J:Inflamm. Res.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT83616 Binding of IL6 and IL8 5 2 0.09 5.8 1.11
2 INT65007 DAK Negative_regulation of CTSA 1 1 0.03 0.35 0.48
3 INT65006 DAK Negative_regulation of ELANE 1 1 0.05 0.35 0.47
4 INT68557 ZNF697 Negative_regulation of PTGS1 1 1 0.02 0.59 0.33
5 INT96402 Binding of PTGS2 and TBXAS1 1 1 0.02 0.32 0.26
6 INT96401 Binding of PTGER1 and PTGS2 1 1 0.00 0.32 0.26
7 INT63453 Positive_regulation of PTGS1 Positive_regulation of Gene_expression of PLEKHM1 1 1 0.05 0.09 0.16
8 INT149185 Regulation of H2-Ab1 Regulation of Trpv1 1 1 0.34 0.52 0.08
9 INT149184 H2-Ab1 Regulation of Trpv1 1 1 0.34 0.52 0.08
10 INT140154 NOS1 Positive_regulation of NOS2 1 1 0.19 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 4 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 6 2008 0.81 518.3 1408.65
3 INT6483 Gene_expression of TNF 4 3152 0.78 2515.62 929.82
4 INT50058 Negative_regulation of Cpox 10 907 0.58 426.28 428.29
5 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
6 INT4758 Positive_regulation of Localization of Calca 6 557 0.70 138.55 411.04
7 INT64202 Positive_regulation of Trpv1 3 643 0.70 249.66 397.42
8 INT6056 Negative_regulation of Gene_expression of Fos 4 601 0.59 193.05 386.84
9 INT2540 Negative_regulation of Calca 3 538 0.59 172.11 384.38
10 INT6580 Negative_regulation of Ptgs1 6 929 0.59 381.53 376.26
11 INT2649 Regulation of Calca 1 433 0.62 146.05 330.95
12 INT5059 Positive_regulation of TNF 3 1050 0.70 896.51 322.81
13 INT34869 Negative_regulation of PTGS2 5 778 0.59 366.76 319.85
14 INT4941 Positive_regulation of Oprd1 1 345 0.70 74.26 304.41
15 INT9158 Gene_expression of Tnf 2 722 0.78 522.01 277.68
16 INT49750 Negative_regulation of CPOX 13 735 0.58 360.06 274.19
17 INT6852 Localization of TNF 1 883 0.81 705.95 270.84
18 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
19 INT1562 Localization of Crh 2 499 0.81 126.74 236.68
20 INT4759 Negative_regulation of Localization of Calca 2 294 0.59 82.62 226.45
21 INT6482 Positive_regulation of Gene_expression of TNF 1 659 0.70 569.88 210
22 INT48955 Gene_expression of Nos2 2 753 0.78 403.87 208.08
23 INT2391 Negative_regulation of PTGS1 12 501 0.59 207.62 205.6
24 INT50670 Gene_expression of CPOX 4 763 0.76 442.13 195.02
25 INT10194 Positive_regulation of IL6 3 702 0.70 600.62 183.38
26 INT15516 Gene_expression of Crp 1 711 0.77 615.33 173.09
27 INT2366 Binding of Cck 1 192 0.48 30.64 163.46
28 INT51921 Gene_expression of Cpox 1 501 0.73 229.81 157.81
29 INT1303 Negative_regulation of Npr1 1 278 0.55 35.1 156.78
30 INT6042 Binding of Oprm1 2 248 0.48 31.77 154.34
31 INT15515 Positive_regulation of Crp 2 700 0.70 604.24 150.15
32 INT5050 Regulation of Localization of Calca 3 149 0.62 41.25 148.57
33 INT5116 Gene_expression of IL2 3 670 0.78 291.13 146.69
34 INT9660 Regulation of TNF 2 363 0.62 312.94 139.99
35 INT48895 Gene_expression of Il10 1 333 0.78 221.2 138.52
36 INT60126 Regulation of Trpv1 2 186 0.62 85.53 133.4
37 INT48953 Positive_regulation of Nos2 6 486 0.70 239.85 131.87
38 INT49439 Gene_expression of Cpox 1 508 0.73 326.97 130.17
39 INT65054 Positive_regulation of Nfkb1 2 285 0.70 149.33 126.73
40 INT50674 Gene_expression of PTGS2 5 459 0.78 253.33 118.51
41 INT62124 Gene_expression of NOS1 2 444 0.78 218.08 114.85
42 INT48593 Positive_regulation of NOS1 2 420 0.68 226.15 114.71
43 INT10838 Positive_regulation of IL8 1 381 0.70 295.51 101.62
44 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
45 INT1760 Gene_expression of PTGER2 3 524 0.57 226.94 96.4
46 INT940 Negative_regulation of Ptgs1 1 219 0.59 104.34 95.97
47 INT77435 Positive_regulation of Nos2 1 343 0.70 208.49 91.43
48 INT48408 Gene_expression of ICAM1 1 494 0.78 340.08 88.6
49 INT54571 Positive_regulation of NFKB1 4 263 0.70 138.99 87.32
50 INT5610 Positive_regulation of Insr 2 140 0.69 37.26 86.24
51 INT4830 Binding of Trpv1 1 158 0.48 45.11 84.2
52 INT55944 Positive_regulation of Cpox 6 214 0.57 105.14 81.4
53 INT2431 Positive_regulation of Mpo 2 275 0.70 211.99 78.47
54 INT12476 Negative_regulation of TRPV1 1 124 0.59 47.95 77.98
55 INT98621 Regulation of Trpv1 1 121 0.62 79.24 75.23
56 INT48244 Gene_expression of Il4 1 172 0.76 132.38 73.42
57 INT49995 Positive_regulation of Gene_expression of Tnf 2 187 0.70 125.07 70.54
58 INT6849 Localization of IL1B 1 229 0.81 112.56 69.63
59 INT15613 Negative_regulation of Ptgs2 1 160 0.59 71.08 65.08
60 INT3950 Gene_expression of Ptger2 1 293 0.77 122.28 62.42
61 INT39153 Positive_regulation of PTGS2 9 182 0.70 96.16 60.6
62 INT5058 Positive_regulation of IFNA1 1 356 0.70 245.75 60.52
63 INT9196 Gene_expression of PTGS1 3 215 0.77 96.99 60.5
64 INT50672 Positive_regulation of CPOX 2 205 0.44 125.93 60.06
65 INT3920 Localization of Ldha 1 241 0.81 83.08 58.72
66 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
67 INT48891 Positive_regulation of Il10 2 143 0.70 101.42 56.72
68 INT52692 Gene_expression of Ptgs2 1 160 0.78 85.06 55.73
69 INT52800 Negative_regulation of Gene_expression of Tnf 1 142 0.59 92.27 55.47
70 INT48952 Negative_regulation of Nos2 1 204 0.59 101.73 53.15
71 INT9234 Negative_regulation of Gene_expression of IL6 1 171 0.59 101.61 53.15
72 INT5759 Positive_regulation of Ptgs1 4 127 0.69 53.45 53.04
73 INT52611 Negative_regulation of Ptgs2 1 142 0.59 66.31 52.71
74 INT53083 Gene_expression of Ptgs2 2 153 0.78 90.04 50.39
75 INT9210 Regulation of IL6 2 166 0.62 125.61 49.95
76 INT5307 Regulation of Tnf 1 87 0.62 78.71 43.4
77 INT48075 Positive_regulation of Il1b 1 71 0.67 48.63 40.48
78 INT49643 Gene_expression of Bdkrb1 1 39 0.78 46.49 40.21
79 INT2429 Negative_regulation of Mpo 2 128 0.59 93.76 39.57
80 INT55135 Positive_regulation of Gene_expression of PTGS2 2 137 0.70 80.32 38.46
81 INT6067 Positive_regulation of Positive_regulation of Oprd1 1 37 0.69 6.56 36.58
82 INT62827 Positive_regulation of ICAM1 3 184 0.70 180.95 36.28
83 INT65055 Negative_regulation of Nfkb1 1 83 0.58 44.85 34.94
84 INT79060 Gene_expression of NOS2 1 116 0.78 69.25 34.84
85 INT6105 Positive_regulation of IL2 2 133 0.69 82.76 34.67
86 INT65536 Negative_regulation of Positive_regulation of Nfkb1 1 77 0.59 38.86 33.33
87 INT64171 Regulation of CPOX 1 109 0.36 55.36 32.96
88 INT48693 Regulation of VEGFA 1 268 0.62 191.88 31.52
89 INT5418 Negative_regulation of Alox5 3 108 0.57 42.09 31.17
90 INT9993 Positive_regulation of Gene_expression of IL2 2 131 0.69 46.27 30.04
91 INT5300 Regulation of Insr 2 54 0.60 11.33 29.26
92 INT651 Positive_regulation of PTGS1 5 93 0.69 37.27 29.18
93 INT2389 Regulation of PTGS1 2 86 0.61 31.23 28.95
94 INT56072 Negative_regulation of NFKB1 2 94 0.59 53.16 28.19
95 INT6584 Negative_regulation of Pax3 1 31 0.39 14.64 27.97
96 INT8698 Localization of Nka1 1 50 0.78 5.8 27.67
97 INT1765 Positive_regulation of Gene_expression of PTGER2 1 140 0.51 68.68 27
98 INT2609 Localization of ELANE 1 111 0.81 50.22 26.63
99 INT65537 Positive_regulation of Positive_regulation of Nfkb1 2 52 0.67 30.6 26.35
100 INT1761 Positive_regulation of PTGER2 1 135 0.49 90.17 26.26
101 INT61953 Transcription of Nos2 5 101 0.72 46.64 25.49
102 INT9886 Gene_expression of Ptgs1 3 92 0.77 40.66 25.31
103 INT10835 Regulation of IL8 2 79 0.49 53.04 24.14
104 INT79061 Positive_regulation of NOS2 4 92 0.65 58.89 23.96
105 INT66026 Gene_expression of Cxcl1 6 74 0.78 31.87 23.37
106 INT50039 Positive_regulation of Il4 2 48 0.55 34.8 23.34
107 INT55170 Gene_expression of NFKB1 3 97 0.77 52.75 23.04
108 INT49196 Gene_expression of SELE 1 105 0.78 107.29 22.92
109 INT11077 Positive_regulation of Htr3a 1 63 0.67 15.61 22.7
110 INT21503 Binding of Ptgs1 1 45 0.48 15.6 22.29
111 INT5905 Negative_regulation of ELANE 2 113 0.59 47.43 22.09
112 INT8580 Gene_expression of ELANE 1 132 0.75 62.98 21.79
113 INT14700 Regulation of IFNA1 1 111 0.45 66.16 21.52
114 INT48692 Binding of VEGFA 1 345 0.48 210.3 21.31
115 INT52693 Positive_regulation of Gene_expression of Ptgs2 1 57 0.70 25.51 21.18
116 INT15796 Regulation of IL2 1 66 0.61 25.43 20.62
117 INT17848 Binding of PTGS2 3 70 0.46 32.1 20.6
118 INT96511 Negative_regulation of Positive_regulation of Trpv1 1 35 0.59 10.95 19.79
119 INT7994 Gene_expression of Lta 2 113 0.67 69.81 19.59
120 INT1764 Negative_regulation of Gene_expression of PTGER2 1 81 0.34 34.74 19.45
121 INT55335 Binding of Cpox 1 49 0.34 15.48 18.46
122 INT65260 Positive_regulation of Col7a1 1 95 0.69 61.73 18.42
123 INT61257 Gene_expression of Sele 8 79 0.77 70.97 17.78
124 INT62826 Negative_regulation of Gene_expression of ICAM1 1 75 0.58 46.39 17.72
125 INT61949 Regulation of Nos2 3 74 0.58 34.08 16.7
126 INT9069 Regulation of Htr3a 1 29 0.60 6.18 16.55
127 INT15202 Regulation of Tacr1 2 26 0.60 9.65 16.48
128 INT51576 Positive_regulation of Cxcl1 1 42 0.69 20.12 16.41
129 INT9197 Binding of PTGS1 1 44 0.48 18.48 16.26
130 INT10000 Regulation of Gene_expression of IL2 2 56 0.45 15.33 16.2
131 INT54572 Negative_regulation of Positive_regulation of NFKB1 1 46 0.58 21.45 15.47
132 INT4719 Positive_regulation of Nka1 1 27 0.67 4.16 15.42
133 INT22276 Gene_expression of TBXA2R 5 65 0.77 23.22 14.21
134 INT35120 Gene_expression of Sdcbp 2 68 0.67 21.33 13.96
135 INT23344 Gene_expression of Alox5 1 60 0.75 28.2 13.82
136 INT7997 Gene_expression of Ltc4s 2 51 0.76 34.28 13.8
137 INT91703 Negative_regulation of Myoz1 1 78 0.58 53.78 13.5
138 INT16635 Gene_expression of Ltb4r 6 27 0.64 17.05 13.21
139 INT51014 Transcription of IL2 1 42 0.71 21.56 12.7
140 INT83201 Gene_expression of NOS3 1 93 0.78 47.16 12.48
141 INT51028 Regulation of Il1b 2 28 0.60 21.15 12.47
142 INT59080 Negative_regulation of Gene_expression of PTGS2 1 55 0.58 22.92 12.39
143 INT4460 Regulation of Mpo 1 44 0.62 31.16 12.11
144 INT41313 Gene_expression of Gpx1 1 68 0.78 34.24 11.77
145 INT11894 Negative_regulation of Gene_expression of Ptger2 1 47 0.55 16.95 11.59
146 INT77677 Positive_regulation of Saa 1 30 0.49 33.19 11.18
147 INT48956 Negative_regulation of Positive_regulation of Nos2 1 34 0.46 13.15 11.15
148 INT6044 Regulation of Binding of Oprm1 1 16 0.61 3.01 11.11
149 INT14780 Regulation of Binding of Cck 1 9 0.49 4.33 10.83
150 INT52689 Regulation of Ptgs2 2 27 0.60 12.76 10.6
151 INT74272 Localization of CPOX 2 39 0.63 25.12 10.53
152 INT7995 Positive_regulation of Lta 1 28 0.66 14.98 9.8
153 INT80110 Regulation of Positive_regulation of TNF 1 34 0.44 25.79 9.78
154 INT95271 Negative_regulation of Nos3 3 46 0.53 24.1 9.71
155 INT6361 Localization of Edn1 1 30 0.81 19.09 9.7
156 INT16580 Negative_regulation of Htr2a 1 18 0.57 3.8 9.63
157 INT63341 Negative_regulation of ICAM1 2 42 0.59 30.45 9.5
158 INT23264 Negative_regulation of Positive_regulation of Ptgs1 1 16 0.39 8.47 8.9
159 INT113987 Localization of IK 1 29 0.23 16.73 8.25
160 INT15165 Positive_regulation of Localization of Nka1 1 7 0.66 1.19 7.78
161 INT52688 Transcription of Ptgs2 1 16 0.69 8.31 7.52
162 INT30729 Binding of Ptger2 1 36 0.29 7.66 7.35
163 INT49751 Negative_regulation of Positive_regulation of PTGS1 3 12 0.45 4.73 7.23
164 INT78404 Gene_expression of COX5A 1 24 0.75 9.73 7.07
165 INT10568 Regulation of H2-Ab1 1 9 0.20 1.86 6.79
166 INT89131 Negative_regulation of NOS2 1 20 0.58 9.68 6.56
167 INT65295 Negative_regulation of Bdkrb2 1 9 0.37 6.36 6.49
168 INT82254 Positive_regulation of Gene_expression of Cxcl1 2 17 0.69 9.95 6.47
169 INT83712 Transcription of Nos3 1 19 0.69 13.09 6.31
170 INT66227 Gene_expression of COX18 2 41 0.50 26.91 6.26
171 INT58484 Regulation of Il4 1 12 0.45 8.67 6.09
172 INT62525 Positive_regulation of SELE 3 38 0.70 46 5.25
173 INT59983 Regulation of BDKRB1 1 12 0.45 10.69 5.11
174 INT61950 Regulation of Positive_regulation of Nos2 1 17 0.43 9.01 4.87
175 INT10605 Positive_regulation of Ltc4s 1 21 0.68 17.22 4.8
176 INT62500 Transcription of Ptgs1 2 10 0.56 4.54 4.52
177 INT103155 Gene_expression of KDR 1 78 0.66 50.53 4.38
178 INT26239 Positive_regulation of Gene_expression of Lta 1 12 0.36 8.86 4.22
179 INT62526 Negative_regulation of SELE 2 17 0.51 15.24 4.19
180 INT52616 Negative_regulation of Positive_regulation of PTGS2 1 13 0.43 4.95 4.13
181 INT69967 Negative_regulation of Positive_regulation of CPOX 1 11 0.35 7.73 4.07
182 INT83991 Regulation of Nos3 1 25 0.44 9.89 4.06
183 INT35668 Gene_expression of PLEKHM1 4 21 0.10 3.1 3.95
184 INT68255 Regulation of Positive_regulation of IL8 1 12 0.41 5.71 3.91
185 INT19189 Localization of IL1A 1 14 0.78 9.02 3.78
186 INT27466 Negative_regulation of Kng1 2 7 0.10 7.79 3.56
187 INT50038 Positive_regulation of Il5 1 11 0.41 6.89 3.49
188 INT61952 Negative_regulation of Transcription of Nos2 1 17 0.54 5.1 3.34
189 INT16637 Negative_regulation of Gene_expression of Ltb4r 4 9 0.35 3.19 3.26
190 INT88220 Transcription of Bdkrb2 1 6 0.65 3.08 3.21
191 INT27446 Negative_regulation of CTSA 2 11 0.57 5.58 3.08
192 INT92814 Negative_regulation of NOS3 1 25 0.51 20.67 3.07
193 INT22277 Positive_regulation of Gene_expression of TBXA2R 1 13 0.69 5.95 2.92
194 INT91869 Transcription of NOS3 1 13 0.67 6.81 2.86
195 INT29835 Regulation of Gene_expression of TBXA2R 1 7 0.50 3.92 2.57
196 INT88225 Transcription of Ugt1a1 1 5 0.61 1.51 2.4
197 INT73671 Regulation of Gene_expression of Sele 1 8 0.45 7.01 2.39
198 INT4715 Positive_regulation of Xdh 1 20 0.69 6.57 2.28
199 INT66226 Positive_regulation of Gene_expression of COX18 2 10 0.31 4.41 2.11
200 INT44237 Negative_regulation of Gene_expression of PLEKHM1 3 7 0.07 0.94 2.06
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