprc5b 5 1 0.64 0.89 0.47
86 INT233475 Gene_expression of Gpr85 9 1 0.66 1.78 0.39
87 INT233492 Gene_expression of Gpr183 3 1 0.41 0.66 0.39
88 INT130036 Gene_expression of Emr1 2 7 0.75 1.47 0.38
89 INT233452 Positive_regulation of Gene_expression of Ccrl2 2 3 0.42 1.91 0.37
90 INT226649 Positive_regulation of Positive_regulation of Cxcr4 1 4 0.39 3.83 0.32
91 INT233498 Gene_expression of Gpr173 7 1 0.29 1.73 0.27
92 INT233481 Gene_expression of Gtpbp1 3 1 0.58 0.52 0.26
93 INT233461 Transcription of Lpar6 3 1 0.48 0.37 0.26
94 INT233472 Positive_regulation of Positive_regulation of Cx3cr1 1 1 0.41 0.32 0.19
95 INT233480 Gene_expression of S1pr2 3 4 0.50 0.46 0.15
96 INT233485 Transcription of Gpr84 2 1 0.47 0.42 0.15
97 INT233465 Regulation of Positive_regulation of Lpar6 1 1 0.30 0.07 0.11
98 INT233486 Negative_regulation of Lpar6 1 1 0.29 0.07 0.11
99 INT233491 Positive_regulation of Lpar6 1 1 0.34 0.07 0.11
100 INT233495 Regulation of Lpar6 1 1 0.30 0.07 0.11
101 INT233463 Positive_regulation of Gene_expression of Gpr84 2 1 0.61 0.49 0.11
102 INT162574 Gene_expression of Wnt5a 1 7 0.47 0.92 0.1
103 INT233483 Regulation of Gene_expression of Wnt5a 1 1 0.19 0.33 0.1
104 INT233467 Regulation of Itm2b 1 2 0.43 1.77 0.08
105 INT233462 Regulation of Fzd1 1 1 0.45 0.33 0.08
106 INT233470 Binding of S1pr2 1 1 0.24 0.2 0.07
107 INT233477 Regulation of Binding of S1pr2 1 1 0.29 0.2 0.07
108 INT233455 Negative_regulation of Itm2b 1 1 0.01 0.44 0.07
109 INT233476 Regulation of Gene_expression of Gpr85 1 1 0.39 0.39 0.07
110 INT233451 Negative_regulation of Htr2b 1 1 0.33 0.09 0
111 INT233490 Gene_expression of Ccrl1 1 1 0.45 0 0
112 INT233473 Negative_regulation of Gpr84 1 1 0.37 0.09 0
113 INT233468 Regulation of Gene_expression of Fpr1 1 1 0.32 0.08 0
114 INT233478 Negative_regulation of Fzd1 1 1 0.31 0.09 0
115 INT233454 Negative_regulation of Transcription of Lpar6 1 1 0.39 0.1 0
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