J:Immunopharmacology

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT21276 Binding of Oprd1 and Penk 9 2 0.54 1.14 8.28
2 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 1 0.00 0.45 0.82
3 INT90924 Oprd1 Regulation of Binding of Fgfr1op2 1 1 0.01 0 0.63
4 INT90925 Penk Regulation of Binding of Fgfr1op2 1 1 0.02 0 0.63
5 INT56235 Ifng Positive_regulation of Gene_expression of RT1-EC2 1 1 0.23 0.33 0.62
6 INT39210 TF Positive_regulation of Gene_expression of IL2 1 3 0.17 0.07 0.57
7 INT85511 Binding of KNG1 and Bdkrb2 1 1 0.54 0.51 0.4
8 INT39208 ALOX5 Regulation of Gene_expression of IL2 1 1 0.04 0.06 0.34
9 INT26669 Nanog Regulation of Binding of Tlyr1 1 1 0.02 0 0.28
10 INT39209 TMSB4XP5 Positive_regulation of Gene_expression of IL2 1 2 0.07 0 0.21
11 INT65744 Map3k7 Negative_regulation of Gene_expression of Il2 1 1 0.10 0.74 0.18
12 INT85445 NUBPL Negative_regulation of Gene_expression of CD40LG 1 1 0.01 0.31 0.16
13 INT39207 LBR Positive_regulation of Gene_expression of IL2 1 1 0.23 0 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
2 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
3 INT5660 Binding of Oprd1 1 477 0.48 71.86 342.06
4 INT9158 Gene_expression of Tnf 1 722 0.78 522.01 277.68
5 INT49750 Negative_regulation of CPOX 1 735 0.58 360.06 274.19
6 INT5972 Gene_expression of IL1B 1 948 0.78 510.91 263.97
7 INT738 Regulation of POMC 3 459 0.62 111.19 243.74
8 INT6293 Gene_expression of Oprm1 4 312 0.78 48.73 215.61
9 INT48955 Gene_expression of Nos2 8 753 0.78 403.87 208.08
10 INT2651 Positive_regulation of Pomc 1 403 0.70 95.72 206.24
11 INT2391 Negative_regulation of PTGS1 2 501 0.59 207.62 205.6
12 INT739 Negative_regulation of POMC 5 358 0.59 102.28 166.77
13 INT2640 Gene_expression of Pomc 2 424 0.78 120.72 155.37
14 INT5116 Gene_expression of IL2 17 670 0.78 291.13 146.69
15 INT48953 Positive_regulation of Nos2 3 486 0.70 239.85 131.87
16 INT695 Binding of POMC 3 304 0.48 56.66 126.85
17 INT11381 Positive_regulation of IL1B 2 330 0.70 209.31 100.9
18 INT940 Negative_regulation of Ptgs1 1 219 0.59 104.34 95.97
19 INT203 Positive_regulation of Pomc 1 257 0.70 90.56 92.84
20 INT6437 Binding of YY1 1 154 0.47 26.3 90.46
21 INT64636 Positive_regulation of Gene_expression of Nos2 4 242 0.70 147.52 79.53
22 INT5056 Gene_expression of IFNG 2 216 0.78 137.52 74.57
23 INT10359 Gene_expression of Ifng 4 159 0.78 79.6 72.14
24 INT8357 Gene_expression of KNG1 1 153 0.75 77.26 68.66
25 INT7134 Localization of KNG1 1 127 0.79 65.73 67.97
26 INT1603 Negative_regulation of Rtcd1 1 131 0.51 29.99 66.66
27 INT3375 Gene_expression of IGHE 3 535 0.77 387.47 65.46
28 INT24989 Positive_regulation of Cfp 1 125 0.61 29.55 64.9
29 INT11318 Gene_expression of Gtf3a 1 274 0.52 183.82 60.89
30 INT20266 Positive_regulation of Bdkrb1 2 60 0.69 63.64 56.59
31 INT1510 Binding of PDYN 1 94 0.48 4.68 56.44
32 INT78899 Gene_expression of CCL5 1 155 0.77 84.02 55.09
33 INT9234 Negative_regulation of Gene_expression of IL6 1 171 0.59 101.61 53.15
34 INT49017 Negative_regulation of Gene_expression of Nos2 5 169 0.59 80.64 52.67
35 INT12345 Gene_expression of Il2 2 142 0.78 59.17 51.21
36 INT5136 Negative_regulation of PDYN 1 71 0.59 11.22 51.14
37 INT4216 Gene_expression of CD40LG 1 328 0.78 256.02 44.23
38 INT4004 Gene_expression of IGHG3 1 321 0.71 221.03 42.33
39 INT13556 Gene_expression of CD4 1 367 0.78 230.82 41.74
40 INT5743 Localization of NA 2 104 0.59 14.35 35.29
41 INT6105 Positive_regulation of IL2 2 133 0.69 82.76 34.67
42 INT7675 Gene_expression of ENG 1 146 0.77 45.35 34.6
43 INT49214 Gene_expression of Cd4 1 269 0.78 154.22 34.05
44 INT48907 Positive_regulation of Gene_expression of Oprm1 3 53 0.69 8.55 33.52
45 INT64171 Regulation of CPOX 1 109 0.36 55.36 32.96
46 INT13186 Positive_regulation of Il4 3 113 0.68 71.22 31.4
47 INT9993 Positive_regulation of Gene_expression of IL2 11 131 0.69 46.27 30.04
48 INT5117 Negative_regulation of Gene_expression of IL2 2 118 0.59 52.33 29.96
49 INT61953 Transcription of Nos2 3 101 0.72 46.64 25.49
50 INT56224 Negative_regulation of Gene_expression of Ifng 2 40 0.58 23.34 25.08
51 INT70503 Regulation of Gene_expression of Nos2 4 71 0.62 44 24.01
52 INT25222 Positive_regulation of Gene_expression of Ifng 1 32 0.50 24.18 19.58
53 INT11803 Positive_regulation of Il2 1 62 0.70 31.44 18.93
54 INT67975 Gene_expression of Bdkrb2 1 38 0.68 21.69 17.94
55 INT2216 Gene_expression of SELL 1 92 0.77 59.29 17.71
56 INT30517 Negative_regulation of Bdkrb1 1 16 0.58 16.52 16.88
57 INT10000 Regulation of Gene_expression of IL2 5 56 0.45 15.33 16.2
58 INT9663 Protein_catabolism of PDYN 1 43 0.99 0.67 16.15
59 INT25223 Positive_regulation of Gene_expression of IFNG 1 41 0.67 36.97 15.89
60 INT10360 Positive_regulation of Ifng 4 33 0.68 21.73 15.19
61 INT27266 Regulation of Gene_expression of Pomc 1 41 0.62 6.74 14.59
62 INT85510 Positive_regulation of Bdkrb2 1 23 0.70 12.08 12.68
63 INT5057 Negative_regulation of Gene_expression of IFNG 1 23 0.58 8.33 12.3
64 INT9160 Negative_regulation of Ifng 1 31 0.58 16.37 11.84
65 INT20603 Positive_regulation of TNFRSF10B 1 40 0.67 32.61 11.44
66 INT14334 Negative_regulation of Il2 1 31 0.58 18.63 11.08
67 INT15804 Gene_expression of ISG20 1 83 0.75 44.33 10.58
68 INT12344 Negative_regulation of Gene_expression of Il2 1 28 0.59 15.53 10.23
69 INT17421 Negative_regulation of Alox5 2 41 0.57 15.23 10.05
70 INT70850 Positive_regulation of Transcription of Nos2 3 30 0.70 18.95 9.68
71 INT3988 Positive_regulation of Gene_expression of IGHE 1 98 0.68 91.46 9.61
72 INT15805 Gene_expression of TFRC 1 35 0.75 17.44 8.52
73 INT9573 Regulation of Bdkrb2 1 9 0.43 6.04 8.41
74 INT32210 Gene_expression of Mif 2 13 0.75 28.48 7.79
75 INT65295 Negative_regulation of Bdkrb2 1 9 0.37 6.36 6.49
76 INT23375 Binding of ENG 2 17 0.47 6.02 6.46
77 INT5186 Regulation of Ifng 1 11 0.45 8.78 5.9
78 INT3768 Negative_regulation of ANPEP 1 16 0.59 4.96 5.52
79 INT62041 Negative_regulation of Gene_expression of IGHE 1 37 0.58 37.86 5.27
80 INT18681 Gene_expression of Thy1 1 80 0.71 38.8 5.23
81 INT22597 Positive_regulation of TF 1 43 0.68 27.27 5.17
82 INT36237 Gene_expression of Ass1 1 11 0.24 2.31 4.38
83 INT48518 Gene_expression of ANPEP 1 51 0.78 22.88 4.18
84 INT13190 Gene_expression of Pbk 4 10 0.31 1.97 4.14
85 INT18662 Negative_regulation of Binding of PDYN 1 5 0.57 0.34 3.58
86 INT47201 Gene_expression of RT1-EC2 2 7 0.38 3.15 3.49
87 INT59986 Localization of BDKRB1 2 5 0.61 1.69 3.45
88 INT61952 Negative_regulation of Transcription of Nos2 3 17 0.54 5.1 3.34
89 INT53520 Binding of Igh-Dex 1 4 0.28 0.47 3.25
90 INT39867 Binding of Col2a1 1 9 0.35 7.65 3.18
91 INT56233 Gene_expression of RT1-Cl 3 1 0.18 1.25 2.36
92 INT11353 Gene_expression of SLC3A2 1 13 0.58 7.31 2.33
93 INT9995 Localization of C6orf25 1 13 0.69 6.48 2.29
94 INT13188 Negative_regulation of Gene_expression of Pbk 3 1 0.10 0 2.27
95 INT56229 Positive_regulation of Gene_expression of RT1-EC2 2 3 0.25 2.06 2.06
96 INT34579 Localization of IGLL1 2 7 0.69 2.63 1.89
97 INT14246 Regulation of Positive_regulation of IL1B 1 7 0.44 3.04 1.77
98 INT90926 Positive_regulation of GLI2 2 12 0.45 4.99 1.74
99 INT20982 Positive_regulation of SERPINB1 1 7 0.28 7.27 1.61
100 INT74818 Transcription of KNG1 2 6 0.67 2.71 1.59
101 INT56226 Positive_regulation of RT1-EC2 1 1 0.25 3.6 1.48
102 INT56228 Positive_regulation of Positive_regulation of Ifng 1 2 0.43 2.83 1.4
103 INT56230 Regulation of RT1-EC2 1 3 0.13 0.7 1.16
104 INT68018 Positive_regulation of CD2 2 3 0.65 0.79 1.13
105 INT52546 Gene_expression of NR3C2 1 10 0.65 1.09 1.1
106 INT79050 Negative_regulation of Localization of IGLL1 1 2 0.11 0.98 1.01
107 INT79862 Negative_regulation of Gene_expression of ANPEP 1 3 0.38 1.67 0.98
108 INT65294 Negative_regulation of Localization of BDKRB1 1 1 0.05 0 0.91
109 INT79861 Localization of ANPEP 1 4 0.62 0.54 0.86
110 INT57389 Positive_regulation of ARL4C 1 2 0.45 0.28 0.78
111 INT56227 Negative_regulation of Gene_expression of RT1-Cl 1 1 0.13 0.4 0.78
112 INT56225 Positive_regulation of Gene_expression of RT1-Cl 1 1 0.14 0.4 0.77
113 INT20983 Positive_regulation of ERLEC1 1 3 0.43 1.65 0.74
114 INT20480 Regulation of Localization of C6orf25 1 2 0.06 0.26 0.7
115 INT79051 Regulation of Localization of IGLL1 1 1 0.12 0.26 0.7
116 INT90917 Binding of Fgfr1op2 1 1 0.02 0 0.62
117 INT56232 Regulation of Positive_regulation of RT1-EC2 1 1 0.22 0.33 0.62
118 INT56231 Regulation of Positive_regulation of Ifng 1 1 0.39 0.33 0.62
119 INT66299 Binding of OR2AK2 1 1 0.03 0 0.49
120 INT85426 Transcription of CSPG4 1 1 0.23 1.03 0.3
121 INT26666 Binding of Tlyr1 1 1 0.02 0 0.27
122 INT65739 Gene_expression of Map3k7 2 1 0.54 1.41 0.25
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